Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dubnov G and Berry EM | Omega-6/omega-3 fatty acid ratio: the Israeli paradox. | 2003 | World Rev Nutr Diet | pmid:14579685 |
Zampelas A et al. | Linoleic acid to alpha-linolenic acid ratio. From clinical trials to inflammatory markers of coronary artery disease. | 2003 | World Rev Nutr Diet | pmid:14579686 |
Hamazaki T and Okuyama H | The Japan Society for Lipid Nutrition recommends to reduce the intake of linoleic acid. A review and critique of the scientific evidence. | 2003 | World Rev Nutr Diet | pmid:14579687 |
Budowski P et al. | Mature milk from Israeli mothers is rich in polyunsaturated fatty acids. | 1994 | World Rev Nutr Diet | pmid:7871809 |
Postle AD et al. | Molecular species composition of plasma phosphatidylcholine in human pregnancy. | 1994 | World Rev Nutr Diet | pmid:7871810 |
Yavin E and Green P | Distribution, processing and selective esterification of essential fatty acid metabolites in the fetal brain. | 1994 | World Rev Nutr Diet | pmid:7871815 |
Lien EL | The ratio of linoleic acid to alpha-linolenic acid in infant formulas: current facts and future research directions. | 1994 | World Rev Nutr Diet | pmid:7871839 |
Simopoulos AP | Evolutionary aspects of the dietary omega-6:omega-3 fatty acid ratio: medical implications. | 2009 | World Rev Nutr Diet | pmid:19696523 |
Okuyama H et al. | New Cholesterol Guidelines for Longevity (2010). | 2011 | World Rev Nutr Diet | pmid:21865826 |
Legrand P et al. | Update of French nutritional recommendations for fatty acids. | 2011 | World Rev Nutr Diet | pmid:21865827 |
Holman RT | Highpoints in an affair with polyunsaturated fatty acids. | 1991 | World Rev Nutr Diet | pmid:2053355 |
Okuyama H et al. | Omega3 fatty acids effectively prevent coronary heart disease and other late-onset diseases--the excessive linoleic acid syndrome. | 2007 | World Rev Nutr Diet | pmid:17167282 |
Demmelmair H et al. | Polyunsaturated fatty acid metabolism during lactation. | 2001 | World Rev Nutr Diet | pmid:11935954 |
Sugano M | Isomeric fatty acids: their physiological significance and health implications. | 2001 | World Rev Nutr Diet | pmid:11935963 |
Cardoso CR et al. | Influence of topical administration of n-3 and n-6 essential and n-9 nonessential fatty acids on the healing of cutaneous wounds. | 2004 Mar-Apr | Wound Repair Regen | pmid:15086775 |
Byczkowski JZ and Kulkarni AP | Linoleate-dependent co-oxygenation of benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol by rat cytosolic lipoxygenase. | 1992 | Xenobiotica | pmid:1413876 |
Otsuka H et al. | [Studies on anti-inflammatory agents. IV. Anti-inflammatory constituents from roots of Panax ginseng C.A. Meyer (author's transl)]. | 1981 | Yakugaku Zasshi | pmid:7338798 |
Osaki Y et al. | [Antimutagenic and bactericidal substances in the fruit body of a Basidiomycete Agaricus blazei, Jun-17]. | 1994 | Yakugaku Zasshi | pmid:8014843 |
Yamamoto K et al. | [Antimutagenic substances in the Armeniacae semen and Persicae semen]. | 1992 | Yakugaku Zasshi | pmid:1294719 |
Fujii M | Pathogenesis of Diet-induced Atopic Dermatitis in Hairless Mice. | 2017 | Yakugaku Zasshi | pmid:28049895 |