Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Pitchumoni S et al. | Reoxygenation injury affects isolated islet response to fatty acid stimulation. | 1998 | Metab. Clin. Exp. | pmid:9667226 |
Zock PL and Katan MB | Linoleic acid intake and cancer risk: a review and meta-analysis. | 1998 | Am. J. Clin. Nutr. | pmid:9665108 |
Erickson KL | Is there a relation between dietary linoleic acid and cancer of the breast, colon, or prostate? | 1998 | Am. J. Clin. Nutr. | pmid:9665090 |
Scimeca JA | Toxicological evaluation of dietary conjugated linoleic acid in male Fischer 344 rats. | 1998 | Food Chem. Toxicol. | pmid:9662414 |
Antonova SI | [The dynamics of the secretion of linoleic acid as a component of the lipid classes with milk and their metabolism in the body of cows]. | 1998 Apr-Jun | Usp Fiziol Nauk | pmid:9659686 |
Ohhashi K et al. | Effect of replacing a high linoleate oil with a low linoleate, high alpha-linolenate oil, as compared with supplementing EPA or DHA, on reducing lipid mediator production in rat polymorphonuclear leukocytes. | 1998 | Biol. Pharm. Bull. | pmid:9657037 |
Yazu K et al. | Mechanism of lower oxidizability of eicosapentaenoate than linoleate in aqueous micelles. II. Effect of antioxidants. | 1998 | Lipids | pmid:9655375 |
Bibus DM and Stitt PA | Metabolism of alpha-linolenic acid from flaxseed in dogs. | 1998 | World Rev Nutr Diet | pmid:9648515 |
Kagan VE et al. | Plasma membrane NADH-coenzyme Q0 reductase generates semiquinone radicals and recycles vitamin E homologue in a superoxide-dependent reaction. | 1998 | FEBS Lett. | pmid:9645471 |
Dailly E et al. | Chain-breaking antioxidants and ferriheme-bound drugs are synergistic inhibitors of erythrocyte membrane peroxidation. | 1998 | Free Radic. Res. | pmid:9645396 |