| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lactose Intolerance | D007787 | 2 associated lipids |
| Leptospirosis | D007922 | 2 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Liposarcoma | D008080 | 1 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Liver Diseases, Alcoholic | D008108 | 13 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ardestani A and Yazdanparast R | Inhibitory effects of ethyl acetate extract of Teucrium polium on in vitro protein glycoxidation. | 2007 | Food Chem. Toxicol. | pmid:17673348 |
| Labadaridis I et al. | Linoleic and arachidonic acid in perinatal asphyxia and prematurity. | 2007 | J. Matern. Fetal. Neonatal. Med. | pmid:17674280 |
| Todorov VT et al. | Peroxisome proliferator-activated receptor-gamma is involved in the control of renin gene expression. | 2007 | Hypertension | pmid:17785633 |
| Rosa A et al. | Evaluation of the antioxidant and cytotoxic activity of arzanol, a prenylated alpha-pyrone-phloroglucinol etherodimer from Helichrysum italicum subsp.microphyllum. | 2007 | Chem. Biol. Interact. | pmid:17194458 |
| Cho K et al. | Biochemical characterization of the dual positional specific maize lipoxygenase and the dependence of lagging and initial burst phenomenon on pH, substrate, and detergent during pre-steady state kinetics. | 2007 | J. Biochem. Mol. Biol. | pmid:17244489 |
| Yazdanparast R and Ardestani A | In vitro antioxidant and free radical scavenging activity of Cyperus rotundus. | 2007 | J Med Food | pmid:18158839 |
| Polesel J et al. | Nutrients intake and the risk of hepatocellular carcinoma in Italy. | 2007 | Eur. J. Cancer | pmid:17719221 |
| Koto T et al. | Eicosapentaenoic acid is anti-inflammatory in preventing choroidal neovascularization in mice. | 2007 | Invest. Ophthalmol. Vis. Sci. | pmid:17724224 |
| Aburai N et al. | Inhibitory activity of linoleic acid isolated from proso and Japanese millet toward histone deacetylase. | 2007 | Biosci. Biotechnol. Biochem. | pmid:17690455 |
| Muzio G et al. | PPARalpha and PP2A are involved in the proapoptotic effect of conjugated linoleic acid on human hepatoma cell line SK-HEP-1. | 2007 | Int. J. Cancer | pmid:17691108 |
| Breza JM et al. | Monosodium glutamate but not linoleic acid differentially activates gustatory neurons in the rat geniculate ganglion. | 2007 | Chem. Senses | pmid:17693416 |
| Azavache V et al. | [Is brown adipose tissue a store of long chain polyunsaturated fatty acids during postnatal developing brain?]. | 2007 | Arch Latinoam Nutr | pmid:17824193 |
| Fang IM et al. | Linoleic acid-induced expression of inducible nitric oxide synthase and cyclooxygenase II via p42/44 mitogen-activated protein kinase and nuclear factor-kappaB pathway in retinal pigment epithelial cells. | 2007 | Exp. Eye Res. | pmid:17825288 |
| Sclafani A et al. | CD36 gene deletion reduces fat preference and intake but not post-oral fat conditioning in mice. | 2007 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:17804586 |
| Shah M et al. | Lipid, glycemic, and insulin responses to meals rich in saturated, cis-monounsaturated, and polyunsaturated (n-3 and n-6) fatty acids in subjects with type 2 diabetes. | 2007 | Diabetes Care | pmid:17804680 |
| Zhang JS et al. | [Study on inhibitory effects of c9, t11-conjugated linoleic acid on migration of human gastric carcinoma cell line via cyclooxygenase-2 pathway]. | 2007 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:18399127 |
| Zheng XB et al. | [Analysis of lipid compounds of high-yielded rhizoma pinelliae growing in the west of Hubei province by gas chromatography-mass spectrometry]. | 2007 | Zhong Yao Cai | pmid:17918435 |
