| MeSH term | MeSH ID | Detail |
|---|---|---|
| Olfaction Disorders | D000857 | 17 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Aortic Diseases | D001018 | 11 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Arteriosclerosis Obliterans | D001162 | 8 associated lipids |
| Ascites | D001201 | 25 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Biliary Atresia | D001656 | 4 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- J. Lipid Res. (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kang J et al. | Identification of three genes encoding microsomal oleate desaturases (FAD2) from the oilseed crop Camelina sativa. | 2011 | Plant Physiol. Biochem. | pmid:21215650 |
| Andreu I et al. | Probing lipid peroxidation by using linoleic acid and benzophenone. | 2011 | Chemistry | pmid:21793062 |
| Shibata H et al. | Effect of supplementation of soy sauce oil and Ca salts of fatty acids on rumen fermentation, milk production and conjugated linoleic acid in milk of dairy cows. | 2011 | Anim. Sci. J. | pmid:21794014 |
| Prasad A and PospÃÅ¡il P | Linoleic acid-induced ultra-weak photon emission from Chlamydomonas reinhardtii as a tool for monitoring of lipid peroxidation in the cell membranes. | 2011 | PLoS ONE | pmid:21799835 |
| Li YC et al. | Effects of conjugated linoleic acid on cleavage of amyloid precursor protein via PPARγ. | 2011 | Neurol. Sci. | pmid:21800078 |
| Shchepinov MS et al. | Isotopic reinforcement of essential polyunsaturated fatty acids diminishes nigrostriatal degeneration in a mouse model of Parkinson's disease. | 2011 | Toxicol. Lett. | pmid:21906664 |
| Aktumsek A et al. | Screening for in vitro antioxidant properties and fatty acid profiles of five Centaurea L. species from Turkey flora. | 2011 | Food Chem. Toxicol. | pmid:21878362 |
| Guesnet P et al. | α-Linolenate reduces the dietary requirement for linoleate in the growing rat. | 2011 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21880475 |
| Vinaixa M et al. | Metabolomics reveals reduction of metabolic oxidation in women with polycystic ovary syndrome after pioglitazone-flutamide-metformin polytherapy. | 2011 | PLoS ONE | pmid:22194988 |
| Narwaley M et al. | Drug-induced protein free radical formation is attenuated by unsaturated fatty acids by scavenging drug-derived phenyl radical metabolites. | 2011 | Chem. Res. Toxicol. | pmid:21671642 |
| Göçer H and Gülçin I | Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties. | 2011 | Int J Food Sci Nutr | pmid:21631390 |
| Lautenslager GT et al. | Effects of nonenzymatic glycation and fatty acids on functional properties of human albumin. | 2011 | Metab. Clin. Exp. | pmid:21632076 |
| Li M et al. | Isolation of a novel C18-Δ9 polyunsaturated fatty acid specific elongase gene from DHA-producing Isochrysis galbana H29 and its use for the reconstitution of the alternative Δ8 pathway in Saccharomyces cerevisiae. | 2011 | Biotechnol. Lett. | pmid:21538137 |
| Ueda Y et al. | Effect of dietary lipids on longevity and memory in the SAMP8 mice. | 2011 | J. Nutr. Sci. Vitaminol. | pmid:21512289 |
| Pi F et al. | Solid-state low temperature→middle temperature phase transition of linoleic acid studied by FTIR spectroscopy. | 2011 | J Phys Chem B | pmid:21520953 |
| Wong WT et al. | Relative contribution of individual oxidized components in ox-LDL to inhibition on endothelium-dependent relaxation in rat aorta. | 2011 | Nutr Metab Cardiovasc Dis | pmid:20005687 |
| Tuo Y et al. | Long-term exposure of INS-1 rat insulinoma cells to linoleic acid and glucose in vitro affects cell viability and function through mitochondrial-mediated pathways. | 2011 | Endocrine | pmid:21161439 |
| Hamberg M | Stereochemistry of hydrogen removal during oxygenation of linoleic acid by singlet oxygen and synthesis of 11(S)-deuterium-labeled linoleic acid. | 2011 | Lipids | pmid:21161604 |
