Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Berdeaux O et al. | In vitro desaturation or elongation of monotrans isomers of linoleic acid by rat liver microsomes. | 1998 | Mol. Cell. Biochem. | pmid:9746207 |
Kanazawa K and Ashida H | Catabolic fate of dietary trilinoleoylglycerol hydroperoxides in rat gastrointestines. | 1998 | Biochim. Biophys. Acta | pmid:9748647 |
Kanazawa K and Ashida H | Dietary hydroperoxides of linoleic acid decompose to aldehydes in stomach before being absorbed into the body. | 1998 | Biochim. Biophys. Acta | pmid:9748650 |
Ando H et al. | Linoleic acid and alpha-linolenic acid lightens ultraviolet-induced hyperpigmentation of the skin. | 1998 | Arch. Dermatol. Res. | pmid:9749992 |
Kuratko CN and Constante BJ | Linoleic acid and tumor necrosis factor-alpha increase manganese superoxide dismutase activity in intestinal cells. | 1998 | Cancer Lett. | pmid:9751273 |
Benito S et al. | Phospholipid fatty acid composition affects enzymatic antioxidant defenses in cultured Swiss 3T3 fibroblasts. | 1997 Oct-Dec | Redox Rep. | pmid:9754326 |
Spalinger JH et al. | Uptake and metabolism of structured triglyceride by Caco-2 cells: reversal of essential fatty acid deficiency. | 1998 | Am. J. Physiol. | pmid:9756493 |
Wijewickreme AN and Kitts DD | Modulation of metal-induced cytotoxicity by maillard reaction products isolated from coffee brew. | 1998 | J. Toxicol. Environ. Health Part A | pmid:9761134 |
Obukowicz MG et al. | Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9765335 |
Iwamoto S et al. | Effects of fatty acids on liver metastasis of ACL-15 rat colon cancer cells. | 1998 | Nutr Cancer | pmid:9770727 |