Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

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Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Atherosclerosis D050197 85 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Mucositis D052016 7 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Refeeding Syndrome D055677 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Kataoka K et al. [A rat model of chronic pancreatic insufficiency induced by injection of zein-oleic acid-linoleic acid solution into the pancreatic duct]. 1988 Nihon Shokakibyo Gakkai Zasshi pmid:3184515
Pepin D et al. Essential fatty acid pattern of glycerolipids in rat hepatocytes in primary culture and in coculture with rat liver epithelial cells. 1988 Lipids pmid:3185111
Takahashi R and Horrobin DF Linoleic acid-induced fatty acid changes in platelet and aorta of the rat: effect of age and cholesterol. 1988 Lipids pmid:3185125
Kurinami S et al. Effects of polyunsaturated fatty acids and/or lecithin on the plasma concentrations of very low density lipoprotein-tryglyceride (VLDL) and ketone bodies in humans. 1988 Kurume Med J pmid:3193745
Babin F et al. Plasma fatty acid composition and lipid peroxide levels in children with paucity of interlobular bile ducts. 1988 Ann. Nutr. Metab. pmid:3195990
Høy CE and Hølmer G Dietary linoleic acid and the fatty acid profiles in rats fed partially hydrogenated marine oils. 1988 Lipids pmid:3200121
Hubbard NE et al. Inhibition of growth and linoleate-enhanced metastasis of a transplantable mouse mammary tumor by indomethacin. 1988 Cancer Lett. pmid:3203321
Kulkarni AP and Cook DC Hydroperoxidase activity of lipoxygenase: a potential pathway for xenobiotic metabolism in the presence of linoleic acid. 1988 Res. Commun. Chem. Pathol. Pharmacol. pmid:3141996
Shimokawa T et al. Effect of dietary alpha-linolenate/linoleate balance on mean survival time, incidence of stroke and blood pressure of spontaneously hypertensive rats. 1988 Life Sci. pmid:2905408
Rey HG et al. Two-sided functional Na,K-ATPase-liposomes for characterizing the permeability and side of action of pump inhibitors. 1988 Prog. Clin. Biol. Res. pmid:2906133
Singh B et al. Effect of high/low dietary linoleic acid levels on the function and fatty acid composition of T-lymphocytes of normal and diabetic rats. 1988 Diabetes Res. pmid:3265900
Perisho K et al. Fatty acids of acylceramides from comedones and from the skin surface of acne patients and control subjects. 1988 J. Invest. Dermatol. pmid:2964492
Dietary fat and insulin receptor function in rat adipocytes. 1988 Nutr. Rev. pmid:3277091
Collier A et al. Reduced free radical activity detected by decreased diene conjugates in insulin-dependent diabetic patients. 1988 Diabet. Med. pmid:2975566
Bartels T et al. [Effect of linoleic acid in food on spongioid bone density and prostaglandin biosynthesis in bones]. 1988 Beitr Orthop Traumatol pmid:3228436
Stephens RJ et al. Lipid peroxidation and retinal phototoxic degeneration. 1988 Basic Life Sci. pmid:2977946
Whitehead CC and Herron KM Fatty acid requirements of breeding turkeys. 1988 Br. Poult. Sci. pmid:3233502
Parsons HG et al. Supplemental calories improve essential fatty acid deficiency in cystic fibrosis patients. 1988 Pediatr. Res. pmid:3211621
Solakivi T et al. Plasma apolipoprotein B in middle-aged Finnish men. Evidence for a regional gradient of apo B and lack of negative correlation between apo B and dietary linoleate in hyperapobetalipoproteinemia. 1988 Atherosclerosis pmid:3214459
Schächtele C et al. Stimulus-dependent inhibition of platelet aggregation by the protein kinase C inhibitors polymyxin B, H-7 and staurosporine. 1988 Biochem. Biophys. Res. Commun. pmid:2831891
Loesberg C et al. Superoxide anion production by alveolar macrophages of guinea pigs fed different diets in a model of atopy. 1988 Agents Actions pmid:2833083
Garg ML et al. Differential effects of dietary linoleic and alpha-linolenic acid on lipid metabolism in rat tissues. 1988 Lipids pmid:2903427
Choi YS and Sugano M Effects of dietary alpha- and gamma-linolenic acid on lipid metabolism in young and adult rats. 1988 Ann. Nutr. Metab. pmid:2903713
