Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Uterine Cervical Neoplasms D002583 10 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Breast Neoplasms D001943 24 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lung Neoplasms D008175 171 associated lipids
Hepatolenticular Degeneration D006527 3 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Monfregola L et al. Physical and water sorption properties of chemically modified pectin with an environmentally friendly process. 2011 Biomacromolecules pmid:21553919
Shin D et al. Dietary combination effects of conjugated linoleic acid and flaxseed or fish oil on the concentration of linoleic and arachidonic acid in poultry meat. 2011 Poult. Sci. pmid:21597077
Yepuri G et al. Dietary modulation of body composition and insulin sensitivity during catch-up growth in rats: effects of oils rich in n-6 or n-3 PUFA. 2011 Br. J. Nutr. pmid:21281526
Lee MJ et al. The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia. 2011 Mol. Cells pmid:21331775
Cunnane SC and Guesnet P Linoleic acid recommendations--A house of cards. 2011 Prostaglandins Leukot. Essent. Fatty Acids pmid:21963263
P Wrobel T et al. Imaging of lipids in atherosclerotic lesion in aorta from ApoE/LDLR-/- mice by FT-IR spectroscopy and Hierarchical Cluster Analysis. 2011 Analyst pmid:22007352
Banta JP et al. Effects of prepartum supplementation of linoleic and mid-oleic sunflower seed on cow performance, cow reproduction, and calf performance from birth through slaughter, and effects on intake and digestion in steers. 2011 J. Anim. Sci. pmid:21788431
Končić MZ et al. Antiradical, chelating and antioxidant activities of hydroxamic acids and hydroxyureas. 2011 Molecules pmid:21788931
Arciniega JC et al. Effects of free fatty acids on meibomian lipid films. 2011 Exp. Eye Res. pmid:21718696
Yang Y et al. Synthesis and antioxidant capacities of hydroxyl derivatives of cinnamoylphenethylamine in protecting DNA and scavenging radicals. 2011 Free Radic. Res. pmid:21128731
Rakib MA et al. Preventive effect of t,t-conjugated linoleic acid on 12-O-tetradecanoylphorbol-13-acetate-induced inhibition of gap junctional intercellular communication in human mammary epithelial MCF-10A cells. 2011 J. Agric. Food Chem. pmid:21391601
Tuei VC et al. Effects of human serum albumin complexed with free fatty acids on cell viability and insulin secretion in the hamster pancreatic β-cell line HIT-T15. 2011 Life Sci. pmid:21396379
Mihaljević B et al. Linoleic acid peroxidation vs. isomerization: a biomimetic model of free radical reactivity in the presence of thiols. 2011 Org. Biomol. Chem. pmid:21442126
Turk HF et al. Linoleic acid and butyrate synergize to increase Bcl-2 levels in colonocytes. 2011 Int. J. Cancer pmid:20232381
McCusker MM and Grant-Kels JM Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids. 2010 Jul-Aug Clin. Dermatol. pmid:20620762
NaÄ­dina VP et al. [Changes in lipid composition of human plasma and erythrocyte membranes due to sodium hydroxybutyrate and normobaric hyperoxia during bed rest]. 2010 Jan-Feb Aviakosm Ekolog Med pmid:20804001
Zovko Koncić M et al. Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat. 2010 Aug-Sep Food Chem. Toxicol. pmid:20488218
Hajlaoui H et al. Chemical composition and biological activities of Tunisian Cuminum cyminum L. essential oil: a high effectiveness against Vibrio spp. strains. 2010 Aug-Sep Food Chem. Toxicol. pmid:20488223
Jung S et al. Effect of dietary mixture of gallic acid and linoleic acid on antioxidative potential and quality of breast meat from broilers. 2010 Meat Sci. pmid:20609528
Feldstein AE et al. Mass spectrometric profiling of oxidized lipid products in human nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. 2010 J. Lipid Res. pmid:20631297
Wang L et al. [Effects of linoleic acid on intracellular calcium concentration in primarily cultured rat pancreatic β-cells and underlying mechanism]. 2010 Sheng Li Xue Bao pmid:21170499
Khiaosa-ard R et al. Methods of emulsifying linoleic acid in biohydrogenation studies in vitro may bias the resulting fatty acid profiles. 2010 Lipids pmid:20582723
Delhanty PJ et al. Unsaturated fatty acids prevent desensitization of the human growth hormone secretagogue receptor by blocking its internalization. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20587751
