Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lasa A et al. | Effects of trans-10,cis-12 CLA on liver size and fatty acid oxidation under energy restriction conditions in hamsters. | 2011 | Nutrition | pmid:20619605 |
| Tan B et al. | Dietary L-arginine supplementation differentially regulates expression of lipid-metabolic genes in porcine adipose tissue and skeletal muscle. | 2011 | J. Nutr. Biochem. | pmid:20619625 |
| Yahya A et al. | Effect of J-coupling on lipid composition determination with localized proton magnetic resonance spectroscopy at 9.4 T. | 2011 | J Magn Reson Imaging | pmid:21953706 |
| Cai W et al. | 3,4,4'-Trihydroxy-trans-stilbene, an analogue of resveratrol, is a potent antioxidant and cytotoxic agent. | 2011 | Free Radic. Res. | pmid:21974738 |
| Simon E et al. | Decreasing dietary linoleic acid promotes long chain omega-3 fatty acid incorporation into rat retina and modifies gene expression. | 2011 | Exp. Eye Res. | pmid:21821023 |
| Arawwawala M et al. | In vitro and in vivo evaluation of antioxidant activity of Trichosanthes cucumerina aerial parts. | 2011 | Acta. Biol. Hung. | pmid:21840826 |
| Gorissen L et al. | Linoleate isomerase activity occurs in lactic acid bacteria strains and is affected by pH and temperature. | 2011 | J. Appl. Microbiol. | pmid:21699633 |
| Chen Q et al. | Delta-6 desaturase from borage converts linoleic acid to gamma-linolenic acid in HEK293 cells. | 2011 | Biochem. Biophys. Res. Commun. | pmid:21679695 |
| Yuan Y et al. | [Study on fat-soluble components in different parts of miao ethnomedicine Pileostegia viburnoides by the herbal blitzkrieg extractor]. | 2011 | Zhong Yao Cai | pmid:22500427 |
| Zoia L et al. | Understanding the radical mechanism of lipoxygenases using 31P NMR spin trapping. | 2011 | Bioorg. Med. Chem. | pmid:21474321 |
| Martins SV et al. | Dietary conjugated linoleic acid isomers change the unsaturation degree of hepatic fatty acids in neutral lipids but not in polar lipids. | 2011 | Nutr Res | pmid:21481719 |
| Negrini R and Mezzenga R | pH-responsive lyotropic liquid crystals for controlled drug delivery. | 2011 | Langmuir | pmid:21452814 |
| Liu WM et al. | Effects of linoleic acid and eicosapentaenoic acid on cell proliferation and lipid-metabolism gene expression in primary duck hepatocytes. | 2011 | Mol. Cell. Biochem. | pmid:21274596 |
| Lin X et al. | Dietary conjugated linoleic acid alters long chain polyunsaturated fatty acid metabolism in brain and liver of neonatal pigs. | 2011 | J. Nutr. Biochem. | pmid:21216581 |
| McCusker MM and Grant-Kels JM | Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids. | 2010 Jul-Aug | Clin. Dermatol. | pmid:20620762 |
| NaÄdina VP et al. | [Changes in lipid composition of human plasma and erythrocyte membranes due to sodium hydroxybutyrate and normobaric hyperoxia during bed rest]. | 2010 Jan-Feb | Aviakosm Ekolog Med | pmid:20804001 |
| Zovko Koncić M et al. | Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat. | 2010 Aug-Sep | Food Chem. Toxicol. | pmid:20488218 |
| Hajlaoui H et al. | Chemical composition and biological activities of Tunisian Cuminum cyminum L. essential oil: a high effectiveness against Vibrio spp. strains. | 2010 Aug-Sep | Food Chem. Toxicol. | pmid:20488223 |
| Wang L et al. | [Effects of linoleic acid on intracellular calcium concentration in primarily cultured rat pancreatic β-cells and underlying mechanism]. | 2010 | Sheng Li Xue Bao | pmid:21170499 |
