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Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes. |
1998 |
J. Pharmacol. Exp. Ther. |
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(Carboxyalkyl)pyrroles in human plasma and oxidized low-density lipoproteins. |
1997 |
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Oxygen concentration determines regiospecificity in soybean lipoxygenase-1 reaction via a branched kinetic scheme. |
1998 |
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Stereochemistry of oxygenation of linoleic acid catalyzed by prostaglandin-endoperoxide H synthase-2. |
1998 |
Arch. Biochem. Biophys. |
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Colquhoun A and Curi R |
Regulation of tumour cell fatty acid oxidation by n-6 polyunsaturated fatty acids. |
1997 |
Biochem. Soc. Trans. |
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Inhibition of Fe(II) catalyzed linoleic acid oxidation and DNA damage by phosvitin. |
1997 |
Mol. Cell. Biochem. |
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Peroxisomal beta-oxidation of polyunsaturated fatty acids in Saccharomyces cerevisiae: isocitrate dehydrogenase provides NADPH for reduction of double bonds at even positions. |
1998 |
EMBO J. |
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Implication of hydrogen peroxide generation and apoptosis in the neoplastic transformation of mouse fibroblasts overexpressing peroxisomal fatty acyl-CoA oxidase. |
1998 |
Int. J. Oncol. |
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Modulation of K+ channels by arachidonic acid in T84 cells. II. Activation of a Ca(2+)-independent K+ channel. |
1998 |
Am. J. Physiol. |
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Safflower oil consumption does not increase plasma conjugated linoleic acid concentrations in humans. |
1998 |
Am. J. Clin. Nutr. |
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Linoleic acid induces relaxation and hyperpolarization of the pig coronary artery. |
1998 |
Hypertension |
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Role of ceramide 1 in the molecular organization of the stratum corneum lipids. |
1998 |
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Low levels of linoleic acid in plasma total lipids of HIV-1 seropositive children. |
1998 |
J Am Coll Nutr |
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Calcium ions potentiate lipoxygenase activity of cytochrome c at the physiological pH. |
1998 |
Biochem. Biophys. Res. Commun. |
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A diet rich in walnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic subjects. |
1998 |
Eur J Clin Nutr |
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Unsaturated fatty acids alter the insulin secretion response of the islets of Langerhans in vitro. |
1997 |
Diabetes Res. Clin. Pract. |
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Modulation of the transient outward current in adult rat ventricular myocytes by polyunsaturated fatty acids. |
1998 |
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Effect of cis-unsaturated fatty acids on Meth-A ascitic tumour cells in vitro and in vivo. |
1998 |
Cancer Lett. |
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Effects of chain length and unsaturation of fatty acid mixtures infused into the abomasum of lactating dairy cows. |
1998 |
J. Dairy Sci. |
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Fatty acids and brain peptides. |
1998 |
Peptides |
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Relationship between birth weight of newborns and unsaturated fatty acid(n-3) proportions in their blood serum. |
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Physiol Res |
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Effects of nitric oxide synthase inhibition on phospholipid fatty acid composition of brown adipose tissue. |
1997 |
Jpn. J. Physiol. |
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Interactions between dietary fat type and xylanase supplementation when rye-based diets are fed to broiler chickens 2. Performance, nutrient digestibility and the fat-soluble vitamin status of livers. |
1997 |
Br. Poult. Sci. |
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Retinoic acid-dependent stimulation of 2,2'-azobis(2-amidinopropane)-initiated autoxidation of linoleic acid in sodium dodecyl sulfate micelles: a novel prooxidant effect of retinoic acid. |
1998 |
Chem. Res. Toxicol. |
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Jiang WG et al. |
The effects of n-6 polyunsaturated fatty acids on the expression of nm-23 in human cancer cells. |
1998 |
Br. J. Cancer |
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Alpha- and beta- alkyl-substituted eicosapentaenoic acids: incorporation into phospholipids and effects on prostaglandin H synthase and 5-lipoxygenase. |
1998 |
Biochem. Pharmacol. |
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Böhmer S et al. |
Oxidation of phenanthrene by a fungal laccase in the presence of 1-hydroxybenzotriazole and unsaturated lipids. |
1998 |
Biochem. Biophys. Res. Commun. |
