Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rao PU | Nutrient composition and biological evaluation of mesta (Hibiscus sabdariffa) seeds. | 1996 | Plant Foods Hum Nutr | pmid:9139301 |
| Ohata T et al. | Suppression of nitric oxide production in lipopolysaccharide-stimulated macrophage cells by omega 3 polyunsaturated fatty acids. | 1997 | Jpn. J. Cancer Res. | pmid:9140106 |
| Vargas F and Fuentes A | Evidence of formation and participation of singlet oxygen in the in vitro phototoxicity of the combined diuretic triamterene and hydrochlorothiazide. | 1997 | Pharmazie | pmid:9140146 |
| Cunnane SC and Anderson MJ | Pure linoleate deficiency in the rat: influence on growth, accumulation of n-6 polyunsaturates, and [1-14C]linoleate oxidation. | 1997 | J. Lipid Res. | pmid:9144095 |
| Luthria DL et al. | Metabolites produced during the peroxisomal beta-oxidation of linoleate and arachidonate move to microsomes for conversion back to linoleate. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9144553 |
| Salomaa VV et al. | Association of the fatty acid composition of serum phospholipids with hemostatic factors. | 1997 | Arterioscler. Thromb. Vasc. Biol. | pmid:9157941 |
| Rogers AE | Diet and breast cancer: studies in laboratory animals. | 1997 | J. Nutr. | pmid:9164267 |
| Palombo JD et al. | Cyclic vs continuous enteral feeding with omega-3 and gamma-linolenic fatty acids: effects on modulation of phospholipid fatty acids in rat lung and liver immune cells. | 1997 May-Jun | JPEN J Parenter Enteral Nutr | pmid:9168366 |
| Monette M and Lafleur M | Influence of lipid chain unsaturation on melittin-induced micellization. | 1996 | Biophys. J. | pmid:9172743 |
| Matsusue K et al. | A highly toxic PCB produces unusual changes in the fatty acid composition of rat liver. | 1997 | Toxicol. Lett. | pmid:9175845 |
| Nakayama T et al. | Lipid peroxidation in linoleic acid micelles caused by H2O2 in the presence of myoglobin. | 1997 | Biosci. Biotechnol. Biochem. | pmid:9178558 |
| Harvei S et al. | Prediagnostic level of fatty acids in serum phospholipids: omega-3 and omega-6 fatty acids and the risk of prostate cancer. | 1997 | Int. J. Cancer | pmid:9178806 |
| Hornstra G and Kester AD | Effect of the dietary fat type on arterial thrombosis tendency: systematic studies with a rat model. | 1997 | Atherosclerosis | pmid:9180241 |
| Ding ST and Lilburn MS | Changes in fatty acid profiles in different lipid classes during late development of turkey embryos from two genetic lines. | 1997 | Poult. Sci. | pmid:9181615 |
| Banfi C et al. | Linoleic acid enhances the secretion of plasminogen activator inhibitor type 1 by HepG2 cells. | 1997 | J. Lipid Res. | pmid:9186904 |
| Memoli S et al. | Diffusible melanin-related metabolites are potent inhibitors of lipid peroxidation. | 1997 | Biochim. Biophys. Acta | pmid:9187303 |
| Ek BA et al. | Fatty acid binding proteins reduce 15-lipoxygenase-induced oxygenation of linoleic acid and arachidonic acid. | 1997 | Biochim. Biophys. Acta | pmid:9187305 |
| Berry H et al. | Excess substrate inhibition of soybean lipoxygenase-1 is mainly oxygen-dependent. | 1997 | FEBS Lett. | pmid:9188786 |
| Peres CM et al. | Transference of fatty acids from macrophages to lymphocytes in culture. | 1997 | Biochem. Soc. Trans. | pmid:9191389 |
| Sanderson P et al. | Dietary fish oil diminishes the antigen presentation activity of rat dendritic cells. | 1997 | Biochem. Soc. Trans. | pmid:9191396 |
