| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leptospirosis | D007922 | 2 associated lipids |
| Genetic Diseases, X-Linked | D040181 | 2 associated lipids |
| Lactose Intolerance | D007787 | 2 associated lipids |
| Dermatitis, Toxicodendron | D011040 | 3 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Wasting Syndrome | D019282 | 3 associated lipids |
| Haemophilus Infections | D006192 | 3 associated lipids |
| Hepatolenticular Degeneration | D006527 | 3 associated lipids |
| Pneumonia, Viral | D011024 | 3 associated lipids |
| Pregnancy Complications, Neoplastic | D011252 | 4 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| MEAD JF et al. | Metabolism of the essential fatty acids. II. The metabolism of stearate, oleate, and linoleate by fat-deficient and normal mice. | 1956 | J. Biol. Chem. | pmid:13278347 |
| pmid:13272072 | ||||
| Fukuzawa K and Fujii T | Peroxide dependent and independent lipid peroxidation: site-specific mechanisms of initiation by chelated iron and inhibition by alpha-tocopherol. | 1992 | Lipids | pmid:1326073 |
| Britton M et al. | Diet as a source of phospholipid esterified 9,11-octadecadienoic acid in humans. | 1992 | Clin. Sci. | pmid:1325328 |
| Jannace PW et al. | Effects of oral soy phosphatidylcholine on phagocytosis, arachidonate concentrations, and killing by human polymorphonuclear leukocytes. | 1992 | Am. J. Clin. Nutr. | pmid:1323926 |
| PRIVETT OS et al. | Polyethenoid fatty acid metabolism. VIII. Nonpotency of cis-9, trans-12-linoleate as essential fatty acid. | 1955 | Arch. Biochem. Biophys. | pmid:13239196 |
| BIOLOGIC utilization of fatty acid isomers. | 1955 | Nutr. Rev. | pmid:13236187 | |
| Kang JX et al. | The chloride channel blocker anthracene 9-carboxylate inhibits fatty acid incorporation into phospholipid in cultured human airway epithelial cells. | 1992 | Biochem. J. | pmid:1323271 |
| BLOMSTRAND R | The intestinal absorption of linoleic-1-14C acid. | 1954 | Acta Physiol. Scand. | pmid:13228101 |
| BUSINCO L | [Vitamin F in the therapy of various allergic syndromes and hepatopathies]. | 1954 | Ther Umsch | pmid:13226237 |
| Winterbourn CC et al. | Chlorohydrin formation from unsaturated fatty acids reacted with hypochlorous acid. | 1992 | Arch. Biochem. Biophys. | pmid:1321589 |
| BUSINCO L | [Vitamin F in therapy of allergic syndromes and liver diseases]. | 1954 | Ned Tijdschr Geneeskd | pmid:13203632 |
| IRRADIATION effects on linoleate oxidation. | 1954 | Nutr. Rev. | pmid:13194241 | |
| PASQUALI W | [Determination of arachidonic, linolenic and linoleic (vitamin F) acid in milk and blood. II. Determination in the milk]. | 1954 | Acta Vitaminol | pmid:13171149 |
| Huang SC et al. | Dietary fat influences Ia antigen expression and immune cell populations in the murine peritoneum and spleen. | 1992 | J. Nutr. | pmid:1316956 |
| Matsumoto M et al. | D-galactosamine-induced cell damage enhances specific binding of prostaglandin E1 to rat hepatocytes. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1315527 |
| Byczkowski JZ and Kulkarni AP | Vanadium redox cycling, lipid peroxidation and co-oxygenation of benzo(a)pyrene-7,8-dihydrodiol. | 1992 | Biochim. Biophys. Acta | pmid:1315157 |
| Kalyanaraman B et al. | Synergistic interaction between the probucol phenoxyl radical and ascorbic acid in inhibiting the oxidation of low density lipoprotein. | 1992 | J. Biol. Chem. | pmid:1313022 |
| Hsu JM and Ding ST | Effect of polyunsaturated fatty acids on the expression of transcription factor adipocyte determination and differentiation-dependent factor 1 and of lipogenic and fatty acid oxidation enzymes in porcine differentiating adipocytes. | 2003 | Br. J. Nutr. | pmid:13129455 |