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Regulation of tight junction permeability and occludin expression by polyunsaturated fatty acids. |
1998 |
Biochem. Biophys. Res. Commun. |
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Factors affecting events during oxidation of low density lipoprotein: correlation of multiple parameters of oxidation. |
1997 |
Free Radic. Res. |
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Possible mechanisms for the differential effects of high linoleate safflower oil and high alpha-linolenate perilla oil diets on platelet-activating factor production by rat polymorphonuclear leukocytes. |
1997 |
J Lipid Mediat Cell Signal |
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Protective effect of linoleic acid on IFN gamma-induced cellular injury in primary culture hepatocytes. |
1998 |
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Prevention of preeclampsia by linoleic acid and calcium supplementation: a randomized controlled trial. |
1998 |
Obstet Gynecol |
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Anticonvulsant effect of polyunsaturated fatty acids in rats, using the cortical stimulation model. |
1998 |
Eur. J. Pharmacol. |
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Fatty acids inhibit adrenocorticotropin-induced adrenal steroidogenesis. |
1998 |
Horm. Metab. Res. |
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Oxidized cholesterol in oxidized low density lipoprotein may be responsible for the inhibition of LPS-induced nitric oxide production in macrophages. |
1998 |
Atherosclerosis |
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Camacho M et al. |
IL-1 increases the ability of human endothelial cells to transform linoleic acid into monohydroxy-isomers and their incorporation into cell lipids. |
1997 |
Adv. Exp. Med. Biol. |
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Impairment in the fatty acid composition of keloids. |
1997 |
Adv. Exp. Med. Biol. |
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Linoleic acid levels in cutaneous tumors with different growth patterns as an additional sensitive diagnostic feature. |
1997 |
Adv. Exp. Med. Biol. |
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The importance of linoleic acid in the total fatty acid compositions of benign and malignant neuroglial tumors. |
1997 |
Adv. Exp. Med. Biol. |
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Identification and characterization of several forms of phospholipase A2 in mouse epidermal keratinocytes. |
1998 |
J. Lipid Res. |
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Pathophysiologic studies of experimental chronic pancreatitis in rats induced by injection of zein-oleic acid-linoleic acid solution into the pancreatic duct. |
1998 |
Pancreas |
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Factor VIIa response to a fat-rich meal does not depend on fatty acid composition: a randomized controlled trial. |
1998 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:9555866
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Absorption and fluorescence spectra of polyene antibiotics in the presence of human serum albumin. |
1998 |
Biochem. Mol. Biol. Int. |
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Mechanisms of androgen induction of sebocyte differentiation. |
1998 |
Dermatology (Basel) |
pmid:9557223
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Akamatsu H and Horio T |
The possible role of reactive oxygen species generated by neutrophils in mediating acne inflammation. |
1998 |
Dermatology (Basel) |
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Activation of the potato plant uncoupling mitochondrial protein inhibits reactive oxygen species generation by the respiratory chain. |
1998 |
FEBS Lett. |
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Dietary methionine level affects linoleic acid metabolism through phosphatidylethanolamine N-methylation in rats. |
1998 |
Lipids |
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Effect of continuous enteral medium-chain fatty acid infusion on lipid metabolism in rats. |
1998 |
Lipids |
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Bisallylic hydroxylation of linoleic and arachidonic acids by adult and fetal human liver microsomes and a comparison with human recombinant cytochromes P450. |
1997 |
Adv. Exp. Med. Biol. |
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Effect of linoleic acid supplements on vessel wall hyperplasia in rabbits. |
1997 |
Adv. Exp. Med. Biol. |
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Brister SJ and Buchanan MR |
Effects of linoleic acid and/or marine fish oil supplements on vessel wall thromboresistance in patients undergoing cardiac surgery. |
1997 |
Adv. Exp. Med. Biol. |
pmid:9561151
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Effects of linoleic acid supplements on atopic dermatitis. |
1997 |
Adv. Exp. Med. Biol. |
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The importance of linoleic acid metabolites in cancer metastasis and in the synthesis and actions of 13-HODE. |
1997 |
Adv. Exp. Med. Biol. |
