Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Gastroschisis D020139 1 associated lipids
Fat Necrosis D005218 1 associated lipids
Facial Nerve Diseases D005155 1 associated lipids
Refeeding Syndrome D055677 1 associated lipids
Child Nutrition Disorders D015362 1 associated lipids
Pellagra D010383 1 associated lipids
Refractive Errors D012030 1 associated lipids
Carcinoma, Krebs 2 D002287 1 associated lipids
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
Onchocerciasis D009855 1 associated lipids
Malaria, Cerebral D016779 1 associated lipids
Liposarcoma D008080 1 associated lipids
Disease D004194 2 associated lipids
Hypokinesia D018476 2 associated lipids
Darier Disease D007644 2 associated lipids
Circoviridae Infections D018173 2 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Lymphopenia D008231 2 associated lipids
Leptospirosis D007922 2 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Aneurysm D000783 2 associated lipids
Lactose Intolerance D007787 2 associated lipids
Infertility D007246 3 associated lipids
Wasting Syndrome D019282 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Hepatolenticular Degeneration D006527 3 associated lipids
Dermatitis, Toxicodendron D011040 3 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Melanosis D008548 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Dermatitis, Phototoxic D017484 4 associated lipids
Varicocele D014646 4 associated lipids
Biliary Atresia D001656 4 associated lipids
Cicatrix, Hypertrophic D017439 4 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Varicose Ulcer D014647 4 associated lipids
Choroidal Neovascularization D020256 5 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Tinea Versicolor D014010 5 associated lipids
Meningeal Neoplasms D008577 5 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Mucositis D052016 7 associated lipids
Nausea D009325 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Allman-Farinelli MA et al. Comparison of the effects of two low fat diets with different alpha-linolenic:linoleic acid ratios on coagulation and fibrinolysis. 1999 Atherosclerosis pmid:9920517
Natella F et al. Oxidative modification of human low-density lipoprotein by horseradish peroxidase in the absence of hydrogen peroxide. 1998 Free Radic. Res. pmid:9925035
Kalivianakis M et al. Fat malabsorption in cystic fibrosis patients receiving enzyme replacement therapy is due to impaired intestinal uptake of long-chain fatty acids. 1999 Am. J. Clin. Nutr. pmid:9925134
Began G et al. Inhibition of lipoxygenase 1 by phosphatidylcholine micelles-bound curcumin. 1998 Lipids pmid:9930409
Chyb S et al. Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL. 1999 Nature pmid:9930700
Toborek M and Hennig B The role of linoleic acid in endothelial cell gene expression. Relationship to atherosclerosis. 1998 Subcell. Biochem. pmid:9932524
Black PN The prevalence of allergic disease and linoleic acid in the diet. 1999 J. Allergy Clin. Immunol. pmid:9949330
Rao MS et al. Yield, protein, and oil quality of soybean genotypes selected for tofu production. 1998 Plant Foods Hum Nutr pmid:9950085
Zhou L and Nilsson A Fasting increases tissue uptake and interconversion of plasma unesterified linoleic acid in guinea pigs. 1999 Biochim. Biophys. Acta pmid:9989279
Sasaki T et al. Effects of dietary docosahexaenoic acid on surface molecules involved in T cell proliferation. 1999 Biochim. Biophys. Acta pmid:9989281