Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Meningeal Neoplasms D008577 5 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Aortic Diseases D001018 11 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Atherosclerosis D050197 85 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Insulin Resistance D007333 99 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Hepatitis C, Chronic D019698 12 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Buchanan MR et al. 13-Hydroxyoctadecadienoic acid is the vessel wall chemorepellant factor, LOX. 1985 J. Biol. Chem. pmid:3934168
Margetts BM et al. Blood pressure and dietary polyunsaturated and saturated fats: a controlled trial. 1985 Clin. Sci. pmid:3905211
Allen RE et al. A serum-free medium that supports the growth of cultured skeletal muscle satellite cells. 1985 In Vitro Cell. Dev. Biol. pmid:3905759
Carroll KK Dietary fat in relation to mammary carcinogenesis. 1985 Int. Symp. Princess Takamatsu Cancer Res. Fund pmid:3916197
Ip C et al. Requirement of essential fatty acid for mammary tumorigenesis in the rat. 1985 Cancer Res. pmid:3921234
Stumpf DA The inherited ataxias. 1985 Neurol Clin pmid:3921817
Yoshikawa H et al. Potentiation of antitumor effect of bleomycin by lipid-surfactant mixed micelles. I. In vivo and tumor-neutralizing activity against mouse Ehrlich ascites tumor and rat ascites hepatoma AH66. 1985 J. Pharmacobio-dyn. pmid:2411907
Demant EJ and Wassermann K Doxorubicin induced alterations in lipid metabolism of cultured myocardial cells. 1985 Biochem. Pharmacol. pmid:4004891
Robinson M et al. Acylation of lysophospholipids by rabbit alveolar macrophages. Specificities of CoA-dependent and CoA-independent reactions. 1985 J. Biol. Chem. pmid:4008481
McMaster JD et al. Incorporation in vitro of 14C fatty acids into bovine sebaceous gland and dermal lipids. 1985 Res. Vet. Sci. pmid:4012036
Howard-Williams J et al. Polyunsaturated fatty acids and diabetic retinopathy. 1985 Br J Ophthalmol pmid:3965024
Montalto MB et al. Nutrient intakes of formula-fed infants and infants fed cow's milk. 1985 Pediatrics pmid:3969338
Reid JC and Husbands DR Oxidative metabolism of long-chain fatty acids in mitochondria from sheep and rat liver. Evidence that sheep conserve linoleate by limiting its oxidation. 1985 Biochem. J. pmid:3977825
Vergroesen AJ Effects of dietary lipid composition on serum lipoproteins. 1985 Prog. Clin. Biol. Res. pmid:3903769
Noble RC et al. Synthesis of C20 and C22 polyunsaturated fatty acids by the placenta of the sheep. 1985 Biol. Neonate pmid:4027296
Goldstein R et al. Increased maternal-fetal transport of fat in diabetes assessed by polyunsaturated fatty acid content in fetal lipids. 1985 Biol. Neonate pmid:4027297
Jett M et al. Metabolic fate of liposomal phosphatidylinositol in murine tumor cells: implications for the mechanism of tumor cell cytotoxicity. 1985 Cancer Res. pmid:4027970
Isseroff RR et al. Alterations in fatty acid composition of murine keratinocytes with in vitro cultivation. 1985 J. Invest. Dermatol. pmid:3926903
Poisson JP Comparative in vivo and in vitro study of the influence of experimental diabetes on rat liver linoleic acid delta 6- and delta 5-desaturation. 1985 Enzyme pmid:3002783
Salzmann-Reinhardt U et al. Metabolism of polyunsaturated fatty acids by rabbit reticulocytes. 1985 Eur. J. Biochem. pmid:3933978
Hennig B et al. Exposure to free fatty acid increases the transfer of albumin across cultured endothelial monolayers. 1984 Sep-Oct Arteriosclerosis pmid:6477300
Reuter W and Heybey U [Dietary fat analysis--a contribution to the problem of nutrition and aging]. 1984 May-Jun Z Alternsforsch pmid:6087576
Grójec M and Kaleta Z The composition of fatty acids of the serum and erythrocytes after an alimentary cholesterol load. 1984 Mar-Apr Acta Physiol Pol pmid:6537129
Johnston DV and Marshall LA Dietary fat, prostaglandins and the immune response. 1984 Prog Food Nutr Sci pmid:6091179
Brush MG et al. Abnormal essential fatty acid levels in plasma of women with premenstrual syndrome. 1984 Am. J. Obstet. Gynecol. pmid:6091462