| Lam YY et al. | Insulin-stimulated glucose uptake and pathways regulating energy metabolism in skeletal muscle cells: the effects of subcutaneous and visceral fat, and long-chain saturated, n-3 and n-6 polyunsaturated fatty acids. | 2011 Jul-Aug | Biochim. Biophys. Acta | pmid:21570480 |
| de Luis DA et al. | Double blind randomized clinical trial controlled by placebo with an alpha linoleic acid and prebiotic enriched cookie on risk cardiovascular factor in obese patients. | 2011 Jul-Aug | Nutr Hosp | pmid:22470031 |
| Aluf Y et al. | Alterations in striatal oxidative stress level produced by pharmacological manipulation of dopamine as shown by a novel synthetic marker molecule. | 2011 Jul-Aug | Neuropharmacology | pmid:21414328 |
| Permiakova MD and Trufanov VA | [Effect of soybean lipoxygenae on baking properties of wheat flour]. | 2011 May-Jun | Prikl. Biokhim. Mikrobiol. | pmid:21790037 |
| Qu WX et al. | Analysis of fatty acids in A. szechenyianum Gay. by microwave-assisted extraction and gas chromatography-mass spectrometry. | 2011 May-Jun | Phytochem Anal | pmid:20848395 |
| Ramandi NF et al. | Central composite design for the optimization of supercritical carbon dioxide fluid extraction of fatty acids from Borago officinalis L. flower. | 2011 Nov-Dec | J. Food Sci. | pmid:22416687 |
| Olszewska MA | Variation in the phenolic content and in vitro antioxidant activity of Sorbus aucuparia leaf extracts during vegetation. | 2011 Nov-Dec | Acta Pol Pharm | pmid:22125960 |
| Olszewska MA | In vitro antioxidant activity and total phenolic content of the inflorescences, leaves and fruits of Sorbus torminalis (L.) Crantz. | 2011 Nov-Dec | Acta Pol Pharm | pmid:22125961 |
| Kezutyte T et al. | Study of tolnaftate release from fatty acids containing ointment and penetration into human skin ex vivo. | 2011 Nov-Dec | Acta Pol Pharm | pmid:22125963 |
| China R et al. | In vitro antioxidant activity of different cultivars of banana flower (Musa paradicicus L.) extracts available in India. | 2011 Nov-Dec | J. Food Sci. | pmid:22416691 |
| Lasa A et al. | The combination of resveratrol and CLA does not increase the delipidating effect of each molecule in 3T3-L1 adipocytes. | 2011 Sep-Oct | Nutr Hosp | pmid:22072344 |
| Okui T et al. | Cis-9,trans-11-conjugated linoleic acid promotes neuronal differentiation through regulation of Hes6 mRNA and cell cycle in cultured neural stem cells. | 2011 Sep-Oct | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21723718 |
| Mujtaba SF et al. | Production of ROS by photosensitized anthracene under sunlight and UV-R at ambient environmental intensities. | 2011 Sep-Oct | Photochem. Photobiol. | pmid:21668866 |
| Sabir A et al. | The fatty acid and tocopherol constituents of the seed oil extracted from 21 grape varieties (Vitis spp.). | 2012 | J. Sci. Food Agric. | pmid:22271548 |
| Ties P and Barringer S | Influence of lipid content and lipoxygenase on flavor volatiles in the tomato peel and flesh. | 2012 | J. Food Sci. | pmid:22757705 |
| Salleh WM et al. | Chemical compositions, antioxidant and antimicrobial activity of the essential oils of Piper officinarum (Piperaceae). | 2012 | Nat Prod Commun | pmid:23413576 |
| Bonacci G et al. | Conjugated linoleic acid is a preferential substrate for fatty acid nitration. | 2012 | J. Biol. Chem. | pmid:23144452 |
| Gutla PV et al. | Modulation of plant TPC channels by polyunsaturated fatty acids. | 2012 | J. Exp. Bot. | pmid:23105130 |
| Moodley R et al. | Elemental composition and fatty acid profile of the edible fruits of Amatungula (Carissa macrocarpa) and impact of soil quality on chemical characteristics. | 2012 | Anal. Chim. Acta | pmid:22632042 |
