Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Sigmoid Neoplasms D012811 5 associated lipids
Tinea Versicolor D014010 5 associated lipids
Meningeal Neoplasms D008577 5 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Mucositis D052016 7 associated lipids
Nausea D009325 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Anorexia D000855 8 associated lipids
Constipation D003248 8 associated lipids
Otitis Externa D010032 8 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Hypertension, Renal D006977 9 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Protein-Energy Malnutrition D011502 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Song E et al. Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice. 2014 J Am Heart Assoc pmid:24721803
Reed S et al. Dietary zinc deficiency affects blood linoleic acid: dihomo-γ-linolenic acid (LA:DGLA) ratio; a sensitive physiological marker of zinc status in vivo (Gallus gallus). 2014 Nutrients pmid:24658588
Bernhard W et al. Plasma phospholipids indicate impaired fatty acid homeostasis in preterm infants. 2014 Eur J Nutr pmid:24464176
Hodson L et al. Plasma and erythrocyte fatty acids reflect intakes of saturated and n-6 PUFA within a similar time frame. 2014 J. Nutr. pmid:24225449
Farvid MS et al. Dietary linoleic acid and risk of coronary heart disease: a systematic review and meta-analysis of prospective cohort studies. 2014 Circulation pmid:25161045
Harris WS and Shearer GC Omega-6 fatty acids and cardiovascular disease: friend, not foe? 2014 Circulation pmid:25161044
Saito HE et al. Incorporation of exogenous fatty acids protects Enterococcus faecalis from membrane-damaging agents. 2014 Appl. Environ. Microbiol. pmid:25128342
Wu JH et al. Circulating omega-6 polyunsaturated fatty acids and total and cause-specific mortality: the Cardiovascular Health Study. 2014 Circulation pmid:25124495
Phan CW et al. Intrastrain comparison of the chemical composition and antioxidant activity of an edible mushroom, Pleurotus giganteus, and its potent neuritogenic properties. 2014 ScientificWorldJournal pmid:25121118
Purushothaman D et al. Flaxseed oil supplementation alters the expression of inflammatory-related genes in dogs. 2014 Genet. Mol. Res. pmid:25078588
Asselin C et al. Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failure. 2014 Redox Biol pmid:24494189
Mouradian M et al. Key roles for GRB2-associated-binding protein 1, phosphatidylinositol-3-kinase, cyclooxygenase 2, prostaglandin E2 and transforming growth factor alpha in linoleic acid-induced upregulation of lung and breast cancer cell growth. 2014 Prostaglandins Leukot. Essent. Fatty Acids pmid:24374147
Wright CR and Setzer WN Chemical composition of volatiles from Opuntia littoralis, Opuntia ficus-indica, and Opuntia prolifera growing on Catalina Island, California. 2014 Nat. Prod. Res. pmid:24354326
Bakır T et al. Antioxidant/prooxidant effects of α-tocopherol, quercetin and isorhamnetin on linoleic acid peroxidation induced by Cu(II) and H2O2. 2014 Int J Food Sci Nutr pmid:24152374
Huang FC et al. Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola. 2014 Appl. Environ. Microbiol. pmid:24242247
Bonferoni MC et al. Ionic polymeric micelles based on chitosan and fatty acids and intended for wound healing. Comparison of linoleic and oleic acid. 2014 Eur J Pharm Biopharm pmid:24384070
Cho Y et al. Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid docosahexaenoic acid and butyrate through promoter methylation. 2014 Exp. Biol. Med. (Maywood) pmid:24495951
Matthaus B and Özcan MM Fatty acid and tocopherol contents of several soybean oils. 2014 Nat. Prod. Res. pmid:24499198
Dailey MJ et al. Nutrient-specific feeding and endocrine effects of jejunal infusions in obese animals. 2014 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:24452547
Shen J et al. A 13-lipoxygenase, TomloxC, is essential for synthesis of C5 flavour volatiles in tomato. 2014 J. Exp. Bot. pmid:24453226