Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Singer P et al. | Attenuation of high blood pressure by primrose oil, linseed oil and sunflowerseed oil in spontaneously hypertensive rats. | 1984 | Biomed. Biochim. Acta | pmid:6097233 |
| Tarozzi G et al. | Fatty acid composition of single brain structures following different alpha linolenate dietary supplementations. | 1984 | Acta Vitaminol. Enzymol. | pmid:6098184 |
| Codde JP et al. | Dissociation of effects of dietary fatty acids on blood pressure and prostanoid metabolism in Goldblatt hypertensive rats. | 1984 | J. Hypertens. | pmid:6099384 |
| Chen TC et al. | Modulation of 1,25-dihydroxyvitamin D3 receptor by phospholipids and fatty acids. | 1984 | J. Lipid Res. | pmid:6099395 |
| Murphy MG | Increasing membrane polyunsaturated fatty-acid content augments cyclic AMP formation and prostaglandin production in NIE-115 neuroblastoma. | 1984 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:6099586 |
| Mirouze J et al. | [How is diabetic nutrition understood in 1984?]. | 1984 | Journ Annu Diabetol Hotel Dieu | pmid:6100378 |
| Frankel EN | Chemistry of free radical and singlet oxidation of lipids. | 1984 | Prog. Lipid Res. | pmid:6100997 |
| Volpe JJ and Obert KA | Coordinate regulation of cholesterol synthesis and 3-hydroxy-3-methylglutaryl coenzyme A synthase but not 3-hydroxy-3-methylglutaryl coenzyme A reductase in C-6 glia. | 1981 | Arch. Biochem. Biophys. | pmid:6118099 |
| Cheah AM | Effect of long chain unsaturated fatty acids on the calcium transport of sarcoplasmic reticulum. | 1981 | Biochim. Biophys. Acta | pmid:6118177 |
| Hoelgaard A and Møllgaard B | Permeation of linoleic acid through skin in vitro. | 1982 | J. Pharm. Pharmacol. | pmid:6127396 |
| Enser M and Roberts JL | The regulation of hepatic stearoyl-coenzyme A desaturase in obese-hyperglycaemic (ob/ob) mice by food intake and the fatty acid composition of the diet. | 1982 | Biochem. J. | pmid:6128973 |
| Gerzer R et al. | Calcium-induced release from platelet membranes of fatty acids that modulate soluble guanylate cyclase. | 1983 | J. Pharmacol. Exp. Ther. | pmid:6134818 |
| Wood DA et al. | Adipose tissue and platelet fatty acids and coronary heart disease in Scottish men. | 1984 | Lancet | pmid:6146032 |
| Asakawa T et al. | Ca2+-activated, fatty acid-dependent guanylate cyclase in synaptic plasma membranes and its requirement for Ca2+ and Mg-GTP in the activation. | 1984 | Adv. Exp. Med. Biol. | pmid:6149673 |
| Albrecht R et al. | [Induction by lindane of microsomal monoxygenases of the liver in the rat: effects of a 72-hour fast]. | 1981 | Food Cosmet Toxicol | pmid:6167500 |
| Goldmacher VS | Immobilization of protein molecules on liposomes. Anchorage by artificially bound unsaturated hydrocarbon tails. | 1983 | Biochem. Pharmacol. | pmid:6189496 |
| Van Alstine JM and Brooks DE | Cell membrane abnormality detected in erythrocytes from patients with multiple sclerosis by partition in two-polymer aqueous-phase systems. | 1984 | Clin. Chem. | pmid:6199135 |
| Mitranic MM et al. | The effect of linoleic acid and benzyl alcohol on the activity of glycosyltransferases of rat liver Golgi membranes and some soluble glycosyltransferases. | 1982 | Biochim. Biophys. Acta | pmid:6217837 |
| Hoover RL et al. | Role of cholesterol in the capping of surface immunoglobulin receptors on murine lymphocytes. | 1983 | J. Cell Biol. | pmid:6223042 |
