Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Malaria, Cerebral D016779 1 associated lipids
Liposarcoma D008080 1 associated lipids
Gastroschisis D020139 1 associated lipids
Hypokinesia D018476 2 associated lipids
Darier Disease D007644 2 associated lipids
Aneurysm D000783 2 associated lipids
Circoviridae Infections D018173 2 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Lymphopenia D008231 2 associated lipids
Leptospirosis D007922 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Hong CY et al. Effect of pravastatin on fatty acid profile of low density lipoprotein in patients with hypercholesterolemia. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8446653
Claassen N et al. The effect of different n-6/n-3 essential fatty acid ratios on calcium balance and bone in rats. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:7675819
Prisco D et al. Platelet activation and platelet lipid composition in pulmonary cancer. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:7675825
Zhang J et al. Characteristics of fatty acid distribution is associated with colorectal cancer prognosis. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23465412
Tu WC et al. Omega-3 long chain fatty acid synthesis is regulated more by substrate levels than gene expression. 2010 Prostaglandins Leukot. Essent. Fatty Acids pmid:20573490
Bellini MJ et al. Effect of simvastatin on the uptake and metabolic conversion of palmitic, dihomo-gamma-linoleic and alpha-linolenic acids in A549 cells. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:14580370
Al-Turkmani MR et al. Fatty acid alterations and n-3 fatty acid supplementation in cystic fibrosis. 2007 Nov-Dec Prostaglandins Leukot. Essent. Fatty Acids pmid:18036797
Marín MC et al. Dietary long-chain fatty acids and visual response in malnourished nursing infants. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11133176
Hsi LC et al. Evaluation of the activity and localization of 15-lipoxygenase-1 after introduction into human colorectal carcinoma Caco-2 cells. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418015
Okita M et al. Effect of arachidonic acid-rich oil on lipids and arachidonate metabolites in ethanol- treated rats. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418023
Abeywardena MY et al. Dietary n-3 and n-6 polyunsaturated oils and airway contractility. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418024
Gueck T et al. Effects of essential fatty acids on mediators of mast cells in culture. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12711248
Louw L et al. Comparison of the fatty acid compositions in intraepithelial and infiltrating lesions of the cervix: part I, total fatty acid profiles. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9849650
Nixon JB et al. Evaluation of eicosanoids and NSAIDs as PPARgamma ligands in colorectal carcinoma cells. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12711249
Pasqualini ME et al. Association between E-cadherin expression by human colon, bladder and breast cancer cells and the 13-HODE:15-HETE ratio. A possible role of their metastatic potential. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12538085
Harris WS Linoleic acid and coronary heart disease. 2008 Sep-Nov Prostaglandins Leukot. Essent. Fatty Acids pmid:18951772
Soto-Guzman A et al. Role of arachidonic acid metabolism in Stat5 activation induced by oleic acid in MDA-MB-231 breast cancer cells. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23332799
Wenger FA et al. Does alpha-linolenic acid in combination with linoleic acid influence liver metastasis and hepatic lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters? 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10913224
Brenna T Tissue-specific LCPUFA accretion in fetal humans. 2012 Jan-Feb Prostaglandins Leukot. Essent. Fatty Acids pmid:22078006
Kim RS and Zaborniak CL The aldehydic metabolites of linoleic acid are cytotoxic against human breast cancer cells. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1946549
Mouradian M et al. Key roles for GRB2-associated-binding protein 1, phosphatidylinositol-3-kinase, cyclooxygenase 2, prostaglandin E2 and transforming growth factor alpha in linoleic acid-induced upregulation of lung and breast cancer cell growth. 2014 Prostaglandins Leukot. Essent. Fatty Acids pmid:24374147
elAttar TM et al. Comparison of the inhibitory effect of polyunsaturated fatty acids on prostaglandin synthesis. II. Fibroblasts. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:1971442
Hendrich S et al. Phenobarbital increases rat hepatic prostaglandin F2 alpha, glutathione S-transferase activity and oxidative stress. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:2011611
Gibson R and Makrides M α-Linolenate reduces the dietary requirement for linoleate in the growing rat. 2011 Prostaglandins Leukot. Essent. Fatty Acids pmid:22019216
