| MeSH term | MeSH ID | Detail |
|---|---|---|
| Refeeding Syndrome | D055677 | 1 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Circoviridae Infections | D018173 | 2 associated lipids |
| Lymphopenia | D008231 | 2 associated lipids |
| Pneumonia, Viral | D011024 | 3 associated lipids |
| Constipation | D003248 | 8 associated lipids |
| Choroidal Neovascularization | D020256 | 5 associated lipids |
| Facial Nerve Diseases | D005155 | 1 associated lipids |
| Gastroesophageal Reflux | D005764 | 10 associated lipids |
| Community-Acquired Infections | D017714 | 8 associated lipids |
| Cicatrix, Hypertrophic | D017439 | 4 associated lipids |
| Varicose Ulcer | D014647 | 4 associated lipids |
| Lactose Intolerance | D007787 | 2 associated lipids |
| Gastroschisis | D020139 | 1 associated lipids |
| Fat Necrosis | D005218 | 1 associated lipids |
| Mucositis | D052016 | 7 associated lipids |
| Child Nutrition Disorders | D015362 | 1 associated lipids |
| Carcinoma, Krebs 2 | D002287 | 1 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kataoka K et al. | [A rat model of chronic pancreatic insufficiency induced by injection of zein-oleic acid-linoleic acid solution into the pancreatic duct]. | 1988 | Nihon Shokakibyo Gakkai Zasshi | pmid:3184515 |
| Pepin D et al. | Essential fatty acid pattern of glycerolipids in rat hepatocytes in primary culture and in coculture with rat liver epithelial cells. | 1988 | Lipids | pmid:3185111 |
| Takahashi R and Horrobin DF | Linoleic acid-induced fatty acid changes in platelet and aorta of the rat: effect of age and cholesterol. | 1988 | Lipids | pmid:3185125 |
| Bandyopadhyay GK et al. | Proliferative effects of insulin and epidermal growth factor on mouse mammary epithelial cells in primary culture. Enhancement by hydroxyeicosatetraenoic acids and synergism with prostaglandin E2. | 1988 | J. Biol. Chem. | pmid:3286636 |
| Truchetet E et al. | [Skin changes, pathophysiology and therapy in deficiency of essential fatty acids]. | 1988 | Z. Hautkr. | pmid:3291438 |
| Beaumelle BD and Vial HJ | Uninfected red cells from malaria-infected blood: alteration of fatty acid composition involving a serum protein: an in vivo and in vitro study. | 1988 | In Vitro Cell. Dev. Biol. | pmid:3294227 |
| Shimokawa T et al. | Effect of dietary alpha-linolenate/linoleate balance on mean survival time, incidence of stroke and blood pressure of spontaneously hypertensive rats. | 1988 | Life Sci. | pmid:2905408 |
| Bartels T et al. | Correlations between endogenous prostaglandin E formation in the bone and spongiosa density. | 1988 | Biomed. Biochim. Acta | pmid:3248114 |
| Rey HG et al. | Two-sided functional Na,K-ATPase-liposomes for characterizing the permeability and side of action of pump inhibitors. | 1988 | Prog. Clin. Biol. Res. | pmid:2906133 |
| De Deckere EA et al. | Effects of type and amount of dietary fat on rabbit and rat lymphocyte proliferation in vitro. | 1988 | J. Nutr. | pmid:3257261 |
| Perez RV et al. | Dietary immunoregulation of transfusion-induced immunosuppression. | 1988 | Transplantation | pmid:3258077 |
| Tiwari RK et al. | Influence of genotype on the phospholipid fatty acid composition of splenic T and B lymphocytes in MRL/MpJ-lpr/lpr mice. | 1988 | Immunol. Lett. | pmid:3258845 |
| Singh B et al. | Effect of high/low dietary linoleic acid levels on the function and fatty acid composition of T-lymphocytes of normal and diabetic rats. | 1988 | Diabetes Res. | pmid:3265900 |
| Perisho K et al. | Fatty acids of acylceramides from comedones and from the skin surface of acne patients and control subjects. | 1988 | J. Invest. Dermatol. | pmid:2964492 |
| Dietary fat and insulin receptor function in rat adipocytes. | 1988 | Nutr. Rev. | pmid:3277091 | |
