Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Geer BW et al. | The effect of dietary ethanol on the composition of lipids of Drosophila melanogaster larvae. | 1986 | Biochem. Genet. | pmid:2938574 |
| Boberg M et al. | High content of dietary linoleic acid does not reduce platelet reactivity in patients with hyperlipoproteinaemia. | 1986 | Eur. J. Clin. Invest. | pmid:2938965 |
| Orchard S et al. | Poison ivy/oak dermatitis. Use of polyamine salts of a linoleic acid dimer for topical prophylaxis. | 1986 | Arch Dermatol | pmid:2942115 |
| May V and Eipper BA | Long term culture of primary rat pituitary adrenocorticotropin/endorphin-producing cells in serum-free medium. | 1986 | Endocrinology | pmid:3004908 |
| Kühn H et al. | The stoichiometry of oxygen uptake and conjugated diene formation during the dioxygenation of linoleic acid by the pure reticulocyte lipoxygenase. Evidence for aerobic hydroperoxidase activity. | 1986 | Biochim. Biophys. Acta | pmid:3006782 |
| Murphy MG | Studies of the regulation of basal adenylate cyclase activity by membrane polyunsaturated fatty acids in cultured neuroblastoma. | 1986 | J. Neurochem. | pmid:3011993 |
| Skogh M | Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids) | 1986 | J. Am. Acad. Dermatol. | pmid:3013957 |
| Kher V et al. | Protective effect of polyunsaturated fatty acid supplementation in apoferritin induced murine glomerulonephritis. | 1986 | Prostaglandins Leukot Med | pmid:3014561 |
| Alexander JW et al. | The importance of lipid type in the diet after burn injury. | 1986 | Ann. Surg. | pmid:3015058 |
| Yamamoto T et al. | Purification of the two forms of the high-molecular-weight neutral proteinase ingensin from rat liver. | 1986 | Biochim. Biophys. Acta | pmid:3015226 |
| Kelly RA et al. | Identification of NaK-ATPase inhibitors in human plasma as nonesterified fatty acids and lysophospholipids. | 1986 | J. Biol. Chem. | pmid:3017943 |
| Kääpä P et al. | Dietary fatty acids and platelet thromboxane production in puerperal women and their offspring. | 1986 | Am. J. Obstet. Gynecol. | pmid:3089014 |
| Maddaiah VT and Clejan S | Growth hormone and liver mitochondria: time course of effects on respiration and fatty acid composition in hypophysectomized rats. | 1986 | Endocrinology | pmid:2941269 |
| Connor HD et al. | A search for oxygen-centered free radicals in the lipoxygenase/linoleic acid system. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3026385 |
| Stymne S and Stobart AK | Biosynthesis of gamma-linolenic acid in cotyledons and microsomal preparations of the developing seeds of common borage (Borago officinalis). | 1986 | Biochem. J. | pmid:3028375 |
| van Staveren WA et al. | Validity of the fatty acid composition of subcutaneous fat tissue microbiopsies as an estimate of the long-term average fatty acid composition of the diet of separate individuals. | 1986 | Am. J. Epidemiol. | pmid:3946391 |
| Nijssen JG and van den Bosch H | Cytosol-stimulated remodeling of phosphatidylcholine in rat lung microsomes. | 1986 | Biochim. Biophys. Acta | pmid:3947653 |
| Kryvi H et al. | Effects of essential fatty acid deficiency on mitochondria and peroxisomes in rat hepatocytes with special reference to a partially hydrogenated fish oil diet. | 1986 | Biochim. Biophys. Acta | pmid:3947675 |
| De Villiers M and Lochner A | Mitochondrial Ca2+ fluxes: role of free fatty acids, acyl-CoA and acylcarnitine. | 1986 | Biochim. Biophys. Acta | pmid:3955069 |