| Bartók T et al. | Identification of the first fumonisin mycotoxins with three acyl groups by ESI-ITMS and ESI-TOFMS following RP-HPLC separation: palmitoyl, linoleoyl and oleoyl EFB₠fumonisin isomers from a solid culture of Fusarium verticillioides. | 2010 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:21108092 |
| Gao F et al. | Quantifying conversion of linoleic to arachidonic and other n-6 polyunsaturated fatty acids in unanesthetized rats. | 2010 | J. Lipid Res. | pmid:20622136 |
| Herdmann A et al. | Effect of dietary n-3 and n-6 PUFA on lipid composition of different tissues of German Holstein bulls and the fate of bioactive fatty acids during processing. | 2010 | J. Agric. Food Chem. | pmid:20597504 |
| Zaman MM et al. | Linoleic acid supplementation results in increased arachidonic acid and eicosanoid production in CF airway cells and in cftr-/- transgenic mice. | 2010 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:20656894 |
| Frangioudakis G et al. | Saturated- and n-6 polyunsaturated-fat diets each induce ceramide accumulation in mouse skeletal muscle: reversal and improvement of glucose tolerance by lipid metabolism inhibitors. | 2010 | Endocrinology | pmid:20660065 |
| Beezhold BL et al. | Vegetarian diets are associated with healthy mood states: a cross-sectional study in seventh day adventist adults. | 2010 | Nutr J | pmid:20515497 |
| Brito GA et al. | Lymphocytes transfer [(14)C]-labeled fatty acids to skeletal muscle in culture; modulation by exercise. | 2010 | Cell Biochem. Funct. | pmid:20517891 |
| Li TL et al. | [Study on the chemical constituents of Humulus scandens]. | 2010 | Zhong Yao Cai | pmid:20518305 |
| Czernichow S et al. | n-6 Fatty acids and cardiovascular health: a review of the evidence for dietary intake recommendations. | 2010 | Br. J. Nutr. | pmid:20522273 |
| Sorrentino F et al. | Impact of linoleic acid supplementation on lovastatin production in Aspergillus terreus cultures. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20571794 |
| Tu WC et al. | Omega-3 long chain fatty acid synthesis is regulated more by substrate levels than gene expression. | 2010 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20573490 |
| Li GY et al. | [Studies on chemistry component and the biological activity of petroleum ether extraction from pre-and post-processed of Cornus officinalis]. | 2010 | Zhong Yao Cai | pmid:20575409 |
| Wei M et al. | [Kinetics of bioconversion of linoleic acid to conjugated linoleic acid by permeabilized Lactobacillus acidophilus cells]. | 2010 | Sheng Wu Gong Cheng Xue Bao | pmid:20575439 |
| Caroprese M et al. | Flaxseed supplementation improves fatty acid profile of cow milk. | 2010 | J. Dairy Sci. | pmid:20494167 |
| Wien M et al. | Decreasing the linoleic acid to alpha-linolenic acid diet ratio increases eicosapentaenoic acid in erythrocytes in adults. | 2010 | Lipids | pmid:20496049 |
| Dailey MJ et al. | Nutrient specific feeding and endocrine effects of jejunal infusions. | 2010 | Obesity (Silver Spring) | pmid:20134410 |
| Combet E et al. | Development of an in vitro system combining aqueous and lipid phases as a tool to understand gastric nitrosation. | 2010 | Rapid Commun. Mass Spectrom. | pmid:20112267 |
| Castellanos P et al. | Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution. | 2010 | Reprod. Toxicol. | pmid:20096347 |
| Coyral-Castel S et al. | Effects of unsaturated fatty acids on progesterone secretion and selected protein kinases in goat granulosa cells. | 2010 | Domest. Anim. Endocrinol. | pmid:20097509 |
| Nakamura T et al. | Excessive fat restriction might promote the recurrence of colorectal tumors. | 2010 | Nutr Cancer | pmid:20099189 |
