Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Dubnov G and Berry EM | Omega-6/omega-3 fatty acid ratio: the Israeli paradox. | 2003 | World Rev Nutr Diet | pmid:14579685 |
Zampelas A et al. | Linoleic acid to alpha-linolenic acid ratio. From clinical trials to inflammatory markers of coronary artery disease. | 2003 | World Rev Nutr Diet | pmid:14579686 |
Hamazaki T and Okuyama H | The Japan Society for Lipid Nutrition recommends to reduce the intake of linoleic acid. A review and critique of the scientific evidence. | 2003 | World Rev Nutr Diet | pmid:14579687 |
Okuyama H et al. | New Cholesterol Guidelines for Longevity (2010). | 2011 | World Rev Nutr Diet | pmid:21865826 |
Legrand P et al. | Update of French nutritional recommendations for fatty acids. | 2011 | World Rev Nutr Diet | pmid:21865827 |
Holman RT | Highpoints in an affair with polyunsaturated fatty acids. | 1991 | World Rev Nutr Diet | pmid:2053355 |
Sugano M | Isomeric fatty acids: their physiological significance and health implications. | 2001 | World Rev Nutr Diet | pmid:11935963 |
Zheng HF et al. | Effects of unsaturated fatty acids on calcium-activated potassium current in gastric myocytes of guinea pigs. | 2005 | World J. Gastroenterol. | pmid:15655819 |
Chen BQ et al. | Effects of c9,t11-conjugated linoleic acid on adhesion of human gastric carcinoma cell line SGC-7901. | 2004 | World J. Gastroenterol. | pmid:15133841 |
Chen BQ et al. | Inhibition of conjugated linoleic acid on mouse forestomach neoplasia induced by benzo (a) pyrene and chemopreventive mechanisms. | 2003 | World J. Gastroenterol. | pmid:12508349 |
Brouwer DA et al. | The dietary fatty acids of patients with coronary artery disease and controls in Curaçao. Implications for primary and secondary prevention. | 1997 | West Indian Med J | pmid:9260535 |
Xue Y et al. | [Effects of conjugated linoleic acid on the metastasis of mouse melanoma B16-MB]. | 2001 | Wei Sheng Yan Jiu | pmid:11255760 |
Lu WH et al. | [Screening and identification of a strain for hydroxylation of nicotinic acid]. | 2005 | Wei Sheng Wu Xue Bao | pmid:15847152 |
Moon C et al. | Modeling sulfate removal by inhibited mesophilic mixed anaerobic communities using a statistical approach. | 2013 | Water Res. | pmid:23466036 |
Markov KhM et al. | [Effect of dietary linoleic acid on the platelet aggregation, fatty acid composition of platelet phospholipids and synthesis of platelet prostaglandins in rats]. | 1988 Jul-Aug | Vopr. Med. Khim. | pmid:3195130 |
Bondarenko LB et al. | [Effect of 1,25-dihydroxyvitamin D3 on 15-lipoxygenase activity]. | 1995 May-Jun | Vopr. Med. Khim. | pmid:8585174 |
Markov KhM and Kucherenko AG | [Effect of diets with various contents of linoleic acid on the prostaglandin system in the rat kidney]. | 1988 Mar-Apr | Vopr. Med. Khim. | pmid:3400199 |
Buko VU et al. | [Changes in the fatty acid composition of erythrocyte membranes in patients with chronic alcoholism under the effect of a diet enriched with linoleic acid]. | 1989 Nov-Dec | Vopr Pitan | pmid:2629246 |
ONDREICHKA R et al. | [CHANGES IN THE CHEMICAL AND PHYSICAL PROPERTIES OF LARD AND BUTTER DURING HEATING]. | 1963 Nov-Dec | Vopr Pitan | pmid:14149605 |
Atrokhov VV and Markov KhM | [Influence of rations with various linoleic acid contents on the fatty acid composition of phospholipids in blood platelets of rats]. | 1987 Sep-Oct | Vopr Pitan | pmid:2894094 |