| Ruparel S et al. | Plasticity of cytochrome P450 isozyme expression in rat trigeminal ganglia neurons during inflammation. | 2012 | Pain | pmid:22633978 |
| Jarret RL and Levy IJ | Oil and fatty acid contents in seed of Citrullus lanatus Schrad. | 2012 | J. Agric. Food Chem. | pmid:22540530 |
| Dramane G et al. | STIM1 regulates calcium signaling in taste bud cells and preference for fat in mice. | 2012 | J. Clin. Invest. | pmid:22546859 |
| Macaluso F et al. | Effect of conjugated linoleic acid on testosterone levels in vitro and in vivo after an acute bout of resistance exercise. | 2012 | J Strength Cond Res | pmid:22614148 |
| Naqvi AZ et al. | Dietary fatty acids and peripheral artery disease in adults. | 2012 | Atherosclerosis | pmid:22552117 |
| Banti CN et al. | Mixed ligand-silver(I) complexes with anti-inflammatory agents which can bind to lipoxygenase and calf-thymus DNA, modulating their function and inducing apoptosis. | 2012 | Metallomics | pmid:22552402 |
| Dubé E et al. | Modulation of fatty acid transport and metabolism by maternal obesity in the human full-term placenta. | 2012 | Biol. Reprod. | pmid:22553224 |
| Cortie CH and Else PL | Dietary docosahexaenoic Acid (22:6) incorporates into cardiolipin at the expense of linoleic Acid (18:2): analysis and potential implications. | 2012 | Int J Mol Sci | pmid:23203135 |
| Coimbra MC and Jorge N | Fatty acids and bioactive compounds of the pulps and kernels of Brazilian palm species, guariroba (Syagrus oleraces), jerivá (Syagrus romanzoffiana) and macaúba (Acrocomia aculeata). | 2012 | J. Sci. Food Agric. | pmid:21922463 |
| Marincola FC et al. | A metabolomic study of preterm human and formula milk by high resolution NMR and GC/MS analysis: preliminary results. | 2012 | J. Matern. Fetal. Neonatal. Med. | pmid:23025771 |
| Ruparel S et al. | The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain. | 2012 | Mol Pain | pmid:23006841 |
| Martorell P et al. | Caenorhabditis elegans as a model to study the effectiveness and metabolic targets of dietary supplements used for obesity treatment: the specific case of a conjugated linoleic acid mixture (Tonalin). | 2012 | J. Agric. Food Chem. | pmid:23072574 |
| Hu ZP et al. | Metabonomic profiling of TASTPM transgenic Alzheimer's disease mouse model. | 2012 | J. Proteome Res. | pmid:23078235 |
| Heinze VM and Actis AB | Dietary conjugated linoleic acid and long-chain n-3 fatty acids in mammary and prostate cancer protection: a review. | 2012 | Int J Food Sci Nutr | pmid:21762028 |
| Trevizan L et al. | Maintenance of arachidonic acid and evidence of Δ5 desaturation in cats fed γ-linolenic and linoleic acid enriched diets. | 2012 | Lipids | pmid:22249937 |
| Georgiadi A et al. | Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart. | 2012 | Physiol. Genomics | pmid:22274564 |
| Alvheim AR et al. | Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity. | 2012 | Obesity (Silver Spring) | pmid:22334255 |
| Weiss LA et al. | The omega-6 fatty acid linoleic acid is associated with risk of gastroschisis: a novel dietary risk factor. | 2012 | Am. J. Med. Genet. A | pmid:22315197 |
| Sun X et al. | Lipid peroxidation and DNA adduct formation in lymphocytes of premenopausal women: Role of estrogen metabolites and fatty acid intake. | 2012 | Int. J. Cancer | pmid:22322480 |
| Zhu X et al. | Release property and antioxidant effectiveness of tocopherol-incorporated LDPE/PP blend films. | 2012 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:22257167 |
| Tanaka R et al. | Prenylated acylphloroglucinol derivatives: isoprenomics-based design, syntheses and antioxidative activities. | 2012 | Adv. Exp. Med. Biol. | pmid:22259110 |
