Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Brain Edema D001929 20 associated lipids
Breast Neoplasms D001943 24 associated lipids
Cachexia D002100 21 associated lipids
Carcinoma D002277 18 associated lipids
Carcinoma, Krebs 2 D002287 1 associated lipids
Cattle Diseases D002418 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Brain Ischemia D002545 89 associated lipids
Uterine Cervical Neoplasms D002583 10 associated lipids
Cholestasis D002779 23 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Constipation D003248 8 associated lipids
Coronary Disease D003327 70 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Deficiency Diseases D003677 12 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Dermatitis D003872 30 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Otsuka H et al. [Studies on anti-inflammatory agents. IV. Anti-inflammatory constituents from roots of Panax ginseng C.A. Meyer (author's transl)]. 1981 Yakugaku Zasshi pmid:7338798
Osaki Y et al. [Antimutagenic and bactericidal substances in the fruit body of a Basidiomycete Agaricus blazei, Jun-17]. 1994 Yakugaku Zasshi pmid:8014843
Yamamoto K et al. [Antimutagenic substances in the Armeniacae semen and Persicae semen]. 1992 Yakugaku Zasshi pmid:1294719
Fujii M Pathogenesis of Diet-induced Atopic Dermatitis in Hairless Mice. 2017 Yakugaku Zasshi pmid:28049895
Byczkowski JZ and Kulkarni AP Linoleate-dependent co-oxygenation of benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol by rat cytosolic lipoxygenase. 1992 Xenobiotica pmid:1413876
Cardoso CR et al. Influence of topical administration of n-3 and n-6 essential and n-9 nonessential fatty acids on the healing of cutaneous wounds. 2004 Mar-Apr Wound Repair Regen pmid:15086775
Dubnov G and Berry EM Omega-6/omega-3 fatty acid ratio: the Israeli paradox. 2003 World Rev Nutr Diet pmid:14579685
Zampelas A et al. Linoleic acid to alpha-linolenic acid ratio. From clinical trials to inflammatory markers of coronary artery disease. 2003 World Rev Nutr Diet pmid:14579686
Hamazaki T and Okuyama H The Japan Society for Lipid Nutrition recommends to reduce the intake of linoleic acid. A review and critique of the scientific evidence. 2003 World Rev Nutr Diet pmid:14579687
Budowski P et al. Mature milk from Israeli mothers is rich in polyunsaturated fatty acids. 1994 World Rev Nutr Diet pmid:7871809
Postle AD et al. Molecular species composition of plasma phosphatidylcholine in human pregnancy. 1994 World Rev Nutr Diet pmid:7871810
Yavin E and Green P Distribution, processing and selective esterification of essential fatty acid metabolites in the fetal brain. 1994 World Rev Nutr Diet pmid:7871815
Lien EL The ratio of linoleic acid to alpha-linolenic acid in infant formulas: current facts and future research directions. 1994 World Rev Nutr Diet pmid:7871839
Simopoulos AP Evolutionary aspects of the dietary omega-6:omega-3 fatty acid ratio: medical implications. 2009 World Rev Nutr Diet pmid:19696523
Watkins BA et al. Designed eggs containing conjugated linoleic acids and omega-3 polyunsaturated fatty acids. 2001 World Rev Nutr Diet pmid:11545041
Okuyama H et al. Omega3 fatty acids effectively prevent coronary heart disease and other late-onset diseases--the excessive linoleic acid syndrome. 2007 World Rev Nutr Diet pmid:17167282
Okuyama H et al. Why isn't the causal relationship between linoleic acid and mortalities from coronary heart disease and stroke revealed by clinical studies? 2007 World Rev Nutr Diet pmid:17167283
Okuyama H et al. Mechanisms by which dietary fats affect coronary heart disease mortality. 2007 World Rev Nutr Diet pmid:17167284
Okuyama H et al. Cancers common in the USA are stimulated by omega 6 fatty acids and large amounts of animal fats, but suppressed by omega 3 fatty acids and cholesterol. 2007 World Rev Nutr Diet pmid:17167285
Okuyama H and Sakai K Effects of dietary oils with extreme omega 3/omega 6 ratios--selective incorporation and differential catabolism. 1991 World Rev Nutr Diet pmid:1675826