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Modulation of learning and neuronal membrane composition in the rat by essential fatty acid preparation: time-course analysis. |
1998 |
Neurochem. Res. |
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Effects of supplementation with unsaturated fatty acids on plasma and membrane lipid composition and platelet function in patients with cirrhosis and defective aggregation. |
1998 |
J. Hepatol. |
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Dietary fatty acid sources affect conjugated linoleic acid concentrations in milk from lactating dairy cows. |
1998 |
J. Nutr. |
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Changes in expression of 15-lipoxygenase and prostaglandin-H synthase during differentiation of human tracheobronchial epithelial cells. |
1998 |
Am. J. Respir. Cell Mol. Biol. |
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Identification of non-heme diiron proteins that catalyze triple bond and epoxy group formation. |
1998 |
Science |
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Manganese lipoxygenase. Discovery of a bis-allylic hydroperoxide as product and intermediate in a lipoxygenase reaction. |
1998 |
J. Biol. Chem. |
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Peterson DB |
Long-chain fatty acids and cardiovascular disease risk in non-insulin-dependent diabetes. |
1998 |
Nutrition |
pmid:9583379
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Kambayashi Y et al. |
Preferential hydrolysis of oxidized phosphatidylcholine in cholesterol-containing phosphatidylcholine liposome by phospholipase A2. |
1998 |
Biochem. Biophys. Res. Commun. |
pmid:9588178
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Kwan KY et al. |
Inhibitory effect of linoleic acid on chain elongation and desaturation of 18:2 c,t isomers in lactating and neonatal rats. |
1998 |
Lipids |
pmid:9590629
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Egashira Y et al. |
Dietary linoleic acid alters alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), a key enzyme of niacin synthesis from tryptophan, in the process of protein expression in rat liver. |
1998 |
J. Nutr. Sci. Vitaminol. |
pmid:9591240
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Dokko RC et al. |
Cellular uptake of stearic, oleic, linoleic, and linolenic acid and their effects on synthesis and secretion of lipids in Hep-G2 cells. |
1998 |
Int. J. Biochem. Cell Biol. |
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Fatty acids induce release of Ca2+ from acidosomal stores and activate capacitative Ca2+ entry in Dictyostelium discoideum. |
1998 |
Biochem. J. |
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Geetha T et al. |
Effect of triterpenes from Crataeva nurvala stem bark on lipid peroxidation in adjuvant induced arthritis in rats. |
1998 |
Pharmacol. Res. |
pmid:9602466
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Inhibitory effects of n-3 polyunsaturated fatty acids on sigmoid colon cancer transformants. |
1998 |
J. Gastroenterol. |
pmid:9605950
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Kouba M and Mourot J |
Effect of a high linoleic acid diet on delta 9-desaturase activity, lipogenesis and lipid composition of pig subcutaneous adipose tissue. |
1998 Jan-Feb |
Reprod. Nutr. Dev. |
pmid:9606747
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Kleinfeld AM et al. |
Transport of long-chain native fatty acids across human erythrocyte ghost membranes. |
1998 |
Biochemistry |
pmid:9609694
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Das I and Khan NS |
Increased arachidonic acid induced platelet chemiluminescence indicates cyclooxygenase overactivity in schizophrenic subjects. |
1998 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:9610837
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Kikuchi S et al. |
Modulation of eosinophil chemotactic activities to leukotriene B4 by n-3 polyunsaturated fatty acids. |
1998 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:9610849
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Ohnishi M et al. |
Inhibition in vitro linoleic acid peroxidation and haemolysis by caffeoyltryptophan. |
1998 |
Phytochemistry |
pmid:9611825
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Liu KL and Belury MA |
Conjugated linoleic acid reduces arachidonic acid content and PGE2 synthesis in murine keratinocytes. |
1998 |
Cancer Lett. |
pmid:9619853
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Emken EA et al. |
Effect of dietary arachidonic acid on metabolism of deuterated linoleic acid by adult male subjects. |
1998 |
Lipids |
pmid:9625594
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Battu S et al. |
Linoleic acid peroxidation by Solanum tuberosum lipoxygenase was activated in the presence of human 5-lipoxygenase-activating protein. |
1998 |
Biochim. Biophys. Acta |
pmid:9630716
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Mizushina Y et al. |
An ergosterol peroxide, a natural product that selectively enhances the inhibitory effect of linoleic acid on DNA polymerase beta. |
1998 |
Biol. Pharm. Bull. |
pmid:9635497
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Hughes RK et al. |