| Sanders TA et al. | The influence of a maternal diet rich in linoleic acid on brain and retinal docosahexaenoic acid in the rat. | 1984 | Br. J. Nutr. | pmid:6228249 |
| Breton M et al. | Linoleate incorporation into rat liver membranes phospholipids: effect on plasma membrane ATPase activities and physical properties. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6230079 |
| Monnier LH et al. | Plasma lipid fatty acids and platelet function in insulin-dependent diabetic patients. | 1983 | Diabete Metab | pmid:6230269 |
| Benaim G et al. | Different conformational states of the purified Ca2+-ATPase of the erythrocyte plasma membrane revealed by controlled trypsin proteolysis. | 1984 | J. Biol. Chem. | pmid:6234313 |
| Narce M and Poisson JP | [In vitro study of delta 6- and delta 5-desaturations of linoleic and dihomo-gamma-linolenic acids during the development of arterial hypertension as a function of age in spontaneously hypertensive rats (SHR) as compared to normotensive rats (WKY)]. | 1984 | C. R. Seances Soc. Biol. Fil. | pmid:6241017 |
| Naegelen J et al. | [Placental fatty acids in the guinea pig during pregnancy]. | 1984 | C. R. Seances Soc. Biol. Fil. | pmid:6241019 |
| Vaddadi KS | The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. | 1981 | Prostaglandins Med | pmid:6269135 |
| Gavigan SJ and Knight BL | Catabolism of low-density lipoprotein by fibroblasts cultured in medium supplemented with saturated or unsaturated free fatty acids. | 1981 | Biochim. Biophys. Acta | pmid:6271233 |
| Bonacossa A et al. | Effect of corticosterone, hydrocortisone and prostaglandin fatty acid precursors on the spontaneous motility of the uterus isolated from ovariectomized rats. | 1982 | Prostaglandins | pmid:6278538 |
| Knorr A et al. | Cardiostimulating effect of sodium linoleate and its influence on effects of cardiac glycosides. | 1981 | Arch Int Pharmacodyn Ther | pmid:6279044 |
| Huang YS et al. | Most biological effects of zinc deficiency corrected by gamma-linolenic acid (18: 3 omega 6) but not by linoleic acid (18: 2 omega 6). | 1982 | Atherosclerosis | pmid:6279122 |
| De Schrijver R and Privett OS | Effects of dietary long-chain fatty acids on the rat biosynthesis of unsaturated fatty acids in the rat. | 1982 | J. Nutr. | pmid:6279803 |
| Sutherland MW and Gebicki JM | A reaction between the superoxide free radical and lipid hydroperoxide in sodium linoleate micelles. | 1982 | Arch. Biochem. Biophys. | pmid:6282219 |
| Thomas MJ et al. | The role of superoxide in xanthine oxidase-induced autooxidation of linoleic acid. | 1982 | J. Biol. Chem. | pmid:6282880 |
| Gere A | Decrease in essential fatty acid content of edible fats during the frying process. | 1982 | Z Ernahrungswiss | pmid:6293212 |
| Turchetto E and Pignatti C | [Protection of essential fatty acids by vitamin E]. | 1982 | Acta Vitaminol. Enzymol. | pmid:6293292 |
| Rosenthal MD and Whitehurst MC | Selective utilization of omega 6 and omega 3 polyunsaturated fatty acids by human skin fibroblasts. | 1982 | J. Cell. Physiol. | pmid:6294123 |
| Bandyopadhyay GK et al. | Preferential oxidation of linolenic acid compared to linoleic acid in the liver of catfish (Heteropneustes fossilis and Clarias batrachus). | 1982 | Lipids | pmid:6294434 |
| Ookhtens M and Baker N | Incomplete free fatty acid oxidation by ascites tumor cells under low oxygen tension. | 1983 | Am. J. Physiol. | pmid:6295191 |
