| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colitis | D003092 | 69 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Song E et al. | Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice. | 2014 | J Am Heart Assoc | pmid:24721803 |
| Reed S et al. | Dietary zinc deficiency affects blood linoleic acid: dihomo-γ-linolenic acid (LA:DGLA) ratio; a sensitive physiological marker of zinc status in vivo (Gallus gallus). | 2014 | Nutrients | pmid:24658588 |
| Bernhard W et al. | Plasma phospholipids indicate impaired fatty acid homeostasis in preterm infants. | 2014 | Eur J Nutr | pmid:24464176 |
| Hodson L et al. | Plasma and erythrocyte fatty acids reflect intakes of saturated and n-6 PUFA within a similar time frame. | 2014 | J. Nutr. | pmid:24225449 |
| Xu QY et al. | Metabolomic analysis of simvastatin and fenofibrate intervention in high-lipid diet-induced hyperlipidemia rats. | 2014 | Acta Pharmacol. Sin. | pmid:25220639 |
| Victoria FN et al. | Antioxidant and antidepressant-like activities of semi-synthetic α-phenylseleno citronellal. | 2014 | Eur. J. Pharmacol. | pmid:25218989 |
| Farvid MS et al. | Dietary linoleic acid and risk of coronary heart disease: a systematic review and meta-analysis of prospective cohort studies. | 2014 | Circulation | pmid:25161045 |
| Harris WS and Shearer GC | Omega-6 fatty acids and cardiovascular disease: friend, not foe? | 2014 | Circulation | pmid:25161044 |
| Saito HE et al. | Incorporation of exogenous fatty acids protects Enterococcus faecalis from membrane-damaging agents. | 2014 | Appl. Environ. Microbiol. | pmid:25128342 |
| Wu JH et al. | Circulating omega-6 polyunsaturated fatty acids and total and cause-specific mortality: the Cardiovascular Health Study. | 2014 | Circulation | pmid:25124495 |
| Phan CW et al. | Intrastrain comparison of the chemical composition and antioxidant activity of an edible mushroom, Pleurotus giganteus, and its potent neuritogenic properties. | 2014 | ScientificWorldJournal | pmid:25121118 |
| Purushothaman D et al. | Flaxseed oil supplementation alters the expression of inflammatory-related genes in dogs. | 2014 | Genet. Mol. Res. | pmid:25078588 |
| van Schalkwijk DB et al. | Dietary medium chain fatty acid supplementation leads to reduced VLDL lipolysis and uptake rates in comparison to linoleic acid supplementation. | 2014 | PLoS ONE | pmid:25049048 |
| Scalerandi MV et al. | Effect of conjugated linoleic acid mixtures and different edible oils in body composition and lipid regulation in mice. | 2014 | Nutr Hosp | pmid:24559004 |
| Asselin C et al. | Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure. | 2014 | Redox Biol | pmid:24494189 |
| Mouradian M et al. | Key roles for GRB2-associated-binding protein 1, phosphatidylinositol-3-kinase, cyclooxygenase 2, prostaglandin E2 and transforming growth factor alpha in linoleic acid-induced upregulation of lung and breast cancer cell growth. | 2014 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24374147 |
| Choi JI et al. | Development of microalga Scenedesmus dimorphus mutant with higher lipid content by radiation breeding. | 2014 | Bioprocess Biosyst Eng | pmid:24871276 |
| Wright CR and Setzer WN | Chemical composition of volatiles from Opuntia littoralis, Opuntia ficus-indica, and Opuntia prolifera growing on Catalina Island, California. | 2014 | Nat. Prod. Res. | pmid:24354326 |
| Bakır T et al. | Antioxidant/prooxidant effects of α-tocopherol, quercetin and isorhamnetin on linoleic acid peroxidation induced by Cu(II) and H2O2. | 2014 | Int J Food Sci Nutr | pmid:24152374 |
| Yavin E et al. | Metabolic conversion of intra-amniotically-injected deuterium-labeled essential fatty acids by fetal rats following maternal n-3 fatty acid deficiency. | 2014 | Biochim. Biophys. Acta | pmid:24960100 |
| Huang FC et al. | Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola. | 2014 | Appl. Environ. Microbiol. | pmid:24242247 |
| Bonferoni MC et al. | Ionic polymeric micelles based on chitosan and fatty acids and intended for wound healing. Comparison of linoleic and oleic acid. | 2014 | Eur J Pharm Biopharm | pmid:24384070 |
| Chevrot M et al. | Obesity interferes with the orosensory detection of long-chain fatty acids in humans. | 2014 | Am. J. Clin. Nutr. | pmid:24522446 |
| Barua P et al. | Seed oils from non-conventional sources in north-east India: potential feedstock for production of biodiesel. | 2014 | Nat. Prod. Res. | pmid:24483850 |