| Fressinaud C et al. | Fatty acid composition of endoneurium and perineurium from adult rat sciatic nerve. | 1986 | J. Neurochem. | pmid:3958717 |
| Becker W and Bruce A | Retention of linoleic acid in carcass lipids of rats fed different levels of essential fatty acids. | 1986 | Lipids | pmid:3959773 |
| Otsuki T et al. | Two geometrical isomers of linoleic acid: improved total syntheses. | 1986 | Lipids | pmid:3959777 |
| Ishiura S et al. | Reticulocyte lipoxygenase, ingensin, and ATP-dependent proteolysis. | 1986 | FEBS Lett. | pmid:3086125 |
| Kanofsky JR and Axelrod B | Singlet oxygen production by soybean lipoxygenase isozymes. | 1986 | J. Biol. Chem. | pmid:3080416 |
| Renner F et al. | Effect of saturated and unsaturated lipid on the composition of mesenteric triglyceride-rich lipoproteins in the rat. | 1986 | J. Lipid Res. | pmid:3083032 |
| Innis SM | Effect of total parenteral nutrition with linoleic acid-rich emulsions on tissue omega 6 and omega 3 fatty acids in the rat. | 1986 | Lipids | pmid:3083173 |
| Kanazawa K et al. | The effect of orally administered secondary autoxidation products of linoleic acid on the activity of detoxifying enzymes in the rat liver. | 1986 | Biochim. Biophys. Acta | pmid:3768385 |
| Montalto MB and Benson JD | Nutrient intakes of older infants: effect of different milk feedings. | 1986 | J Am Coll Nutr | pmid:3771945 |
| Feingold KR et al. | Effect of essential fatty acid deficiency on cutaneous sterol synthesis. | 1986 | J. Invest. Dermatol. | pmid:3772153 |
| Jensen GE and Clausen J | Glutathione peroxidase activity, associated enzymes and substrates in blood cells from patients with multiple sclerosis--effects of antioxidant supplementation. | 1986 | Acta Pharmacol Toxicol (Copenh) | pmid:3776606 |
| Kapoulas VM and Andrikopoulos NK | Detection of olive oil adulteration with linoleic acid-rich oils by reversed-phase high-performance liquid chromatography. | 1986 | J. Chromatogr. | pmid:3782323 |
| Jones DB et al. | Indirect evidence of impairment of platelet desaturase enzymes in diabetes mellitus. | 1986 | Horm. Metab. Res. | pmid:3013745 |
| Masuda Y et al. | The mode of enhanced enteral absorption of macromolecules by lipid-surfactant mixed micelles. I. | 1986 | J. Pharmacobio-dyn. | pmid:3820056 |
| Wertz PW and Downing DT | Linoleate content of epidermal acylglucosylceramide in newborn, growing and mature mice. | 1986 | Biochim. Biophys. Acta | pmid:3707979 |
| Vericel E et al. | Effects of linoleic acid and gamma-linolenic acid intake on platelet functions in elderly people. | 1986 | Thromb. Res. | pmid:3715813 |
| Hajarine M and Lagarde M | Studies on polyenoic acid incorporation into human platelet lipid stores: interactions with linoleic and arachidonic acids. | 1986 | Biochim. Biophys. Acta | pmid:3719006 |
| Dowd TC et al. | Diabetic retinopathy: different risk factors for exudates and haemorrhages. | 1986 | Int Ophthalmol | pmid:3721707 |
| Awad AB and Chattopadhyay JP | Effect of dietary saturated fatty acids on intracellular free fatty acids and kinetic properties of hormone-sensitive lipase of rat adipocytes. | 1986 | J. Nutr. | pmid:3723204 |
| Hansen HS and Jensen B | Urinary excretion of arginine-vasopressin and prostaglandin E2 in essential fatty acid-deficient rats after oral supplementation with unsaturated fatty acid esters. | 1986 | J. Nutr. | pmid:3080561 |
| Gabor H and Abraham S | Effect of dietary menhaden oil on tumor cell loss and the accumulation of mass of a transplantable mammary adenocarcinoma in BALB/c mice. | 1986 | J. Natl. Cancer Inst. | pmid:3458958 |