| Paturneau-Jouas M et al. | Influence of dietary essential fatty acid level on fatty acid composition in peripheral nerve and muscle. | 1982 | Reprod Nutr Dev | pmid:6296946 |
| Shechter Y et al. | Evaluation of factors responsible for the inability of insulin to antagonize lipolysis due to high concentrations of catecholamines. | 1982 | Biochem. Biophys. Res. Commun. | pmid:6297490 |
| Rosenthal MD and Whitehurst MC | Fatty acyl delta 6 desaturation activity of cultured human endothelial cells. Modulation by fetal bovine serum. | 1983 | Biochim. Biophys. Acta | pmid:6297606 |
| Marshall LA and Johnston PV | Modulation of tissue prostaglandin synthesizing capacity by increased ratios of dietary alpha-linolenic acid to linoleic acid. | 1982 | Lipids | pmid:6298554 |
| Bandyopadhyay GK et al. | Evidence for the inability of the catfish Heteropneustes fossilis & Clarias batrachus, to biosynthesize linoleic & linolenic acids. | 1982 | Indian J. Biochem. Biophys. | pmid:6299932 |
| Oliw EH | Oxygenation of linolenic and linoleic acid to novel vicinal dihydroxy acids by hepatic microsomes of the rabbit. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6301473 |
| Frankel EN | Volatile lipid oxidation products. | 1983 | Prog. Lipid Res. | pmid:6306693 |
| Sanders TA | Dietary fat and platelet function. | 1983 | Clin. Sci. | pmid:6309463 |
| Byrne WJ | Intralipid or Liposyn--comparable products? | 1982 | J. Pediatr. Gastroenterol. Nutr. | pmid:6310073 |
| Nemoto N and Takayama S | Effects of unsaturated fatty acids on metabolism of benzo[a]pyrene in an NADPH-fortified rat liver microsomal system. | 1983 | Carcinogenesis | pmid:6311450 |
| Horrobin DF and Manku MS | How do polyunsaturated fatty acids lower plasma cholesterol levels? | 1983 | Lipids | pmid:6312241 |
| Kirstein D et al. | Effect of dietary fats on the delta 6- and delta 5-desaturation of fatty acids in rat liver microsomes. | 1983 | Br. J. Nutr. | pmid:6315055 |
| Baba A et al. | Modulation by unsaturated fatty acids of norepinephrine- and adenosine-induced formation of cyclic AMP in brain slices. | 1984 | J. Neurochem. | pmid:6315886 |
| Høy CE et al. | Acyl group distributions in tissue lipids of rats fed evening primrose oil (gamma -linolenic plus linoleic acid) or soybean oil (alpha-linolenic plus linoleic acid). | 1983 | Lipids | pmid:6318009 |
| Nicholson T and Omer SA | The application of cumulative sum analysis to the investigation of reticulum motility in ruminant animals. | 1983 | Zentralbl Veterinarmed A | pmid:6318476 |
| Spector AA et al. | Eicosapentaenoic acid and prostacyclin production by cultured human endothelial cells. | 1983 | J. Lipid Res. | pmid:6321621 |
| Booyens J et al. | Some effects of linoleic acid and gamma-linolenic acid on the proliferation of human hepatoma cells in culture. | 1984 | S. Afr. Med. J. | pmid:6324395 |
| Kitagawa S et al. | Effects of four types of reagents on ADP-induced aggregation and Ca2+ mobilization of bovine blood platelets. | 1984 | Biochim. Biophys. Acta | pmid:6324876 |
| Simon I et al. | Electron-spin resonance studies of lipid-modified microsomes from Friend erythroleukemia cells. | 1984 | Biochim. Biophys. Acta | pmid:6326852 |
| Singer P et al. | Age-dependent alterations of linoleic, arachidonic and eicosapentaenoic acids in renal cortex and medulla of spontaneously hypertensive rats. | 1984 | Prostaglandins | pmid:6328578 |