| Kelly O et al. | The effect of polyunsaturated fatty acids, including conjugated linoleic acid, on calcium absorption and bone metabolism and composition in young growing rats. | 2003 | Br. J. Nutr. | pmid:13129442 |
| Tanaka N et al. | Antioxidative capacity of extracts and constituents in Cornus capitata adventitious roots. | 2003 | J. Agric. Food Chem. | pmid:13129293 |
| Albro PW et al. | Isolation and characterization of the initial radical adduct formed from linoleic acid and alpha-(4-pyridyl 1-oxide)-N-tert-butylnitrone in the presence of soybean lipoxygenase. | 1992 | Chem. Biol. Interact. | pmid:1312396 |
| Dwight JF et al. | Membrane incorporation of non-esterified fatty acids and effects on the sodium pump of human erythrocytes. | 1992 | Clin. Sci. | pmid:1310925 |
| Allgayer H et al. | Superoxide, hydroxyl and fatty acid radical scavenging by aminosalicylates. Direct evaluation with electron spin resonance spectroscopy. | 1992 | Biochem. Pharmacol. | pmid:1310851 |
| Cleland LG et al. | Linoleate inhibits EPA incorporation from dietary fish-oil supplements in human subjects. | 1992 | Am. J. Clin. Nutr. | pmid:1310374 |
| BUTCHER EO | The penetration of fat and fatty acid into the skin of the rat. | 1953 | J. Invest. Dermatol. | pmid:13069840 |
| MARTINET M | [Vitamin F deficiency and hemorrhages in the rat embryo]. | 1953 | Arch. Fr. Pediatr. | pmid:13058451 |
| TAPPEL AL | The mechanism of the oxidation of unsaturated fatty acids catalyzed by hematin compounds. | 1953 | Arch. Biochem. Biophys. | pmid:13058395 |
| KHAN NA | Biological oxidation. I. The infrared studies on the lipoxidasecatalyzed oxidation of linoleic acid. | 1953 | Arch. Biochem. Biophys. | pmid:13058378 |
| DE SURVILLE B | [The polymerization of linoleic acid]. | 1952 | C. R. Hebd. Seances Acad. Sci. | pmid:13033139 |
| TAPPEL AL et al. | Effect of temperature and antioxidants upon the lipoxidase-catalyzed oxidation of sodium linoleate. | 1953 | Arch. Biochem. Biophys. | pmid:13031632 |
| ALVAREZ G | [Effect of linoleic acid (vitamin F?) in therapy of infantile eczema]. | 1952 | Sem Med | pmid:13028610 |
| MONTERO RODRIGUEZ A | [Treatment of constitutional eczema by linoleic acid esters (vitamin F)]. | 1952 Jul-Aug | Rev Esp Pediatr | pmid:13014558 |
| CORTELLA E | [Vitamin F in therapy of psoriasis]. | 1952 | Minerva Dermatol | pmid:12982586 |
| Ogborn MR et al. | Dietary conjugated linoleic acid reduces PGE2 release and interstitial injury in rat polycystic kidney disease. | 2003 | Kidney Int. | pmid:12969139 |
| Corino C et al. | Effect of conjugated linoleic acid on meat quality, lipid metabolism, and sensory characteristics of dry-cured hams from heavy pigs. | 2003 | J. Anim. Sci. | pmid:12968697 |
| Smedman A et al. | Isomer-specific effects of conjugated linoleic acid on lipid peroxidation in humans: regulation by alpha-tocopherol and cyclo-oxygenase-2 inhibitor. | 2004 | Clin. Sci. | pmid:12956622 |
| Shultz TD et al. | Differential stimulatory and inhibitory responses of human MCF-7 breast cancer cells to linoleic acid and conjugated linoleic acid in culture. | 1992 Nov-Dec | Anticancer Res. | pmid:1295460 |
| Seibold SA et al. | Histidine 386 and its role in cyclooxygenase and peroxidase catalysis by prostaglandin-endoperoxide H synthases. | 2003 | J. Biol. Chem. | pmid:12952981 |
| Yang L et al. | Isomeric distribution of conjugated linoleic acids (CLA) in the tissues of layer hens fed a CLA diet. | 2003 | J. Agric. Food Chem. | pmid:12952415 |