| Elliott GR et al. | Linoleic and dihomo-gamma-linolenic acids modulate granuloma growth and granuloma macrophage eicosanoid release. | 1986 | Eur. J. Pharmacol. | pmid:3460810 |
| Nijssen JG and van den Bosch H | Coenzyme A-mediated transacylation of sn-2 fatty acids from phosphatidylcholine in rat lung microsomes. | 1986 | Biochim. Biophys. Acta | pmid:3081034 |
| Leat WM et al. | Retinal function in rats and guinea-pigs reared on diets low in essential fatty acids and supplemented with linoleic or linolenic acids. | 1986 | Ann. Nutr. Metab. | pmid:2872851 |
| Jenkins KJ and Kramer JK | Influence of low linoleic and linolenic acids in milk replacer on calf performance and lipids in blood plasma, heart, and liver. | 1986 | J. Dairy Sci. | pmid:2873158 |
| Siguel EN et al. | Monitoring the optimal infusion of intravenous lipids. Detection of essential fatty acid deficiency. | 1986 | Arch. Pathol. Lab. Med. | pmid:2875703 |
| Morson LA and Clandinin MT | Diets varying in linoleic and linolenic acid content alter liver plasma membrane lipid composition and glucagon-stimulated adenylate cyclase activity. | 1986 | J. Nutr. | pmid:2879899 |
| Siegel I et al. | Inhibition of sperm motility and agglutination of sperm cells by free fatty acids in whole semen. | 1986 | Fertil. Steril. | pmid:2868925 |
| Tabachnick M and Korcek L | Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. | 1986 | Biochim. Biophys. Acta | pmid:2869786 |
| Iriyama K et al. | Metabolism of non-protein energy-substrates in septic rats receiving parenteral nutrition. | 1986 Jan-Mar | Int Surg | pmid:3087901 |
| Koletzko B et al. | Comparison of fatty acid composition of plasma lipid fractions in well-nourished Nigerian and German infants and toddlers. | 1986 Jul-Aug | J. Pediatr. Gastroenterol. Nutr. | pmid:3090220 |
| Kaunitz H | Medium chain triglycerides (MCT) in aging and arteriosclerosis. | 1986 Mar-Apr | J. Environ. Pathol. Toxicol. Oncol. | pmid:3519928 |
| Kummerow FA | Dietary effects of trans fatty acids. | 1986 Mar-Apr | J. Environ. Pathol. Toxicol. Oncol. | pmid:3519929 |
| Fukuzumi K | Relationship between lipoperoxides and diseases. | 1986 Mar-Apr | J. Environ. Pathol. Toxicol. Oncol. | pmid:3519933 |
| Olivi O et al. | [A new and original therapy for seborrheic dermatitis]. | 1986 May-Jun | Pediatr Med Chir | pmid:2947051 |
| Lester LA et al. | Supplemental parenteral nutrition in cystic fibrosis. | 1986 May-Jun | JPEN J Parenter Enteral Nutr | pmid:3086588 |
| Thomson AB et al. | A high linoleic acid diet diminishes enhanced intestinal uptake of sugars in diabetic rats. | 1987 | Am. J. Physiol. | pmid:3826353 |
| Young MR et al. | Stimulation of hematopoiesis and bone marrow suppressor cells by the subcutaneous injection of linoleic acid. | 1987 | Cell. Immunol. | pmid:2953447 |
| Ringertz B et al. | High dietary linoleic acid content modulates neutrophil function in rats. | 1987 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2960199 |
| Strauss JS et al. | The effect of 13-cis-retinoic acid on sebaceous glands. | 1987 | Arch Dermatol | pmid:2960273 |
| Bjerve KS et al. | Alpha-linolenic acid deficiency in man: effect of ethyl linolenate on plasma and erythrocyte fatty acid composition and biosynthesis of prostanoids. | 1987 | Am. J. Clin. Nutr. | pmid:3310599 |
| Wertz PW et al. | Essential fatty acids and epidermal integrity. | 1987 | Arch Dermatol | pmid:3310912 |