| Al-Khalifa A et al. | Effect of dietary hempseed intake on cardiac ischemia-reperfusion injury. | 2007 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:17122327 |
| Tunalier Z et al. | Antioxidant, anti-inflammatory, anti-nociceptive activities and composition of Lythrum salicaria L. extracts. | 2007 | J Ethnopharmacol | pmid:17125946 |
| Cosgrove MC et al. | Dietary nutrient intakes and skin-aging appearance among middle-aged American women. | 2007 | Am. J. Clin. Nutr. | pmid:17921406 |
| Ito T et al. | The homeotic protein AGAMOUS controls late stamen development by regulating a jasmonate biosynthetic gene in Arabidopsis. | 2007 | Plant Cell | pmid:17981996 |
| Balesteros MR et al. | Determination of olive oil acidity by CE. | 2007 | Electrophoresis | pmid:17941122 |
| Tannin-Spitz T et al. | Cucurbitacin glucosides: antioxidant and free-radical scavenging activities. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17942079 |
| Shin SC et al. | Development and biopharmaceutical evaluation of quinupramine-EVA matrix containing penetration enhancer for the enhanced transdermal absorption in rats. | 2007 | Pharm Dev Technol | pmid:17963142 |
| Takajo T et al. | Feedback activation of ferrous 5-lipoxygenase during leukotriene synthesis by coexisting linoleic acid. | 2007 | J. Lipid Res. | pmid:17337722 |
| Hamam F and Shahidi F | Acidolysis of tristearin with selected long-chain fatty acids. | 2007 | J. Agric. Food Chem. | pmid:17288439 |
| Schweiger D et al. | Inducible expression of 15-lipoxygenase-2 and 8-lipoxygenase inhibits cell growth via common signaling pathways. | 2007 | J. Lipid Res. | pmid:17164225 |
| Mattes RD | Effects of linoleic acid on sweet, sour, salty, and bitter taste thresholds and intensity ratings of adults. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:17290007 |
| Okuyama H et al. | Omega3 fatty acids effectively prevent coronary heart disease and other late-onset diseases--the excessive linoleic acid syndrome. | 2007 | World Rev Nutr Diet | pmid:17167282 |
| Ou L et al. | Conjugated linoleic acid induces apoptosis of murine mammary tumor cells via Bcl-2 loss. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17400188 |
| Okuyama H et al. | Why isn't the causal relationship between linoleic acid and mortalities from coronary heart disease and stroke revealed by clinical studies? | 2007 | World Rev Nutr Diet | pmid:17167283 |
| Okuyama H et al. | Mechanisms by which dietary fats affect coronary heart disease mortality. | 2007 | World Rev Nutr Diet | pmid:17167284 |
| Guo W et al. | Palmitate modulates intracellular signaling, induces endoplasmic reticulum stress, and causes apoptosis in mouse 3T3-L1 and rat primary preadipocytes. | 2007 | Am. J. Physiol. Endocrinol. Metab. | pmid:17519282 |
| Fang Q et al. | Etheno-DNA adduct formation in rats gavaged with linoleic acid, oleic acid and coconut oil is organ- and gender specific. | 2007 | Mutat. Res. | pmid:17521682 |
| Barla A et al. | Screening of antioxidant activity of three Euphorbia species from Turkey. | 2007 | Fitoterapia | pmid:17582698 |
| Tejero I et al. | A PM3/d specific reaction parameterization for iron atom in the hydrogen abstraction catalyzed by soybean lipoxygenase-1. | 2007 | J Comput Chem | pmid:17274015 |
| Sun CH et al. | [Effects of conjugated linoleic acid on expression of GLUT4 protein in skeletal muscle of insulin resistant rat]. | 2007 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:17484206 |
| Yoneda T et al. | The palatability of corn oil and linoleic acid to mice as measured by short-term two-bottle choice and licking tests. | 2007 | Physiol. Behav. | pmid:17459430 |
