Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

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Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Cicatrix, Hypertrophic D017439 4 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Dermatitis, Phototoxic D017484 4 associated lipids
Hyperpigmentation D017495 11 associated lipids
Myocardial Stunning D017682 10 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Glucose Intolerance D018149 13 associated lipids
Circoviridae Infections D018173 2 associated lipids
Hypokinesia D018476 2 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Kharasch ED and Novak RF Mitoxantrone and ametantrone inhibit hydroperoxide-dependent initiation and propagation reactions in fatty acid peroxidation. 1985 J. Biol. Chem. pmid:2993283
Claeys M et al. Metabolic profile of linoleic acid in porcine leukocytes through the lipoxygenase pathway. 1985 Biochim. Biophys. Acta pmid:2996610
Cunnane SC et al. Essential fatty acids in the liver and adipose tissue of genetically obese mice: effect of supplemental linoleic and gamma-linolenic acids. 1985 Br. J. Nutr. pmid:2998443
Cunnane SC et al. Abnormal essential fatty acid composition of tissue lipids in genetically diabetic mice is partially corrected by dietary linoleic and gamma-linolenic acids. 1985 Br. J. Nutr. pmid:2998444
Narce M and Poisson JP [In vitro study of delta-6- and delta-5-desaturation of linoleic and dihomo-gamma-linolenic acids in WKY rats on a high-sodium diet]. 1985 C. R. Seances Soc. Biol. Fil. pmid:2939926
Hansen HS and Jensen B Essential function of linoleic acid esterified in acylglucosylceramide and acylceramide in maintaining the epidermal water permeability barrier. Evidence from feeding studies with oleate, linoleate, arachidonate, columbinate and alpha-linolenate. 1985 Biochim. Biophys. Acta pmid:3922424
Nugteren DH et al. Metabolism of linoleic acid and other essential fatty acids in the epidermis of the rat. 1985 Biochim. Biophys. Acta pmid:3922425
Allen RE et al. Effect of insulin and linoleic acid on satellite cell differentiation. 1985 J. Anim. Sci. pmid:3894312
Canfield LM et al. Anti-oxidant/pro-oxidant reactions of vitamin K. 1985 Biochem. Biophys. Res. Commun. pmid:3985964
Koletzko B et al. Fatty acid composition of plasma lipids in acrodermatitis enteropathica before and after zinc supplementation. 1985 Eur. J. Pediatr. pmid:3987733
Sugita A et al. [Serum long chain fatty acids in the patients with inflammatory bowel disease]. 1985 Nihon Shokakibyo Gakkai Zasshi pmid:3990036
Adam O et al. Prostaglandin formation and platelet aggregation during fasting and linoleic acid intake. 1985 Res Exp Med (Berl) pmid:3992060
Válek J et al. Serum linoleic acid and cardiovascular death in postinfarction middle-aged men. 1985 Atherosclerosis pmid:3994777
Tsuchida M et al. Fluorescent substances in mouse and human sera as a parameter of in vivo lipid peroxidation. 1985 Biochim. Biophys. Acta pmid:3995061
Bowser PA et al. Identification, isolation and characterization of epidermal lipids containing linoleic acid. 1985 Biochim. Biophys. Acta pmid:3995076
Demant EJ and Wassermann K Doxorubicin induced alterations in lipid metabolism of cultured myocardial cells. 1985 Biochem. Pharmacol. pmid:4004891
Robinson M et al. Acylation of lysophospholipids by rabbit alveolar macrophages. Specificities of CoA-dependent and CoA-independent reactions. 1985 J. Biol. Chem. pmid:4008481
Charnock JS et al. Altered levels of n-6/n-3 fatty acids in rat heart and storage fat following variable dietary intake of linoleic acid. 1985 Ann. Nutr. Metab. pmid:4051450
Charnock JS et al. Diet and cardiac arrhythmia: effects of lipids on age-related changes in myocardial function in the rat. 1985 Ann. Nutr. Metab. pmid:4051452
Takahashi K et al. Ester-exchange catalyzed by lipase modified with polyethylene glycol. 1985 Biochem. Biophys. Res. Commun. pmid:4052065
Hennig B et al. Exposure to fatty acid increases human low density lipoprotein transfer across cultured endothelial monolayers. 1985 Circ. Res. pmid:4053308
