| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Uterine Cervical Neoplasms | D002583 | 10 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Diabetic Ketoacidosis | D016883 | 16 associated lipids |
| Otitis Externa | D010032 | 8 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Hepatolenticular Degeneration | D006527 | 3 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Boles DJ and Rizzo WB | Dietary fatty acids temporarily alter liver very long-chain fatty acid composition in mice. | 1992 | J. Nutr. | pmid:1640260 |
| Mensink RP et al. | Effect of dietary cis and trans fatty acids on serum lipoprotein[a] levels in humans. | 1992 | J. Lipid Res. | pmid:1431574 |
| Kilsdonk EP et al. | Effect of phospholipid fatty acid composition of endothelial cells on cholesterol efflux rates. | 1992 | J. Lipid Res. | pmid:1402404 |
| Kelley RI | Beta-oxidation of long-chain fatty acids by human fibroblasts: evidence for a novel long-chain acyl-coenzyme A dehydrogenase. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1540149 |
| Britton M et al. | Diet as a source of phospholipid esterified 9,11-octadecadienoic acid in humans. | 1992 | Clin. Sci. | pmid:1325328 |
| Jannace PW et al. | Effects of oral soy phosphatidylcholine on phagocytosis, arachidonate concentrations, and killing by human polymorphonuclear leukocytes. | 1992 | Am. J. Clin. Nutr. | pmid:1323926 |
| Winterbourn CC et al. | Chlorohydrin formation from unsaturated fatty acids reacted with hypochlorous acid. | 1992 | Arch. Biochem. Biophys. | pmid:1321589 |
| Sauer LA and Dauchy RT | Uptake of plasma lipids by tissue-isolated hepatomas 7288CTC and 7777 in vivo. | 1992 | Br. J. Cancer | pmid:1503901 |
| Garg ML et al. | Desaturation of linoleic acid in the small bowel is increased by short-term fasting and by dietary content of linoleic acid. | 1992 | Biochim. Biophys. Acta | pmid:1606171 |
| Rioux FM and Innis SM | Arachidonic acid concentrations in plasma and liver phospholipid and cholesterol esters of piglets raised on formulas with different linoleic and linolenic acid contents. | 1992 | Am. J. Clin. Nutr. | pmid:1609747 |
| Kannan R et al. | Anorexic contribution to increased linoleate mobilization and oxidation in lymphoma-bearing mice. | 1992 | Lipids | pmid:1579055 |
| Kawashima Y et al. | Reduction by clofibric acid of serum arachidonic acid in rats. Effect on the acyl composition of renal phospholipids. | 1992 | Biochem. Pharmacol. | pmid:1610396 |
| Uden S et al. | Antioxidant therapy for recurrent pancreatitis: biochemical profiles in a placebo-controlled trial. | 1992 | Aliment. Pharmacol. Ther. | pmid:1600043 |
| Di Mascio P et al. | Are dioxetanes chemiluminescent intermediates in lipoperoxidation? | 1992 | Free Radic. Biol. Med. | pmid:1601322 |
| Bonanome A et al. | Effect of dietary monounsaturated and polyunsaturated fatty acids on the susceptibility of plasma low density lipoproteins to oxidative modification. | 1992 | Arterioscler. Thromb. | pmid:1558840 |
| Iio M and Barnes DW | Death of serum-free mouse embryo cells caused by transforming growth factor beta 1 and effects of nutritional factors. | 1992 | Cytotechnology | pmid:1369213 |
| Or R et al. | Essential fatty acids and iron are involved at distinct stages of the proliferative cycle but not in the activation of human T cells. | 1992 | Clin. Immunol. Immunopathol. | pmid:1371729 |
| Pavero C et al. | Administration modalities and intestinal lymph absorption of arachidonic acid in rats. | 1992 | J. Nutr. | pmid:1640261 |