| Sharpe M et al. | Ligation, inhibition, and activation of cytochrome c oxidase by fatty acids. | 1997 | Biochem. Cell Biol. | pmid:9192076 |
| Petrek JA et al. | Fatty acid composition of adipose tissue, an indication of dietary fatty acids, and breast cancer prognosis. | 1997 | J. Clin. Oncol. | pmid:9193329 |
| Sauer LA et al. | Dietary linoleic acid intake controls the arterial blood plasma concentration and the rates of growth and linoleic acid uptake and metabolism in hepatoma 7288CTC in Buffalo rats. | 1997 | J. Nutr. | pmid:9202100 |
| Schut HA et al. | DNA adducts of heterocyclic amines: formation, removal and inhibition by dietary components. | 1997 | Mutat. Res. | pmid:9202755 |
| Miura K et al. | The effects of unsaturated fatty acids, oxidizing agents and Michael reaction acceptors on the induction of N-ethylmaleimide reductase in Escherichia coli: possible application for drug design of chemoprotectors. | 1997 | Methods Find Exp Clin Pharmacol | pmid:9203161 |
| Yehuda S et al. | Essential fatty acid preparation improves biochemical and cognitive functions in experimental allergic encephalomyelitis rats. | 1997 | Eur. J. Pharmacol. | pmid:9203563 |
| Nicolosi RJ et al. | Dietary conjugated linoleic acid reduces plasma lipoproteins and early aortic atherosclerosis in hypercholesterolemic hamsters. | 1997 | Artery | pmid:9209699 |
| Stein CA | Controversies in the cellular pharmacology of oligodeoxynucleotides. | 1997 | Antisense Nucleic Acid Drug Dev. | pmid:9212912 |
| Usha S et al. | Mitogenic stimulation of primary cultures of lung epithelial cells by linoleic acid. | 1996 | Biochem. Cell Biol. | pmid:9213439 |
| Durgam VR and Fernandes G | The growth inhibitory effect of conjugated linoleic acid on MCF-7 cells is related to estrogen response system. | 1997 | Cancer Lett. | pmid:9215854 |
| Jira W et al. | Increased levels of lipid oxidation products in low density lipoproteins of patients suffering from rheumatoid arthritis. | 1997 | Chem. Phys. Lipids | pmid:9219348 |
| Quoc KP and Dubacq JP | Effect of growth temperature on the biosynthesis of eukaryotic lipid molecular species by the cyanobacterium Spirulina platensis. | 1997 | Biochim. Biophys. Acta | pmid:9219908 |
| Shi F et al. | Permeability and metabolic properties of a trophoblast cell line (HRP-1) derived from normal rat placenta. | 1997 | Exp. Cell Res. | pmid:9223380 |
| Haraguchi H et al. | Antioxidative action of diterpenoids from Podocarpus nagi. | 1997 | Planta Med. | pmid:9225601 |
| Lanson M et al. | Supplementation of MCF-7 cells with essential fatty acids induces the activation of protein kinase C in response to IGF-1. | 1997 | J Lipid Mediat Cell Signal | pmid:9246607 |
| Hannah JS et al. | High fat, high cholesterol diets alter low density lipoprotein size and binding affinity in monkeys. | 1997 | Atherosclerosis | pmid:9247355 |
| Thomson AB et al. | Nutrient uptake into undifferentiated and differentiated HT-29 cells in culture. | 1997 | Can. J. Physiol. Pharmacol. | pmid:9250367 |
| Bosca F et al. | Photophysical and photochemical characterization of a photosensitizing drug: a combined steady state photolysis and laser flash photolysis study on carprofen. | 1997 | Chem. Res. Toxicol. | pmid:9250417 |
| Parmentier HK et al. | Dietary unsaturated fatty acids affect antibody responses and growth of chickens divergently selected for humoral responses to sheep red blood cells. | 1997 | Poult. Sci. | pmid:9251147 |
| Howlett NG and Avery SV | Induction of lipid peroxidation during heavy metal stress in Saccharomyces cerevisiae and influence of plasma membrane fatty acid unsaturation. | 1997 | Appl. Environ. Microbiol. | pmid:9251184 |