Das I and Khan NS Increased arachidonic acid induced platelet chemiluminescence indicates cyclooxygenase overactivity in schizophrenic subjects. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9610837
Kikuchi S et al. Modulation of eosinophil chemotactic activities to leukotriene B4 by n-3 polyunsaturated fatty acids. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9610849
Strandvik B et al. Prostanoid biosynthesis in patients with cystic fibrosis. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:9014220
Guesnet P et al. α-Linolenate reduces the dietary requirement for linoleate in the growing rat. 2011 Prostaglandins Leukot. Essent. Fatty Acids pmid:21880475
Strandvik B Fatty acid metabolism in cystic fibrosis. 2010 Prostaglandins Leukot. Essent. Fatty Acids pmid:20673710
Tonogai Y and Tai HH Quantitation of 13-hydroxyoctadecadienoic acid (13-HODE) by radioimmunoassay. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:2111553
Matsuba S et al. Effect of dietary linoleate/alpha-linolenate balance on experimentally induced gastric injury in rats. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9888206
Shapiro H et al. Beyond the classic eicosanoids: Peripherally-acting oxygenated metabolites of polyunsaturated fatty acids mediate pain associated with tissue injury and inflammation. 2016 Prostaglandins Leukot. Essent. Fatty Acids pmid:27067460
Risé P et al. Different patterns characterize Omega 6 and Omega 3 long chain polyunsaturated fatty acid levels in blood from Italian infants, children, adults and elderly. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23910046
Kuipers RS et al. Gestational age dependent changes of the fetal brain, liver and adipose tissue fatty acid compositions in a population with high fish intakes. 2012 Prostaglandins Leukot. Essent. Fatty Acids pmid:22425685
Hover CG and Kulkarni AP A simple and efficient method for hemoglobin removal from mammalian tissue cytosol by zinc sulfate and its application to the study of lipoxygenase. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780874
Charnock JS Gamma-linolenic acid provides additional protection against ventricular fibrillation in aged rats fed linoleic acid rich diets. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780878
Sakuma S et al. The effects of fatty acyl CoA esters on the formation of prostaglandin and arachidonoyl-CoA formed from arachidonic acid in rabbit kidney medulla microsomes. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11161586
Mayer M Linoleic-acid-dependent slowing of erythrocyte sedimentation in multiple sclerosis. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1815242
Gibson RA et al. Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:22515943
Krumhardt B and Dupont J The relationship between thromboxane and cytosolic calcium modifiers in rat platelets. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1652770
Perkins DM and Duncan JR The effect of gamma-linolenic acid and zinc supplementation on the growth of normal and tumour cells in vitro. 1991 Prostaglandins Leukot. Essent. Fatty Acids pmid:1881941
Porras-Reyes BH et al. Essential fatty acids are not required for wound healing. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1603819
Punchard NA et al. Analysis of the intestinal absorption of essential fatty acids in vivo in the rat. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10765976
Kuipers RS et al. Milk in the island of Chole [Tanzania] is high in lauric, myristic, arachidonic and docosahexaenoic acids, and low in linoleic acid reconstructed diet of infants born to our ancestors living in tropical coastal regions. 2007 Prostaglandins Leukot. Essent. Fatty Acids pmid:17383169
Tisdale MJ Mechanism of lipid mobilization associated with cancer cachexia: interaction between the polyunsaturated fatty acid, eicosapentaenoic acid, and inhibitory guanine nucleotide-regulatory protein. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:8380931
Glew RH et al. Fatty acid composition of the milk lipids of Nepalese women: correlation between fatty acid composition of serum phospholipids and melting point. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728165
Derian CK and Lewis DF Activation of 15-lipoxygenase by low density lipoprotein in vascular endothelial cells. Relationship to the oxidative modification of low density lipoprotein. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1546066
Gregor JI et al. Does enteral nutrition of dietary polyunsaturated fatty acids promote oxidative stress and tumour growth in ductal pancreatic cancer? Experimental trial in Syrian Hamster. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:16226437
Novak EM et al. Low linoleic acid may facilitate Δ6 desaturase activity and docosahexaenoic acid accretion in human fetal development. 2012 Prostaglandins Leukot. Essent. Fatty Acids pmid:22365109
Turpeinen AM et al. A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9844997