Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hardwick SJ et al. | Glutathione (GSH) and the toxicity of oxidised low-density lipoprotein to human monocyte-macrophages. | 1999 | Free Radic. Res. | pmid:10193569 |
Oh-hashi K et al. | Dietary alpha-linolenate suppresses endotoxin-induced platelet-activating factor production in rat kidney. | 1999 | Lipids | pmid:10188594 |
Stewart JM et al. | Comparisons of the effects of temperature on the liver fatty acid binding proteins from hibernator and nonhibernator mammals. | 1998 | Biochem. Cell Biol. | pmid:10099779 |
Galli A et al. | High-level expression of rat class I alcohol dehydrogenase is sufficient for ethanol-induced fat accumulation in transduced HeLa cells. | 1999 | Hepatology | pmid:10094961 |
Zhang HY et al. | A high sucrose, high linoleic acid diet potentiates hypertension in the Dahl salt sensitive rat. | 1999 | Am. J. Hypertens. | pmid:10090346 |
Blask DE et al. | New actions of melatonin on tumor metabolism and growth. | 1999 Jan-Apr | Biol Signals Recept | pmid:10085462 |
Brodie AE et al. | Conjugated linoleic acid inhibits differentiation of pre- and post- confluent 3T3-L1 preadipocytes but inhibits cell proliferation only in preconfluent cells. | 1999 | J. Nutr. | pmid:10082762 |
Olsson U et al. | Fatty acids modulate the composition of extracellular matrix in cultured human arterial smooth muscle cells by altering the expression of genes for proteoglycan core proteins. | 1999 | Diabetes | pmid:10078565 |
Chancharme L et al. | Cholesteryl ester hydroperoxide lability is a key feature of the oxidative susceptibility of small, dense LDL. | 1999 | Arterioscler. Thromb. Vasc. Biol. | pmid:10073990 |
Dhiman TR et al. | Conjugated linoleic acid content of milk and cheese from cows fed extruded oilseeds. | 1999 | J. Dairy Sci. | pmid:10068962 |