| Leaf AA et al. | Factors affecting long-chain polyunsaturated fatty acid composition of plasma choline phosphoglycerides in preterm infants. | 1992 | J. Pediatr. Gastroenterol. Nutr. | pmid:1535657 |
| Glasgow WC et al. | Modulation of the epidermal growth factor mitogenic response by metabolites of linoleic and arachidonic acid in Syrian hamster embryo fibroblasts. Differential effects in tumor suppressor gene (+) and (-) phenotypes. | 1992 | J. Biol. Chem. | pmid:1587852 |
| Kalyanaraman B et al. | Synergistic interaction between the probucol phenoxyl radical and ascorbic acid in inhibiting the oxidation of low density lipoprotein. | 1992 | J. Biol. Chem. | pmid:1313022 |
| Byczkowski JZ and Kulkarni AP | Vanadium redox cycling, lipid peroxidation and co-oxygenation of benzo(a)pyrene-7,8-dihydrodiol. | 1992 | Biochim. Biophys. Acta | pmid:1315157 |
| Matsumoto M et al. | D-galactosamine-induced cell damage enhances specific binding of prostaglandin E1 to rat hepatocytes. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1315527 |
| Huang SC et al. | Dietary fat influences Ia antigen expression and immune cell populations in the murine peritoneum and spleen. | 1992 | J. Nutr. | pmid:1316956 |
| Garfinkel M et al. | Insulinotropic potency of lauric acid: a metabolic rationale for medium chain fatty acids (MCF) in TPN formulation. | 1992 | J. Surg. Res. | pmid:1593871 |
| Kang JX et al. | The chloride channel blocker anthracene 9-carboxylate inhibits fatty acid incorporation into phospholipid in cultured human airway epithelial cells. | 1992 | Biochem. J. | pmid:1323271 |
| Howie A et al. | Effects of cholesterol on viability and (n - 6) fatty acid metabolism in cultured human monocyte-like cells (U937). | 1992 | Biochem. Cell Biol. | pmid:1335730 |
| Zöllner N and Tatò F | Fatty acid composition of the diet: impact on serum lipids and atherosclerosis. | 1992 | Clin Investig | pmid:1472837 |
| Nishioka T et al. | [Studies on the influence of long-term doses of lipid peroxide generators on rat pancreas]. | 1992 | Nihon Shokakibyo Gakkai Zasshi | pmid:1404992 |
| Spitz DR et al. | The effect of monosaturated and polyunsaturated fatty acids on oxygen toxicity in cultured cells. | 1992 | Pediatr. Res. | pmid:1408477 |
| Vilchez C et al. | Research note: eggshell quality in Japanese quail fed different fatty acids. | 1992 | Poult. Sci. | pmid:1409241 |
| Shao Z and Mitra AK | Nasal membrane and intracellular protein and enzyme release by bile salts and bile salt-fatty acid mixed micelles: correlation with facilitated drug transport. | 1992 | Pharm. Res. | pmid:1409402 |
| Byczkowski JZ and Kulkarni AP | Linoleate-dependent co-oxygenation of benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol by rat cytosolic lipoxygenase. | 1992 | Xenobiotica | pmid:1413876 |
| Mori S et al. | Enzymatic properties of polyethylene glycol-modified cholesterol esterase in organic solvents. | 1992 | Biotechnol. Appl. Biochem. | pmid:1418688 |
| Wang PF and Zheng RL | Inhibitions of the autoxidation of linoleic acid by flavonoids in micelles. | 1992 | Chem. Phys. Lipids | pmid:1486658 |
| Huang YS et al. | Effect of dietary linoleic acid content on the distribution of triacylglycerol molecular species in rat adipose tissue. | 1992 | Lipids | pmid:1487970 |
| Koba K et al. | Effects of alpha-tocopherol and tocotrienols on blood pressure and linoleic acid metabolism in the spontaneously hypertensive rat (SHR). | 1992 | Biosci. Biotechnol. Biochem. | pmid:1368948 |
| Chen HW et al. | Gender and dietary fat affect alpha-tocopherol status in F344/N rats. | 1992 | Lipids | pmid:1491600 |