| Szekeres L | Cardioprotection by anti-ischaemic and cytoprotective drugs. | 1987 | Basic Res. Cardiol. | pmid:3311014 |
| Levay-Young BK et al. | Linoleic acid, but not cortisol, stimulates accumulation of casein by mouse mammary epithelial cells in serum-free collagen gel culture. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3317407 |
| Sacks FM et al. | Effect of linoleic and oleic acids on blood pressure, blood viscosity, and erythrocyte cation transport. | 1987 | J Am Coll Nutr | pmid:3584738 |
| Taylor AJ et al. | An alternative explanation for the changes in erythrocyte fatty acids observed in diabetes mellitus. | 1987 | Clin. Chem. | pmid:3119255 |
| Murphy MG et al. | Effects of membrane polyunsaturated fatty acids on opiate peptide inhibition of basal and prostaglandin E1-stimulated cyclic AMP formation in intact N1E-115 neuroblastoma cells. | 1987 | Biochem. Pharmacol. | pmid:2825714 |
| Wehrmann W et al. | [Clinical and immune-modulating effects of the treatment with unsaturated fatty acids in atopic dermatitis]. | 1987 | Z. Hautkr. | pmid:2831674 |
| Hagve TA and Christophersen BO | In vitro effects of alpha-bromopalmitate on metabolism of essential fatty acids studied in isolated rat hepatocytes: sex differences. | 1987 | Biochim. Biophys. Acta | pmid:3099848 |
| Salafsky B and Fusco AC | Schistosoma mansoni: a comparison of secreted vs nonsecreted eicosanoids in developing schistosomulae and adults. | 1987 | Exp. Parasitol. | pmid:2824233 |
| Mikhailidis DP et al. | High content of dietary linoleic acid does not reduce platelet reactivity in patients with hyperlipoproteinaemia. | 1987 | Eur. J. Clin. Invest. | pmid:3106056 |
| MartÃnez M and Ballabriga A | Effects of parenteral nutrition with high doses of linoleate on the developing human liver and brain. | 1987 | Lipids | pmid:3106740 |
| Ludwig P et al. | Modelling the reaction mechanism of the reticulocyte lipoxygenase. | 1987 | Biomed. Biochim. Acta | pmid:3109405 |
| Bomalaski JS et al. | Alteration of uptake and distribution of eicosanoid precursor fatty acids by aspirin. | 1987 | Biochem. Pharmacol. | pmid:3117063 |
| Cook HW and Spence MW | Studies of the modulation of essential fatty acid metabolism by fatty acids in cultured neuroblastoma and glioma cells. | 1987 | Biochim. Biophys. Acta | pmid:3105586 |
| Griffin JF et al. | Recognition of cervical neoplasia by the estimation of a free-radical reaction product (octadeca-9,11-dienoic acid) in biopsy material. | 1987 | Clin. Chim. Acta | pmid:3568417 |
| Tay SK et al. | Recognition of cervical neoplasia by the estimation of a free-radical reaction product (octadeca-9,11-dienoic acid) in exfoliated cells. | 1987 | Clin. Chim. Acta | pmid:3568418 |
| Quik M | Evidence for an involvement of membrane lipids in the control of neuronal nicotinic receptor function using bungarotoxin II-S1. | 1987 | J. Neurochem. | pmid:3106571 |
| Bandyopadhyay GK et al. | Linoleate metabolites enhance the in vitro proliferative response of mouse mammary epithelial cells to epidermal growth factor. | 1987 | J. Biol. Chem. | pmid:3102474 |
| Kaneko T et al. | Lethal effects of a linoleic acid hydroperoxide and its autoxidation products, unsaturated aliphatic aldehydes, on human diploid fibroblasts. | 1987 | Chem. Biol. Interact. | pmid:3664790 |
| Das UN et al. | Uptake and distribution of cis-unsaturated fatty acids and their effect on free radical generation in normal and tumor cells in vitro. | 1987 | Free Radic. Biol. Med. | pmid:3040539 |