| Lu GP et al. | [Establishment of a cell-based high-throughput screening model for PPARdelta agonists]. | 2007 | Sheng Wu Gong Cheng Xue Bao | pmid:17460914 |
| Laidler P et al. | Does the inhibition of c-myc expression mediate the anti-tumor activity of PPAR's ligands in prostate cancer cell lines? | 2007 | Arch. Biochem. Biophys. | pmid:17466258 |
| Rosberg-Cody E et al. | Heterologous expression of linoleic acid isomerase from Propionibacterium acnes and anti-proliferative activity of recombinant trans-10, cis-12 conjugated linoleic acid. | 2007 | Microbiology (Reading, Engl.) | pmid:17660413 |
| Kumar S et al. | Antioxidant profile of ethoxyquin and some of its S, Se, and Te analogues. | 2007 | J. Org. Chem. | pmid:17602530 |
| Dufour C et al. | Inhibition of the peroxidation of linoleic acid by the flavonoid quercetin within their complex with human serum albumin. | 2007 | Free Radic. Biol. Med. | pmid:17603933 |
| Altmann R et al. | 13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells. | 2007 | Biochem. Pharmacol. | pmid:17604003 |
| Zeng YX et al. | Comparative analysis of volatile components from Clematis species growing in China. | 2007 | Anal. Chim. Acta | pmid:17606017 |
| Hodge AM et al. | Plasma phospholipid and dietary fatty acids as predictors of type 2 diabetes: interpreting the role of linoleic acid. | 2007 | Am. J. Clin. Nutr. | pmid:17616780 |
| Gu YX et al. | [Antioxidant activity of natural and cultured Cordyceps sp]. | 2007 | Zhongguo Zhong Yao Za Zhi | pmid:17672334 |
| TokuÅŸoÄŸlu O | The quality properties and saturated and unsaturated fatty acid profiles of quail egg: the alterations of fatty acids with process effects. | 2006 Nov-Dec | Int J Food Sci Nutr | pmid:17162332 |
| Troegeler-Meynadier A et al. | Rates and efficiencies of reactions of ruminal biohydrogenation of linoleic acid according to pH and polyunsaturated fatty acids concentrations. | 2006 Nov-Dec | Reprod. Nutr. Dev. | pmid:17169317 |
| Ryan E et al. | Fatty acid profile, tocopherol, squalene and phytosterol content of brazil, pecan, pine, pistachio and cashew nuts. | 2006 May-Jun | Int J Food Sci Nutr | pmid:17127473 |
| Voigt A et al. | Polyunsaturated but not conjugated linoleic acid supplementation of leukemic U937 cells can act as an amplification factor for photofrin-mediated photodynamic therapy. | 2006 May-Jun | Photochem. Photobiol. | pmid:16468943 |
| Lorenzi V et al. | Purification, product characterization and kinetic properties of lipoxygenase from olive fruit (Olea europaea L.). | 2006 Jul-Sep | Plant Physiol. Biochem. | pmid:17011785 |
| Templer J et al. | Influence of C18 long chain fatty acids on hydrogen metabolism. | 2006 Jan-Feb | Biotechnol. Prog. | pmid:16454511 |
| Castro IA et al. | Free radical scavenger and antioxidant capacity correlation of alpha-tocopherol and Trolox measured by three in vitro methodologies. | 2006 Feb-Mar | Int J Food Sci Nutr | pmid:16849116 |
| Glew RS and Vanderjagt D | Coping strategies and nutritional health in rural Niger: recommendations for consumption of wild plant foods in the Sahel. | 2006 Aug-Sep | Int J Food Sci Nutr | pmid:17135022 |
| Ennouri M et al. | Evaluation of some biological parameters of Opuntia ficus indica. 1. Influence of a seed oil supplemented diet on rats. | 2006 | Bioresour. Technol. | pmid:16129601 |
| Simón E et al. | trans-10,cis-12 conjugated linoleic acid prevents adiposity but not insulin resistance induced by an atherogenic diet in hamsters. | 2006 | J. Nutr. Biochem. | pmid:16111872 |
| Sasaki T et al. | Inhibitory effect of linoleic acid on transformation of IEC6 intestinal cells by in vitro azoxymethane treatment. | 2006 | Int. J. Cancer | pmid:16094650 |