| Bartels T et al. | [Effect of linoleic acid in food on spongioid bone density and prostaglandin biosynthesis in bones]. | 1988 | Beitr Orthop Traumatol | pmid:3228436 |
| Whitehead CC and Herron KM | Fatty acid requirements of breeding turkeys. | 1988 | Br. Poult. Sci. | pmid:3233502 |
| Parsons HG et al. | Supplemental calories improve essential fatty acid deficiency in cystic fibrosis patients. | 1988 | Pediatr. Res. | pmid:3211621 |
| Solakivi T et al. | Plasma apolipoprotein B in middle-aged Finnish men. Evidence for a regional gradient of apo B and lack of negative correlation between apo B and dietary linoleate in hyperapobetalipoproteinemia. | 1988 | Atherosclerosis | pmid:3214459 |
| Garg ML et al. | Differential effects of dietary linoleic and alpha-linolenic acid on lipid metabolism in rat tissues. | 1988 | Lipids | pmid:2903427 |
| Choi YS and Sugano M | Effects of dietary alpha- and gamma-linolenic acid on lipid metabolism in young and adult rats. | 1988 | Ann. Nutr. Metab. | pmid:2903713 |
| Venkatraman JT and Clandinin MT | Ribonucleic acid efflux from isolated mouse liver nuclei is altered by diet and genotypically determined change in nuclear envelope composition. | 1988 | Biochim. Biophys. Acta | pmid:2452656 |
| MacKenzie LW et al. | Prostacyclin biosynthesis by cultured human myometrial smooth muscle cells: dependency on arachidonic or linoleic acid in the culture medium. | 1988 | Am. J. Obstet. Gynecol. | pmid:3144917 |
| Wooten MW and Wrenn RW | Linoleic acid is a potent activator of protein kinase C type III-alpha isoform in pancreatic acinar cells; its role in amylase secretion. | 1988 | Biochem. Biophys. Res. Commun. | pmid:2454109 |
| Benadé AJ et al. | Plasma low density lipoprotein composition in relation to atherosclerosis in nutritionally defined Vervet monkeys. | 1988 | Atherosclerosis | pmid:3145748 |
| Salafsky B et al. | Schistosoma mansoni: analysis of cercarial transformation methods. | 1988 | Exp. Parasitol. | pmid:2458958 |
| Hashimoto A et al. | Effect of the dietary alpha-linolenate/linoleate balance on leukotriene production and histamine release in rats. | 1988 | Prostaglandins | pmid:2459732 |
| Bakalova RA et al. | [A mechanism of the inhibitory effect of alpha-tocopherol and its synthetic analogs on the oxidation of linoleic acid catalyzed by lipoxygenase from reticulocytes]. | 1988 | Dokl. Akad. Nauk SSSR | pmid:3135162 |
| MacGilchrist AJ et al. | Abetalipoproteinaemia in adults: role of vitamin therapy. | 1988 | J. Inherit. Metab. Dis. | pmid:3139930 |
| Innis SM and Yuen DE | Microsomal desaturation-elongation of linoleic acid following parenteral feeding with lipid emulsions in the rat. | 1988 | Lipids | pmid:3139951 |
| Garg ML et al. | Fish oil reduces cholesterol and arachidonic acid content more efficiently in rats fed diets containing low linoleic acid to saturated fatty acid ratios. | 1988 | Biochim. Biophys. Acta | pmid:2844278 |
| Schepp W et al. | Modulation of rat gastric mucosal prostaglandin E2 release by dietary linoleic acid: effects on gastric acid secretion and stress-induced mucosal damage. | 1988 | Gastroenterology | pmid:3163660 |
| Wright JR et al. | Essential fatty acid deficiency prevents multiple low-dose streptozotocin-induced diabetes in CD-1 mice. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3045812 |
| Galli C | Metabolic aspects of the biological roles of omega 3 fatty acids. | 1988 | Bibl Nutr Dieta | pmid:3060104 |
| Handelman GJ et al. | Biopsy method for human adipose with vitamin E and lipid measurements. | 1988 | Lipids | pmid:3172989 |
| Palmblad J and Gyllenhammar H | Effect of dietary lipids on immunity and inflammation. Review article. | 1988 | APMIS | pmid:2841953 |