| Nilsson A et al. | Absorption and lymphatic transport of exogenous and endogenous arachidonic and linoleic acid in the rat. | 1987 | Am. J. Physiol. | pmid:3109253 |
| Willett WC et al. | Dietary fat and the risk of breast cancer. | 1987 | N. Engl. J. Med. | pmid:3785347 |
| Jensen E et al. | Cell-density-dependent uptake of chylomicron remnants in rat hepatocyte monolayers. Effects of compactin and mevalonic acid. | 1987 | Biochim. Biophys. Acta | pmid:3790613 |
| del Nido PJ et al. | Evidence of myocardial free radical injury during elective repair of tetralogy of Fallot. | 1987 | Circulation | pmid:2959398 |
| Emken EA et al. | Metabolism of cis-12-octadecenoic acid and trans-9,trans-12-octadecadienoic acid and their influence on lipogenic enzyme activities in mouse liver. | 1987 | Biochim. Biophys. Acta | pmid:3580379 |
| Mackie BS et al. | Melanoma and dietary lipids. | 1987 | Nutr Cancer | pmid:3110746 |
| Cunnane SC | Hepatic triacylglycerol accumulation induced by ethanol and carbon tetrachloride: interactions with essential fatty acids and prostaglandins. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3032013 |
| Haines KA et al. | The leukotriene B4 paradox: neutrophils can, but will not, respond to ligand-receptor interactions by forming leukotriene B4 or its omega-metabolites. | 1987 | Biochem. J. | pmid:3032161 |
| Coronary heart disease and linoleic acid content of adipose tissue. | 1987 | Nutr. Rev. | pmid:3332709 | |
| Tischinger-Wagner H et al. | [Oxidative degradation of linoleic acid methyl ester in suspensions of inorganic excipients. 1. Auto-oxidation in the presence of silicic acid products and aluminum oxide]. | 1987 | Pharmazie | pmid:2823296 |
| Gyllenhammar H et al. | Dietary essential fatty acid deficiency in rats is accompanied by impairments in neutrophil function and leukotriene B4 generation. | 1987 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2823572 |
| Clementz T et al. | Membrane potential, lipid regulation and adenylate energy charge in acyl chain modified Acholeplasma laidlawii. | 1987 | Biochim. Biophys. Acta | pmid:3567184 |
| Strannegård IL et al. | Essential fatty acids in serum lecithin of children with atopic dermatitis and in umbilical cord serum of infants with high or low IgE levels. | 1987 | Int. Arch. Allergy Appl. Immunol. | pmid:3570505 |
| Heifets M et al. | Effect of dietary lipids on renal function in rats with subtotal nephrectomy. | 1987 | Kidney Int. | pmid:3669493 |
| Hubbard NE and Erickson KL | Enhancement of metastasis from a transplantable mouse mammary tumor by dietary linoleic acid. | 1987 | Cancer Res. | pmid:3677068 |
| Hachey DL et al. | Human lactation: maternal transfer of dietary triglycerides labeled with stable isotopes. | 1987 | J. Lipid Res. | pmid:3681142 |
| Wan JM and Grimble RF | Effect of dietary linoleate content on the metabolic response of rats to Escherichia coli endotoxin. | 1987 | Clin. Sci. | pmid:3545648 |
| Bruneau C et al. | Influence of lipid environment on insulin binding in cultured hepatoma cells. | 1987 | Biochim. Biophys. Acta | pmid:3552053 |
| Loesberg C et al. | Effects of dietary poly-unsaturated fatty acids on tracheal histaminergic and cholinergic responsiveness in experimental models of bronchial hypersensitivity and hyperreactivity. | 1987 | Agents Actions | pmid:2895570 |
| Bruneau C et al. | Modifications of cellular lipids induce insulin resistance in cultured hepatoma cells. | 1987 | Biochim. Biophys. Acta | pmid:3552054 |