Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Yang M et al. | Dietary conjugated linoleic acid protects against end stage disease of systemic lupus erythematosus in the NZB/W F1 mouse. | 2000 | Immunopharmacol Immunotoxicol | pmid:10946824 |
Magsino CH et al. | Nadolol inhibits reactive oxygen species generation by leukocytes and linoleic acid oxidation. | 2000 | Am. J. Cardiol. | pmid:10946040 |
Meilhac O et al. | Lipid peroxides induce expression of catalase in cultured vascular cells. | 2000 | J. Lipid Res. | pmid:10946007 |
Fabbri AA et al. | Early physiological and cytological events induced by wounding in potato tuber. | 2000 | J. Exp. Bot. | pmid:10937703 |
Zusman I et al. | Transplacental effects of maternal feeding with high fat diets on lipid exchange and response of the splenic lymphoid system in mice offspring exposed to low doses of carcinogen. | 2000 | Int. J. Mol. Med. | pmid:10934300 |
Kotani A et al. | Determination of plasma free fatty acids by high-performance liquid chromatography with electrochemical detection. | 2000 | Anal. Biochem. | pmid:10933857 |
Wingler K et al. | Gastrointestinal glutathione peroxidase prevents transport of lipid hydroperoxides in CaCo-2 cells. | 2000 | Gastroenterology | pmid:10930377 |
Dilika F et al. | Antibacterial activity of linoleic and oleic acids isolated from Helichrysum pedunculatum: a plant used during circumcision rites. | 2000 | Fitoterapia | pmid:10925024 |
Rosella O et al. | Polyunsaturated fatty acids reduce non-receptor-mediated transcellular permeation of protein across a model of intestinal epithelium in vitro. | 2000 | J. Gastroenterol. Hepatol. | pmid:10921416 |
Ip C et al. | Induction of apoptosis by conjugated linoleic acid in cultured mammary tumor cells and premalignant lesions of the rat mammary gland. | 2000 | Cancer Epidemiol. Biomarkers Prev. | pmid:10919739 |
Viola G et al. | In vitro studies of the phototoxic potential of the antidepressant drugs amitriptyline and imipramine. | 2000 | Farmaco | pmid:10919085 |
Kamlage B et al. | Linoleic acid conjugation by human intestinal microorganisms is inhibited by glucose and other substrates in vitro and in gnotobiotic rats. | 2000 | J. Nutr. | pmid:10917922 |
Jones S et al. | Isomers of conjugated linoleic acid (CLA) are incorporated into egg yolk lipids by CLA-fed laying hens. | 2000 | J. Nutr. | pmid:10917915 |
Vanella A et al. | L -propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector. | 2000 | Cell Biol. Toxicol. | pmid:10917565 |
Sakurada K et al. | cis-9,10-Methylenehexadecanoic acid inhibits contractility and actomyosin ATPase activity of guinea pig myocardium. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10913372 |
Wenger FA et al. | Does alpha-linolenic acid in combination with linoleic acid influence liver metastasis and hepatic lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters? | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10913224 |
Cantwell H et al. | The effect of a conjugated linoleic acid on superoxide dismutase, catalase and glutathione peroxidase in oxidatively-challenged liver cells. | 1998 | Biochem. Soc. Trans. | pmid:10909820 |
O'Shea M et al. | The effect of a conjugated dienoic derivative of linoleic acid on the in vitro growth of MCF-7 and SW480 human cancer cell lines. | 1998 | Biochem. Soc. Trans. | pmid:10909819 |
Boué C et al. | Trans fatty acids in adipose tissue of French women in relation to their dietary sources. | 2000 | Lipids | pmid:10907791 |
Groussard C et al. | Free radical scavenging and antioxidant effects of lactate ion: an in vitro study. | 2000 | J. Appl. Physiol. | pmid:10904049 |
Deva R et al. | Arachidonic acid stimulates cell growth and forms a novel oxygenated metabolite in Candida albicans. | 2000 | Biochim. Biophys. Acta | pmid:10903481 |
Mizushina Y et al. | Mode analysis of binding of fatty acids to mammalian DNA polymerases. | 2000 | Biochim. Biophys. Acta | pmid:10903472 |
Vargas F et al. | Studies on the in vitro phototoxicity of the antidiabetes drug glipizide. | 2000 | In Vitr Mol Toxicol | pmid:10900404 |
Yen GC and Chuang DY | Antioxidant properties of water extracts from Cassia tora L. in relation to the degree of roasting. | 2000 | J. Agric. Food Chem. | pmid:10898619 |
Freiberger CE et al. | Nutrient content of the edible leaves of seven wild plants from Niger. | 1998 | Plant Foods Hum Nutr | pmid:10890758 |
