| MeSH term | MeSH ID | Detail |
|---|---|---|
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Ascites | D001201 | 25 associated lipids |
| Arteriosclerosis Obliterans | D001162 | 8 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Anorexia | D000855 | 8 associated lipids |
| Aneurysm | D000783 | 2 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Alopecia | D000505 | 14 associated lipids |
| Alcoholism | D000437 | 27 associated lipids |
| Alcoholic Intoxication | D000435 | 15 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Acidosis | D000138 | 13 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhang J et al. | Characteristics of fatty acid distribution is associated with colorectal cancer prognosis. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23465412 |
| Bellini MJ et al. | Effect of simvastatin on the uptake and metabolic conversion of palmitic, dihomo-gamma-linoleic and alpha-linolenic acids in A549 cells. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:14580370 |
| Al-Turkmani MR et al. | Fatty acid alterations and n-3 fatty acid supplementation in cystic fibrosis. | 2007 Nov-Dec | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18036797 |
| Cunnane SC | Commentary on the workshop statement. Essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10991770 |
| Horrobin DF | Commentary on the workshop statement: are we really sure that arachidonic acid and linoleic acid are bad things? | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10991771 |
| Ober MD and Hart CM | Attenuation of oxidant-mediated endothelial cell injury with docosahexaenoic acid: the role of intracellular iron. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774176 |
| Wander RC et al. | Influence of long-chain polyunsaturated fatty acids on oxidation of low density lipoprotein. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774178 |
| Harris WS | Linoleic acid and coronary heart disease. | 2008 Sep-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18951772 |
| Gonzalez B et al. | Metabolism of n -9, n -6 and n -3 fatty acids in hepatoma Morris 7777 cells. Preferential accumulation of linoleic acid in cardiolipin. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883061 |
| Soto-Guzman A et al. | Role of arachidonic acid metabolism in Stat5 activation induced by oleic acid in MDA-MB-231 breast cancer cells. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23332799 |
| Ramchurren N and Karmali R | Effects of gamma-linolenic and dihomo-gamma-linolenic acids on 7,12-dimethylbenz(alpha)anthracene-induced mammary tumors in rats. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7480079 |
| Mouradian M et al. | Key roles for GRB2-associated-binding protein 1, phosphatidylinositol-3-kinase, cyclooxygenase 2, prostaglandin E2 and transforming growth factor alpha in linoleic acid-induced upregulation of lung and breast cancer cell growth. | 2014 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24374147 |
| Chavali SR and Forse RA | Decreased production of interleukin-6 and prostaglandin E2 associated with inhibition of delta-5 desaturation of omega6 fatty acids in mice fed safflower oil diets supplemented with sesamol. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10718106 |
| Iwakiri Y et al. | Suppression of cyclooxygenase-2 and inducible nitric oxide synthase expression by conjugated linoleic acid in murine macrophages. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12468265 |
| Gibson R and Makrides M | α-Linolenate reduces the dietary requirement for linoleate in the growing rat. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22019216 |
| Rosing U and Olund A | Endometrial content of prostaglandin precursors during the menstrual cycle. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2780764 |
| Guesnet P et al. | α-Linolenate reduces the dietary requirement for linoleate in the growing rat. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21880475 |
| Kilian M et al. | Influence of conjugated and conventional linoleic acid on tumor growth and lipid peroxidation in pancreatic adenocarcinoma in hamster. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12878453 |
| Goodfriend TL et al. | An oxidized derivative of linoleic acid affects aldosterone secretion by adrenal cells in vitro. | 2002 Aug-Sep | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12324236 |
| Matsuba S et al. | Effect of dietary linoleate/alpha-linolenate balance on experimentally induced gastric injury in rats. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9888206 |
| Cunnane SC et al. | Carbon recycling into de novo lipogenesis is a major pathway in neonatal metabolism of linoleate and alpha-linolenate. | 1999 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10471127 |
| Salem N et al. | In vivo conversion of linoleic acid to arachidonic acid in human adults. | 1999 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10471130 |