| Bull AW et al. | Activation of PPAR gamma in colon tumor cell lines by oxidized metabolites of linoleic acid, endogenous ligands for PPAR gamma. | 2003 | Carcinogenesis | pmid:12949056 |
| Yamamoto K et al. | [Antimutagenic substances in the Armeniacae semen and Persicae semen]. | 1992 | Yakugaku Zasshi | pmid:1294719 |
| Pilitsis JG et al. | Free fatty acids in cerebrospinal fluids from patients with traumatic brain injury. | 2003 | Neurosci. Lett. | pmid:12946571 |
| Sirri F et al. | Fatty acid composition and productive traits of broiler fed diets containing conjugated linoleic acid. | 2003 | Poult. Sci. | pmid:12943310 |
| Kelsey JA et al. | The effect of breed, parity, and stage of lactation on conjugated linoleic acid (CLA) in milk fat from dairy cows. | 2003 | J. Dairy Sci. | pmid:12939083 |
| Dongye G et al. | [The analysis of linseed oil by FTIR and FT-Raman]. | 2000 | Guang Pu Xue Yu Guang Pu Fen Xi | pmid:12938486 |
| Zhao YS et al. | [Changes in fatty acid composition of serum cholesteryl esters in patients with chronic heart failure]. | 2003 | Hunan Yi Ke Da Xue Xue Bao | pmid:12934368 |
| Reissig D et al. | Effect of fatty acids on expression of endothelial leukocyte adhesion molecules. | 2003 | Eur J Nutr | pmid:12923654 |
| Metz TO et al. | Pyridoxamine traps intermediates in lipid peroxidation reactions in vivo: evidence on the role of lipids in chemical modification of protein and development of diabetic complications. | 2003 | J. Biol. Chem. | pmid:12923193 |
| Kim KH and Park HS | Dietary supplementation of conjugated linoleic acid reduces colon tumor incidence in DMH-treated rats by increasing apoptosis with modulation of biomarkers. | 2003 | Nutrition | pmid:12921888 |
| Stockdale CR et al. | Influence of pasture and concentrates in the diet of grazing dairy cows on the fatty acid composition of milk. | 2003 | J. Dairy Res. | pmid:12916820 |
| Hiramoto K et al. | Suppression of free radical-induced DNA strand breaks by linoleic acid and low density lipoprotein in vitro. | 2003 | Biol. Pharm. Bull. | pmid:12913264 |
| Burdge GC et al. | Effect of reduced maternal protein intake in pregnancy in the rat on the fatty acid composition of brain, liver, plasma, heart and lung phospholipids of the offspring after weaning. | 2003 | Br. J. Nutr. | pmid:12908895 |
| Timur S et al. | An enzyme electrode based on lipoxygenase immobilized in gelatin for selective determination of essential fatty acids. | 2003 | Artif Cells Blood Substit Immobil Biotechnol | pmid:12906313 |
| Ye P et al. | The increase in plasminogen activator inhibitor type-1 expression by stimulation of activators for peroxisome proliferator-activated receptors in human endothelial cells. | 2002 | Chin. Med. Sci. J. | pmid:12906165 |
| Mashek DG and Grummer RR | Effects of long chain fatty acids on lipid and glucose metabolism in monolayer cultures of bovine hepatocytes. | 2003 | J. Dairy Sci. | pmid:12906057 |
| Thibault C et al. | Effect of feeding prepubertal heifers with a high oil diet on mammary development and milk production. | 2003 | J. Dairy Sci. | pmid:12906048 |
| Liu Y et al. | Effects of fish oil on lymphocyte proliferation, cytokine production and intracellular signalling in weanling pigs. | 2003 | Arch Tierernahr | pmid:12903861 |
| Miyazawa D et al. | Dietary alpha-linolenic acid suppresses the formation of lysophosphatidic acid, a lipid mediator, in rat platelets compared with linoleic acid. | 2003 | Life Sci. | pmid:12899931 |
| Torres CF et al. | Lipase-catalyzed esterification of conjugated linoleic acid with sorbitol: a kinetic study. | 2003 Jul-Aug | Biotechnol. Prog. | pmid:12892488 |