Ross RA et al. Differential effects of hypothalamic long-chain fatty acid infusions on suppression of hepatic glucose production. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20647558
Ohmori H et al. Dietary linoleic acid and glucose enhances azoxymethane-induced colon cancer and metastases via the expression of high-mobility group box 1. 2010 Pathobiology pmid:20616616
Gao F et al. Quantifying conversion of linoleic to arachidonic and other n-6 polyunsaturated fatty acids in unanesthetized rats. 2010 J. Lipid Res. pmid:20622136
Herdmann A et al. Effect of dietary n-3 and n-6 PUFA on lipid composition of different tissues of German Holstein bulls and the fate of bioactive fatty acids during processing. 2010 J. Agric. Food Chem. pmid:20597504
Zaman MM et al. Linoleic acid supplementation results in increased arachidonic acid and eicosanoid production in CF airway cells and in cftr-/- transgenic mice. 2010 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:20656894
Frangioudakis G et al. Saturated- and n-6 polyunsaturated-fat diets each induce ceramide accumulation in mouse skeletal muscle: reversal and improvement of glucose tolerance by lipid metabolism inhibitors. 2010 Endocrinology pmid:20660065
Beezhold BL et al. Vegetarian diets are associated with healthy mood states: a cross-sectional study in seventh day adventist adults. 2010 Nutr J pmid:20515497
Brito GA et al. Lymphocytes transfer [(14)C]-labeled fatty acids to skeletal muscle in culture; modulation by exercise. 2010 Cell Biochem. Funct. pmid:20517891
Li TL et al. [Study on the chemical constituents of Humulus scandens]. 2010 Zhong Yao Cai pmid:20518305
Livraghi S et al. Decreasing the oxidative potential of TiO(2) nanoparticles through modification of the surface with carbon: a new strategy for the production of safe UV filters. 2010 Chem. Commun. (Camb.) pmid:20938530
Biro A et al. Complement protein C1q recognizes enzymatically modified low-density lipoprotein through unesterified fatty acids generated by cholesterol esterase. 2010 Biochemistry pmid:20166680
Maia MR et al. Toxicity of unsaturated fatty acids to the biohydrogenating ruminal bacterium, Butyrivibrio fibrisolvens. 2010 BMC Microbiol. pmid:20167098
Sarikurkcu C et al. Evaluation of metal concentration and antioxidant activity of three edible mushrooms from Mugla, Turkey. 2010 Food Chem. Toxicol. pmid:20167240
Vukovic N et al. An efficient synthesis and antioxidant properties of novel imino and amino derivatives of 4-hydroxy coumarins. 2010 Arch. Pharm. Res. pmid:20191339
Hirai S et al. Loss of sense transgene-induced post-transcriptional gene silencing by sequential introduction of the same transgene sequences in tobacco. 2010 FEBS J. pmid:20180844
Pauloin A et al. Oleate and linoleate stimulate degradation of β-casein in prolactin-treated HC11 mouse mammary epithelial cells. 2010 Cell Tissue Res. pmid:20182891
Gammill W et al. Comparative study of high-linoleic acid vegetable oils for the production of conjugated linoleic acid. 2010 J. Agric. Food Chem. pmid:20136082
Harris W Omega-6 and omega-3 fatty acids: partners in prevention. 2010 Curr Opin Clin Nutr Metab Care pmid:20145438
Goebel AS et al. Dermal targeting using colloidal carrier systems with linoleic acid. 2010 Eur J Pharm Biopharm pmid:20170728
Thornhill JA et al. Pathways for the influx of molecules into cercariae of Schistosoma mansoni during skin penetration. 2010 Parasitology pmid:20128942
Dailey MJ et al. Nutrient specific feeding and endocrine effects of jejunal infusions. 2010 Obesity (Silver Spring) pmid:20134410
Combet E et al. Development of an in vitro system combining aqueous and lipid phases as a tool to understand gastric nitrosation. 2010 Rapid Commun. Mass Spectrom. pmid:20112267
Castellanos P et al. Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution. 2010 Reprod. Toxicol. pmid:20096347
Coyral-Castel S et al. Effects of unsaturated fatty acids on progesterone secretion and selected protein kinases in goat granulosa cells. 2010 Domest. Anim. Endocrinol. pmid:20097509
Nakamura T et al. Excessive fat restriction might promote the recurrence of colorectal tumors. 2010 Nutr Cancer pmid:20099189