| Albro PW et al. | Comparison of the effects of carbon tetrachloride and of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the disposition of linoleic acid in rat liver in vitro. | 1988 | Chem. Biol. Interact. | pmid:3135123 |
| Craven PA and DeRubertis FR | Role of activation of protein kinase C in the stimulation of colonic epithelial proliferation by unsaturated fatty acids. | 1988 | Gastroenterology | pmid:3135225 |
| Nakagawa Y and Waku K | Selective inhibition of free arachidonic acid production in activated alveolar macrophages by calmodulin antagonists. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3142466 |
| Rafael J et al. | Effect of dietary linoleic acid and essential fatty acid deficiency on resting metabolism, nonshivering thermogenesis and brown adipose tissue in the rat. | 1988 | J. Nutr. | pmid:3367242 |
| Simpson LO | The etiopathogenesis of premenstrual syndrome as a consequence of altered blood rheology: a new hypothesis. | 1988 | Med. Hypotheses | pmid:3367811 |
| Behrends W et al. | The glyoxysomal beta-oxidation system in cucumber seedlings: identification of enzymes required for the degradation of unsaturated fatty acids. | 1988 | Arch. Biochem. Biophys. | pmid:3369861 |
| Lindström P and Palmblad J | Dietary linoleic acid and rat neutrophil adhesion and chemotaxis. | 1988 | J Clin Lab Immunol | pmid:3373519 |
| Pschera H et al. | The influence of copper intrauterine device on fatty acid composition of cervical mucus lecithin. | 1988 | Contraception | pmid:3168451 |
| Schauder P et al. | [The effect of free fatty acids on the leucine oxidation of human lymphocytes]. | 1988 | Beitr Infusionther Klin Ernahr | pmid:3377747 |
| Kawooya JK and Law JH | Role of lipophorin in lipid transport to the insect egg. | 1988 | J. Biol. Chem. | pmid:3379043 |
| Bester R and Lochner A | Sarcolemmal phospholipid fatty acid composition and permeability. | 1988 | Biochim. Biophys. Acta | pmid:3382645 |
| Hiramatsu N et al. | Effects of dose levels of autoxidized linoleic acid on the drug-metabolizing system in rat liver. | 1988 | J. Nutr. Sci. Vitaminol. | pmid:3392612 |
| Sugiyama S et al. | The role of leukotoxin (9,10-epoxy-12-octadecenoate) in the genesis of coagulation abnormalities. | 1988 | Life Sci. | pmid:3398695 |
| Shasby DM et al. | Oxidants and conductance of cultured epithelial cell monolayers: inositol phospholipid hydrolysis. | 1988 | Am. J. Physiol. | pmid:3144179 |
| Crandall DL et al. | Effect of varying concentrations of linoleic acid on alpha-adrenoceptor responses in spontaneously hypertensive rats. | 1988 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2845438 |
| Norman A et al. | Postirradiation protection of chromosomes by linoleate. | 1988 | Int. J. Radiat. Biol. | pmid:2902149 |
| Hoffmann P et al. | Investigations on the mechanism of a diminished inotropic isoprenaline effect in isolated rat hearts after high linoleic acid diet. | 1988 | Biomed. Biochim. Acta | pmid:2854732 |
| Spector R | Fatty acid transport through the blood-brain barrier. | 1988 | J. Neurochem. | pmid:3335863 |
| Das UN | Effect of phorbolmyristate acetate on fatty acid uptake and distribution in human promyelocytic leukemia (HL-60) cells in vitro. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3144272 |
| Reynolds CH | Inactivation of soybean lipoxygenase by lipoxygenase inhibitors in the presence of 15-hydroperoxyeicosatetraenoic acid. | 1988 | Biochem. Pharmacol. | pmid:3144281 |
| Chander A and Fisher AB | Choline-phosphate cytidyltransferase activity and phosphatidylcholine synthesis in rat granular pneumocytes are increased with exogenous fatty acids. | 1988 | Biochim. Biophys. Acta | pmid:2893643 |
| Sebokova E et al. | Modulation of receptor-mediated gonadotropin action in rat testes by dietary fat. | 1988 | Am. J. Physiol. | pmid:2897795 |