Hagve TA et al. Norflurazon--an inhibitor of essential fatty acid desaturation in isolated liver cells. 1985 Lipids pmid:4058269
Barclay LR et al. The antioxidant activity of alpha-tocopherol-bovine serum albumin complex in micellar and liposome autoxidations. 1985 J. Biol. Chem. pmid:4066696
Mathias MM and Dupont J Quantitative relationships between dietary linoleate and prostaglandin (eicosanoid) biosynthesis. 1985 Lipids pmid:4068908
Potter LM and McCarthy JP Varying fat and protein in diets of growing large white turkeys. 1985 Poult. Sci. pmid:4070128
Clark DL and Queener SF Effects of diabetes mellitus on renal fatty acid activation and desaturation. 1985 Biochem. Pharmacol. pmid:4074391
Giamalva D et al. A comparison of the rates of ozonation of biological antioxidants and oleate and linoleate esters. 1985 Biochem. Biophys. Res. Commun. pmid:4084297
Ford GL Semi-preparative isolation of crepenynic acid, a potential inhibitor of essential fatty acid metabolism. 1985 J. Chromatogr. pmid:4086624
Salo MK et al. Platelet aggregation in Finnish men and its relation to fatty acids in platelets, plasma and adipose tissue. 1985 Thromb. Haemost. pmid:4089791
Adam O et al. [The effect of linoleic acid intake on its concentration and resultant products in individual plasma lipids in humans]. 1985 Z Ernahrungswiss pmid:4096032
Rebello T and Watts DC Gastrocnemius muscle lipids in relation to diet in two mouse mutants, 129Re-dy and A2G-adr, with abnormal muscle function. 1985 J. Neurochem. pmid:3158720
Nordøy A et al. Effect of dietary (n--3) fatty acids on platelet function and lipid metabolism in rats. 1985 Biochim. Biophys. Acta pmid:2861854
Fusco AC et al. Schistosoma mansoni: eicosanoid production by cercariae. 1985 Exp. Parasitol. pmid:3917929
Levinson S et al. Comparison of intraluminal and intravenous mediators of colonic response to eating. 1985 Dig. Dis. Sci. pmid:3838089
Farrell PM et al. Fatty acid abnormalities in cystic fibrosis. 1985 Pediatr. Res. pmid:3918287
Kort WJ et al. Spontaneous tumor incidence in female brown Norway rats after lifelong diets high and low in linoleic acid. 1985 J. Natl. Cancer Inst. pmid:3856059
Cooke RJ et al. Safflower oil emulsion administration during parenteral nutrition in the preterm infant. 1. Effect on essential fatty acid status. 1985 J. Pediatr. Gastroenterol. Nutr. pmid:3930688
Stoeck M et al. Studies on the mechanism whereby cyclosporin A inhibits T-lymphocyte activation. 1985 Immunobiology pmid:2580777
Boberg M et al. Platelet fatty acid composition in relation to fatty acid composition in plasma and to serum lipoprotein lipids in healthy subjects with special reference to the linoleic acid pathway. 1985 Clin. Sci. pmid:3919990
Erskine KJ et al. An altered ratio of 18:2 (9,11) to 18:2 (9,12) linoleic acid in plasma phospholipids as a possible predictor of pre-eclampsia. 1985 Lancet pmid:2857904
Clarke SD and Salati LM Fatty acid-mediated disaggregation of acetyl-CoA carboxylase in isolated liver cells. 1985 Fed. Proc. pmid:2859222
Fink R et al. Increased free-radical activity in alcoholics. 1985 Lancet pmid:2862465
Banerjee N and Rosenthal MD High-affinity incorporation of 20-carbon polyunsaturated fatty acids by human skin fibroblasts. 1985 Biochim. Biophys. Acta pmid:2990563
Burton AF and Anderson FH Increased cholesteryl ester content in liver of mice fed lipid emulsion diets high in polyunsaturated fats. 1985 Jul-Aug JPEN J Parenter Enteral Nutr pmid:3839859
Andersen GE et al. Fatty acid changes in plasma lipids and lymphocyte phospholipids after infusion of intralipid to newborn infants. 1985 Nov-Dec JPEN J Parenter Enteral Nutr pmid:3934403
Gotoh K et al. Effects of unsaturated fatty acids on the peroxisomal enzyme activities of Tetrahymena pyriformis. 1986 J. Biochem. pmid:2880840
Nanji AA and Narod S Multiple sclerosis, latitude and dietary fat: is pork the missing link? 1986 Med. Hypotheses pmid:3638477
Kelly RA et al. Identification of NaK-ATPase inhibitors in human plasma as nonesterified fatty acids and lysophospholipids. 1986 J. Biol. Chem. pmid:3017943