Singer P et al. Attenuation of high blood pressure by primrose oil, linseed oil and sunflowerseed oil in spontaneously hypertensive rats. 1984 Biomed. Biochim. Acta pmid:6097233
Dworkin RH et al. Linoleic acid and multiple sclerosis: a reanalysis of three double-blind trials. 1984 Neurology pmid:6387534
Singer P et al. Defective desaturation and elongation of n-6 and n-3 fatty acids in hypertensive patients. 1984 Prostaglandins Leukot Med pmid:6387718
Sohal RS et al. Relationship between lipofuscin granules and polyunsaturated fatty acids in the housefly, Musca domestica. 1984 Mech. Ageing Dev. pmid:6330462
Tarozzi G et al. Fatty acid composition of single brain structures following different alpha linolenate dietary supplementations. 1984 Acta Vitaminol. Enzymol. pmid:6098184
Sakaguchi M et al. Effect of dietary unsaturated and saturated fats on azoxymethane-induced colon carcinogenesis in rats. 1984 Cancer Res. pmid:6704963
Codde JP et al. Dissociation of effects of dietary fatty acids on blood pressure and prostanoid metabolism in Goldblatt hypertensive rats. 1984 J. Hypertens. pmid:6099384
Chen TC et al. Modulation of 1,25-dihydroxyvitamin D3 receptor by phospholipids and fatty acids. 1984 J. Lipid Res. pmid:6099395
Murphy MG Increasing membrane polyunsaturated fatty-acid content augments cyclic AMP formation and prostaglandin production in NIE-115 neuroblastoma. 1984 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:6099586
Mirouze J et al. [How is diabetic nutrition understood in 1984?]. 1984 Journ Annu Diabetol Hotel Dieu pmid:6100378
Frankel EN Chemistry of free radical and singlet oxidation of lipids. 1984 Prog. Lipid Res. pmid:6100997
Van Alstine JM and Brooks DE Cell membrane abnormality detected in erythrocytes from patients with multiple sclerosis by partition in two-polymer aqueous-phase systems. 1984 Clin. Chem. pmid:6199135
Laakso S Inhibition of lipid peroxidation by casein. Evidence of molecular encapsulation of 1,4-pentadiene fatty acids. 1984 Biochim. Biophys. Acta pmid:6419780
Benaim G et al. Different conformational states of the purified Ca2+-ATPase of the erythrocyte plasma membrane revealed by controlled trypsin proteolysis. 1984 J. Biol. Chem. pmid:6234313
Narce M and Poisson JP [In vitro study of delta 6- and delta 5-desaturations of linoleic and dihomo-gamma-linolenic acids during the development of arterial hypertension as a function of age in spontaneously hypertensive rats (SHR) as compared to normotensive rats (WKY)]. 1984 C. R. Seances Soc. Biol. Fil. pmid:6241017
Naegelen J et al. [Placental fatty acids in the guinea pig during pregnancy]. 1984 C. R. Seances Soc. Biol. Fil. pmid:6241019
Grossman S et al. Methylmercuric iodide modification of lipoxygenase-1. Effects on the anaerobic reaction and pigment bleaching. 1984 Biochim. Biophys. Acta pmid:6424722
Enig MG et al. Trans-unsaturated fatty acids in margarines and human subcutaneous fat in Israel. 1984 Hum Nutr Clin Nutr pmid:6086551
Baba A et al. Modulation by unsaturated fatty acids of norepinephrine- and adenosine-induced formation of cyclic AMP in brain slices. 1984 J. Neurochem. pmid:6315886
Booyens J et al. Some effects of linoleic acid and gamma-linolenic acid on the proliferation of human hepatoma cells in culture. 1984 S. Afr. Med. J. pmid:6324395
Simon I et al. Electron-spin resonance studies of lipid-modified microsomes from Friend erythroleukemia cells. 1984 Biochim. Biophys. Acta pmid:6326852
Manku MS et al. Essential fatty acids in the plasma phospholipids of patients with atopic eczema. 1984 Br. J. Dermatol. pmid:6329254
Schick PK et al. Arachidonate synthesis and uptake in isolated guinea-pig megakaryocytes and platelets. 1984 Biochim. Biophys. Acta pmid:6433984
Furukawa M et al. Studies on arachidonate 5-lipoxygenase of rat basophilic leukemia cells. 1984 Biochim. Biophys. Acta pmid:6089906
Inouye S Site-specific cleavage of double-strand DNA by hydroperoxide of linoleic acid. 1984 FEBS Lett. pmid:6430718
