Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Aneurysm D000783 2 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Circoviridae Infections D018173 2 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Dermatitis, Toxicodendron D011040 3 associated lipids
Infertility D007246 3 associated lipids
Hepatolenticular Degeneration D006527 3 associated lipids
Wasting Syndrome D019282 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Varicose Ulcer D014647 4 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Melanosis D008548 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Dermatitis, Phototoxic D017484 4 associated lipids
Varicocele D014646 4 associated lipids
Biliary Atresia D001656 4 associated lipids
Cicatrix, Hypertrophic D017439 4 associated lipids
Meningeal Neoplasms D008577 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Liu HC et al. Transcriptome changes in Polygonum multiflorum Thunb. roots induced by methyl jasmonate. 2015 J Zhejiang Univ Sci B pmid:26642186
Liang S et al. Physicochemical Properties and Fatty Acid Profiles of Elaeagnus mollis Diels Nut Oils. 2015 J Oleo Sci pmid:26632946
Qian Z et al. Mulberry fruit prevents LPS-induced NF-κB/pERK/MAPK signals in macrophages and suppresses acute colitis and colorectal tumorigenesis in mice. 2015 Sci Rep pmid:26615818
Lee CW et al. Structural basis for the ligand-binding specificity of fatty acid-binding proteins (pFABP4 and pFABP5) in gentoo penguin. 2015 Biochem. Biophys. Res. Commun. pmid:26206084
Salehi R et al. A prepartum diet supplemented with oilseeds high in oleic or linoleic acid reduced GnRH-induced LH release in dairy cows during second week postpartum. 2015 Reprod. Biol. Endocrinol. pmid:26138920
Grevengoed TJ et al. Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. 2015 J. Lipid Res. pmid:26136511
Hasiewicz-Derkacz K et al. Natural phenolics greatly increase flax (Linum usitatissimum) oil stability. 2015 BMC Biotechnol. pmid:26123633
Askari M et al. Tissue fatty acid composition and secretory phospholipase-A2 activity in oral squamous cell carcinoma. 2015 Clin Transl Oncol pmid:25351172
Jones PJ et al. High-oleic canola oil consumption enriches LDL particle cholesteryl oleate content and reduces LDL proteoglycan binding in humans. 2015 Atherosclerosis pmid:25528432
Miyamoto J et al. A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway. 2015 J. Biol. Chem. pmid:25505251