Manku MS et al. Changes in human plasma essential fatty acid levels as a result of administration of linoleic acid and gamma-linolenic acid. 1988 Eur J Clin Nutr pmid:2836190
Venkatraman JT and Clandinin MT Ribonucleic acid efflux from isolated mouse liver nuclei is altered by diet and genotypically determined change in nuclear envelope composition. 1988 Biochim. Biophys. Acta pmid:2452656
MacKenzie LW et al. Prostacyclin biosynthesis by cultured human myometrial smooth muscle cells: dependency on arachidonic or linoleic acid in the culture medium. 1988 Am. J. Obstet. Gynecol. pmid:3144917
Wooten MW and Wrenn RW Linoleic acid is a potent activator of protein kinase C type III-alpha isoform in pancreatic acinar cells; its role in amylase secretion. 1988 Biochem. Biophys. Res. Commun. pmid:2454109
Benadé AJ et al. Plasma low density lipoprotein composition in relation to atherosclerosis in nutritionally defined Vervet monkeys. 1988 Atherosclerosis pmid:3145748
Bakalova RA et al. [A mechanism of the inhibitory effect of alpha-tocopherol and its synthetic analogs on the oxidation of linoleic acid catalyzed by lipoxygenase from reticulocytes]. 1988 Dokl. Akad. Nauk SSSR pmid:3135162
MacGilchrist AJ et al. Abetalipoproteinaemia in adults: role of vitamin therapy. 1988 J. Inherit. Metab. Dis. pmid:3139930
Innis SM and Yuen DE Microsomal desaturation-elongation of linoleic acid following parenteral feeding with lipid emulsions in the rat. 1988 Lipids pmid:3139951
Palmblad J and Gyllenhammar H Effect of dietary lipids on immunity and inflammation. Review article. 1988 APMIS pmid:2841953
Albro PW et al. Comparison of the effects of carbon tetrachloride and of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the disposition of linoleic acid in rat liver in vitro. 1988 Chem. Biol. Interact. pmid:3135123
Craven PA and DeRubertis FR Role of activation of protein kinase C in the stimulation of colonic epithelial proliferation by unsaturated fatty acids. 1988 Gastroenterology pmid:3135225
Nakagawa Y and Waku K Selective inhibition of free arachidonic acid production in activated alveolar macrophages by calmodulin antagonists. 1988 Biochem. Biophys. Res. Commun. pmid:3142466
Rafael J et al. Effect of dietary linoleic acid and essential fatty acid deficiency on resting metabolism, nonshivering thermogenesis and brown adipose tissue in the rat. 1988 J. Nutr. pmid:3367242
Simpson LO The etiopathogenesis of premenstrual syndrome as a consequence of altered blood rheology: a new hypothesis. 1988 Med. Hypotheses pmid:3367811
Behrends W et al. The glyoxysomal beta-oxidation system in cucumber seedlings: identification of enzymes required for the degradation of unsaturated fatty acids. 1988 Arch. Biochem. Biophys. pmid:3369861
Lindström P and Palmblad J Dietary linoleic acid and rat neutrophil adhesion and chemotaxis. 1988 J Clin Lab Immunol pmid:3373519
Schauder P et al. [The effect of free fatty acids on the leucine oxidation of human lymphocytes]. 1988 Beitr Infusionther Klin Ernahr pmid:3377747
Kawooya JK and Law JH Role of lipophorin in lipid transport to the insect egg. 1988 J. Biol. Chem. pmid:3379043
Bester R and Lochner A Sarcolemmal phospholipid fatty acid composition and permeability. 1988 Biochim. Biophys. Acta pmid:3382645
Hiramatsu N et al. Effects of dose levels of autoxidized linoleic acid on the drug-metabolizing system in rat liver. 1988 J. Nutr. Sci. Vitaminol. pmid:3392612
Sugiyama S et al. The role of leukotoxin (9,10-epoxy-12-octadecenoate) in the genesis of coagulation abnormalities. 1988 Life Sci. pmid:3398695
Jager FC Vitamin E. 1988 Vet. Rec. pmid:3407122
Asciutti-Moura LS et al. Fatty acid composition of serum lipids and its relation to diet in an elderly institutionalized population. 1988 Am. J. Clin. Nutr. pmid:3421207
Griffiths G et al. Delta 6- and delta 12-desaturase activities and phosphatidic acid formation in microsomal preparations from the developing cotyledons of common borage (Borago officinalis). 1988 Biochem. J. pmid:3421914
Casteels M et al. Inhibition of 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid oxidation and of bile acid secretion in rat liver by fatty acids. 1988 J. Biol. Chem. pmid:3350807
Kato K et al. Studies on scavengers of active oxygen species. 1. Synthesis and biological activity of 2-O-alkylascorbic acids. 1988 J. Med. Chem. pmid:3351858
