Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Bylund J et al. | Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9435160 |
Kaur K et al. | (Carboxyalkyl)pyrroles in human plasma and oxidized low-density lipoproteins. | 1997 | Chem. Res. Toxicol. | pmid:9437530 |
Berry H et al. | Oxygen concentration determines regiospecificity in soybean lipoxygenase-1 reaction via a branched kinetic scheme. | 1998 | J. Biol. Chem. | pmid:9446584 |
Hamberg M | Stereochemistry of oxygenation of linoleic acid catalyzed by prostaglandin-endoperoxide H synthase-2. | 1998 | Arch. Biochem. Biophys. | pmid:9448728 |
Colquhoun A and Curi R | Regulation of tumour cell fatty acid oxidation by n-6 polyunsaturated fatty acids. | 1997 | Biochem. Soc. Trans. | pmid:9450108 |
Maheswari SU et al. | Inhibition of Fe(II) catalyzed linoleic acid oxidation and DNA damage by phosvitin. | 1997 | Mol. Cell. Biochem. | pmid:9450644 |
van Roermund CW et al. | Peroxisomal beta-oxidation of polyunsaturated fatty acids in Saccharomyces cerevisiae: isocitrate dehydrogenase provides NADPH for reduction of double bonds at even positions. | 1998 | EMBO J. | pmid:9450993 |
Dadras SS et al. | Implication of hydrogen peroxide generation and apoptosis in the neoplastic transformation of mouse fibroblasts overexpressing peroxisomal fatty acyl-CoA oxidase. | 1998 | Int. J. Oncol. | pmid:9454884 |
Devor DC and Frizzell RA | Modulation of K+ channels by arachidonic acid in T84 cells. II. Activation of a Ca(2+)-independent K+ channel. | 1998 | Am. J. Physiol. | pmid:9458723 |
Herbel BK et al. | Safflower oil consumption does not increase plasma conjugated linoleic acid concentrations in humans. | 1998 | Am. J. Clin. Nutr. | pmid:9459383 |