| van der Schouw YT et al. | Fatty acid composition of serum lipids of mothers and their babies after normal and hypertensive pregnancies. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1815240 |
| Gibson RA et al. | Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22515943 |
| Glew RH et al. | Fatty acid composition of the milk lipids of Nepalese women: correlation between fatty acid composition of serum phospholipids and melting point. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728165 |
| Brestel EP and Koes MT | Heparin inhibits the "quasi-lipoxygenase" activity of hemoglobin toward linoleic acid by oxidant scavenging. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2500671 |
| Crandall DL et al. | Effect of varying concentrations of linoleic acid on alpha-adrenoceptor responses in spontaneously hypertensive rats. | 1988 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2845438 |
| Gregor JI et al. | Does enteral nutrition of dietary polyunsaturated fatty acids promote oxidative stress and tumour growth in ductal pancreatic cancer? Experimental trial in Syrian Hamster. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16226437 |
| Vaddadi KS | The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. | 1981 | Prostaglandins Med | pmid:6269135 |
| Kummerow FA et al. | Trans fatty acids in partially hydrogenated soybean oil inhibit prostacyclin release by endothelial cells in presence of high level of linoleic acid. | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17991616 |
| Sammon AM | Maize meal, non-esterified linoleic acid, and endemic cancer of the esophagus--preliminary findings. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10410386 |
| Yao X et al. | Effects of thyroid hormone status on metabolic pathways of arachidonic acid in mice and humans: A targeted metabolomic approach. | Prostaglandins Other Lipid Mediat. | pmid:25841349 | |
| Zabielski P et al. | The effect of high-fat diet on the sphingolipid pathway of signal transduction in regenerating rat liver. | 2010 | Prostaglandins Other Lipid Mediat. | pmid:20599517 |
| Rose DP and Connolly JM | Effects of fatty acids and eicosanoid synthesis inhibitors on the growth of two human prostate cancer cell lines. | 1991 | Prostate | pmid:2020620 |
| Cohen LA et al. | Effect of soy protein isolate and conjugated linoleic acid on the growth of Dunning R-3327-AT-1 rat prostate tumors. | 2003 | Prostate | pmid:12518321 |
| Griffiths G et al. | Effect of n-6 polyunsaturated fatty acids on growth and lipid composition of neoplastic and non-neoplastic canine prostate epithelial cell cultures. | 1997 | Prostate | pmid:9108883 |
| Connolly JM and Rose DP | Interactions between epidermal growth factor-mediated autocrine regulation and linoleic acid-stimulated growth of a human prostate cancer cell line. | 1992 | Prostate | pmid:1549552 |
| Verlotta A and Trono D | Expression, purification and refolding of active durum wheat (Triticum durum Desf.) secretory phospholipase A2 from inclusion bodies of Escherichia coli. | 2014 | Protein Expr. Purif. | pmid:24925645 |
| Skrzypczak-Jankun E et al. | Structure of soybean lipoxygenase L3 and a comparison with its L1 isoenzyme. | 1997 | Proteins | pmid:9294864 |
| Dobryniewski J et al. | [Biology of essential fatty acids (EFA)]. | 2007 | Prz. Lek. | pmid:17892040 |
| Buydens-Branchey L et al. | Polyunsaturated fatty acid status and relapse vulnerability in cocaine addicts. | 2003 | Psychiatry Res | pmid:14500111 |
| Bazinet RP et al. | Chronic valproate does not alter the kinetics of docosahexaenoic acid within brain phospholipids of the unanesthetized rat. | 2005 | Psychopharmacology (Berl.) | pmid:15986187 |
| Cheng G et al. | Relative validity of a 3 d estimated food record in German toddlers. | 2013 | Public Health Nutr | pmid:22874634 |
| Segovia-Siapco G et al. | Validation of a food-frequency questionnaire for measurement of nutrient intake in a dietary intervention study. | 2007 | Public Health Nutr | pmid:17261227 |
| Petrogianni M et al. | Additional benefit in CVD risk indices derived from the consumption of fortified milk when combined with a lifestyle intervention. | 2014 | Public Health Nutr | pmid:23249766 |
| Cantwell MM et al. | Development and validation of a food-frequency questionnaire for the determination of detailed fatty acid intakes. | 2005 | Public Health Nutr | pmid:15705250 |
| Maqbool A et al. | The skinny on tuna fat: health implications. | 2011 | Public Health Nutr | pmid:21324226 |
| Fremann D et al. | Dietary conjugated linoleic acid (CLA) intake assessment and possible biomarkers of CLA intake in young women. | 2002 | Public Health Nutr | pmid:12001981 |
| Ghisolfi J et al. | Nutrient intakes of children aged 1-2 years as a function of milk consumption, cows' milk or growing-up milk. | 2013 | Public Health Nutr | pmid:23098567 |
| Vinceti M et al. | A population-based case-control study of diet and melanoma risk in northern Italy. | 2005 | Public Health Nutr | pmid:16372927 |