| Beevi SS et al. | Polyphenolics profile, antioxidant and radical scavenging activity of leaves and stem of Raphanus sativus L. | 2010 | Plant Foods Hum Nutr | pmid:20072818 |
| Privé F et al. | Temperature and duration of heating of sunflower oil affect ruminal biohydrogenation of linoleic acid in vitro. | 2010 | J. Dairy Sci. | pmid:20105542 |
| RodrÃguez AM et al. | Time-course effects of increased fatty acid supply on the expression of genes involved in lipid/glucose metabolism in muscle cells. | 2010 | Cell. Physiol. Biochem. | pmid:20110694 |
| Ivanova L et al. | Phomenins and fatty acids from Alternaria infectoria. | 2010 | Toxicon | pmid:20060014 |
| Won JC et al. | Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha overexpression prevents endothelial apoptosis by increasing ATP/ADP translocase activity. | 2010 | Arterioscler. Thromb. Vasc. Biol. | pmid:19965780 |
| Dimri M et al. | Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells. | 2010 | Carcinogenesis | pmid:19969553 |
| Olveira G et al. | Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis. | 2010 | Arch. Bronconeumol. | pmid:20045240 |
| Jernerén F et al. | Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus. | 2010 | Biochim. Biophys. Acta | pmid:20045744 |
| Paraszkiewicz K et al. | Lipid peroxidation in the fungus Curvularia lunata exposed to nickel. | 2010 | Arch. Microbiol. | pmid:20047047 |
| Esmaeili MA and Sonboli A | Antioxidant, free radical scavenging activities of Salvia brachyantha and its protective effect against oxidative cardiac cell injury. | 2010 | Food Chem. Toxicol. | pmid:20036303 |
| Kubala L et al. | Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation. | 2010 | Free Radic. Biol. Med. | pmid:20156554 |
| Li YF et al. | Properties of synthetic homoisoflavonoids to reduce oxidants and to protect linoleic acid and dna against oxidation. | 2010 | J. Agric. Food Chem. | pmid:20199083 |
| Jernerén F et al. | Linoleate 9R-dioxygenase and allene oxide synthase activities of Aspergillus terreus. | 2010 | Arch. Biochem. Biophys. | pmid:20043865 |
| Gholivand MB et al. | Chemical composition and antioxidant activities of the essential oil and methanol extracts of Psammogeton canescens. | 2010 | Food Chem. Toxicol. | pmid:19748545 |
| Kim BS et al. | Effect of surfactant on the production of oxygenated unsaturated fatty acids by Bacillus megaterium ALA2. | 2010 | N Biotechnol | pmid:19748603 |
| Joshi SC et al. | Antioxidant and antibacterial activities of the leaf essential oils of Himalayan Lauraceae species. | 2010 | Food Chem. Toxicol. | pmid:19766161 |
| Lábaque MC et al. | Effect of age and body weight of Greater Rhea (Rhea americana) females on egg number, size and composition. | 2010 | Br. Poult. Sci. | pmid:21161792 |
| Fekete K and Decsi T | Long-chain polyunsaturated fatty acids in inborn errors of metabolism. | 2010 | Nutrients | pmid:22254065 |
| Alvaro A et al. | Polyunsaturated fatty acids down-regulate in vitro expression of the key intestinal cholesterol absorption protein NPC1L1: no effect of monounsaturated nor saturated fatty acids. | 2010 | J. Nutr. Biochem. | pmid:19443194 |
| Walloschke B et al. | Enrichment of RAW264.7 macrophages with essential 18-carbon fatty acids affects both respiratory burst and production of immune modulating cytokines. | 2010 | J. Nutr. Biochem. | pmid:19447017 |
| Aziz AA et al. | Increasing Dietary alpha-linolenic acid enhances tissue levels of long-chain n-3 PUFA when linoleic acid intake is low in hamsters. | 2010 | Ann. Nutr. Metab. | pmid:20714137 |
