Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Child Nutrition Disorders D015362 1 associated lipids
Refeeding Syndrome D055677 1 associated lipids
Pellagra D010383 1 associated lipids
Carcinoma, Krebs 2 D002287 1 associated lipids
Refractive Errors D012030 1 associated lipids
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
Malaria, Cerebral D016779 1 associated lipids
Onchocerciasis D009855 1 associated lipids
Liposarcoma D008080 1 associated lipids
Gastroschisis D020139 1 associated lipids
Fat Necrosis D005218 1 associated lipids
Facial Nerve Diseases D005155 1 associated lipids
Aneurysm D000783 2 associated lipids
Circoviridae Infections D018173 2 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Lymphopenia D008231 2 associated lipids
Leptospirosis D007922 2 associated lipids
Lactose Intolerance D007787 2 associated lipids
Disease D004194 2 associated lipids
Hypokinesia D018476 2 associated lipids
Darier Disease D007644 2 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Dermatitis, Toxicodendron D011040 3 associated lipids
Hepatolenticular Degeneration D006527 3 associated lipids
Infertility D007246 3 associated lipids
Wasting Syndrome D019282 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Dermatitis, Phototoxic D017484 4 associated lipids
Varicocele D014646 4 associated lipids
Biliary Atresia D001656 4 associated lipids
Cicatrix, Hypertrophic D017439 4 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Varicose Ulcer D014647 4 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Melanosis D008548 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Tinea Versicolor D014010 5 associated lipids
Meningeal Neoplasms D008577 5 associated lipids
Choroidal Neovascularization D020256 5 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Mucositis D052016 7 associated lipids
Nausea D009325 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Sanderson P et al. Dietary fish oil diminishes the antigen presentation activity of rat dendritic cells. 1997 Biochem. Soc. Trans. pmid:9191396
Peres CM et al. Transference of fatty acids from macrophages to lymphocytes in culture. 1997 Biochem. Soc. Trans. pmid:9191389
Berry H et al. Excess substrate inhibition of soybean lipoxygenase-1 is mainly oxygen-dependent. 1997 FEBS Lett. pmid:9188786
Ek BA et al. Fatty acid binding proteins reduce 15-lipoxygenase-induced oxygenation of linoleic acid and arachidonic acid. 1997 Biochim. Biophys. Acta pmid:9187305
Memoli S et al. Diffusible melanin-related metabolites are potent inhibitors of lipid peroxidation. 1997 Biochim. Biophys. Acta pmid:9187303
Banfi C et al. Linoleic acid enhances the secretion of plasminogen activator inhibitor type 1 by HepG2 cells. 1997 J. Lipid Res. pmid:9186904
Ding ST and Lilburn MS Changes in fatty acid profiles in different lipid classes during late development of turkey embryos from two genetic lines. 1997 Poult. Sci. pmid:9181615
Hornstra G and Kester AD Effect of the dietary fat type on arterial thrombosis tendency: systematic studies with a rat model. 1997 Atherosclerosis pmid:9180241
Harvei S et al. Prediagnostic level of fatty acids in serum phospholipids: omega-3 and omega-6 fatty acids and the risk of prostate cancer. 1997 Int. J. Cancer pmid:9178806
Nakayama T et al. Lipid peroxidation in linoleic acid micelles caused by H2O2 in the presence of myoglobin. 1997 Biosci. Biotechnol. Biochem. pmid:9178558
Matsusue K et al. A highly toxic PCB produces unusual changes in the fatty acid composition of rat liver. 1997 Toxicol. Lett. pmid:9175845
Monette M and Lafleur M Influence of lipid chain unsaturation on melittin-induced micellization. 1996 Biophys. J. pmid:9172743
Palombo JD et al. Cyclic vs continuous enteral feeding with omega-3 and gamma-linolenic fatty acids: effects on modulation of phospholipid fatty acids in rat lung and liver immune cells. 1997 May-Jun JPEN J Parenter Enteral Nutr pmid:9168366
Rogers AE Diet and breast cancer: studies in laboratory animals. 1997 J. Nutr. pmid:9164267
Salomaa VV et al. Association of the fatty acid composition of serum phospholipids with hemostatic factors. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9157941
Luthria DL et al. Metabolites produced during the peroxisomal beta-oxidation of linoleate and arachidonate move to microsomes for conversion back to linoleate. 1997 Biochem. Biophys. Res. Commun. pmid:9144553
Cunnane SC and Anderson MJ Pure linoleate deficiency in the rat: influence on growth, accumulation of n-6 polyunsaturates, and [1-14C]linoleate oxidation. 1997 J. Lipid Res. pmid:9144095
Vargas F and Fuentes A Evidence of formation and participation of singlet oxygen in the in vitro phototoxicity of the combined diuretic triamterene and hydrochlorothiazide. 1997 Pharmazie pmid:9140146
Ohata T et al. Suppression of nitric oxide production in lipopolysaccharide-stimulated macrophage cells by omega 3 polyunsaturated fatty acids. 1997 Jpn. J. Cancer Res. pmid:9140106
Rao PU Nutrient composition and biological evaluation of mesta (Hibiscus sabdariffa) seeds. 1996 Plant Foods Hum Nutr pmid:9139301