Moussa M et al. | Relationship between the fatty acid composition of rat lymphocytes and immune functions. | 2000 | Br. J. Nutr. | pmid:10884721 |
Tominaga K et al. | Effect of lipid polarization by centrifugation at different developmental stages on post-thaw survival of bovine in vitro produced 16-cell embryos. | 2000 | Theriogenology | pmid:10883852 |
Gonzalez B et al. | Metabolism of n -9, n -6 and n -3 fatty acids in hepatoma Morris 7777 cells. Preferential accumulation of linoleic acid in cardiolipin. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883061 |
Loreau O et al. | Large-scale preparation of (9Z,12E)-[1-(13)C]-octadeca-9,12-dienoic acid, (9Z,12Z,15E)-[1-(13)C]-octadeca-9,12,15-trienoic acid and their [1-(13)C] all-cis isomers. | 2000 | Chem. Phys. Lipids | pmid:10878236 |
Ponec M et al. | Covalently bound lipids in reconstructed human epithelia. | 2000 Mar-Apr | Acta Derm. Venereol. | pmid:10877125 |
Kumar KV et al. | Oxidant stress and essential fatty acids in patients with risk and established ARDS. | 2000 | Clin. Chim. Acta | pmid:10876008 |
Latour MA et al. | Effects of conjugated linoleic acid. 2. Embryonic and neonatal growth and circulating lipids. | 2000 | Poult. Sci. | pmid:10875762 |
Latour MA et al. | Effects of conjugated linoleic acid. 1. Fatty acid modification of yolks and neonatal fatty acid metabolism. | 2000 | Poult. Sci. | pmid:10875761 |
Decsi T and Koletzko B | Effects of protein-energy malnutrition and human immunodeficiency virus-1 infection on essential fatty acid metabolism in children. | 2000 | Nutrition | pmid:10869902 |
Watanabe T et al. | Formation of acyl radical in lipid peroxidation of linoleic acid by manganese-dependent peroxidase from Ceriporiopsis subvermispora and Bjerkandera adusta. | 2000 | Eur. J. Biochem. | pmid:10866827 |
Sehanputri PS and Hill CG | Biotechnology for the production of nutraceuticals enriched in conjugated linoleic acid: II. Multiresponse kinetics of the hydrolysis of corn oil by a Pseudomonas sp. lipase immobilized in a hollow-fiber reactor. | 2000 | Biotechnol. Bioeng. | pmid:10862683 |
Yoshiki Y et al. | Chemiluminescence and reactive oxygen scavenging activities of the hydrogen peroxide/gallic acid/lactoperoxidase system. | 2000 May-Jun | Luminescence | pmid:10862147 |
Williams JP et al. | The role of phosphatidylcholine in fatty acid exchange and desaturation in Brassica napus L. leaves. | 2000 | Biochem. J. | pmid:10861220 |
Kishino T et al. | Changes in liver fatty acid unsaturation after partial hepatectomy in the rat. | 2000 | Lipids | pmid:10858030 |
Hamberg M | New cyclopentenone fatty acids formed from linoleic and linolenic acids in potato. | 2000 | Lipids | pmid:10858019 |
Smith JC et al. | Orosensory factors in the ingestion of corn oil/sucrose mixtures by the rat. | 2000 Apr 1-15 | Physiol. Behav. | pmid:10854925 |
McHowat J and Creer MH | Selective plasmalogen substrate utilization by thrombin-stimulated Ca(2+)-independent PLA(2) in cardiomyocytes. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10843891 |
Maccarrone M et al. | Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833416 |
Bloodsworth A et al. | Manganese-porphyrin reactions with lipids and lipoproteins. | 2000 | Free Radic. Biol. Med. | pmid:10832063 |
Tokumura A et al. | Structural identification of phosphatidylcholines having an oxidatively shortened linoleate residue generated through its oxygenation with soybean or rabbit reticulocyte lipoxygenase. | 2000 | J. Lipid Res. | pmid:10828088 |
Azain MJ et al. | Dietary conjugated linoleic acid reduces rat adipose tissue cell size rather than cell number. | 2000 | J. Nutr. | pmid:10827208 |
Peebles ED et al. | Effects of dietary fat type and level on broiler breeder performance. | 2000 | Poult. Sci. | pmid:10824949 |
Tominaga K et al. | Effect of linoleic acid-albumin on post-thaw survival of in vitro-produced bovine embryos at the 16-cell stage. | 2000 | J. Vet. Med. Sci. | pmid:10823739 |
Dhiman TR et al. | Conjugated linoleic acid (CLA) content of milk from cows offered diets rich in linoleic and linolenic acid. | 2000 | J. Dairy Sci. | pmid:10821577 |
Pham TQ et al. | Antioxidant properties of crocin from Gardenia jasminoides Ellis and study of the reactions of crocin with linoleic acid and crocin with oxygen. | 2000 | J. Agric. Food Chem. | pmid:10820042 |