Ramesha CS and Thompson GA The mechanism of membrane response to chilling. Effect of temperature on phospholipid deacylation and reacylation reactions in the cell surface membrane. 1984 J. Biol. Chem. pmid:6430890
Kitagawa S et al. Activation of bovine platelets induced by long-chain unsaturated fatty acids at just below their lytic concentrations, and its mechanism. 1984 Biochim. Biophys. Acta pmid:6435686
Rüthrich HL et al. Perinatal linoleate deprivation impairs learning and memory in adult rats. 1984 Behav. Neural Biol. pmid:6539591
Balschun D et al. Chronobiologic and metabolic characterization of rats fed low or high linoleic acid diets. 1984 Biomed. Biochim. Acta pmid:6542778
Toda S et al. [Inhibitory effects of methanol extracts of crude drugs on the air oxidation of linoleic acid]. 1984 Yakugaku Zasshi pmid:6491877
Agnoli GC et al. [Relation between acute changes in diuresis and renal prostaglandins. I: Induced hypotonic polyuria]. 1984 Boll. Soc. Ital. Biol. Sper. pmid:6497992
Válek J et al. [Linoleic acid in patients with ischemic heart disease]. 1984 Vnitr Lek pmid:6506507
Reeves VB et al. Variations in plasma fatty acid concentrations during a one-year self-selected dietary intake study. 1984 Am. J. Clin. Nutr. pmid:6507356
Becker W Distribution of 14C after oral administration of [1-14C]linoleic acid in rats fed different levels of essential fatty acids. 1984 J. Nutr. pmid:6470826
Rogiers V et al. Abnormal fatty acid turnover in the phospholipids of the red blood cell membranes of cystic fibrosis patients (in vitro study). 1984 Pediatr. Res. pmid:6472942
Noble RC et al. Lipid composition of the bovine epidermis. 1984 Res. Vet. Sci. pmid:6473909
Heine RJ et al. The effect of dietary linoleic acid and pectin on lipoprotein and apolipoprotein A1 concentrations in rhesus monkeys. 1984 Ann. Nutr. Metab. pmid:6476785
Marzouki ZM and Coniglio JG The effects of hypophysectomy and testosterone treatment on the composition and metabolism of testicular lipids. 1984 Lipids pmid:6482683
Adam O and Wolfram G Effect of different linoleic acid intakes on prostaglandin biosynthesis and kidney function in man. 1984 Am. J. Clin. Nutr. pmid:6486083
Badwey JA et al. Effects of free fatty acids on release of superoxide and on change of shape by human neutrophils. Reversibility by albumin. 1984 J. Biol. Chem. pmid:6330088
Pratsch L et al. Interaction of fusogen substances with the erythrocyte membrane. 1984 Biomed. Biochim. Acta pmid:6487285
Jacobs JM and Jacobs NJ Effect of unsaturated fatty acids on protoporphyrinogen oxidation, a step in heme and chlorophyll synthesis in plant organelles. 1984 Biochem. Biophys. Res. Commun. pmid:6487324
Tanizawa H et al. Natural antioxidants. I. Antioxidative components of tea leaf (Thea sinensis L.). 1984 Chem. Pharm. Bull. pmid:6467480
Caponnetto A et al. [Essential fatty acids for ectodermic organs]. 1984 Boll. Soc. Ital. Biol. Sper. pmid:6518108
Tseng YL and Latham KR Iodothyronines: oxidative deiodination by hemoglobin and inhibition of lipid peroxidation. 1984 Lipids pmid:6708757
Caponnetto A et al. [Alpha-linolenic acid and its metabolic derivatives in the tissues of rats treated with CCl4]. 1984 Boll. Soc. Ital. Biol. Sper. pmid:6518109
Yorek MA et al. Comparative utilization of n-3 polyunsaturated fatty acids by cultured human Y-79 retinoblastoma cells. 1984 Biochim. Biophys. Acta pmid:6089899
MacDonald ML et al. Essential fatty acid requirements of cats: pathology of essential fatty acid deficiency. 1984 Am. J. Vet. Res. pmid:24049889
Sánchez J and Stumpf PK The effect of hypolipidemic drugs WY14643 and DH990, and lysophospholipids on the metabolism of oleate in plants. 1984 Arch. Biochem. Biophys. pmid:6696430
Arslan P et al. cis-Unsaturated fatty acids uncouple mitochondria and stimulate glycolysis in intact lymphocytes. 1984 Biochem. J. pmid:6696740
Chu CH et al. The activity of 3-hydroxyacyl-CoA epimerase is insufficient to account for the rate of linoleate oxidation in rat heart mitochondria. Evidence for a modified pathway of linoleate degradation. 1984 Biochem. Biophys. Res. Commun. pmid:6696754
