Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Wasting Syndrome D019282 3 associated lipids
Endotoxemia D019446 27 associated lipids
Hepatitis C, Chronic D019698 12 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Gastroschisis D020139 1 associated lipids
Choroidal Neovascularization D020256 5 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Coronary Restenosis D023903 10 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Atherosclerosis D050197 85 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Mucositis D052016 7 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Refeeding Syndrome D055677 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Ivan M et al. Rumen fermentation and microbial population in lactating dairy cows receiving diets containing oilseeds rich in C-18 fatty acids. 2013 Br. J. Nutr. pmid:22850225
Alvheim AR et al. Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice. 2013 Br. J. Nutr. pmid:22883314
Lai MC et al. The natural PPAR agonist linoleic acid stimulated insulin release in the rat pancreas. 2013 J. Vet. Med. Sci. pmid:23832628
Bartók T et al. ESI-MS and MS/MS identification of the first ceramide analogues of fumonisin B₁ mycotoxin from a Fusarium verticillioides culture following RP-HPLC separation. 2013 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:23837460
Kälber T et al. Effect of feeding buckwheat and chicory silages on fatty acid profile and cheese-making properties of milk from dairy cows. 2013 J. Dairy Res. pmid:23253429
Gillingham LG et al. Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition. 2013 Am. J. Clin. Nutr. pmid:23221573
Carro M et al. Linoleic acid stimulates neutral lipid accumulation in lipid droplets of maturing bovine oocytes. 2013 Theriogenology pmid:23273433
Khan AA et al. Anticancer efficacy of a novel propofol-linoleic acid-loaded escheriosomal formulation against murine hepatocellular carcinoma. 2013 Nanomedicine (Lond) pmid:23311988
Graves JP et al. Characterization of four new mouse cytochrome P450 enzymes of the CYP2J subfamily. 2013 Drug Metab. Dispos. pmid:23315644
Carey AN et al. The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells. 2013 Nutr Neurosci pmid:23321679
Ramsden CE et al. Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis. 2013 BMJ pmid:23386268
Guo J et al. Selective transport of long-chain fatty acids by FAT/CD36 in skeletal muscle of broilers. 2013 Animal pmid:23031491
Kiernan M et al. The effect of the in vitro supplementation of exogenous long-chain fatty acids on bovine sperm cell function. 2013 Reprod. Fertil. Dev. pmid:23036717
Aboshi T et al. Biosynthesis of linoleic acid in Tyrophagus mites (Acarina: Acaridae). 2013 Insect Biochem. Mol. Biol. pmid:23973745
Ramirez AM et al. A trichome-specific linoleate lipoxygenase expressed during pyrethrin biosynthesis in pyrethrum. 2013 Lipids pmid:23893337
Hashim A et al. Antioxidant and α -amylase inhibitory property of phyllanthus virgatus L.: an in vitro and molecular interaction study. 2013 Biomed Res Int pmid:23957001
Navarro-Guillén C et al. Interaction between dietary levels of LC-PUFA and vegetable oil sources in Senegalese sole (Solea senegalensis) post-larvae: puzzling results suggesting complete biosynthesis pathway from C18 PUFA to DHA. 2013 Commun. Agric. Appl. Biol. Sci. pmid:25141696
Sato K et al. Selective and potent inhibitory effect of docosahexaenoic acid (DHA) on U46619-induced contraction in rat aorta. 2013 J Smooth Muscle Res pmid:24304639
Okada Y et al. Trans fatty acids exacerbate dextran sodium sulphate-induced colitis by promoting the up-regulation of macrophage-derived proinflammatory cytokines involved in T helper 17 cell polarization. 2013 Clin. Exp. Immunol. pmid:24028683
Yamagishi K et al. Plasma fatty acid composition and incident ischemic stroke in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study. 2013 Cerebrovasc. Dis. pmid:23920478