| Manku MS et al. | Essential fatty acids in the plasma phospholipids of patients with atopic eczema. | 1984 | Br. J. Dermatol. | pmid:6329254 |
| Badwey JA et al. | Effects of free fatty acids on release of superoxide and on change of shape by human neutrophils. Reversibility by albumin. | 1984 | J. Biol. Chem. | pmid:6330088 |
| Sohal RS et al. | Relationship between lipofuscin granules and polyunsaturated fatty acids in the housefly, Musca domestica. | 1984 | Mech. Ageing Dev. | pmid:6330462 |
| Düsing R et al. | Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. | 1983 | Am. J. Physiol. | pmid:6337507 |
| Linoleic acid, prostaglandin synthesis and chronic renal failure in rats. | 1983 | Nutr. Rev. | pmid:6341898 | |
| Yoshida M et al. | Linoleate and fatty acid compositions in the serum lipids of Japanese patients with multiple sclerosis. | 1983 | Acta Neurol. Scand. | pmid:6364685 |
| Dworkin RH et al. | Linoleic acid and multiple sclerosis: a reanalysis of three double-blind trials. | 1984 | Neurology | pmid:6387534 |
| Singer P et al. | Defective desaturation and elongation of n-6 and n-3 fatty acids in hypertensive patients. | 1984 | Prostaglandins Leukot Med | pmid:6387718 |
| MacDonald ML et al. | Role of linoleate as an essential fatty acid for the cat independent of arachidonate synthesis. | 1983 | J. Nutr. | pmid:6408230 |
| Rustin P et al. | Oxidative interactions between fatty acid peroxy radicals and quinones: possible involvement in cyanide-resistant electron transport in plant mitochondria. | 1983 | Arch. Biochem. Biophys. | pmid:6414377 |
| Anggård E | Ethanol, essential fatty acids and prostaglandins. | 1983 | Pharmacol. Biochem. Behav. | pmid:6415673 |
| Shechter G and Grossman S | Lipoxygenase from baker's yeast: purification and properties. | 1983 | Int. J. Biochem. | pmid:6416906 |
| Laakso S | Inhibition of lipid peroxidation by casein. Evidence of molecular encapsulation of 1,4-pentadiene fatty acids. | 1984 | Biochim. Biophys. Acta | pmid:6419780 |
| Neufeld EJ et al. | A mutant HSDM1C1 fibrosarcoma line selected for defective eicosanoid precursor uptake lacks arachidonate-specific acyl-CoA synthetase. | 1984 | J. Biol. Chem. | pmid:6420417 |
| Cunnane SC et al. | Linoleic acid and arachidonic acid metabolism in human peripheral blood leucocytes: comparison with the rat. | 1984 | Br. J. Nutr. | pmid:6422980 |
| Grossman S et al. | Methylmercuric iodide modification of lipoxygenase-1. Effects on the anaerobic reaction and pigment bleaching. | 1984 | Biochim. Biophys. Acta | pmid:6424722 |
| Inouye S | Site-specific cleavage of double-strand DNA by hydroperoxide of linoleic acid. | 1984 | FEBS Lett. | pmid:6430718 |
| Ramesha CS and Thompson GA | The mechanism of membrane response to chilling. Effect of temperature on phospholipid deacylation and reacylation reactions in the cell surface membrane. | 1984 | J. Biol. Chem. | pmid:6430890 |
| Schick PK et al. | Arachidonate synthesis and uptake in isolated guinea-pig megakaryocytes and platelets. | 1984 | Biochim. Biophys. Acta | pmid:6433984 |
| Kitagawa S et al. | Activation of bovine platelets induced by long-chain unsaturated fatty acids at just below their lytic concentrations, and its mechanism. | 1984 | Biochim. Biophys. Acta | pmid:6435686 |
| Chapkin RS and Ziboh VA | Inability of skin enzyme preparations to biosynthesize arachidonic acid from linoleic acid. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6439197 |