| Gutiérrez-Correa J | Trypanosoma cruzi dihydrolipoamide dehydrogenase as target of reactive metabolites generated by cytochrome c/hydrogen peroxide (or linoleic acid hydroperoxide)/phenol systems. | 2010 | Free Radic. Res. | pmid:20815787 |
| Serhan Z et al. | Complete determination of natural site-specific enantio-isotopomeric excesses in linoleic acid using natural abundance deuterium 2D NMR in polypeptide mesophases. | 2010 | Chem. Commun. (Camb.) | pmid:20721385 |
| Noel JT et al. | Specific responses of Salmonella enterica to tomato varieties and fruit ripeness identified by in vivo expression technology. | 2010 | PLoS ONE | pmid:20824208 |
| Macouzet M et al. | Genetic and structural comparison of linoleate isomerases from selected food-grade bacteria. | 2010 | J. Appl. Microbiol. | pmid:20825518 |
| Collin F et al. | Experimental evidence of the reciprocal oxidation of Bovine Serum Albumin and Linoleate in aqueous solution, initiated by HO* free radicals. | 2010 | Biochimie | pmid:20685376 |
| Calder PC | The American Heart Association advisory on n-6 fatty acids: evidence based or biased evidence? | 2010 | Br. J. Nutr. | pmid:21118616 |
| Ramsden CE et al. | n-6 fatty acid-specific and mixed polyunsaturate dietary interventions have different effects on CHD risk: a meta-analysis of randomised controlled trials. | 2010 | Br. J. Nutr. | pmid:21118617 |
| Lu XF et al. | Colorectal cancer cell growth inhibition by linoleic acid is related to fatty acid composition changes. | 2010 | J Zhejiang Univ Sci B | pmid:21121070 |
| Luo H et al. | The In vitro antioxidant properties of chinese highland lichens. | 2010 | J. Microbiol. Biotechnol. | pmid:21124057 |
| Duckett SK and Gillis MH | Effects of oil source and fish oil addition on ruminal biohydrogenation of fatty acids and conjugated linoleic acid formation in beef steers fed finishing diets. | 2010 | J. Anim. Sci. | pmid:20348369 |
| Aluf Y et al. | Specific oxidative stress profile associated with partial striatal dopaminergic depletion by 6-hydroxydopamine as assessed by a novel multifunctional marker molecule. | 2010 | Free Radic. Res. | pmid:20370558 |
| Tume RK et al. | Enriching M. sternomandibularis with alpha-tocopherol by dietary means does not protect against the lipid oxidation caused by high-pressure processing. | 2010 | Meat Sci. | pmid:20374755 |
| Berthelot V et al. | Utilization of extruded linseed to modify fatty composition of intensively-reared lamb meat: effect of associated cereals (wheat vs. corn) and linoleic acid content of the diet. | 2010 | Meat Sci. | pmid:20374762 |
| Della Casa G et al. | Performance and fat quality of heavy pigs fed maize differing in linoleic acid content. | 2010 | Meat Sci. | pmid:20374768 |
| Aldai N et al. | Double-muscling character influences the trans-18:1 and conjugated linoleic acid profiles in concentrate-fed yearling bulls. | 2010 | Meat Sci. | pmid:20374865 |
| Christensen KB et al. | Identification of bioactive compounds from flowers of black elder (Sambucus nigra L.) that activate the human peroxisome proliferator-activated receptor (PPAR) gamma. | 2010 | Phytother Res | pmid:20222152 |
| Chen T et al. | Analytical characterization of Hempseed (seed of Cannabis sativa L.) oil from eight regions in China. | 2010 | J Diet Suppl | pmid:22435611 |
| Xiao C et al. | Synthesis of methyl-substituted xanthotoxol to clarify prooxidant effect of methyl on radical-induced oxidation of DNA. | 2010 | Eur J Med Chem | pmid:20332056 |
| Bitis L et al. | Flavonoids and antioxidant activity of Rosa agrestis leaves. | 2010 | Nat. Prod. Res. | pmid:20397108 |
| Georgiadi A et al. | Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress. | 2010 | Circ. Res. | pmid:20378851 |
