Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hamberg M et al. | Manganese lipoxygenase. Discovery of a bis-allylic hydroperoxide as product and intermediate in a lipoxygenase reaction. | 1998 | J. Biol. Chem. | pmid:9582346 |
Lee M et al. | Identification of non-heme diiron proteins that catalyze triple bond and epoxy group formation. | 1998 | Science | pmid:9572738 |
Hill EM et al. | Changes in expression of 15-lipoxygenase and prostaglandin-H synthase during differentiation of human tracheobronchial epithelial cells. | 1998 | Am. J. Respir. Cell Mol. Biol. | pmid:9569236 |
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Riambau V et al. | Effect of linoleic acid supplements on vessel wall hyperplasia in rabbits. | 1997 | Adv. Exp. Med. Biol. | pmid:9561150 |
Hörnsten L et al. | Bisallylic hydroxylation of linoleic and arachidonic acids by adult and fetal human liver microsomes and a comparison with human recombinant cytochromes P450. | 1997 | Adv. Exp. Med. Biol. | pmid:9561118 |
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Sugiyama K et al. | Dietary methionine level affects linoleic acid metabolism through phosphatidylethanolamine N-methylation in rats. | 1998 | Lipids | pmid:9560797 |
Kowaltowski AJ et al. | Activation of the potato plant uncoupling mitochondrial protein inhibits reactive oxygen species generation by the respiratory chain. | 1998 | FEBS Lett. | pmid:9559650 |
Akamatsu H and Horio T | The possible role of reactive oxygen species generated by neutrophils in mediating acne inflammation. | 1998 | Dermatology (Basel) | pmid:9557235 |
Rosenfield RL et al. | Mechanisms of androgen induction of sebocyte differentiation. | 1998 | Dermatology (Basel) | pmid:9557223 |
Romanini D et al. | Absorption and fluorescence spectra of polyene antibiotics in the presence of human serum albumin. | 1998 | Biochem. Mol. Biol. Int. | pmid:9556221 |
Mennen L et al. | Factor VIIa response to a fat-rich meal does not depend on fatty acid composition: a randomized controlled trial. | 1998 | Arterioscler. Thromb. Vasc. Biol. | pmid:9555866 |
Kataoka K et al. | Pathophysiologic studies of experimental chronic pancreatitis in rats induced by injection of zein-oleic acid-linoleic acid solution into the pancreatic duct. | 1998 | Pancreas | pmid:9548669 |