Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Child Nutrition Disorders D015362 1 associated lipids
Refeeding Syndrome D055677 1 associated lipids
Pellagra D010383 1 associated lipids
Refractive Errors D012030 1 associated lipids
Carcinoma, Krebs 2 D002287 1 associated lipids
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
Onchocerciasis D009855 1 associated lipids
Malaria, Cerebral D016779 1 associated lipids
Liposarcoma D008080 1 associated lipids
Gastroschisis D020139 1 associated lipids
Fat Necrosis D005218 1 associated lipids
Facial Nerve Diseases D005155 1 associated lipids
Darier Disease D007644 2 associated lipids
Aneurysm D000783 2 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Circoviridae Infections D018173 2 associated lipids
Leptospirosis D007922 2 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Lymphopenia D008231 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Suardíaz R et al. An insight into the regiospecificity of linoleic acid peroxidation catalyzed by mammalian 15-lipoxygenases. 2013 J Phys Chem B pmid:23496802
Cardoso S et al. UCP2 and ANT differently modulate proton-leak in brain mitochondria of long-term hyperglycemic and recurrent hypoglycemic rats. 2013 J. Bioenerg. Biomembr. pmid:23504111
Stamey Lanier J et al. Mammary uptake of fatty acids supplied by intravenous triacylglycerol infusion to lactating dairy cows. 2013 Lipids pmid:23504269
Jung CH et al. The preventive effect of uncarboxylated osteocalcin against free fatty acid-induced endothelial apoptosis through the activation of phosphatidylinositol 3-kinase/Akt signaling pathway. 2013 Metab. Clin. Exp. pmid:23639572
Franco-Pons N et al. Fat necrosis generates proinflammatory halogenated lipids during acute pancreatitis. 2013 Ann. Surg. pmid:22964727
Ndhlala AR et al. Anti-oxidative and cholinesterase inhibitory effects of leaf extracts and their isolated compounds from two closely related Croton species. 2013 Molecules pmid:23377133
Chen CS et al. Preference for linoleic acid in obesity-prone and obesity-resistant rats is attenuated by the reduction of CD36 on the tongue. 2013 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:24154509
Li P et al. Effect of non-esterified fatty acids on fatty acid metabolism-related genes in calf hepatocytes cultured in vitro. 2013 Cell. Physiol. Biochem. pmid:24335176
Ramsden CE et al. Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans. 2012 Oct-Nov Prostaglandins Leukot. Essent. Fatty Acids pmid:22959954
Mysiakina IS et al. [Lipid composition of fungus Mucor hiemalis mycelium grown in the presence of trehalose, triacylglycerols, and itraconazole]. 2012 Nov-Dec Mikrobiologiia pmid:23610922
Mysiakina IS et al. [Effect of biological factors on morphogenesis, growth, and lipid composition of fungus Mucor hiemalis mycelium]. 2012 Nov-Dec Mikrobiologiia pmid:23610923
Alinezhad H et al. Biochemical activities of acetone extracts of Hyssopus angustifolius. 2012 Jul-Aug Acta Pol Pharm pmid:22876603
Moghaddam AH et al. Antioxidant, antihemolytic and nephroprotective activity of aqueous extract of Diospyros lotus seeds. 2012 Jul-Aug Acta Pol Pharm pmid:22876611
Kuipers RS et al. Fetal intrauterine whole body linoleic, arachidonic and docosahexaenoic acid contents and accretion rates. 2012 Jan-Feb Prostaglandins Leukot. Essent. Fatty Acids pmid:22115845
Brenna T Tissue-specific LCPUFA accretion in fetal humans. 2012 Jan-Feb Prostaglandins Leukot. Essent. Fatty Acids pmid:22078006
Chivandi E et al. Suppression of Caco-2 and HEK-293 cell proliferation by Kigelia africana, Mimusops zeyheri and Ximenia caffra seed oils. 2012 Jan-Feb In Vivo pmid:22210722
Johnson GH and Fritsche K Effect of dietary linoleic acid on markers of inflammation in healthy persons: a systematic review of randomized controlled trials. 2012 J Acad Nutr Diet pmid:22889633
Sabir A et al. The fatty acid and tocopherol constituents of the seed oil extracted from 21 grape varieties (Vitis spp.). 2012 J. Sci. Food Agric. pmid:22271548
Ties P and Barringer S Influence of lipid content and lipoxygenase on flavor volatiles in the tomato peel and flesh. 2012 J. Food Sci. pmid:22757705
Lan M et al. [GC-MS analysis of chemical components in seeds oil from Croton tiglium]. 2012 Zhong Yao Cai pmid:23252276
Nandi S et al. Effect of prostaglandin producing modulators on in vitro growth of buffalo uterine epithelial cells. 2012 Theriogenology pmid:22115808
Xue C et al. Differences in lipid characteristics among populations: low-temperature adaptability of ayu, Plecoglossus altivelis. 2012 Lipids pmid:22120618