| Yeh CS et al. | Fatty acid metabolism pathway play an important role in carcinogenesis of human colorectal cancers by Microarray-Bioinformatics analysis. | 2006 | Cancer Lett. | pmid:15885896 |
| Reis A et al. | Identification of linoleic acid free radicals and other breakdown products using spin trapping with liquid chromatography-electrospray tandem mass spectrometry. | 2006 | Biomed. Chromatogr. | pmid:15981198 |
| Burdge GC et al. | Lack of effect of meal fatty acid composition on postprandial lipid, glucose and insulin responses in men and women aged 50-65 years consuming their habitual diets. | 2006 | Br. J. Nutr. | pmid:16925854 |
| Reyes MR et al. | Estrogens are potentially the only steroids with an antioxidant role in pregnancy: in vitro evidence. | 2006 | Acta Obstet Gynecol Scand | pmid:16929413 |
| Raju M et al. | Micellar oleic and eicosapentaenoic acid but not linoleic acid influences the beta-carotene uptake and its cleavage into retinol in rats. | 2006 | Mol. Cell. Biochem. | pmid:16845492 |
| Belosludtsev K et al. | On the mechanism of palmitic acid-induced apoptosis: the role of a pore induced by palmitic acid and Ca2+ in mitochondria. | 2006 | J. Bioenerg. Biomembr. | pmid:16847595 |
| Leone A et al. | Lipoxygenase involvement in ripening strawberry. | 2006 | J. Agric. Food Chem. | pmid:16939347 |
| Hennig B et al. | Linoleic acid induces proinflammatory events in vascular endothelial cells via activation of PI3K/Akt and ERK1/2 signaling. | 2006 | J. Nutr. Biochem. | pmid:16563718 |
| Märk J et al. | Quantitation of furan and methylfuran formed in different precursor systems by proton transfer reaction mass spectrometry. | 2006 | J. Agric. Food Chem. | pmid:16569077 |
| Turpeinen AM et al. | Effects of conjugated linoleic acid on linoleic and linolenic acid metabolism in man. | 2006 | Br. J. Nutr. | pmid:16571152 |
| Smeets AJ and Westerterp-Plantenga MS | Satiety and substrate mobilization after oral fat stimulation. | 2006 | Br. J. Nutr. | pmid:16571160 |
| AbuGhazaleh AA et al. | Short communication: Eicosatrienoic acid and docosatrienoic acid do not promote vaccenic acid accumulation in mixed ruminal cultures. | 2006 | J. Dairy Sci. | pmid:17033021 |
| Amakura Y et al. | Characteristic long-chain fatty acid of Pleurocybella porrigens. | 2006 | Shokuhin Eiseigaku Zasshi | pmid:16984039 |
| John Wallace R et al. | Clostridium proteoclasticum: A ruminal bacterium that forms stearic acid from linoleic acid. | 2006 | FEMS Microbiol. Lett. | pmid:17147764 |
| Hurley MS et al. | Effects of fatty acids on skeletal muscle cell differentiation in vitro. | 2006 | Br. J. Nutr. | pmid:16512949 |
| Turchini GM et al. | Fatty acid metabolism in the freshwater fish Murray cod (Maccullochella peelii peelii) deduced by the whole-body fatty acid balance method. | 2006 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:16513379 |
| Moon HS et al. | Down-regulation of PPARgamma2-induced adipogenesis by PEGylated conjugated linoleic acid as the pro-drug: Attenuation of lipid accumulation and reduction of apoptosis. | 2006 | Arch. Biochem. Biophys. | pmid:17084379 |
| Haro AM et al. | [Linoleic conjugated acid: current interest in human nutrition]. | 2006 | Med Clin (Barc) | pmid:17043006 |
| Moore CS et al. | Oily fish reduces plasma triacylglycerols: a primary prevention study in overweight men and women. | 2006 | Nutrition | pmid:17027436 |
| Wang XL et al. | Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase. | 2006 | Diabetes | pmid:16873694 |
| Ollero M et al. | Evidence of increased flux to n-6 docosapentaenoic acid in phospholipids of pancreas from cftr-/- knockout mice. | 2006 | Metab. Clin. Exp. | pmid:16919538 |