| Farrington M et al. | Resistance to desiccation and skin fatty acids in outbreak strains of methicillin-resistant Staphylococcus aureus. | 1992 | J. Med. Microbiol. | pmid:1731060 |
| Fischer SM et al. | The effect of dietary fat on the rapid development of mammary tumors induced by 7,12-dimethylbenz(a)anthracene in SENCAR mice. | 1992 | Cancer Res. | pmid:1732055 |
| Aw TY et al. | Absorption and lymphatic transport of peroxidized lipids by rat small intestine in vivo: role of mucosal GSH. | 1992 | Am. J. Physiol. | pmid:1733274 |
| Opara EC et al. | Characterization of the insulinotropic potency of polyunsaturated fatty acids. | 1992 | Endocrinology | pmid:1733714 |
| Duthie GG et al. | Lipid peroxidation, antioxidant concentrations, and fatty acid contents of muscle tissue from malignant hyperthermia-susceptible swine. | 1992 | Arch. Biochem. Biophys. | pmid:1632646 |
| Yin D et al. | Fenton reagents may not initiate lipid peroxidation in an emulsified linoleic acid model system. | 1992 | Free Radic. Biol. Med. | pmid:1459478 |
| Fotouhi N and Jenkins TC | Ruminal biohydrogenation of linoleoyl methionine and calcium linoleate in sheep. | 1992 | J. Anim. Sci. | pmid:1459921 |
| Henderson WR and Chi EY | Cytotoxic activity of 13-hydroxyoctadecadienoic acid against Toxoplasma gondii. | 1992 | Parasitology | pmid:1461675 |
| Williams LL et al. | Quantitative association between altered plasma esterified omega-6 fatty acid proportions and psychological stress. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1461929 |
| Zu HX and Schut HA | Inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline-DNA adduct formation in CDF1 mice by heat-altered derivatives of linoleic acid. | 1992 | Food Chem. Toxicol. | pmid:1544610 |
| Derian CK and Lewis DF | Activation of 15-lipoxygenase by low density lipoprotein in vascular endothelial cells. Relationship to the oxidative modification of low density lipoprotein. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1546066 |
| Dullaart RP et al. | Long-term effects of linoleic-acid-enriched diet on albuminuria and lipid levels in type 1 (insulin-dependent) diabetic patients with elevated urinary albumin excretion. | 1992 | Diabetologia | pmid:1547922 |
| Connolly JM and Rose DP | Interactions between epidermal growth factor-mediated autocrine regulation and linoleic acid-stimulated growth of a human prostate cancer cell line. | 1992 | Prostate | pmid:1549552 |
| Mori TA et al. | Differential effect of aspirin on platelet aggregation in IDDM. | 1992 | Diabetes | pmid:1551486 |
| Homa ST and Brown CA | Changes in linoleic acid during follicular development and inhibition of spontaneous breakdown of germinal vesicles in cumulus-free bovine oocytes. | 1992 | J. Reprod. Fertil. | pmid:1552477 |
| Doderer A et al. | Purification and characterization of two lipoxygenase isoenzymes from germinating barley. | 1992 | Biochim. Biophys. Acta | pmid:1554746 |
| Naidu MR et al. | Intratumoral gamma-linoleic acid therapy of human gliomas. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1589443 |
| Bell JG et al. | Effects of increasing dietary linoleic acid on phospholipid fatty acid composition and eicosanoid production in leucocytes and gill cells of Atlantic salmon (Salmo salar). | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1589446 |
| Keler T et al. | Specific growth stimulation by linoleic acid in hepatoma cell lines transfected with the target protein of a liver carcinogen. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1594582 |
| Iwamoto KS et al. | Linoleate produces remission in canine mycosis fungoides. | 1992 | Cancer Lett. | pmid:1596872 |