Galland L Increased requirements for essential fatty acids in atopic individuals: a review with clinical descriptions. 1986 J Am Coll Nutr pmid:2424959
Narce M et al. [Chronologic studies of the effects of a hypoproteinic diet followed by an equilibrated diet on delta-6 and delta-5 desaturations of linoleic acid in liver microsomes in the rat]. 1986 Arch. Int. Physiol. Biochim. pmid:2430531
Iizuka Y and Murphy MJ Colony formation of granulocyte (CFU-g) and macrophage (CFU-m) precursors in serum- and albumin-free culture: effect of transferrin on clonal growth. 1986 Exp. Cell Biol. pmid:2433167
Kääpä P et al. Dietary fatty acids and platelet thromboxane production in puerperal women and their offspring. 1986 Am. J. Obstet. Gynecol. pmid:3089014
Youyou A et al. Recovery of altered fatty acid composition induced by a diet devoid of n-3 fatty acids in myelin, synaptosomes, mitochondria, and microsomes of developing rat brain. 1986 J. Neurochem. pmid:3940283
Maddaiah VT and Clejan S Growth hormone and liver mitochondria: time course of effects on respiration and fatty acid composition in hypophysectomized rats. 1986 Endocrinology pmid:2941269
Madison KC et al. Lipid composition of cultured murine keratinocytes. 1986 J. Invest. Dermatol. pmid:3090156
Kort WJ et al. Influence of the linoleic acid content of the diet on tumor growth in transplantable rat tumor models. 1986 Ann. Nutr. Metab. pmid:3963748
Ishiura S et al. Reticulocyte lipoxygenase, ingensin, and ATP-dependent proteolysis. 1986 FEBS Lett. pmid:3086125
Beneytout JL et al. Effect of isoquinoline alkaloids on soybean lipoxygenase activity in vitro. 1986 Prostaglandins pmid:3086939
Coene MC et al. Inhibition of rabbit platelet activation by lipoxygenase products of arachidonic and linoleic acid. 1986 Thromb. Res. pmid:3087009
Riemersma RA et al. Linoleic acid content in adipose tissue and coronary heart disease. 1986 Br Med J (Clin Res Ed) pmid:3087455
Rapoport S et al. Hydroperoxyfatty acids inactivate the reticulocyte lipoxygenase independently of a hydroperoxidase reaction. 1986 FEBS Lett. pmid:3087777
Okuno M et al. Serum fatty acid concentrations in patients on postoperative parenteral nutrition with and without fat. 1986 Jpn J Surg pmid:3088309
Heagerty AM et al. Influence of dietary linoleic acid on leucocyte sodium transport and blood pressure. 1986 Br Med J (Clin Res Ed) pmid:3089491
Wander RC and Berdanier CD Effects of type of dietary fat and carbohydrate on gluconeogenesis in isolated hepatocytes from BHE rats. 1986 J. Nutr. pmid:3091787
Ng LL and Hockaday TD Influence of dietary linoleic acid on leucocyte sodium transport and blood pressure. 1986 Br Med J (Clin Res Ed) pmid:3092960
Hansen HS et al. Apparent in vivo retroconversion of dietary arachidonic to linoleic acid in essential fatty acid-deficient rats. 1986 Biochim. Biophys. Acta pmid:3092868
Chambaz J et al. Essential fatty acid uptake and esterification in primary culture of rat hepatocytes. 1986 Biochim. Biophys. Acta pmid:3092869
Jensen GE and Clausen J Glutathione peroxidase activity, associated enzymes and substrates in blood cells from patients with multiple sclerosis--effects of antioxidant supplementation. 1986 Acta Pharmacol Toxicol (Copenh) pmid:3776606
Kapoulas VM and Andrikopoulos NK Detection of olive oil adulteration with linoleic acid-rich oils by reversed-phase high-performance liquid chromatography. 1986 J. Chromatogr. pmid:3782323
Jones DB et al. Indirect evidence of impairment of platelet desaturase enzymes in diabetes mellitus. 1986 Horm. Metab. Res. pmid:3013745
Hennig B et al. Linoleic acid hydroperoxide increases the transfer of albumin across cultured endothelial monolayers. 1986 Arch. Biochem. Biophys. pmid:3729421
Marshall MW et al. Effects of low fat diets varying in P/S ratio on nutrient intakes, fecal excretion, blood chemistry profiles, and fatty acids of adult men. 1986 J Am Coll Nutr pmid:3734273
Parsons HG et al. Modulation of human erythrocyte shape and fatty acids by diet. 1986 Biochim. Biophys. Acta pmid:3741859
Roguet R et al. In vivo distribution of linoleic acid in hairless rat skin following topical administration. 1986 Arch. Dermatol. Res. pmid:3789807