Characterization of authentic recombinant pea-seed lipoxygenases with distinct properties and reaction mechanisms. |
1998 |
Biochem. J. |
pmid:9639559
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Iwase H et al. |
Formation of keto and hydroxy compounds of linoleic acid in submitochondrial particles of bovine heart. |
1998 |
Free Radic. Biol. Med. |
pmid:9641268
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Murthy S et al. |
13-hydroxy octadecadienoic acid (13-HODE) inhibits triacylglycerol-rich lipoprotein secretion by CaCo-2 cells. |
1998 |
J. Lipid Res. |
pmid:9643357
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Aarsland A and Wolfe RR |
Hepatic secretion of VLDL fatty acids during stimulated lipogenesis in men. |
1998 |
J. Lipid Res. |
pmid:9643360
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Dailly E et al. |
Chain-breaking antioxidants and ferriheme-bound drugs are synergistic inhibitors of erythrocyte membrane peroxidation. |
1998 |
Free Radic. Res. |
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Kagan VE et al. |
Plasma membrane NADH-coenzyme Q0 reductase generates semiquinone radicals and recycles vitamin E homologue in a superoxide-dependent reaction. |
1998 |
FEBS Lett. |
pmid:9645471
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Bibus DM and Stitt PA |
Metabolism of alpha-linolenic acid from flaxseed in dogs. |
1998 |
World Rev Nutr Diet |
pmid:9648515
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Yazu K et al. |
Mechanism of lower oxidizability of eicosapentaenoate than linoleate in aqueous micelles. II. Effect of antioxidants. |
1998 |
Lipids |
pmid:9655375
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Ohhashi K et al. |
Effect of replacing a high linoleate oil with a low linoleate, high alpha-linolenate oil, as compared with supplementing EPA or DHA, on reducing lipid mediator production in rat polymorphonuclear leukocytes. |
1998 |
Biol. Pharm. Bull. |
pmid:9657037
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Antonova SI |
[The dynamics of the secretion of linoleic acid as a component of the lipid classes with milk and their metabolism in the body of cows]. |
1998 Apr-Jun |
Usp Fiziol Nauk |
pmid:9659686
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Scimeca JA |
Toxicological evaluation of dietary conjugated linoleic acid in male Fischer 344 rats. |
1998 |
Food Chem. Toxicol. |
pmid:9662414
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Erickson KL |
Is there a relation between dietary linoleic acid and cancer of the breast, colon, or prostate? |
1998 |
Am. J. Clin. Nutr. |
pmid:9665090
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Zock PL and Katan MB |
Linoleic acid intake and cancer risk: a review and meta-analysis. |
1998 |
Am. J. Clin. Nutr. |
pmid:9665108
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Pitchumoni S et al. |
Reoxygenation injury affects isolated islet response to fatty acid stimulation. |
1998 |
Metab. Clin. Exp. |
pmid:9667226
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Cesano A et al. |
Opposite effects of linoleic acid and conjugated linoleic acid on human prostatic cancer in SCID mice. |
1998 May-Jun |
Anticancer Res. |
pmid:9673351
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Senzaki H et al. |
Dietary effects of fatty acids on growth and metastasis of KPL-1 human breast cancer cells in vivo and in vitro. |
1998 May-Jun |
Anticancer Res. |
pmid:9673380
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Guarini P et al. |
Effects of dietary fish oil and soy phosphatidylcholine on neutrophil fatty acid composition, superoxide release, and adhesion. |
1998 |
Inflammation |
pmid:9675609
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Osakabe N et al. |
The antioxidative substances in cacao liquor. |
1998 |
J. Nutr. Sci. Vitaminol. |
pmid:9675711
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Kelly ML et al. |
Effect of intake of pasture on concentrations of conjugated linoleic acid in milk of lactating cows. |
1998 |
J. Dairy Sci. |
pmid:9684170
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Demmelmair H et al. |
Metabolism of U13C-labeled linoleic acid in lactating women. |
1998 |
J. Lipid Res. |
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Kang LT and Vanderhoek JY |
Mono (S) hydroxy fatty acids: novel ligands for cytosolic actin. |
1998 |
J. Lipid Res. |
pmid:9684751
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Kato M et al. |
Reactivity of soybean lipoxygenase-1 to linoleic acid entrapped in phosphatidylcholine vesicles. |
1998 |
J. Biochem. |
pmid:9685717
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Fungwe TV et al. |
Fatty acids modulate lecithin:cholesterol acyltransferase secretion independently of effects on triglyceride secretion in primary rat hepatocytes. |
1998 |
J. Nutr. |
pmid:9687543
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Letawe C et al. |
Digital image analysis of the effect of topically applied linoleic acid on acne microcomedones. |
1998 |
Clin. Exp. Dermatol. |
pmid:9692305
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