| Raatz SK et al. | Total dietary fat and fatty acid content modifies plasma phospholipid fatty acids, desaturase activity indices, and urinary prostaglandin E in women. | 2012 | Nutr Res | pmid:22260857 |
| Gu L et al. | Chemical and cellular antioxidant activity of two novel peptides designed based on glutathione structure. | 2012 | Food Chem. Toxicol. | pmid:22940538 |
| Sandoval-Montemayor NE et al. | Chemical composition of hexane extract of Citrus aurantifolia and anti-Mycobacterium tuberculosis activity of some of its constituents. | 2012 | Molecules | pmid:22992784 |
| Rodrigues HG et al. | Oral administration of oleic or linoleic acid accelerates the inflammatory phase of wound healing. | 2012 | J. Invest. Dermatol. | pmid:21881592 |
| de Batlle J et al. | Association between Ω3 and Ω6 fatty acid intakes and serum inflammatory markers in COPD. | 2012 | J. Nutr. Biochem. | pmid:21889886 |
| Koch C et al. | Linoleic acid positioning in psi factor producing oxygenase A, a fusion protein with an atypical cytochrome P450 activity. | 2012 | FEBS J. | pmid:21920024 |
| Ezebuo FC et al. | Effects of sodium dodecyl sulphate on enhancement of lipoxygenase activity of hemoglobin. | 2012 | Indian J. Exp. Biol. | pmid:23986967 |
| Burstein S et al. | N-Amino acid linoleoyl conjugates: anti-inflammatory activities. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22217875 |
| Cheguru P et al. | Adipocyte differentiation-specific gene transcriptional response to C18 unsaturated fatty acids plus insulin. | 2012 | Pflugers Arch. | pmid:22218833 |
| Mormile R et al. | Linoleic acid and colorectal cancer cell growth suppression: is the deregulation of mitochondrial survivin the key factor? | 2012 | Int J Colorectal Dis | pmid:22231621 |
| Luévano-MartÃnez LA et al. | A critical tyrosine residue determines the uncoupling protein-like activity of the yeast mitochondrial oxaloacetate carrier. | 2012 | Biochem. J. | pmid:22236206 |
| Jorge AT et al. | Schinus terebinthifolius Raddi extract and linoleic acid from Passiflora edulis synergistically decrease melanin synthesis in B16 cells and reconstituted epidermis. | 2012 | Int J Cosmet Sci | pmid:22738140 |
| Manzoor M et al. | Variation in minerals, phenolics and antioxidant activity of peel and pulp of different varieties of peach (Prunus persica L.) fruit from Pakistan. | 2012 | Molecules | pmid:22728349 |
| Tao XM et al. | Enhanced anticancer activity of gemcitabine coupling with conjugated linoleic acid against human breast cancer in vitro and in vivo. | 2012 | Eur J Pharm Biopharm | pmid:22728546 |
| Zhou YJ et al. | Linoleic acid activates GPR40/FFA1 and phospholipase C to increase [Ca2+]i release and insulin secretion in islet beta-cells. | 2012 | Chin. Med. Sci. J. | pmid:22734209 |
| Dundar A et al. | Antioxidant properties, chemical composition and nutritional value of Terfezia boudieri (Chatin) from Turkey. | 2012 | Food Sci Technol Int | pmid:22773542 |
| Shen J et al. | Effect of essential fatty acids on glucose-induced cytotoxicity to retinal vascular endothelial cells. | 2012 | Lipids Health Dis | pmid:22781401 |
| Al-Said MS et al. | Edible oils for liver protection: hepatoprotective potentiality of Moringa oleifera seed oil against chemical-induced hepatitis in rats. | 2012 | J. Food Sci. | pmid:22757719 |
| Gören AC et al. | Fatty acid composition and chemotaxonomic evaluation of species of Stachys. | 2012 | Nat. Prod. Res. | pmid:21859257 |
| Takahashi T et al. | Effect of linoleic acid albumin in a dilution solution and long-term equilibration for freezing of bovine spermatozoa with poor freezability. | 2012 | Reprod. Domest. Anim. | pmid:21635578 |
| Kowalska A et al. | Impact of diets with different proportions of linseed and sunflower oils on the growth, liver histology, immunological and chemical blood parameters, and proximate composition of pikeperch Sander lucioperca (L.). | 2012 | Fish Physiol. Biochem. | pmid:21656178 |