| Dwight JF et al. | Membrane incorporation of non-esterified fatty acids and effects on the sodium pump of human erythrocytes. | 1992 | Clin. Sci. | pmid:1310925 |
| Ziylan ZY et al. | Effect of dietary n-3 fatty acid deficiency on blood-to-brain transfer of sucrose, alpha-aminoisobutyric acid and phenylalanine in the rat. | 1992 | Neurosci. Lett. | pmid:1625821 |
| Collier A et al. | Free radical activity and hemostatic factors in NIDDM patients with and without microalbuminuria. | 1992 | Diabetes | pmid:1628764 |
| Thorisson S et al. | Some oxidation products of ethoxyquin including those found in autoxidising systems. | 1992 Jan-Feb | Chem. Phys. Lipids | pmid:1505065 |
| Lokesh B et al. | Effect of different dietary triglycerides on liver fatty acids and prostaglandin synthesis by mouse peritoneal cells. | 1992 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:1640628 |
| Clouva-Molyvdas P et al. | Short-term dietary lipid manipulation does not affect survival in two models of murine sepsis. | 1992 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:1640632 |
| Pirozhkov SV et al. | Effect of chronic consumption of ethanol and vitamin E on fatty acid composition and lipid peroxidation in rat heart tissue. | 1992 Jul-Aug | Alcohol | pmid:1637499 |
| Terracina L et al. | Linoleic acid metabolism in brain cortex of aged rats. | 1992 Jul-Aug | Ital. J. Biochem. | pmid:1428781 |
| Cabré E et al. | Plasma polyunsaturated fatty acids in liver cirrhosis with or without chronic hepatic encephalopathy: a preliminary study. | 1992 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:1386392 |
| Diboune M et al. | Composition of phospholipid fatty acids in red blood cell membranes of patients in intensive care units: effects of different intakes of soybean oil, medium-chain triglycerides, and black-currant seed oil. | 1992 Mar-Apr | JPEN J Parenter Enteral Nutr | pmid:1556808 |
| Shultz TD et al. | Differential stimulatory and inhibitory responses of human MCF-7 breast cancer cells to linoleic acid and conjugated linoleic acid in culture. | 1992 Nov-Dec | Anticancer Res. | pmid:1295460 |
| GarcÃa de Lorenzo A and Culebras JM | [Linoleic acid and the immune system. Controversies about lipid emulsions]. | 1992 Nov-Dec | Nutr Hosp | pmid:1477148 |
| Ramesh G et al. | Effect of essential fatty acids on tumor cells. | 1992 Sep-Oct | Nutrition | pmid:1330107 |
| Giron MD et al. | Long-term effects of dietary monounsaturated and polyunsaturated fatty acids on plasma lipids in dogs. | 1992 Sep-Oct | Arch Int Physiol Biochim Biophys | pmid:1282382 |
| Chopra M et al. | Free radical scavenging of lutein in vitro. | 1993 | Ann. N. Y. Acad. Sci. | pmid:8129303 |
| Viscardi RM and Max SR | Unsaturated fatty acid modulation of glucocorticoid receptor binding in L2 cells. | 1993 | Steroids | pmid:8212085 |
| Lomnitski L et al. | The interaction between beta-carotene and lipoxygenase in plant and animal systems. | 1993 | Biochim. Biophys. Acta | pmid:8481396 |
| Dutta-Roy AK et al. | Purification and characterization of fatty acid-binding proteins from brown adipose tissue of the rat. | 1993 | Biochim. Biophys. Acta | pmid:8334153 |
| Shichiri G et al. | Polyunsaturated fatty acid metabolism and acetylated low density lipoprotein uptake in J774A.1 cells. | 1993 | Arch. Biochem. Biophys. | pmid:8099780 |
| Leichsenring M et al. | Scaly skin alterations and plasma fatty acids in Congolese children. | 1993 | Acta Trop. | pmid:7902652 |