Shasby DM et al. Oxidants and conductance of cultured epithelial cell monolayers: inositol phospholipid hydrolysis. 1988 Am. J. Physiol. pmid:3144179
Crandall DL et al. Effect of varying concentrations of linoleic acid on alpha-adrenoceptor responses in spontaneously hypertensive rats. 1988 Prostaglandins Leukot. Essent. Fatty Acids pmid:2845438
Norman A et al. Postirradiation protection of chromosomes by linoleate. 1988 Int. J. Radiat. Biol. pmid:2902149
Spector R Fatty acid transport through the blood-brain barrier. 1988 J. Neurochem. pmid:3335863
Das UN Effect of phorbolmyristate acetate on fatty acid uptake and distribution in human promyelocytic leukemia (HL-60) cells in vitro. 1988 Biochem. Biophys. Res. Commun. pmid:3144272
Reynolds CH Inactivation of soybean lipoxygenase by lipoxygenase inhibitors in the presence of 15-hydroperoxyeicosatetraenoic acid. 1988 Biochem. Pharmacol. pmid:3144281
Chander A and Fisher AB Choline-phosphate cytidyltransferase activity and phosphatidylcholine synthesis in rat granular pneumocytes are increased with exogenous fatty acids. 1988 Biochim. Biophys. Acta pmid:2893643
Bordet JC et al. Hydroperoxides produced by n-6 lipoxygenation of arachidonic and linoleic acids potentiate synthesis of prostacyclin related compounds. 1988 Biochim. Biophys. Acta pmid:3124885
Sebokova E et al. Modulation of receptor-mediated gonadotropin action in rat testes by dietary fat. 1988 Am. J. Physiol. pmid:2897795
Fukuzawa K et al. Site-specific induction of lipid peroxidation by iron in charged micelles. 1988 Arch. Biochem. Biophys. pmid:2829725
Hashimoto A et al. [Effect of dietary alpha-linolenate/linoleate balance on the formation of leukotrienes in rat polymorphonuclear leukocytes]. 1988 Arerugi pmid:2901255
Markov KhM et al. [Effect of dietary linoleic acid on the platelet aggregation, fatty acid composition of platelet phospholipids and synthesis of platelet prostaglandins in rats]. 1988 Jul-Aug Vopr. Med. Khim. pmid:3195130
Ghisolfi J et al. Metabolic utilization of linoleic acid from fat emulsion in infants during total parenteral nutrition. 1988 Jul-Aug JPEN J Parenter Enteral Nutr pmid:3138449
Cotter R et al. Fatty acid profiles in response to soybean oil lipid emulsion infusions in essential fatty acid-deficient miniature swine. 1988 Mar-Apr JPEN J Parenter Enteral Nutr pmid:3129587
Markov KhM and Kucherenko AG [Effect of diets with various contents of linoleic acid on the prostaglandin system in the rat kidney]. 1988 Mar-Apr Vopr. Med. Khim. pmid:3400199
Clark RM Lack of correlation between changes in the concentrations of linoleate and arachidonate in human milk relative to total milk lipid. 1988 Nov-Dec J. Pediatr. Gastroenterol. Nutr. pmid:3143822
Kageyama K et al. Synergistic inhibition of DNA synthesis in Ehrlich ascites tumour cells by a combination of unsaturated fatty acids and hyperthermia. 1989 J Appl Toxicol pmid:2926093
Booker ML et al. Effect of dietary cholesterol on phosphatidylcholines and phosphatidylethanolamines in bile and gallbladder mucosa in the prairie dog. 1989 Gastroenterology pmid:2507386
Fairbank J et al. Octadeca-9,11-dienoic acid in cervical intraepithelial neoplasia: a colposcopic study. 1989 Clin. Chim. Acta pmid:2612010
Park JH et al. Effects of dietary linoleic acid on mucosal adaptation after small bowel resection. 1989 Digestion pmid:2612750
Hiramatsu N et al. Effects of dietary pantethine levels on drug-metabolizing system in the liver of rats orally administered varying amounts of autoxidized linoleate. 1989 J. Nutr. Sci. Vitaminol. pmid:2585150
Chanussot B et al. Liver microsomal delta 6 and delta 5 linoleic acid desaturation in female BB rats. 1989 Diabetologia pmid:2591647
Clouet P et al. Pathway of alpha-linolenic acid through the mitochondrial outer membrane in the rat liver and influence on the rate of oxidation. Comparison with linoleic and oleic acids. 1989 Biochem. J. pmid:2597132
Bayorh MA et al. Acute and chronic effects of eicosapentaenoic acid (EPA) on the cardiovascular system. 1989 Res. Commun. Chem. Pathol. Pharmacol. pmid:2558405
Meikle AW et al. Nonesterified fatty acids modulate steroidogenesis in mouse Leydig cells. 1989 Am. J. Physiol. pmid:2558577