Beevi SS et al. Polyphenolics profile, antioxidant and radical scavenging activity of leaves and stem of Raphanus sativus L. 2010 Plant Foods Hum Nutr pmid:20072818
Edwards SJ et al. Impact of distal mutation on hydrogen transfer interface and substrate conformation in soybean lipoxygenase. 2010 J Phys Chem B pmid:20423074
Patwardhan AM et al. Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents. 2010 J. Clin. Invest. pmid:20424317
Brown DA and Passmore GM Some new insights into the molecular mechanisms of pain perception. 2010 J. Clin. Invest. pmid:20424321
Even P et al. Postprandial effects of a lipid-rich meal in the rat are modulated by the degree of unsaturation of 18C fatty acids. 2010 Metab. Clin. Exp. pmid:19775712
Renaville B et al. Plasma and follicular fluid fatty acid profiles in dairy cows. 2010 Reprod. Domest. Anim. pmid:19055554
Kubala L et al. Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation. 2010 Free Radic. Biol. Med. pmid:20156554
Gholivand MB et al. Chemical composition and antioxidant activities of the essential oil and methanol extracts of Psammogeton canescens. 2010 Food Chem. Toxicol. pmid:19748545
Kim BS et al. Effect of surfactant on the production of oxygenated unsaturated fatty acids by Bacillus megaterium ALA2. 2010 N Biotechnol pmid:19748603
Joshi SC et al. Antioxidant and antibacterial activities of the leaf essential oils of Himalayan Lauraceae species. 2010 Food Chem. Toxicol. pmid:19766161
Lábaque MC et al. Effect of age and body weight of Greater Rhea (Rhea americana) females on egg number, size and composition. 2010 Br. Poult. Sci. pmid:21161792
Zidi A et al. Pleiotropic effects of the goat prolactin receptor genotype on milk fatty acid composition. 2010 Domest. Anim. Endocrinol. pmid:20399061
Peoples GE and McLennan PL Dietary fish oil reduces skeletal muscle oxygen consumption, provides fatigue resistance and improves contractile recovery in the rat in vivo hindlimb. 2010 Br. J. Nutr. pmid:20691135
Deiana M et al. Protective effect of simple phenols from extravirgin olive oil against lipid peroxidation in intestinal Caco-2 cells. 2010 Food Chem. Toxicol. pmid:20691238
Köse EO et al. Chemical composition, antimicrobial and antioxidant activities of the essential oils of Sideritis erythrantha Boiss. and Heldr. (var. erythrantha and var. cedretorum P.H. Davis) endemic in Turkey. 2010 Food Chem. Toxicol. pmid:20670669
Strandvik B Fatty acid metabolism in cystic fibrosis. 2010 Prostaglandins Leukot. Essent. Fatty Acids pmid:20673710
Rodrigues HG et al. Dietary free oleic and linoleic acid enhances neutrophil function and modulates the inflammatory response in rats. 2010 Lipids pmid:20730605
Tel G et al. Chemical composition of the essential oil and hexane extract of Salvia chionantha and their antioxidant and anticholinesterase activities. 2010 Food Chem. Toxicol. pmid:20732375
Takahashi S et al. The occurrence of renin inhibitor in rice: isolation, identification, and structure-function relationship. 2010 Biosci. Biotechnol. Biochem. pmid:20699562
Vij N Linoleic acid supplement in cystic fibrosis: friend or foe? 2010 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:20709729
Aziz AA et al. Increasing Dietary alpha-linolenic acid enhances tissue levels of long-chain n-3 PUFA when linoleic acid intake is low in hamsters. 2010 Ann. Nutr. Metab. pmid:20714137
Gutiérrez-Correa J Trypanosoma cruzi dihydrolipoamide dehydrogenase as target of reactive metabolites generated by cytochrome c/hydrogen peroxide (or linoleic acid hydroperoxide)/phenol systems. 2010 Free Radic. Res. pmid:20815787
Serhan Z et al. Complete determination of natural site-specific enantio-isotopomeric excesses in linoleic acid using natural abundance deuterium 2D NMR in polypeptide mesophases. 2010 Chem. Commun. (Camb.) pmid:20721385
Noel JT et al. Specific responses of Salmonella enterica to tomato varieties and fruit ripeness identified by in vivo expression technology. 2010 PLoS ONE pmid:20824208
Macouzet M et al. Genetic and structural comparison of linoleate isomerases from selected food-grade bacteria. 2010 J. Appl. Microbiol. pmid:20825518
Collin F et al. Experimental evidence of the reciprocal oxidation of Bovine Serum Albumin and Linoleate in aqueous solution, initiated by HO* free radicals. 2010 Biochimie pmid:20685376