| Hernell O et al. | Does the bile salt-stimulated lipase of human milk have a role in the use of the milk long-chain polyunsaturated fatty acids? | 1993 | J. Pediatr. Gastroenterol. Nutr. | pmid:8315552 |
| Hatala MA et al. | Characterization of phospholipase A2 activity in MDA-MB-435 human breast cancer cells. | 1993 | Cancer Lett. | pmid:8402571 |
| Rose DP et al. | Effect of diets containing different levels of linoleic acid on human breast cancer growth and lung metastasis in nude mice. | 1993 | Cancer Res. | pmid:8402646 |
| Wey HE et al. | Essential fatty acid deficiency in cultured human keratinocytes attenuates toxicity due to lipid peroxidation. | 1993 | Toxicol. Appl. Pharmacol. | pmid:8511784 |
| Thompson RL et al. | Cigarette smoking, polyunsaturated fats, and coronary heart disease. | 1993 | Ann. N. Y. Acad. Sci. | pmid:8512244 |
| Rich MR | Conformational analysis of arachidonic and related fatty acids using molecular dynamics simulations. | 1993 | Biochim. Biophys. Acta | pmid:8329458 |
| Richter G and Lemser A | [The use of native triticale in poultry. 3. Use in laying hens]. | 1993 | Arch Tierernahr | pmid:8517768 |
| Hudson EA et al. | Kinetics of the inhibition of tumour growth in mice by eicosapentaenoic acid-reversal by linoleic acid. | 1993 | Biochem. Pharmacol. | pmid:8517859 |
| de Deckere EA et al. | Hepatic de novo fatty acid synthesis in the rat. | 1993 | Ann. Nutr. Metab. | pmid:8215236 |
| Jakobsen K et al. | The biological activity of natural source tocopherols in chickens fed fresh or oxidized fat rich in linoleic acid. | 1993 | Arch Tierernahr | pmid:8215903 |
| Spiteller G | Review: on the chemistry of oxidative stress. | 1993 | J Lipid Mediat | pmid:8219002 |
| Oulhaj H et al. | Synthesis and distribution of rat Sertoli cell proteoglycans are modulated by linoleate and vitamin E. | 1993 | Biochem. Mol. Biol. Int. | pmid:8275018 |
| Bronstein JC and Bull AW | The correlation between 13-hydroxyoctadecadienoate dehydrogenase (13-HODE dehydrogenase) and intestinal cell differentiation. | 1993 | Prostaglandins | pmid:8278616 |
| Saito M and Yamaguchi M | Response of liver microsomal mixed-function oxidases to dietary linoleic acid levels in rats. | 1993 | J. Nutr. Sci. Vitaminol. | pmid:8283320 |
| Roy SK et al. | Lipoxygenase activity in rat embryos and its potential for xenobiotic oxidation. | 1993 | Biol. Neonate | pmid:8353158 |
| Buchanan MR and Brister SJ | Altering vessel wall fatty acid metabolism: a new strategy for antithrombotic treatment. | 1993 | Semin. Thromb. Hemost. | pmid:8356461 |
| Zheng RL et al. | Inhibition of the autoxidation of linoleic acid by phenylpropanoid glycosides from Pedicularis in micelles. | 1993 | Chem. Phys. Lipids | pmid:8358852 |
| Davis PA et al. | A linoleate-enriched cheese product reduces low-density lipoprotein in moderately hypercholesterolemic adults. | 1993 | Ann. Intern. Med. | pmid:8363165 |
| Reaven P et al. | Effects of oleate-rich and linoleate-rich diets on the susceptibility of low density lipoprotein to oxidative modification in mildly hypercholesterolemic subjects. | 1993 | J. Clin. Invest. | pmid:8432867 |
| Abbey M et al. | Oxidation of low-density lipoproteins: intraindividual variability and the effect of dietary linoleate supplementation. | 1993 | Am. J. Clin. Nutr. | pmid:8438773 |
| Jones AL et al. | Temperature-induced membrane-lipid adaptation in Acanthamoeba castellanii. | 1993 | Biochem. J. | pmid:8439295 |
| Terada N et al. | Definition of the roles for iron and essential fatty acids in cell cycle progression of normal human T lymphocytes. | 1993 | Exp. Cell Res. | pmid:8440323 |