| Fukuzawa K et al. | Site-specific induction of lipid peroxidation by iron in charged micelles. | 1988 | Arch. Biochem. Biophys. | pmid:2829725 |
| Hashimoto A et al. | [Effect of dietary alpha-linolenate/linoleate balance on the formation of leukotrienes in rat polymorphonuclear leukocytes]. | 1988 | Arerugi | pmid:2901255 |
| Markov KhM et al. | [Effect of dietary linoleic acid on the platelet aggregation, fatty acid composition of platelet phospholipids and synthesis of platelet prostaglandins in rats]. | 1988 Jul-Aug | Vopr. Med. Khim. | pmid:3195130 |
| Ghisolfi J et al. | Metabolic utilization of linoleic acid from fat emulsion in infants during total parenteral nutrition. | 1988 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:3138449 |
| Cotter R et al. | Fatty acid profiles in response to soybean oil lipid emulsion infusions in essential fatty acid-deficient miniature swine. | 1988 Mar-Apr | JPEN J Parenter Enteral Nutr | pmid:3129587 |
| Markov KhM and Kucherenko AG | [Effect of diets with various contents of linoleic acid on the prostaglandin system in the rat kidney]. | 1988 Mar-Apr | Vopr. Med. Khim. | pmid:3400199 |
| Clark RM | Lack of correlation between changes in the concentrations of linoleate and arachidonate in human milk relative to total milk lipid. | 1988 Nov-Dec | J. Pediatr. Gastroenterol. Nutr. | pmid:3143822 |
| Kageyama K et al. | Synergistic inhibition of DNA synthesis in Ehrlich ascites tumour cells by a combination of unsaturated fatty acids and hyperthermia. | 1989 | J Appl Toxicol | pmid:2926093 |
| Booker ML et al. | Effect of dietary cholesterol on phosphatidylcholines and phosphatidylethanolamines in bile and gallbladder mucosa in the prairie dog. | 1989 | Gastroenterology | pmid:2507386 |
| Garcia Zevallos M and Farkas T | Manipulation of plasma membrane physical state affects desaturase activity in rat lymphocytes. | 1989 | Arch. Biochem. Biophys. | pmid:2786374 |
| Fujiyama-Fujiwara Y et al. | Metabolism of gamma-linolenic acid in primary cultures of rat hepatocytes and in Hep G2 cells. | 1989 | J. Nutr. Sci. Vitaminol. | pmid:2576804 |
| Kihata M | [Effects of exogenous insulin on oxidation of glucose and fatty acid in septic rats]. | 1989 | Nihon Geka Gakkai Zasshi | pmid:2668730 |
| Perez RV et al. | Augmentation of donor-specific transfusion and cyclosporine effects with dietary linoleic acid. | 1989 | Transplantation | pmid:2660353 |
| Fairbank J et al. | Octadeca-9,11-dienoic acid in cervical intraepithelial neoplasia: a colposcopic study. | 1989 | Clin. Chim. Acta | pmid:2612010 |
| Park JH et al. | Effects of dietary linoleic acid on mucosal adaptation after small bowel resection. | 1989 | Digestion | pmid:2612750 |
| Hiramatsu N et al. | Effects of dietary pantethine levels on drug-metabolizing system in the liver of rats orally administered varying amounts of autoxidized linoleate. | 1989 | J. Nutr. Sci. Vitaminol. | pmid:2585150 |
| Chanussot B et al. | Liver microsomal delta 6 and delta 5 linoleic acid desaturation in female BB rats. | 1989 | Diabetologia | pmid:2591647 |
| Clouet P et al. | Pathway of alpha-linolenic acid through the mitochondrial outer membrane in the rat liver and influence on the rate of oxidation. Comparison with linoleic and oleic acids. | 1989 | Biochem. J. | pmid:2597132 |
| Bayorh MA et al. | Acute and chronic effects of eicosapentaenoic acid (EPA) on the cardiovascular system. | 1989 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:2558405 |
| Meikle AW et al. | Nonesterified fatty acids modulate steroidogenesis in mouse Leydig cells. | 1989 | Am. J. Physiol. | pmid:2558577 |
| Hennig B and Watkins BA | Linoleic acid and linolenic acid: effect on permeability properties of cultured endothelial cell monolayers. | 1989 | Am. J. Clin. Nutr. | pmid:2563626 |