Cherayil GD Sialic acid and fatty acid concentrations in lymphocytes, red blood cells and plasma from patients with multiple sclerosis. 1984 J. Neurol. Sci. pmid:6699649
El-Mallakh RS Treatment of acute lithium toxicity. 1984 Vet Hum Toxicol pmid:6702100
Alao SJ and Balnave D Growth and carcass composition of broilers fed sunflower oil and olive oil. 1984 Br. Poult. Sci. pmid:6733552
Stymne S and Stobart AK The biosynthesis of triacylglycerols in microsomal preparations of developing cotyledons of sunflower (Helianthus annuus L.). 1984 Biochem. J. pmid:6743281
Colard O et al. 1-Acyl-lysolecithin acyltransferase and synthesis of biliary lecithins in rat liver. 1984 Biochimie pmid:6743697
Huang YS et al. Effect of dietary depletion and repletion of linoleic acid on renal fatty acid composition and urinary prostaglandin excretion. 1984 Prostaglandins Leukot Med pmid:6593743
Margetts BM et al. Dietary fats and blood pressure. 1984 Aust N Z J Med pmid:6596055
Eyssen H and Verhulst A Biotransformation of linoleic acid and bile acids by Eubacterium lentum. 1984 Appl. Environ. Microbiol. pmid:6582800
Strong AM et al. Prostaglandin precursors in plasma phospholipids of patients with psoriasis: effects of treatment with coal tar. 1984 Prostaglandins Leukot Med pmid:6588390
Merzlyak MN and Kovrizhnih VA Lipid-phenolic radical adducts as a plausible mechanism of "plant ageing" pigment formation. 1984 Gen. Physiol. Biophys. pmid:6530137
Cunnane SC et al. Linoleic acid and arachidonic acid metabolism in human peripheral blood leucocytes: comparison with the rat. 1984 Br. J. Nutr. pmid:6422980
Curnutte JT et al. Studies on the mechanism of superoxide release from human neutrophils stimulated with arachidonate. 1984 J. Biol. Chem. pmid:6090448
Chapkin RS and Ziboh VA Inability of skin enzyme preparations to biosynthesize arachidonic acid from linoleic acid. 1984 Biochem. Biophys. Res. Commun. pmid:6439197
Koo SI and Ramlet JS Effect of dietary linoleic acid on the tissue levels of zinc and copper, and serum high density lipoprotein cholesterol. 1984 Atherosclerosis pmid:6712766
Harada H et al. Enhanced suppression of myocardial slow action potentials during hypoxia by free fatty acids. 1984 J. Mol. Cell. Cardiol. pmid:6716492
Grosch W and Laskawy G [Contribution of linoleic acid to the bitter taste of poppy seeds (Papaver somniferum)]. 1984 Z Lebensm Unters Forsch pmid:6720091
McMurchie EJ et al. Dietary-induced changes in the fatty acid composition of human cheek cell phospholipids: correlation with changes in the dietary polyunsaturated/saturated fat ratio. 1984 Am. J. Clin. Nutr. pmid:6720626
Iversen SA et al. Identification of a diene conjugated component of human lipid as octadeca-9,11-dienoic acid. 1984 FEBS Lett. pmid:6723989
Bruckner G et al. Essential fatty acid status and characteristics associated with colostrum-deprived gnotobiotic and conventional lambs. Growth, organ development, cell membrane integrity and factors associated with lower bowel function. 1984 J. Anim. Sci. pmid:6725155
Schafer E and Arnrich L Effects of dietary vitamin E on serum and pulmonary fatty acids and prostaglandins in rats fed excess linoleic acid. 1984 J. Nutr. pmid:6726476
Hagve TA and Christophersen BO Effect of dietary fats on arachidonic acid and eicosapentaenoic acid biosynthesis and conversion to C22 fatty acids in isolated rat liver cells. 1984 Biochim. Biophys. Acta pmid:6093889
Singer P et al. Age-dependent alterations of linoleic, arachidonic and eicosapentaenoic acids in renal cortex and medulla of spontaneously hypertensive rats. 1984 Prostaglandins pmid:6328578
Asakawa T et al. Ca2+-activated, fatty acid-dependent guanylate cyclase in synaptic plasma membranes and its requirement for Ca2+ and Mg-GTP in the activation. 1984 Adv. Exp. Med. Biol. pmid:6149673
Wood DA et al. Adipose tissue and platelet fatty acids and coronary heart disease in Scottish men. 1984 Lancet pmid:6146032