Caponnetto A et al. [Polyunsaturated fatty acids (omega-6) in tissues: variations induced by supplementation with linoleic acid and alloxan]. 1986 Boll. Soc. Ital. Biol. Sper. pmid:3790314
Nassar BA et al. The influence of dietary manipulation with n-3 and n-6 fatty acids on liver and plasma phospholipid fatty acids in rats. 1986 Lipids pmid:3796229
de Gomez Dumm IN et al. Effect of malonyl-CoA on delta 6 desaturation activity of rat liver microsomes. 1986 Lipids pmid:3796237
Effect of age on the linoleate content of skin acylglucosylceramide in mice. 1986 Nutr. Rev. pmid:3796906
Utermohlen V and Tucker MA Possible effects of dietary n-6 series polyunsaturated fatty acids on the development of immune dysfunction and infection. 1986 Proc Nutr Soc pmid:3797410
Holman RT Nutritional and biochemical evidences of acyl interaction with respect to essential polyunsaturated fatty acids. 1986 Prog. Lipid Res. pmid:3423089
Hansen HS and Jensen B Urinary excretion of arginine-vasopressin and prostaglandin E2 in essential fatty acid-deficient rats after oral supplementation with unsaturated fatty acid esters. 1986 J. Nutr. pmid:3080561
Okabe H et al. Effects of anti-convulsants on fatty acid metabolism in human serum. 1986 Tohoku J. Exp. Med. pmid:3705068
Leikin AI and Brenner RR Regulation of linoleic acid delta 6-desaturation by a cytosolic lipoprotein-like fraction in isolated rat liver microsomes. 1986 Biochim. Biophys. Acta pmid:2869785
Wolfram G et al. Pain, prostaglandins, and food lipids. Influences of dietary polyunsaturated fatty acids on eicosanoid synthesis and effects. 1986 Bibl Nutr Dieta pmid:2870709
Nijssen JG and van den Bosch H Coenzyme A-mediated transacylation of sn-2 fatty acids from phosphatidylcholine in rat lung microsomes. 1986 Biochim. Biophys. Acta pmid:3081034
Lee SH and Clandinin MT Effect of dietary fat on the utilization of fatty acids by myocardial tissue in the rat. 1986 J. Nutr. pmid:3794820
Szebeni J et al. Plasma fatty acid pattern including diene-conjugated linoleic acid in ethanol users and patients with ethanol-related liver disease. 1986 Alcohol. Clin. Exp. Res. pmid:3101533
Andre JC and Funk MO Determination of stereochemistry in the fatty acid hydroperoxide products of lipoxygenase catalysis. 1986 Anal. Biochem. pmid:3101541
Heleniak EP and Lamola SW A new prostaglandin disturbance syndrome in schizophrenia: delta-6-pyroluria. 1986 Med. Hypotheses pmid:3520252
Kovár J and Franĕk F Serum-free medium for hybridoma and parental myeloma cell cultivation. 1986 Meth. Enzymol. pmid:3523123
Guesry PR et al. Nutritional advantages of constituents of infant formulae formerly called "humanised". 1986 Reprod Nutr Dev pmid:3523658
Abeywardena MY et al. Effects of variable linoleate intake on aortic PGI2-like activity and fatty acid composition: difference between rat and marmoset (Callithrix jacchus). 1986 Prostaglandins Leukot Med pmid:3103139
Hawkey CJ et al. Strategies for preventing aspirin-induced gastric bleeding. 1986 Scand. J. Gastroenterol. Suppl. pmid:3103204
Anderson RJ et al. Peroxidised linoleic acid and experimental pancreatitis. 1986 Int. J. Pancreatol. pmid:3681026
Ishiura S et al. Effects of linoleic acid and cations on the activity of a novel high-molecular weight protease, ingensin, from human placenta. 1986 Int. J. Biochem. pmid:3530832
Izumi Y et al. Effects of dietary linoleic acid on blood pressure and renal function in subtotally nephrectomized rats. 1986 Proc. Soc. Exp. Biol. Med. pmid:3532127
Hoffmann P et al. Cardiovascular actions of dihydralazine as modified by dietary linoleic acid. 1986 Biomed. Biochim. Acta pmid:3535786
Siegel I et al. Inhibition of sperm motility and agglutination of sperm cells by free fatty acids in whole semen. 1986 Fertil. Steril. pmid:2868925
Tabachnick M and Korcek L Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. 1986 Biochim. Biophys. Acta pmid:2869786
Stewart ME et al. Dilutional effect of increased sebaceous gland activity on the proportion of linoleic acid in sebaceous wax esters and in epidermal acylceramides. 1986 J. Invest. Dermatol. pmid:2946783