Jernerén F et al. Linolenate 9R-dioxygenase and allene oxide synthase activities of Lasiodiplodia theobromae. 2012 Lipids pmid:22048860
Rohr-Udilova N et al. Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma. 2012 Hepatology pmid:22105228
Coimbra MC and Jorge N Fatty acids and bioactive compounds of the pulps and kernels of Brazilian palm species, guariroba (Syagrus oleraces), jerivá (Syagrus romanzoffiana) and macaúba (Acrocomia aculeata). 2012 J. Sci. Food Agric. pmid:21922463
Shah BP et al. TRPM5 is critical for linoleic acid-induced CCK secretion from the enteroendocrine cell line, STC-1. 2012 Am. J. Physiol., Cell Physiol. pmid:21998136
Marincola FC et al. A metabolomic study of preterm human and formula milk by high resolution NMR and GC/MS analysis: preliminary results. 2012 J. Matern. Fetal. Neonatal. Med. pmid:23025771
Ruparel S et al. The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain. 2012 Mol Pain pmid:23006841
Osuji GO et al. Molecular modeling of metabolism for allergen-free low linoleic acid peanuts. 2012 Appl. Biochem. Biotechnol. pmid:22918723
Kim YS et al. In vitro protective effects of Thymus quinquecostatus Celak extracts on t-BHP-induced cell damage through antioxidant activity. 2012 Food Chem. Toxicol. pmid:22921350
Ezebuo FC et al. Effects of sodium dodecyl sulphate on enhancement of lipoxygenase activity of hemoglobin. 2012 Indian J. Exp. Biol. pmid:23986967
Mukherjee S et al. NAD(P)H cytochrome b5 oxidoreductase deficiency in Leishmania major results in impaired linoleate synthesis followed by increased oxidative stress and cell death. 2012 J. Biol. Chem. pmid:22923617
Le Maux S et al. β-Lactoglobulin as a molecular carrier of linoleate: characterization and effects on intestinal epithelial cells in vitro. 2012 J. Agric. Food Chem. pmid:22924475
Dubey V et al. Appraisal of conjugated linoleic acid production by probiotic potential of Pediococcus spp. GS4. 2012 Appl. Biochem. Biotechnol. pmid:22971829
Stachowska E et al. Conjugated linoleic acid isomers may diminish human macrophages adhesion to endothelial surface. 2012 Int J Food Sci Nutr pmid:21721848
Toomik P et al. The effect of tenderizing acids on linoleic acid oxidation during marination of pork. 2012 Meat Sci. pmid:22762994
Amoo SO et al. Antioxidant and acetylcholinesterase-inhibitory properties of long-term stored medicinal plants. 2012 BMC Complement Altern Med pmid:22769046
Park EY et al. Effects of peptide fractions with different isoelectric points from wheat gluten hydrolysates on lipid oxidation in pork meat patties. 2012 J. Agric. Food Chem. pmid:22747172
Sajid ZI et al. Antioxidant, antimicrobial properties and phenolics of different solvent extracts from bark, leaves and seeds of Pongamia pinnata (L.) Pierre. 2012 Molecules pmid:22466852
Shindo T et al. Effective induction of oral anaphylaxis to ovalbumin in mice sensitized by feeding of the antigen with aid of oil emulsion and salicylate. 2012 J Toxicol Sci pmid:22467021
Gören AC et al. Fatty acid composition and chemotaxonomic evaluation of species of Stachys. 2012 Nat. Prod. Res. pmid:21859257
Reynolds CM et al. Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance. 2012 Mol Nutr Food Res pmid:22700321
Ladeira MM et al. Lipids in the diet and the fatty acid profile in beef: a review and recent patents on the topic. 2012 Recent Pat Food Nutr Agric pmid:22702746
Hill S et al. Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation. 2012 Free Radic. Biol. Med. pmid:22705367
Kamitani S et al. Differences between group X and group V secretory phospholipase A(2) in lipolytic modification of lipoproteins. 2012 Cell. Mol. Biol. Lett. pmid:22706677
Roongpisuthipong W et al. Essential fatty acid deficiency while a patient receiving fat regimen total parenteral nutrition. 2012 BMJ Case Rep pmid:22707694
Ren HT et al. Influence of dietary fatty acids on muscle fatty acid composition and expression levels of Δ6 desaturase-like and Elovl5-like elongase in common carp (Cyprinus carpio var. Jian). 2012 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:22677415
Xie J et al. Composition of fatty oils from semen ziziphi spinosae and its cardiotonic effect on isolated toad hearts. 2012 Nat. Prod. Res. pmid:21707231
Sultana B et al. Investigation on the antioxidant activity of leaves, peels, stems bark, and kernel of mango (Mangifera indica L.). 2012 J. Food Sci. pmid:22860576
Wakabayashi K et al. Species differences in toxicokinetic parameters of glycidol after a single dose of glycidol or glycidol linoleate in rats and monkeys. 2012 J Toxicol Sci pmid:22863850