Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Brain Edema D001929 20 associated lipids
Breast Neoplasms D001943 24 associated lipids
Cachexia D002100 21 associated lipids
Carcinoma D002277 18 associated lipids
Carcinoma, Krebs 2 D002287 1 associated lipids
Cattle Diseases D002418 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Brain Ischemia D002545 89 associated lipids
Uterine Cervical Neoplasms D002583 10 associated lipids
Cholestasis D002779 23 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Constipation D003248 8 associated lipids
Coronary Disease D003327 70 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Deficiency Diseases D003677 12 associated lipids
Demyelinating Diseases D003711 15 associated lipids
Dermatitis D003872 30 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Yehuda S et al. Fatty acids and brain peptides. 1998 Peptides pmid:9493877
Bremmer DR et al. Effects of chain length and unsaturation of fatty acid mixtures infused into the abomasum of lactating dairy cows. 1998 J. Dairy Sci. pmid:9493093
Ramesh G and Das UN Effect of cis-unsaturated fatty acids on Meth-A ascitic tumour cells in vitro and in vivo. 1998 Cancer Lett. pmid:9489490
Bogdanov KY et al. Modulation of the transient outward current in adult rat ventricular myocytes by polyunsaturated fatty acids. 1998 Am. J. Physiol. pmid:9486261
Pareja A et al. Unsaturated fatty acids alter the insulin secretion response of the islets of Langerhans in vitro. 1997 Diabetes Res. Clin. Pract. pmid:9483379
Chisholm A et al. A diet rich in walnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic subjects. 1998 Eur J Clin Nutr pmid:9481526
Iwase H et al. Calcium ions potentiate lipoxygenase activity of cytochrome c at the physiological pH. 1998 Biochem. Biophys. Res. Commun. pmid:9480835
Agostoni C et al. Low levels of linoleic acid in plasma total lipids of HIV-1 seropositive children. 1998 J Am Coll Nutr pmid:9477386
Bouwstra JA et al. Role of ceramide 1 in the molecular organization of the stratum corneum lipids. 1998 J. Lipid Res. pmid:9469597
Pomposiello SI et al. Linoleic acid induces relaxation and hyperpolarization of the pig coronary artery. 1998 Hypertension pmid:9461230
Herbel BK et al. Safflower oil consumption does not increase plasma conjugated linoleic acid concentrations in humans. 1998 Am. J. Clin. Nutr. pmid:9459383
Devor DC and Frizzell RA Modulation of K+ channels by arachidonic acid in T84 cells. II. Activation of a Ca(2+)-independent K+ channel. 1998 Am. J. Physiol. pmid:9458723
Dadras SS et al. Implication of hydrogen peroxide generation and apoptosis in the neoplastic transformation of mouse fibroblasts overexpressing peroxisomal fatty acyl-CoA oxidase. 1998 Int. J. Oncol. pmid:9454884
van Roermund CW et al. Peroxisomal beta-oxidation of polyunsaturated fatty acids in Saccharomyces cerevisiae: isocitrate dehydrogenase provides NADPH for reduction of double bonds at even positions. 1998 EMBO J. pmid:9450993
Maheswari SU et al. Inhibition of Fe(II) catalyzed linoleic acid oxidation and DNA damage by phosvitin. 1997 Mol. Cell. Biochem. pmid:9450644
Colquhoun A and Curi R Regulation of tumour cell fatty acid oxidation by n-6 polyunsaturated fatty acids. 1997 Biochem. Soc. Trans. pmid:9450108
Hamberg M Stereochemistry of oxygenation of linoleic acid catalyzed by prostaglandin-endoperoxide H synthase-2. 1998 Arch. Biochem. Biophys. pmid:9448728
Berry H et al. Oxygen concentration determines regiospecificity in soybean lipoxygenase-1 reaction via a branched kinetic scheme. 1998 J. Biol. Chem. pmid:9446584
Kaur K et al. (Carboxyalkyl)pyrroles in human plasma and oxidized low-density lipoproteins. 1997 Chem. Res. Toxicol. pmid:9437530
Bylund J et al. Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes. 1998 J. Pharmacol. Exp. Ther. pmid:9435160