Bolton B and Halpern BP Orthonasal and retronasal but not oral-cavity-only discrimination of vapor-phase fatty acids. 2010 Chem. Senses pmid:20100787
Guo JJ and Hu CH Mechanism of chain termination in lipid peroxidation by carotenes: a theoretical study. 2010 J Phys Chem B pmid:21105679
Wu TC et al. Fatty acid composition of Taiwanese human milk. 2010 J Chin Med Assoc pmid:21093826
Panagiotakos DB et al. Fatty acids intake and depressive symptomatology in a Greek sample: an epidemiological analysis. 2010 J Am Coll Nutr pmid:21677122
West SG et al. Effects of diets high in walnuts and flax oil on hemodynamic responses to stress and vascular endothelial function. 2010 J Am Coll Nutr pmid:21677123
Demir AS and Talpur FN Chemoenzymatic conversion of linoleic acid into conjugated linoleic acid. 2010 J. Agric. Food Chem. pmid:20058923
Duckett SK and Gillis MH Effects of oil source and fish oil addition on ruminal biohydrogenation of fatty acids and conjugated linoleic acid formation in beef steers fed finishing diets. 2010 J. Anim. Sci. pmid:20348369
Aluf Y et al. Specific oxidative stress profile associated with partial striatal dopaminergic depletion by 6-hydroxydopamine as assessed by a novel multifunctional marker molecule. 2010 Free Radic. Res. pmid:20370558
Tume RK et al. Enriching M. sternomandibularis with alpha-tocopherol by dietary means does not protect against the lipid oxidation caused by high-pressure processing. 2010 Meat Sci. pmid:20374755
Berthelot V et al. Utilization of extruded linseed to modify fatty composition of intensively-reared lamb meat: effect of associated cereals (wheat vs. corn) and linoleic acid content of the diet. 2010 Meat Sci. pmid:20374762
Della Casa G et al. Performance and fat quality of heavy pigs fed maize differing in linoleic acid content. 2010 Meat Sci. pmid:20374768
Aldai N et al. Double-muscling character influences the trans-18:1 and conjugated linoleic acid profiles in concentrate-fed yearling bulls. 2010 Meat Sci. pmid:20374865
Chen T et al. Analytical characterization of Hempseed (seed of Cannabis sativa L.) oil from eight regions in China. 2010 J Diet Suppl pmid:22435611
Litvinov D et al. Anti-atherosclerotic actions of azelaic acid, an end product of linoleic acid peroxidation, in mice. 2010 Atherosclerosis pmid:19880116
Wan ZX et al. Lipid content and fatty acids composition of mature human milk in rural North China. 2010 Br. J. Nutr. pmid:19825220
Li Z et al. Dual response surface-optimized synthesis of L-menthyl conjugated linoleate in solvent-free system by Candida rugosa lipase. 2010 Bioresour. Technol. pmid:19833506
Friesen RW and Innis SM Linoleic acid is associated with lower long-chain n-6 and n-3 fatty acids in red blood cell lipids of Canadian pregnant women. 2010 Am. J. Clin. Nutr. pmid:19923368
Runyon JB et al. Parasitism by Cuscuta pentagona sequentially induces JA and SA defence pathways in tomato. 2010 Plant Cell Environ. pmid:19930126
Schwartz J et al. Dietary intake and plasma concentrations of PUFA and LC-PUFA in breastfed and formula fed infants under real-life conditions. 2010 Eur J Nutr pmid:19851802
Brodhun F et al. PpoC from Aspergillus nidulans is a fusion protein with only one active haem. 2010 Biochem. J. pmid:19878096
Khiaosa-Ard R et al. Transfer of linoleic and linolenic acid from feed to milk in cows fed isoenergetic diets differing in proportion and origin of concentrates and roughages. 2010 J. Dairy Res. pmid:20482940
Salehipour M et al. Polyunsaturated fatty acids and modulation of cholesterol homeostasis in THP-1 macrophage-derived foam cells. 2010 Int J Mol Sci pmid:21151462
Alloatti A et al. Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. 2010 PLoS ONE pmid:21151902
Zabielski P et al. The effect of high-fat diet on the sphingolipid pathway of signal transduction in regenerating rat liver. 2010 Prostaglandins Other Lipid Mediat. pmid:20599517
Zengin G et al. In vitro antioxidant capacities and fatty acid compositions of three Centaurea species collected from Central Anatolia region of Turkey. 2010 Food Chem. Toxicol. pmid:20600531
Shen Q et al. Antioxidant activity in vitro of the selenium-contained protein from the Se-enriched Bifidobacterium animalis 01. 2010 Anaerobe pmid:20601030