Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Refeeding Syndrome D055677 1 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Circoviridae Infections D018173 2 associated lipids
Lymphopenia D008231 2 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Constipation D003248 8 associated lipids
Choroidal Neovascularization D020256 5 associated lipids
Facial Nerve Diseases D005155 1 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Cicatrix, Hypertrophic D017439 4 associated lipids
Varicose Ulcer D014647 4 associated lipids
Lactose Intolerance D007787 2 associated lipids
Gastroschisis D020139 1 associated lipids
Fat Necrosis D005218 1 associated lipids
Mucositis D052016 7 associated lipids
Child Nutrition Disorders D015362 1 associated lipids
Carcinoma, Krebs 2 D002287 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Tang KH et al. [Oil content of Pyracantha seeds and its relations to soil nutrients in northwestern Hunan Province]. 2007 Ying Yong Sheng Tai Xue Bao pmid:17974264
He J et al. Correlation of polyunsaturated fatty acids with the cold adaptation of Rhodotorula glutinis. 2015 Yeast pmid:26284451
Yazawa H et al. Production of polyunsaturated fatty acids in yeast Saccharomyces cerevisiae and its relation to alkaline pH tolerance. 2009 Yeast pmid:19243079
Kainou K et al. Isolation of Delta12 and omega3-fatty acid desaturase genes from the yeast Kluyveromyces lactis and their heterologous expression to produce linoleic and alpha-linolenic acids in Saccharomyces cerevisiae. 2006 Yeast pmid:16823888
Wang SC et al. [Analysis of supercritical fluid extracts of Radix caulophylli with gas chromatography-mass spectrometry]. 2007 Yao Xue Xue Bao pmid:17703777
Bian RL et al. [Antianaphylactic components of Asarum forbsii Maxin]. 1990 Yao Xue Xue Bao pmid:2099089
Zhao CX et al. [Chemical components in essential oils from tender branches and leaves of Rhododendron]. 2005 Yao Xue Xue Bao pmid:16342692
Nakagawa Y [Metabolism and biological function of cardiolipin]. 2013 Yakugaku Zasshi pmid:23649397
Otsuka H et al. [Studies on anti-inflammatory agents. IV. Anti-inflammatory constituents from roots of Panax ginseng C.A. Meyer (author's transl)]. 1981 Yakugaku Zasshi pmid:7338798
Osaki Y et al. [Antimutagenic and bactericidal substances in the fruit body of a Basidiomycete Agaricus blazei, Jun-17]. 1994 Yakugaku Zasshi pmid:8014843
Yamamoto K et al. [Antimutagenic substances in the Armeniacae semen and Persicae semen]. 1992 Yakugaku Zasshi pmid:1294719
Toda S et al. [Inhibitory effects of methanol extracts of crude drugs on the air oxidation of linoleic acid]. 1984 Yakugaku Zasshi pmid:6491877
Fujii M Pathogenesis of Diet-induced Atopic Dermatitis in Hairless Mice. 2017 Yakugaku Zasshi pmid:28049895
Okuyama H [Need to change the direction of cholesterol-related medication--a problem of great urgency]. 2005 Yakugaku Zasshi pmid:16272805
Byczkowski JZ and Kulkarni AP Linoleate-dependent co-oxygenation of benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol by rat cytosolic lipoxygenase. 1992 Xenobiotica pmid:1413876
Cardoso CR et al. Influence of topical administration of n-3 and n-6 essential and n-9 nonessential fatty acids on the healing of cutaneous wounds. 2004 Mar-Apr Wound Repair Regen pmid:15086775
Dubnov G and Berry EM Omega-6/omega-3 fatty acid ratio: the Israeli paradox. 2003 World Rev Nutr Diet pmid:14579685
Zampelas A et al. Linoleic acid to alpha-linolenic acid ratio. From clinical trials to inflammatory markers of coronary artery disease. 2003 World Rev Nutr Diet pmid:14579686
Hamazaki T and Okuyama H The Japan Society for Lipid Nutrition recommends to reduce the intake of linoleic acid. A review and critique of the scientific evidence. 2003 World Rev Nutr Diet pmid:14579687
Budowski P et al. Mature milk from Israeli mothers is rich in polyunsaturated fatty acids. 1994 World Rev Nutr Diet pmid:7871809
Postle AD et al. Molecular species composition of plasma phosphatidylcholine in human pregnancy. 1994 World Rev Nutr Diet pmid:7871810
Yavin E and Green P Distribution, processing and selective esterification of essential fatty acid metabolites in the fetal brain. 1994 World Rev Nutr Diet pmid:7871815