Hennig B and Watkins BA Linoleic acid and linolenic acid: effect on permeability properties of cultured endothelial cell monolayers. 1989 Am. J. Clin. Nutr. pmid:2563626
Madison KC et al. Murine keratinocyte cultures grown at the air/medium interface synthesize stratum corneum lipids and "recycle" linoleate during differentiation. 1989 J. Invest. Dermatol. pmid:2473131
Kurganov BI et al. Kinetics of soybean lipoxygenase reaction in hydrated reversed micelles. 1989 Biochimie pmid:2474334
Anderson GJ and Connor WE On the demonstration of omega-3 essential-fatty-acid deficiency in humans. 1989 Am. J. Clin. Nutr. pmid:2494878
Byczkowski JZ and Kulkarni AP Lipoxygenase-catalyzed epoxidation of benzo(a)pyrene-7,8-dihydrodiol. 1989 Biochem. Biophys. Res. Commun. pmid:2494999
Kaduce TL et al. Formation of 9-hydroxyoctadecadienoic acid from linoleic acid in endothelial cells. 1989 J. Biol. Chem. pmid:2496121
Hamazaki S et al. Oxygen reduction and lipid peroxidation by iron chelates with special reference to ferric nitrilotriacetate. 1989 Arch. Biochem. Biophys. pmid:2500058
Imaizumi K et al. Effect of phosphatidylethanolamine and its constituent base on the metabolism of linoleic acid in rat liver. 1989 Biochim. Biophys. Acta pmid:2508745
Buchanan MR et al. Vessel wall reactivity and 13-hydroxy-octadecadienoic acid synthesis. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526487
Lokesh BR et al. The suppression of eicosanoid synthesis by peritoneal macrophages is influenced by the ratio of dietary docosahexaenoic acid to linoleic acid. 1989 Lipids pmid:2528666
Matsuzaki A et al. Mechanism of selective killing by dilinoleoylglycerol of cells transformed by the E1A gene of adenovirus type 12. 1989 Cancer Res. pmid:2529026
Furth EE et al. The effect of endogenous essential and nonessential fatty acids on the uptake and subsequent agonist-induced release of arachidonate. 1989 J. Biol. Chem. pmid:2553711
Hansen O Characterization of fatty acid interaction with ouabain and vanadate binding to (Na+ + K+)-activated ATPase. 1989 Biochim. Biophys. Acta pmid:2554979
Blond JP et al. Effect of fenofibrate treatment on linoleic acid desaturation in liver of obese Zucker rats. 1989 Biochem. Pharmacol. pmid:2764996
Hrboticky N et al. Effect of linoleic acid-rich infant formula feeding on brain synaptosomal lipid accretion and enzyme thermotropic behavior in the piglet. 1989 J. Lipid Res. pmid:2769072
Zhu YP et al. Growth-inhibition effects of oleic acid, linoleic acid, and their methyl esters on transplanted tumors in mice. 1989 J. Natl. Cancer Inst. pmid:2769782
Braughler JM and Pregenzer JF The 21-aminosteroid inhibitors of lipid peroxidation: reactions with lipid peroxyl and phenoxy radicals. 1989 Free Radic. Biol. Med. pmid:2806938
Hrelia S et al. Age-related changes in linoleate and alpha-linolenate desaturation by rat liver microsomes. 1989 Biochem. Biophys. Res. Commun. pmid:2570573
Bolton-Smith C et al. The effect of dietary linoleic acid on rat platelet sialic acid. 1989 Biochim. Biophys. Acta pmid:2775771
Toda S et al. Peroxidation of linoleic acid induced by interaction with haemoglobin and hydrogen peroxide. 1989 Free Radic. Res. Commun. pmid:2806947
Rosing U and Olund A Endometrial content of prostaglandin precursors during the menstrual cycle. 1989 Prostaglandins Leukot. Essent. Fatty Acids pmid:2780764
Blanken R et al. Effect of mineral oil and linoleic-acid-containing emulsions on the skin vapour loss of sodium-lauryl-sulphate-induced irritant skin reactions. 1989 Contact Derm. pmid:2706971
Zevenbergen JL and Houtsmuller UM Effect of dietary fats on linoleic acid metabolism. A radiolabel study in rats. 1989 Biochim. Biophys. Acta pmid:2713382
Chapkin RS et al. Linoleic acid metabolism in metastatic and nonmetastatic murine mammary tumor cells. 1989 Cancer Res. pmid:2503244
Diehl AK et al. Dietary intake and the prevalence of gallbladder disease in Mexican Americans. 1989 Gastroenterology pmid:2583417
Szamel M et al. Activation signals in human lymphocytes. Incorporation of polyunsaturated fatty acids into plasma membrane phospholipids regulates IL-2 synthesis via sustained activation of protein kinase C. 1989 J. Immunol. pmid:2530278