| Tanizawa H et al. | Natural antioxidants. I. Antioxidative components of tea leaf (Thea sinensis L.). | 1984 | Chem. Pharm. Bull. | pmid:6467480 |
| Becker W | Distribution of 14C after oral administration of [1-14C]linoleic acid in rats fed different levels of essential fatty acids. | 1984 | J. Nutr. | pmid:6470826 |
| Iritani N et al. | Physiological impairment in linoleic acid deficiency of rats and the effect of n-3 polyunsaturated fatty acids. | 1984 | J. Nutr. Sci. Vitaminol. | pmid:6470835 |
| Rogiers V et al. | Abnormal fatty acid turnover in the phospholipids of the red blood cell membranes of cystic fibrosis patients (in vitro study). | 1984 | Pediatr. Res. | pmid:6472942 |
| Noble RC et al. | Lipid composition of the bovine epidermis. | 1984 | Res. Vet. Sci. | pmid:6473909 |
| Heine RJ et al. | The effect of dietary linoleic acid and pectin on lipoprotein and apolipoprotein A1 concentrations in rhesus monkeys. | 1984 | Ann. Nutr. Metab. | pmid:6476785 |
| Hennig B et al. | Exposure to free fatty acid increases the transfer of albumin across cultured endothelial monolayers. | 1984 Sep-Oct | Arteriosclerosis | pmid:6477300 |
| Marzouki ZM and Coniglio JG | The effects of hypophysectomy and testosterone treatment on the composition and metabolism of testicular lipids. | 1984 | Lipids | pmid:6482683 |
| Adam O and Wolfram G | Effect of different linoleic acid intakes on prostaglandin biosynthesis and kidney function in man. | 1984 | Am. J. Clin. Nutr. | pmid:6486083 |
| Pratsch L et al. | Interaction of fusogen substances with the erythrocyte membrane. | 1984 | Biomed. Biochim. Acta | pmid:6487285 |
| Jacobs JM and Jacobs NJ | Effect of unsaturated fatty acids on protoporphyrinogen oxidation, a step in heme and chlorophyll synthesis in plant organelles. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6487324 |
| Toda S et al. | [Inhibitory effects of methanol extracts of crude drugs on the air oxidation of linoleic acid]. | 1984 | Yakugaku Zasshi | pmid:6491877 |
| Agnoli GC et al. | [Relation between acute changes in diuresis and renal prostaglandins. I: Induced hypotonic polyuria]. | 1984 | Boll. Soc. Ital. Biol. Sper. | pmid:6497992 |
| Válek J et al. | [Linoleic acid in patients with ischemic heart disease]. | 1984 | Vnitr Lek | pmid:6506507 |
| Reeves VB et al. | Variations in plasma fatty acid concentrations during a one-year self-selected dietary intake study. | 1984 | Am. J. Clin. Nutr. | pmid:6507356 |
| Caponnetto A et al. | [Essential fatty acids for ectodermic organs]. | 1984 | Boll. Soc. Ital. Biol. Sper. | pmid:6518108 |
| Caponnetto A et al. | [Alpha-linolenic acid and its metabolic derivatives in the tissues of rats treated with CCl4]. | 1984 | Boll. Soc. Ital. Biol. Sper. | pmid:6518109 |
| Merzlyak MN and Kovrizhnih VA | Lipid-phenolic radical adducts as a plausible mechanism of "plant ageing" pigment formation. | 1984 | Gen. Physiol. Biophys. | pmid:6530137 |
| Grójec M and Kaleta Z | The composition of fatty acids of the serum and erythrocytes after an alimentary cholesterol load. | 1984 Mar-Apr | Acta Physiol Pol | pmid:6537129 |
| Rüthrich HL et al. | Perinatal linoleate deprivation impairs learning and memory in adult rats. | 1984 | Behav. Neural Biol. | pmid:6539591 |
| Balschun D et al. | Chronobiologic and metabolic characterization of rats fed low or high linoleic acid diets. | 1984 | Biomed. Biochim. Acta | pmid:6542778 |