| Siguel E | Essential fatty acid status in patients. | 1997 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:9252955 |
| Castelli F et al. | Dipalmitoylphosphatidylcholine/linoleic acid mixed unilamellar vesicles as model membranes for studies on novel free-radical scavengers. | 1997 | J Pharmacol Toxicol Methods | pmid:9253749 |
| Risé P et al. | Effects of simvastatin on the metabolism of polyunsaturated fatty acids and on glycerolipid, cholesterol, and de novo lipid synthesis in THP-1 cells. | 1997 | J. Lipid Res. | pmid:9254057 |
| Bakker N et al. | Adipose fatty acids and cancers of the breast, prostate and colon: an ecological study. EURAMIC Study Group. | 1997 | Int. J. Cancer | pmid:9259395 |
| Badart-Smook A et al. | Fetal growth is associated positively with maternal intake of riboflavin and negatively with maternal intake of linoleic acid. | 1997 | J Am Diet Assoc | pmid:9259708 |
| Brouwer DA et al. | The dietary fatty acids of patients with coronary artery disease and controls in Curaçao. Implications for primary and secondary prevention. | 1997 | West Indian Med J | pmid:9260535 |
| Feussner I et al. | Structural elucidation of oxygenated storage lipids in cucumber cotyledons. Implication of lipid body lipoxygenase in lipid mobilization during germination. | 1997 | J. Biol. Chem. | pmid:9261186 |
| Jenkins TC | Ruminal fermentation and nutrient digestion in sheep fed hydroxyethylsoyamide. | 1997 | J. Anim. Sci. | pmid:9263076 |
| Lopez Jimenez JA et al. | Linoleic acid metabolism in primary cultures of adult rat cardiomyocytes is impaired by aging. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9266846 |
| Fabritius D et al. | Biotransformation of linoleic acid with the Candida tropicalis M25 mutant. | 1997 | Appl. Microbiol. Biotechnol. | pmid:9274051 |
| Batna A et al. | Lipid peroxidation in presence of ebselen. | 1997 | Chem. Phys. Lipids | pmid:9275309 |
| Tiurina II et al. | [Palmitoylcarnitine-important component of lipid bilayer synaptosome membranes reparation system in oxidative stress]. | 1997 | Biull Eksp Biol Med | pmid:9280517 |
| Hou CT et al. | Microbial production of a novel trihydroxy unsaturated fatty acid from linoleic acid. | 1997 | J. Ind. Microbiol. Biotechnol. | pmid:9281851 |
| Usha S and Balakrishnan A | c-myc, c-H-ras, and IP3 elevation in 18:2 n-6 dependent proliferation of lung cells. | 1997 Jul-Aug | In Vitro Cell. Dev. Biol. Anim. | pmid:9282304 |
| Bambolkar S and Sainani GS | Evaluation of oxidative stress in diabetics with or without vascular complications. | 1995 | J Assoc Physicians India | pmid:9282629 |
| Carlson SE | Functional effects of increasing omega-3 fatty acid intake. | 1997 | J. Pediatr. | pmid:9290597 |
| Jensen CL et al. | Effect of dietary linoleic/alpha-linolenic acid ratio on growth and visual function of term infants. | 1997 | J. Pediatr. | pmid:9290604 |
| Skrzypczak-Jankun E et al. | Structure of soybean lipoxygenase L3 and a comparison with its L1 isoenzyme. | 1997 | Proteins | pmid:9294864 |
| López-Nicolás JM et al. | Kinetic characteristics of the enzymatic conversion in presence of cyclodextrins: study of the oxidation of polyunsaturated fatty acids by lipoxygenase. | 1997 | Biochim. Biophys. Acta | pmid:9295158 |
| Hall JA et al. | Lipid composition of hepatic and adipose tissues from normal cats and from cats with idiopathic hepatic lipidosis. | 1997 Jul-Aug | J. Vet. Intern. Med. | pmid:9298479 |