| Grossi IM et al. | Bidirectional control of membrane expression and/or activation of the tumor cell IRGpIIb/IIIa receptor and tumor cell adhesion by lipoxygenase products of arachidonic acid and linoleic acid. | 1989 | Cancer Res. | pmid:2492204 |
| Gardner HW | Soybean lipoxygenase-1 enzymically forms both (9S)- and (13S)-hydroperoxides from linoleic acid by a pH-dependent mechanism. | 1989 | Biochim. Biophys. Acta | pmid:2492826 |
| Anderson GJ and Connor WE | On the demonstration of omega-3 essential-fatty-acid deficiency in humans. | 1989 | Am. J. Clin. Nutr. | pmid:2494878 |
| Byczkowski JZ and Kulkarni AP | Lipoxygenase-catalyzed epoxidation of benzo(a)pyrene-7,8-dihydrodiol. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2494999 |
| Kaduce TL et al. | Formation of 9-hydroxyoctadecadienoic acid from linoleic acid in endothelial cells. | 1989 | J. Biol. Chem. | pmid:2496121 |
| Hamazaki S et al. | Oxygen reduction and lipid peroxidation by iron chelates with special reference to ferric nitrilotriacetate. | 1989 | Arch. Biochem. Biophys. | pmid:2500058 |
| Imaizumi K et al. | Effect of phosphatidylethanolamine and its constituent base on the metabolism of linoleic acid in rat liver. | 1989 | Biochim. Biophys. Acta | pmid:2508745 |
| Furth EE et al. | The effect of endogenous essential and nonessential fatty acids on the uptake and subsequent agonist-induced release of arachidonate. | 1989 | J. Biol. Chem. | pmid:2553711 |
| Hansen O | Characterization of fatty acid interaction with ouabain and vanadate binding to (Na+ + K+)-activated ATPase. | 1989 | Biochim. Biophys. Acta | pmid:2554979 |
| D'Aquino M et al. | Vitamin A and glutathione-mediated free radical damage: competing reactions with polyunsaturated fatty acids and vitamin C. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2568114 |
| Blond JP et al. | Effect of fenofibrate treatment on linoleic acid desaturation in liver of obese Zucker rats. | 1989 | Biochem. Pharmacol. | pmid:2764996 |
| Hrboticky N et al. | Effect of linoleic acid-rich infant formula feeding on brain synaptosomal lipid accretion and enzyme thermotropic behavior in the piglet. | 1989 | J. Lipid Res. | pmid:2769072 |
| Braughler JM and Pregenzer JF | The 21-aminosteroid inhibitors of lipid peroxidation: reactions with lipid peroxyl and phenoxy radicals. | 1989 | Free Radic. Biol. Med. | pmid:2806938 |
| Hrelia S et al. | Age-related changes in linoleate and alpha-linolenate desaturation by rat liver microsomes. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2570573 |
| Toda S et al. | Peroxidation of linoleic acid induced by interaction with haemoglobin and hydrogen peroxide. | 1989 | Free Radic. Res. Commun. | pmid:2806947 |
| Rose DP and Connolly JM | Stimulation of growth of human breast cancer cell lines in culture by linoleic acid. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2803300 |
| Mahfouz MM et al. | Changes of linoleic acid metabolism and cellular phospholipid fatty acid composition in LLC-PK cells cultured at low magnesium concentrations. | 1989 | Biochim. Biophys. Acta | pmid:2804072 |
| Furr HC et al. | The effect of dietary fatty acid composition on liver retinyl ester (vitamin A ester) composition in the rat. | 1989 | J. Nutr. | pmid:2703916 |
| Chen Q et al. | Hydrolysis of triacylglycerol arachidonic and linoleic acid ester bonds by human pancreatic lipase and carboxyl ester lipase. | 1989 | Biochim. Biophys. Acta | pmid:2503032 |
| Chapkin RS et al. | Linoleic acid metabolism in metastatic and nonmetastatic murine mammary tumor cells. | 1989 | Cancer Res. | pmid:2503244 |
| Mohsenin V and Gee JL | Oxidation of alpha 1-protease inhibitor: role of lipid peroxidation products. | 1989 | J. Appl. Physiol. | pmid:2787317 |