| MeSH term | MeSH ID | Detail |
|---|---|---|
| Refeeding Syndrome | D055677 | 1 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Circoviridae Infections | D018173 | 2 associated lipids |
| Lymphopenia | D008231 | 2 associated lipids |
| Pneumonia, Viral | D011024 | 3 associated lipids |
| Constipation | D003248 | 8 associated lipids |
| Choroidal Neovascularization | D020256 | 5 associated lipids |
| Facial Nerve Diseases | D005155 | 1 associated lipids |
| Gastroesophageal Reflux | D005764 | 10 associated lipids |
| Community-Acquired Infections | D017714 | 8 associated lipids |
| Cicatrix, Hypertrophic | D017439 | 4 associated lipids |
| Varicose Ulcer | D014647 | 4 associated lipids |
| Lactose Intolerance | D007787 | 2 associated lipids |
| Gastroschisis | D020139 | 1 associated lipids |
| Fat Necrosis | D005218 | 1 associated lipids |
| Mucositis | D052016 | 7 associated lipids |
| Child Nutrition Disorders | D015362 | 1 associated lipids |
| Carcinoma, Krebs 2 | D002287 | 1 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- J. Lipid Res. (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shirakawa J et al. | Protective effects of dipeptidyl peptidase-4 (DPP-4) inhibitor against increased β cell apoptosis induced by dietary sucrose and linoleic acid in mice with diabetes. | 2011 | J. Biol. Chem. | pmid:21613229 |
| Labayen I et al. | Associations of birth weight with serum long chain polyunsaturated fatty acids in adolescents; the HELENA study. | 2011 | Atherosclerosis | pmid:21550607 |
| Monfregola L et al. | Physical and water sorption properties of chemically modified pectin with an environmentally friendly process. | 2011 | Biomacromolecules | pmid:21553919 |
| Shin D et al. | Dietary combination effects of conjugated linoleic acid and flaxseed or fish oil on the concentration of linoleic and arachidonic acid in poultry meat. | 2011 | Poult. Sci. | pmid:21597077 |
| Yepuri G et al. | Dietary modulation of body composition and insulin sensitivity during catch-up growth in rats: effects of oils rich in n-6 or n-3 PUFA. | 2011 | Br. J. Nutr. | pmid:21281526 |
| Wang L et al. | Acute stimulation of glucagon secretion by linoleic acid results from GPR40 activation and [Ca2+]i increase in pancreatic islet {alpha}-cells. | 2011 | J. Endocrinol. | pmid:21565851 |
| Nigam S et al. | On mechanism of quorum sensing in Candida albicans by 3(R)-hydroxy-tetradecaenoic acid. | 2011 | Curr. Microbiol. | pmid:20509029 |
| Liu SJ et al. | Effect of ruminal pulse dose of polyunsaturated fatty acids on ruminal microbial populations and duodenal flow and milk profiles of fatty acids. | 2011 | J. Dairy Sci. | pmid:21605768 |
| Popescu FD et al. | Effects of season and reproductive state on lipid intake and fatty acid composition of gastrointestinal tract contents in the European hare. | 2011 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:21328065 |
| Lee MJ et al. | The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia. | 2011 | Mol. Cells | pmid:21331775 |
| Cunnane SC and Guesnet P | Linoleic acid recommendations--A house of cards. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21963263 |
| P Wrobel T et al. | Imaging of lipids in atherosclerotic lesion in aorta from ApoE/LDLR-/- mice by FT-IR spectroscopy and Hierarchical Cluster Analysis. | 2011 | Analyst | pmid:22007352 |
| Lebold KM et al. | Vitamin E deficiency decreases long-chain PUFA in zebrafish (Danio rerio). | 2011 | J. Nutr. | pmid:22013196 |
| Nishioka N et al. | Linoleic acid enhances angiogenesis through suppression of angiostatin induced by plasminogen activator inhibitor 1. | 2011 | Br. J. Cancer | pmid:22015554 |
| Alimi H et al. | Evaluation of antioxidant and antiulcerogenic activities of Opuntia ficus indica f. inermis flowers extract in rats. | 2011 | Environ. Toxicol. Pharmacol. | pmid:22004960 |
| Strandvik B | The omega-6/omega-3 ratio is of importance! | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21945460 |
| Espinosa-Neira R et al. | Linoleic acid induces an EMT-like process in mammary epithelial cells MCF10A. | 2011 | Int. J. Biochem. Cell Biol. | pmid:21945809 |
| Mahmmoud YA and Christensen SB | Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E(2)P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump. | 2011 | Biochim. Biophys. Acta | pmid:21767529 |
| Khadake R et al. | Functional and bioinformatic characterisation of sequence variants of Fad3 gene from flax. | 2011 | J. Sci. Food Agric. | pmid:21769878 |
| Banta JP et al. | Effects of prepartum supplementation of linoleic and mid-oleic sunflower seed on cow performance, cow reproduction, and calf performance from birth through slaughter, and effects on intake and digestion in steers. | 2011 | J. Anim. Sci. | pmid:21788431 |
| KonÄić MZ et al. | Antiradical, chelating and antioxidant activities of hydroxamic acids and hydroxyureas. | 2011 | Molecules | pmid:21788931 |
| Ramsden CE et al. | All PUFAs are not created equal: absence of CHD benefit specific to linoleic acid in randomized controlled trials and prospective observational cohorts. | 2011 | World Rev Nutr Diet | pmid:21865817 |