| de Waart FG et al. | Vitamin E supplementation in elderly lowers the oxidation rate of linoleic acid in LDL. | 1997 | Atherosclerosis | pmid:9298686 |
| Rusnak A et al. | Cardiolipin remodeling in a Chinese hamster lung fibroblast cell line deficient in oxidative energy production. | 1997 | J. Bioenerg. Biomembr. | pmid:9298714 |
| Moran JH et al. | Cytotoxicity of linoleic acid diols to renal proximal tubular cells. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9299596 |
| Hayakawa F et al. | DNA cleavage reaction and linoleic acid peroxidation induced by tea catechins in the presence of cupric ion. | 1997 | Biochim. Biophys. Acta | pmid:9305782 |
| Bolton-Smith C et al. | Evidence for age-related differences in the fatty acid composition of human adipose tissue, independent of diet. | 1997 | Eur J Clin Nutr | pmid:9306089 |
| Chinn KS et al. | Modulation of adjuvant-induced arthritis by dietary arachidonic acid in essential fatty acid-deficient rats. | 1997 | Lipids | pmid:9307941 |
| Chatterjee MT et al. | Alterations in cellular lipids may be responsible for the transient nature of the yeast heat shock response. | 1997 | Microbiology (Reading, Engl.) | pmid:9308188 |
| Meyer C et al. | Human kidney free fatty acid and glucose uptake: evidence for a renal glucose-fatty acid cycle. | 1997 | Am. J. Physiol. | pmid:9316458 |
| Eling TE et al. | Modulation of epidermal growth factor signal transduction by linoleic acid metabolites. | 1997 | Adv. Exp. Med. Biol. | pmid:9321970 |
| Louw L et al. | Keloids: peripheral and central differences in cell morphology and fatty acid compositions of lipids. | 1997 | Adv. Exp. Med. Biol. | pmid:9322000 |
| Ratnayake WM et al. | Essential fatty acids and their trans geometrical isomers in powdered and liquid infant formulas sold in Canada. | 1997 | J. Pediatr. Gastroenterol. Nutr. | pmid:9327370 |
| Heiskanen KM et al. | Effect of linoleic acid, linoleic acid anilide, and arachidonic acid on the expression of adhesion molecules on human neutrophils. | 1997 | Arch. Toxicol. | pmid:9332699 |
| Yamamoto A et al. | Improvement of the pulmonary absorption of (Asu1,7)-eel calcitonin by various absorption enhancers and their pulmonary toxicity in rats. | 1997 | J Pharm Sci | pmid:9344172 |
| O'donnell VB and Kühn H | Co-oxidation of NADH and NADPH by a mammalian 15-lipoxygenase: inhibition of lipoxygenase activity at near-physiological NADH concentrations. | 1997 | Biochem. J. | pmid:9355754 |
| Ali I and Steele JE | Fatty acids stimulate trehalose synthesis in trophocytes of the cockroach (Periplaneta americana) fat body. | 1997 | Gen. Comp. Endocrinol. | pmid:9356224 |
| Jie MS et al. | Synthesis and nuclear magnetic resonance properties of all geometrical isomers of conjugated linoleic acids. | 1997 | Lipids | pmid:9358429 |
| Anthony FA et al. | Psoralen-fatty acid adducts activate melanocyte protein kinase C: a proposed mechanism for melanogenesis induced by 8-methoxypsoralen and ultraviolet A light. | 1997 Feb-Apr | Photodermatol Photoimmunol Photomed | pmid:9361122 |
| Singer S et al. | Correlation of lipid content and composition with liposarcoma histology and grade. | 1997 Oct-Nov | Ann. Surg. Oncol. | pmid:9367021 |
| Mizushina Y et al. | The inhibitory action of fatty acids on DNA polymerase beta. | 1997 | Biochim. Biophys. Acta | pmid:9367179 |
| Kleinfeld AM et al. | Transport of long-chain native fatty acids across lipid bilayer membranes indicates that transbilayer flip-flop is rate limiting. | 1997 | Biochemistry | pmid:9369487 |