| Cho Y et al. | Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid docosahexaenoic acid and butyrate through promoter methylation. | 2014 | Exp. Biol. Med. (Maywood) | pmid:24495951 |
| Matthaus B and Özcan MM | Fatty acid and tocopherol contents of several soybean oils. | 2014 | Nat. Prod. Res. | pmid:24499198 |
| Dailey MJ et al. | Nutrient-specific feeding and endocrine effects of jejunal infusions in obese animals. | 2014 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:24452547 |
| Shen J et al. | A 13-lipoxygenase, TomloxC, is essential for synthesis of C5 flavour volatiles in tomato. | 2014 | J. Exp. Bot. | pmid:24453226 |
| Mulligan CM et al. | Inhibition of delta-6 desaturase reverses cardiolipin remodeling and prevents contractile dysfunction in the aged mouse heart without altering mitochondrial respiratory function. | 2014 | J. Gerontol. A Biol. Sci. Med. Sci. | pmid:24418793 |
| Paulsen SJ et al. | Expression of the fatty acid receptor GPR120 in the gut of diet-induced-obese rats and its role in GLP-1 secretion. | 2014 | PLoS ONE | pmid:24520357 |
| Mahendran Y et al. | Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes. | 2014 | Am. J. Clin. Nutr. | pmid:24153340 |
| Ogorodnikova AV et al. | Screening of divinyl ether synthase activity in nonphotosynthetic tissue of asparagales. | 2013 Mar-Apr | Dokl. Biochem. Biophys. | pmid:23657662 |
| Thomas CP et al. | Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis. | 2013 Feb-Mar | Chem. Phys. Lipids | pmid:23352713 |
| Ivan M et al. | Rumen fermentation and microbial population in lactating dairy cows receiving diets containing oilseeds rich in C-18 fatty acids. | 2013 | Br. J. Nutr. | pmid:22850225 |
| Alvheim AR et al. | Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice. | 2013 | Br. J. Nutr. | pmid:22883314 |
| Godinot N et al. | Activation of tongue-expressed GPR40 and GPR120 by non caloric agonists is not sufficient to drive preference in mice. | 2013 | Neuroscience | pmid:23831422 |
| Lai MC et al. | The natural PPAR agonist linoleic acid stimulated insulin release in the rat pancreas. | 2013 | J. Vet. Med. Sci. | pmid:23832628 |
| Kälber T et al. | Effect of feeding buckwheat and chicory silages on fatty acid profile and cheese-making properties of milk from dairy cows. | 2013 | J. Dairy Res. | pmid:23253429 |
| Gillingham LG et al. | Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition. | 2013 | Am. J. Clin. Nutr. | pmid:23221573 |
| Carro M et al. | Linoleic acid stimulates neutral lipid accumulation in lipid droplets of maturing bovine oocytes. | 2013 | Theriogenology | pmid:23273433 |
| Khan AA et al. | Anticancer efficacy of a novel propofol-linoleic acid-loaded escheriosomal formulation against murine hepatocellular carcinoma. | 2013 | Nanomedicine (Lond) | pmid:23311988 |
| Graves JP et al. | Characterization of four new mouse cytochrome P450 enzymes of the CYP2J subfamily. | 2013 | Drug Metab. Dispos. | pmid:23315644 |
| Carey AN et al. | The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells. | 2013 | Nutr Neurosci | pmid:23321679 |
| Guo J et al. | Selective transport of long-chain fatty acids by FAT/CD36 in skeletal muscle of broilers. | 2013 | Animal | pmid:23031491 |
| Kiernan M et al. | The effect of the in vitro supplementation of exogenous long-chain fatty acids on bovine sperm cell function. | 2013 | Reprod. Fertil. Dev. | pmid:23036717 |
| Han L et al. | Hydroxyl radical induced by lipid in Maillard reaction model system promotes diet-derived N(ε)-carboxymethyllysine formation. | 2013 | Food Chem. Toxicol. | pmid:23959106 |
| Aboshi T et al. | Biosynthesis of linoleic acid in Tyrophagus mites (Acarina: Acaridae). | 2013 | Insect Biochem. Mol. Biol. | pmid:23973745 |
| Hashim A et al. | Antioxidant and α -amylase inhibitory property of phyllanthus virgatus L.: an in vitro and molecular interaction study. | 2013 | Biomed Res Int | pmid:23957001 |
| Navarro-Guillén C et al. | Interaction between dietary levels of LC-PUFA and vegetable oil sources in Senegalese sole (Solea senegalensis) post-larvae: puzzling results suggesting complete biosynthesis pathway from C18 PUFA to DHA. | 2013 | Commun. Agric. Appl. Biol. Sci. | pmid:25141696 |
| Okada Y et al. | Trans fatty acids exacerbate dextran sodium sulphate-induced colitis by promoting the up-regulation of macrophage-derived proinflammatory cytokines involved in T helper 17 cell polarization. | 2013 | Clin. Exp. Immunol. | pmid:24028683 |