| Zulkifli RM et al. | Regulation of ovine and porcine stearoyl coenzyme A desaturase gene promoters by fatty acids and sterols. | 2010 | J. Anim. Sci. | pmid:20382866 |
| DomÃnguez T et al. | Increasing omega-3 desaturase expression in tomato results in altered aroma profile and enhanced resistance to cold stress. | 2010 | Plant Physiol. | pmid:20382895 |
| Kamkar A et al. | The antioxidative effect of Iranian Mentha pulegium extracts and essential oil in sunflower oil. | 2010 | Food Chem. Toxicol. | pmid:20385193 |
| Matsuoka T et al. | Elevated dietary linoleic acid increases gastric carcinoma cell invasion and metastasis in mice. | 2010 | Br. J. Cancer | pmid:20842125 |
| Lau BY et al. | Influence of high-fat diet from differential dietary sources on bone mineral density, bone strength, and bone fatty acid composition in rats. | 2010 | Appl Physiol Nutr Metab | pmid:20962915 |
| Giroix MH et al. | Fatty acid pattern of pancreatic islet lipids in Goto-Kakizaki rats. | 2010 | Endocrine | pmid:20963567 |
| Corriher VA et al. | Pigeon peas as a supplement for lactating dairy cows fed corn silage-based diets. | 2010 | J. Dairy Sci. | pmid:20965347 |
| Liu S and Han B | Differential expression pattern of an acidic 9/13-lipoxygenase in flower opening and senescence and in leaf response to phloem feeders in the tea plant. | 2010 | BMC Plant Biol. | pmid:20969806 |
| Martin H | Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components. | 2010 | Mutat. Res. | pmid:20973164 |
| Brodhun F et al. | PpoC from Aspergillus nidulans is a fusion protein with only one active haem. | 2010 | Biochem. J. | pmid:19878096 |
| Khiaosa-Ard R et al. | Transfer of linoleic and linolenic acid from feed to milk in cows fed isoenergetic diets differing in proportion and origin of concentrates and roughages. | 2010 | J. Dairy Res. | pmid:20482940 |
| Sahoo PK and Behera P | Synthesis and biological screening of some novel amidocarbamate derivatives of ketoprofen. | 2010 | Eur J Med Chem | pmid:20434240 |
| Campoy C et al. | [Update of knowledge, recommendations and full consensus about the role of long chain polyunsaturated fatty acids in pregnancy, lactating period and first year of life.Asociación Española de PediatrÃa. Sociedad Española de GinecologÃa y Obstetricia. Sociedad Española de Nutrición Comunitaria. Academia Española deNutrición y Ciencias de la Alimentación]. | 2010 | Med Clin (Barc) | pmid:20434734 |
| Goicoechea E and Guillen MD | Analysis of hydroperoxides, aldehydes and epoxides by 1H nuclear magnetic resonance in sunflower oil oxidized at 70 and 100 degrees C. | 2010 | J. Agric. Food Chem. | pmid:20438132 |
| Zurabashvili DZ et al. | [The effect of toxic components in tobacco smoke on the fatty acid profile of dental pulp]. | 2010 | Georgian Med News | pmid:20413813 |
| Cannata S et al. | Effect of visual marbling on sensory properties and quality traits of pork loin. | 2010 | Meat Sci. | pmid:20416803 |
| Macouzet M et al. | Genetic and functional aspects of linoleate isomerase in Lactobacillus acidophilus. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20461509 |
| McKay DL et al. | Chronic and acute effects of walnuts on antioxidant capacity and nutritional status in humans: a randomized, cross-over pilot study. | 2010 | Nutr J | pmid:20462428 |
| Salehipour M et al. | Polyunsaturated fatty acids and modulation of cholesterol homeostasis in THP-1 macrophage-derived foam cells. | 2010 | Int J Mol Sci | pmid:21151462 |
| Alloatti A et al. | Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. | 2010 | PLoS ONE | pmid:21151902 |