Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Nerve Degeneration D009410 53 associated lipids
Onchocerciasis D009855 1 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Parkinson Disease D010300 53 associated lipids
Pellagra D010383 1 associated lipids
Peritoneal Neoplasms D010534 16 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Hamazaki T and Okuyama H The Japan Society for Lipid Nutrition recommends to reduce the intake of linoleic acid. A review and critique of the scientific evidence. 2003 World Rev Nutr Diet pmid:14579687
Simopoulos AP Evolutionary aspects of the dietary omega-6:omega-3 fatty acid ratio: medical implications. 2009 World Rev Nutr Diet pmid:19696523
Watkins BA et al. Designed eggs containing conjugated linoleic acids and omega-3 polyunsaturated fatty acids. 2001 World Rev Nutr Diet pmid:11545041
Bibus DM and Stitt PA Metabolism of alpha-linolenic acid from flaxseed in dogs. 1998 World Rev Nutr Diet pmid:9648515
Okuyama H et al. Omega3 fatty acids effectively prevent coronary heart disease and other late-onset diseases--the excessive linoleic acid syndrome. 2007 World Rev Nutr Diet pmid:17167282
Okuyama H et al. Why isn't the causal relationship between linoleic acid and mortalities from coronary heart disease and stroke revealed by clinical studies? 2007 World Rev Nutr Diet pmid:17167283
Okuyama H et al. Mechanisms by which dietary fats affect coronary heart disease mortality. 2007 World Rev Nutr Diet pmid:17167284
Zheng HF et al. Effects of unsaturated fatty acids on calcium-activated potassium current in gastric myocytes of guinea pigs. 2005 World J. Gastroenterol. pmid:15655819
Chen BQ et al. Effects of c9,t11-conjugated linoleic acid on adhesion of human gastric carcinoma cell line SGC-7901. 2004 World J. Gastroenterol. pmid:15133841
Chen BQ et al. Inhibition of conjugated linoleic acid on mouse forestomach neoplasia induced by benzo (a) pyrene and chemopreventive mechanisms. 2003 World J. Gastroenterol. pmid:12508349
Brouwer DA et al. The dietary fatty acids of patients with coronary artery disease and controls in Curaçao. Implications for primary and secondary prevention. 1997 West Indian Med J pmid:9260535
Xue Y et al. [Effects of conjugated linoleic acid on the metastasis of mouse melanoma B16-MB]. 2001 Wei Sheng Yan Jiu pmid:11255760
Lu WH et al. [Screening and identification of a strain for hydroxylation of nicotinic acid]. 2005 Wei Sheng Wu Xue Bao pmid:15847152
Moon C et al. Modeling sulfate removal by inhibited mesophilic mixed anaerobic communities using a statistical approach. 2013 Water Res. pmid:23466036
Markov KhM et al. [Effect of dietary linoleic acid on the platelet aggregation, fatty acid composition of platelet phospholipids and synthesis of platelet prostaglandins in rats]. 1988 Jul-Aug Vopr. Med. Khim. pmid:3195130
Bondarenko LB et al. [Effect of 1,25-dihydroxyvitamin D3 on 15-lipoxygenase activity]. 1995 May-Jun Vopr. Med. Khim. pmid:8585174
Markov KhM and Kucherenko AG [Effect of diets with various contents of linoleic acid on the prostaglandin system in the rat kidney]. 1988 Mar-Apr Vopr. Med. Khim. pmid:3400199
ONDREICHKA R et al. [CHANGES IN THE CHEMICAL AND PHYSICAL PROPERTIES OF LARD AND BUTTER DURING HEATING]. 1963 Nov-Dec Vopr Pitan pmid:14149605
Martinchik AN [Nutritional value of sesame seeds]. 2011 Vopr Pitan pmid:21842753
Atrokhov VV and Markov KhM [Influence of rations with various linoleic acid contents on the fatty acid composition of phospholipids in blood platelets of rats]. 1987 Sep-Oct Vopr Pitan pmid:2894094