| Lee SO et al. | Bioconversion of linoleic acid into conjugated linoleic acid during fermentation and by washed cells of Lactobacillus reuteri. | 2003 | Biotechnol. Lett. | pmid:12889826 |
| Kim EJ et al. | Conjugated linoleic acid downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells. | 2003 | J. Nutr. | pmid:12888657 |
| Gollnick H | Current concepts of the pathogenesis of acne: implications for drug treatment. | 2003 | Drugs | pmid:12887264 |
| Lee KW and Lip GY | The role of omega-3 fatty acids in the secondary prevention of cardiovascular disease. | 2003 | QJM | pmid:12881589 |
| Tsevegsuren N et al. | Occurrence of a novel cis,cis,cis-octadeca-3,9,12-trienoic (Z,Z,Z-octadeca-3,9,12-trienoic) acid in Chrysanthemum (tanacetum) zawadskii herb. (Compositae) seed oil. | 2003 | Lipids | pmid:12880115 |
| Cepeljnik T et al. | Is Pseudobutyrivibrio xylanivorans strain Mz5T suitable as a probiotic? An in vitro study. | 2003 | Folia Microbiol. (Praha) | pmid:12879743 |
| Kilian M et al. | Influence of conjugated and conventional linoleic acid on tumor growth and lipid peroxidation in pancreatic adenocarcinoma in hamster. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12878453 |
| Soita HW et al. | Effects of flaxseed supplementation on milk production, milk fatty acid composition and nutrient utilization by lactating dairy cows. | 2003 | Arch Tierernahr | pmid:12866781 |
| Yamasaki M et al. | Alleviation of the cytotoxic activity induced by trans10, cis12-conjugated linoleic acid in rat hepatoma dRLh-84 cells by oleic or palmitoleic acid. | 2003 | Cancer Lett. | pmid:12860277 |
| Griswold KE et al. | Effectiveness of short-term feeding strategies for altering conjugated linoleic acid content of beef. | 2003 | J. Anim. Sci. | pmid:12854825 |
| McNamara S et al. | Effect of offering rumen-protected fat supplements on fertility and performance in spring-calving Holstein-Friesian cows. | 2003 | Anim. Reprod. Sci. | pmid:12853178 |
| Kim YJ | Partial inhibition of biohydrogenation of linoleic acid can increase the conjugated linoleic acid production of Butyrivibrio fibrisolvens A38. | 2003 | J. Agric. Food Chem. | pmid:12848494 |
| Harmon SD et al. | Effect of the delta6-desaturase inhibitor SC-26196 on PUFA metabolism in human cells. | 2003 | Lipids | pmid:12848296 |
| Salvatori G et al. | Control of dietary energy level and dl-alpha-tocopheryl acetate treatment can improve the lipid composition of lamb meat. | 2003 | Int J Vitam Nutr Res | pmid:12847993 |
| Blask DE et al. | Growth and fatty acid metabolism of human breast cancer (MCF-7) xenografts in nude rats: impact of constant light-induced nocturnal melatonin suppression. | 2003 | Breast Cancer Res. Treat. | pmid:12846415 |
| Kamphuis MM et al. | The effect of addition of linoleic acid on food intake regulation in linoleic acid tasters and linoleic acid non-tasters. | 2003 | Br. J. Nutr. | pmid:12844392 |
| Szymczyk B and Pisulewski PM | Effects of dietary conjugated linoleic acid on fatty acid composition and cholesterol content of hen egg yolks. | 2003 | Br. J. Nutr. | pmid:12844380 |
| Nagao T et al. | Purification of conjugated linoleic acid isomers through a process including lipase-catalyzed selective esterification. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12843679 |
| Lima ES et al. | Cholesteryl nitrolinoleate, a nitrated lipid present in human blood plasma and lipoproteins. | 2003 | J. Lipid Res. | pmid:12837858 |
| Alonso L et al. | Production of free conjugated linoleic acid by Lactobacillus acidophilus and Lactobacillus casei of human intestinal origin. | 2003 | J. Dairy Sci. | pmid:12836928 |