| Okuyama H et al. | New Cholesterol Guidelines for Longevity (2010). | 2011 | World Rev Nutr Diet | pmid:21865826 |
| Legrand P et al. | Update of French nutritional recommendations for fatty acids. | 2011 | World Rev Nutr Diet | pmid:21865827 |
| Khan AA et al. | Synthesis and characterization of novel PUFA esters exhibiting potential anticancer activities: an in vitro study. | 2011 | Eur J Med Chem | pmid:21868138 |
| Arciniega JC et al. | Effects of free fatty acids on meibomian lipid films. | 2011 | Exp. Eye Res. | pmid:21718696 |
| Yang Y et al. | Synthesis and antioxidant capacities of hydroxyl derivatives of cinnamoylphenethylamine in protecting DNA and scavenging radicals. | 2011 | Free Radic. Res. | pmid:21128731 |
| Hubert DJ et al. | In vitro hepatoprotective and antioxidant activities of crude extract and isolated compounds from Ficus gnaphalocarpa. | 2011 | Inflammopharmacology | pmid:21088994 |
| Jin G et al. | Crude lipoxygenase from pig muscle: partial characterization and interactions of temperature, NaCl and pH on its activity. | 2011 | Meat Sci. | pmid:21093161 |
| Du YZ et al. | Linoleic acid-grafted chitosan oligosaccharide micelles for intracellular drug delivery and reverse drug resistance of tumor cells. | 2011 | Int. J. Biol. Macromol. | pmid:21093477 |
| You Q et al. | Purification, immobilization and characterization of linoleic acid isomerase on modified palygorskite. | 2011 | Bioprocess Biosyst Eng | pmid:21340675 |
| Rybicka M et al. | Comparative effects of conjugated linoleic acid (CLA) and linoleic acid (LA) on the oxidoreduction status in THP-1 macrophages. | 2011 | J. Agric. Food Chem. | pmid:21391598 |
| Rakib MA et al. | Preventive effect of t,t-conjugated linoleic acid on 12-O-tetradecanoylphorbol-13-acetate-induced inhibition of gap junctional intercellular communication in human mammary epithelial MCF-10A cells. | 2011 | J. Agric. Food Chem. | pmid:21391601 |
| Tuei VC et al. | Effects of human serum albumin complexed with free fatty acids on cell viability and insulin secretion in the hamster pancreatic β-cell line HIT-T15. | 2011 | Life Sci. | pmid:21396379 |
| Mihaljević B et al. | Linoleic acid peroxidation vs. isomerization: a biomimetic model of free radical reactivity in the presence of thiols. | 2011 | Org. Biomol. Chem. | pmid:21442126 |
| Blum JL et al. | Profiling of fatty acids released during calcium-induced mitochondrial permeability transition in isolated rabbit kidney cortex mitochondria. | 2011 | Toxicol In Vitro | pmid:21443943 |
| Conforti F et al. | Correlation between environmental factors, chemical composition, and antioxidative properties of caper species growing wild in Calabria (South Italy). | 2011 | Chem. Biodivers. | pmid:21404435 |
| Serratosa MP et al. | Changes in hydrophilic and lipophilic antioxidant activity in relation to their phenolic composition during the chamber drying of red grapes at a controlled temperature. | 2011 | J. Agric. Food Chem. | pmid:21319807 |
| Alloatti A and Uttaro AD | Highly specific methyl-end fatty-acid desaturases of trypanosomatids. | 2011 | Mol. Biochem. Parasitol. | pmid:20974196 |
| Figueras M et al. | Effects of eicosapentaenoic acid (EPA) treatment on insulin sensitivity in an animal model of diabetes: improvement of the inflammatory status. | 2011 | Obesity (Silver Spring) | pmid:20885391 |
| Konkel A and Schunck WH | Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids. | 2011 | Biochim. Biophys. Acta | pmid:20869469 |
| Liou AP et al. | The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin. | 2011 | Gastroenterology | pmid:20955703 |
| Perona JS et al. | Olive oil phenols modulate the triacylglycerol molecular species of human very low-density lipoprotein. A randomized, crossover, controlled trial. | 2011 | Metab. Clin. Exp. | pmid:20934731 |
| Mariutto M et al. | The elicitation of a systemic resistance by Pseudomonas putida BTP1 in tomato involves the stimulation of two lipoxygenase isoforms. | 2011 | BMC Plant Biol. | pmid:21294872 |
| Pan Z et al. | Effects of linoleate on cell viability and lipid metabolic homeostasis in goose primary hepatocytes. | 2011 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:21295151 |
| Tsubura A et al. | Anticancer effects of garlic and garlic-derived compounds for breast cancer control. | 2011 | Anticancer Agents Med Chem | pmid:21269259 |
| White HM et al. | Differential regulation of bovine pyruvate carboxylase promoters by fatty acids and peroxisome proliferator-activated receptor-α agonist. | 2011 | J. Dairy Sci. | pmid:21700028 |
| Siddique BM et al. | Chemical composition and antioxidant properties of candlenut oil extracted by supercritical CO2. | 2011 | J. Food Sci. | pmid:22417332 |
| Chen HH and Chiu TH | Phytochemicals characterization of solvent extracts from taro-scented japonica rice bran. | 2011 | J. Food Sci. | pmid:22417350 |
| Turk HF et al. | Linoleic acid and butyrate synergize to increase Bcl-2 levels in colonocytes. | 2011 | Int. J. Cancer | pmid:20232381 |