Lien EL The ratio of linoleic acid to alpha-linolenic acid in infant formulas: current facts and future research directions. 1994 World Rev Nutr Diet pmid:7871839
Simopoulos AP Evolutionary aspects of the dietary omega-6:omega-3 fatty acid ratio: medical implications. 2009 World Rev Nutr Diet pmid:19696523
Ramsden CE et al. All PUFAs are not created equal: absence of CHD benefit specific to linoleic acid in randomized controlled trials and prospective observational cohorts. 2011 World Rev Nutr Diet pmid:21865817
Okuyama H et al. New Cholesterol Guidelines for Longevity (2010). 2011 World Rev Nutr Diet pmid:21865826
Watkins BA et al. Designed eggs containing conjugated linoleic acids and omega-3 polyunsaturated fatty acids. 2001 World Rev Nutr Diet pmid:11545041
Legrand P et al. Update of French nutritional recommendations for fatty acids. 2011 World Rev Nutr Diet pmid:21865827
Holman RT Highpoints in an affair with polyunsaturated fatty acids. 1991 World Rev Nutr Diet pmid:2053355
Bibus DM and Stitt PA Metabolism of alpha-linolenic acid from flaxseed in dogs. 1998 World Rev Nutr Diet pmid:9648515
Okuyama H et al. Omega3 fatty acids effectively prevent coronary heart disease and other late-onset diseases--the excessive linoleic acid syndrome. 2007 World Rev Nutr Diet pmid:17167282
Okuyama H et al. Why isn't the causal relationship between linoleic acid and mortalities from coronary heart disease and stroke revealed by clinical studies? 2007 World Rev Nutr Diet pmid:17167283
Okuyama H et al. Mechanisms by which dietary fats affect coronary heart disease mortality. 2007 World Rev Nutr Diet pmid:17167284
Okuyama H et al. Cancers common in the USA are stimulated by omega 6 fatty acids and large amounts of animal fats, but suppressed by omega 3 fatty acids and cholesterol. 2007 World Rev Nutr Diet pmid:17167285
Demmelmair H et al. Polyunsaturated fatty acid metabolism during lactation. 2001 World Rev Nutr Diet pmid:11935954
Sugano M Isomeric fatty acids: their physiological significance and health implications. 2001 World Rev Nutr Diet pmid:11935963
Okuyama H and Sakai K Effects of dietary oils with extreme omega 3/omega 6 ratios--selective incorporation and differential catabolism. 1991 World Rev Nutr Diet pmid:1675826
Zheng HF et al. Effects of unsaturated fatty acids on calcium-activated potassium current in gastric myocytes of guinea pigs. 2005 World J. Gastroenterol. pmid:15655819
Chen BQ et al. Effects of c9,t11-conjugated linoleic acid on adhesion of human gastric carcinoma cell line SGC-7901. 2004 World J. Gastroenterol. pmid:15133841
Chen BQ et al. Inhibition of conjugated linoleic acid on mouse forestomach neoplasia induced by benzo (a) pyrene and chemopreventive mechanisms. 2003 World J. Gastroenterol. pmid:12508349
Brouwer DA et al. The dietary fatty acids of patients with coronary artery disease and controls in Curaçao. Implications for primary and secondary prevention. 1997 West Indian Med J pmid:9260535
Xue Y et al. [Effects of conjugated linoleic acid on the metastasis of mouse melanoma B16-MB]. 2001 Wei Sheng Yan Jiu pmid:11255760
Lu WH et al. [Screening and identification of a strain for hydroxylation of nicotinic acid]. 2005 Wei Sheng Wu Xue Bao pmid:15847152
Moon C et al. Modeling sulfate removal by inhibited mesophilic mixed anaerobic communities using a statistical approach. 2013 Water Res. pmid:23466036
Markov KhM et al. [Effect of dietary linoleic acid on the platelet aggregation, fatty acid composition of platelet phospholipids and synthesis of platelet prostaglandins in rats]. 1988 Jul-Aug Vopr. Med. Khim. pmid:3195130
Bondarenko LB et al. [Effect of 1,25-dihydroxyvitamin D3 on 15-lipoxygenase activity]. 1995 May-Jun Vopr. Med. Khim. pmid:8585174
Markov KhM and Kucherenko AG [Effect of diets with various contents of linoleic acid on the prostaglandin system in the rat kidney]. 1988 Mar-Apr Vopr. Med. Khim. pmid:3400199
Buko VU et al. [Changes in the fatty acid composition of erythrocyte membranes in patients with chronic alcoholism under the effect of a diet enriched with linoleic acid]. 1989 Nov-Dec Vopr Pitan pmid:2629246
ONDREICHKA R et al. [CHANGES IN THE CHEMICAL AND PHYSICAL PROPERTIES OF LARD AND BUTTER DURING HEATING]. 1963 Nov-Dec Vopr Pitan pmid:14149605
Martinchik AN [Nutritional value of sesame seeds]. 2011 Vopr Pitan pmid:21842753