| Koshiishi I et al. | Radical scavenger can scavenge lipid allyl radicals complexed with lipoxygenase at lower oxygen content. | 2006 | Biochem. J. | pmid:16396633 |
| Heikelä M et al. | Atomistic simulation studies of cholesteryl oleates: model for the core of lipoprotein particles. | 2006 | Biophys. J. | pmid:16399839 |
| Yaguchi T et al. | Linoleic acid derivative DCP-LA improves learning impairment in SAMP8. | 2006 | Neuroreport | pmid:16361960 |
| Sasaki T et al. | Peritoneal metastasis inhibition by linoleic acid with activation of PPARgamma in human gastrointestinal cancer cells. | 2006 | Virchows Arch. | pmid:16362414 |
| Górska A et al. | [Composition of linoleic and arachidonic acids in phosphatidylcholine of erythrocytes membrane and IL-6 and TNF-alpha in serum and C-reactive protein concentration in children with juvenile idiopathic arthritis]. | 2006 | Pol. Merkur. Lekarski | pmid:17405296 |
| Murthy KN et al. | Antioxidant property of Decalepis hamiltonii Wight & Arn. | 2006 | Indian J. Exp. Biol. | pmid:17131914 |
| Kisztelinski D et al. | Application of a continuous bioreactor cascade to study the effect of linoleic acid on hybridoma cell physiology. | 2006 | Biotechnol. Bioeng. | pmid:16894630 |
| Warensjö E et al. | Factor analysis of fatty acids in serum lipids as a measure of dietary fat quality in relation to the metabolic syndrome in men. | 2006 | Am. J. Clin. Nutr. | pmid:16895896 |
| Poole E and McQueen CE | Conjugated linoleic acid. | 2006 | Am J Health Syst Pharm | pmid:17057041 |
| Hu HZ et al. | Potentiation of TRPV3 channel function by unsaturated fatty acids. | 2006 | J. Cell. Physiol. | pmid:16557504 |
| Stentz FB and Kitabchi AE | Palmitic acid-induced activation of human T-lymphocytes and aortic endothelial cells with production of insulin receptors, reactive oxygen species, cytokines, and lipid peroxidation. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16782068 |
| Flood V et al. | Lutein and zeaxanthin dietary intake and age related macular degeneration. | 2006 | Br J Ophthalmol | pmid:16782963 |
| Kumazawa K et al. | Characterization of epoxydecenal isomers as potent odorants in black tea (Dimbula) infusion. | 2006 | J. Agric. Food Chem. | pmid:16787030 |
| Oliw EH et al. | Payne rearrangement during analysis of epoxyalcohols of linoleic and alpha-linolenic acids by normal phase liquid chromatography with tandem mass spectrometry. | 2006 | Anal. Biochem. | pmid:16712763 |
| Müller A et al. | Identification of conjugated linoleic acid elongation and beta-oxidation products by coupled silver-ion HPLC APPI-MS. | 2006 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:16713405 |
| Matkowski A and Piotrowska M | Antioxidant and free radical scavenging activities of some medicinal plants from the Lamiaceae. | 2006 | Fitoterapia | pmid:16713687 |
| Trujillo M et al. | Lipophilic hydroxytyrosyl esters. Antioxidant activity in lipid matrices and biological systems. | 2006 | J. Agric. Food Chem. | pmid:16719496 |
| Breksa AP and Manners GD | Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside. | 2006 | J. Agric. Food Chem. | pmid:16719503 |
| Oosthuizen W et al. | Polyunsaturated fatty acid intake is adversely related to liver function in HIV-infected subjects: the THUSA study. | 2006 | Am. J. Clin. Nutr. | pmid:16685065 |
| Szuchman A et al. | Exogenous N-linoleoyl tyrosine marker as a tool for the characterization of cellular oxidative stress in macrophages. | 2006 | Free Radic. Res. | pmid:16298758 |
| Friesen R and Innis SM | Maternal dietary fat alters amniotic fluid and fetal intestinal membrane essential n-6 and n-3 fatty acids in the rat. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16282365 |