| Thompson H et al. | Morphological and biochemical status of the mammary gland as influenced by conjugated linoleic acid: implication for a reduction in mammary cancer risk. | 1997 | Cancer Res. | pmid:9371504 |
| Toborek M et al. | Linoleic acid potentiates TNF-mediated oxidative stress, disruption of calcium homeostasis, and apoptosis of cultured vascular endothelial cells. | 1997 | J. Lipid Res. | pmid:9374137 |
| Liu F et al. | Permeability properties of monolayers of the human trophoblast cell line BeWo. | 1997 | Am. J. Physiol. | pmid:9374645 |
| Guidot DM et al. | Modulating phosphatidic acid metabolism decreases oxidative injury in rat lungs. | 1997 | Am. J. Physiol. | pmid:9374722 |
| Priyadarsini KI | Free radical reactions of curcumin in membrane models. | 1997 | Free Radic. Biol. Med. | pmid:9378362 |
| Howlett NG and Avery SV | Relationship between cadmium sensitivity and degree of plasma membrane fatty acid unsaturation in Saccharomyces cerevisiae. | 1997 | Appl. Microbiol. Biotechnol. | pmid:9390462 |
| Dullaart RP et al. | Cholesteryl ester transfer protein gene polymorphism is a determinant of HDL cholesterol and of the lipoprotein response to a lipid-lowering diet in type 1 diabetes. | 1997 | Diabetes | pmid:9392500 |
| Rose DP | Effects of dietary fatty acids on breast and prostate cancers: evidence from in vitro experiments and animal studies. | 1997 | Am. J. Clin. Nutr. | pmid:9394709 |
| Ip C | Review of the effects of trans fatty acids, oleic acid, n-3 polyunsaturated fatty acids, and conjugated linoleic acid on mammary carcinogenesis in animals. | 1997 | Am. J. Clin. Nutr. | pmid:9394710 |
| Willett WC | Specific fatty acids and risks of breast and prostate cancer: dietary intake. | 1997 | Am. J. Clin. Nutr. | pmid:9394715 |
| Hoptroff MJ et al. | Influence of altered plasma membrane fatty acid composition on cesium transport characteristics and toxicity in Saccharomyces cerevisiae. | 1997 | Can. J. Microbiol. | pmid:9396148 |
| Schmid PC et al. | Generation and remodeling of highly polyunsaturated molecular species of rat hepatocyte phospholipids. | 1997 | Lipids | pmid:9397404 |
| Sjövall O et al. | Elution factors of synthetic oxotriacylglycerols as an aid in identification of peroxidized natural triacylglycerols by reverse-phase high-performance liquid chromatography with electrospray mass spectrometry. | 1997 | Lipids | pmid:9397407 |
| Christie WW et al. | Isomers in commercial samples of conjugated linoleic acid. | 1997 | Lipids | pmid:9397410 |
| Ali I and Steele JE | Evidence that free fatty acids in trophocytes of Periplaneta americana fat body may be regulated by the activity of phospholipase A2 and cyclooxygenase. | 1997 | Insect Biochem. Mol. Biol. | pmid:9404012 |
| Gniwotta C et al. | Prostaglandin F2-like compounds, F2-isoprostanes, are present in increased amounts in human atherosclerotic lesions. | 1997 | Arterioscler. Thromb. Vasc. Biol. | pmid:9409317 |
| van Niel MH and Beynen AC | The intake of polyunsaturated fatty acids by cats is reflected in their adipose tissue. | 1997 | Vet Q | pmid:9413110 |
| Kritchevsky D | Trans fatty acids and cardiovascular risk. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9430386 |
| Renaud SC | Dietary management of cardiovascular diseases. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9430390 |
| Zhou L et al. | Tissue uptake and interconversion of plasma unesterified 14C linoleic acid in the guinea pig. | 1997 | Biochim. Biophys. Acta | pmid:9434134 |