| Domergue F et al. | Acyl carriers used as substrates by the desaturases and elongases involved in very long-chain polyunsaturated fatty acids biosynthesis reconstituted in yeast. | 2003 | J. Biol. Chem. | pmid:12835316 |
| Degrace P et al. | Association of liver steatosis with lipid oversecretion and hypotriglyceridaemia in C57BL/6j mice fed trans-10,cis-12-linoleic acid. | 2003 | FEBS Lett. | pmid:12832064 |
| McNeel RL and Mersmann HJ | Effects of isomers of conjugated linoleic acid on porcine adipocyte growth and differentiation. | 2003 | J. Nutr. Biochem. | pmid:12832030 |
| Nagao K et al. | The 10trans, 12cis isomer of conjugated linoleic acid promotes energy metabolism in OLETF rats. | 2003 Jul-Aug | Nutrition | pmid:12831953 |
| Mittendorfer B et al. | What does the measurement of whole-body fatty acid rate of appearance in plasma by using a fatty acid tracer really mean? | 2003 | Diabetes | pmid:12829627 |
| Politis I et al. | Effects of dietary conjugated linoleic acid isomers on several functional properties of macrophages and heterophils in laying hens. | 2003 | Br. Poult. Sci. | pmid:12828205 |
| Sehanputri PS and Hill CG | Lipase-mediated acidolysis of butteroil with free conjugated linoleic acid in a packed bed reactor. | 2003 | Biotechnol. Bioeng. | pmid:12827703 |
| Tamura K et al. | Design and synthesis of 4,6-di-tert-butyl-2,3-dihydro-5-benzofuranols as a novel series of antiatherogenic antioxidants. | 2003 | J. Med. Chem. | pmid:12825946 |
| Giron MD et al. | Long-term effects of dietary monounsaturated and polyunsaturated fatty acids on plasma lipids in dogs. | 1992 Sep-Oct | Arch Int Physiol Biochim Biophys | pmid:1282382 |
| Kamphuis MM et al. | The effect of conjugated linoleic acid supplementation after weight loss on body weight regain, body composition, and resting metabolic rate in overweight subjects. | 2003 | Int. J. Obes. Relat. Metab. Disord. | pmid:12821971 |
| Kim JY and Chung BH | Effects of combination dietary conjugated linoleic acid with vitamin A (retinol) and selenium on the response of the immunoglobulin production in mice. | 2003 | J. Vet. Sci. | pmid:12819373 |
| Hutley LJ et al. | Effects of rosiglitazone and linoleic acid on human preadipocyte differentiation. | 2003 | Eur. J. Clin. Invest. | pmid:12814394 |
| Ristić V and Ristić G | [Role and importance of dietary polyunsaturated fatty acids in the prevention and therapy of atherosclerosis]. | 2003 Jan-Feb | Med. Pregl. | pmid:12793187 |
| Chajes V et al. | Conjugated linoleic acid content in breast adipose tissue of breast cancer patients and the risk of metastasis. | 2003 | Nutr Cancer | pmid:12791500 |
| pmid:12790685 | ||||
| Nagao K et al. | The 10trans,12cis isomer of conjugated linoleic acid suppresses the development of hypertension in Otsuka Long-Evans Tokushima fatty rats. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12788078 |
| Piazza GJ et al. | Isolation of unsaturated diols after oxidation of conjugated linoleic acid with peroxygenase. | 2003 | Lipids | pmid:12784865 |
| Shimada Y et al. | Increased response of liver microsomal delta 6-desaturase activity to dietary methionine in rats. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12784613 |
| Beck S et al. | Potentiation of tumor necrosis factor alpha-induced secreted phospholipase A2 (sPLA2)-IIA expression in mesangial cells by an autocrine loop involving sPLA2 and peroxisome proliferator-activated receptor alpha activation. | 2003 | J. Biol. Chem. | pmid:12782627 |
| Barceló-Coblijn G et al. | Gene expression and molecular composition of phospholipids in rat brain in relation to dietary n-6 to n-3 fatty acid ratio. | 2003 | Biochim. Biophys. Acta | pmid:12782153 |