| Maqbool A et al. | Relation between dietary fat intake type and serum fatty acid status in children with cystic fibrosis. | 2012 | J. Pediatr. Gastroenterol. Nutr. | pmid:22699835 |
| Li D et al. | Antitumor efficacy of a novel CLA-PTX microemulsion against brain tumors: in vitro and in vivo findings. | 2012 | Int J Nanomedicine | pmid:23269869 |
| Romano R et al. | Comparison of the frying performance of olive oil and palm superolein. | 2012 | J. Food Sci. | pmid:22490166 |
| Manosroi A et al. | Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction. | 2012 | Eur J Pharm Biopharm | pmid:22490981 |
| Smink W et al. | Linoleic and α-linolenic acid as precursor and inhibitor for the synthesis of long-chain polyunsaturated fatty acids in liver and brain of growing pigs. | 2012 | Animal | pmid:22436184 |
| Zened A et al. | In vitro study of dietary factors affecting the biohydrogenation shift from trans-11 to trans-10 fatty acids in the rumen of dairy cows. | 2012 | Animal | pmid:22436225 |
| Eserian JK et al. | Effects of polyunsaturated fatty acids on cocaine-conditioned place preference in mice. | 2012 | Nutr Neurosci | pmid:22390908 |
| Fei J et al. | ω-6 lipids regulate PPAR turnover via reciprocal switch between PGC-1 alpha and ubiquitination. | 2012 | Atherosclerosis | pmid:22464285 |
| Marei WF et al. | Differential effects of linoleic and alpha-linolenic fatty acids on spatial and temporal mitochondrial distribution and activity in bovine oocytes. | 2012 | Reprod. Fertil. Dev. | pmid:22697118 |
| Jarvis MF | Cytochrome P450 mediated linoleic acid metabolism in peripheral inflammatory nociception. | 2012 | Pain | pmid:22681878 |
| Passos PP et al. | Dopaminergic cell populations of the rat substantia nigra are differentially affected by essential fatty acid dietary restriction over two generations. | 2012 | J. Chem. Neuroanat. | pmid:22687395 |
| Khan R et al. | Variation in oil content and fatty acid composition of the seed oil of Acacia species collected from the northwest zone of India. | 2012 | J. Sci. Food Agric. | pmid:22351513 |
| Chen MH and Nelson EB | Microbial-induced carbon competition in the spermosphere leads to pathogen and disease suppression in a municipal biosolids compost. | 2012 | Phytopathology | pmid:22352306 |
| Novak EM et al. | Low linoleic acid may facilitate Δ6 desaturase activity and docosahexaenoic acid accretion in human fetal development. | 2012 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22365109 |
| Xie J et al. | Composition of fatty oils from semen ziziphi spinosae and its cardiotonic effect on isolated toad hearts. | 2012 | Nat. Prod. Res. | pmid:21707231 |
| He M et al. | Effect of dietary fat blend enriched in oleic or linoleic acid and monensin supplementation on dairy cattle performance, milk fatty acid profiles, and milk fat depression. | 2012 | J. Dairy Sci. | pmid:22365227 |
| Castro LF et al. | Functional desaturase Fads1 (Δ5) and Fads2 (Δ6) orthologues evolved before the origin of jawed vertebrates. | 2012 | PLoS ONE | pmid:22384110 |
| Li KL et al. | Characterization of cumulus expansion-inhibiting factor (CEIF) in goat follicles. | 2012 | Biol. Reprod. | pmid:22402961 |
| Dall'Asta C et al. | Role of maize hybrids and their chemical composition in Fusarium infection and fumonisin production. | 2012 | J. Agric. Food Chem. | pmid:22409349 |
| Mulligan CM et al. | Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart. | 2012 | Cardiovasc. Res. | pmid:22411972 |
| Gull J et al. | Variation in antioxidant attributes at three ripening stages of guava (Psidium guajava L.) fruit from different geographical regions of Pakistan. | 2012 | Molecules | pmid:22418924 |