Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

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Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Sigmoid Neoplasms D012811 5 associated lipids
Tinea Versicolor D014010 5 associated lipids
Meningeal Neoplasms D008577 5 associated lipids
Exocrine Pancreatic Insufficiency D010188 6 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Mucositis D052016 7 associated lipids
Nausea D009325 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Constipation D003248 8 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Otitis Externa D010032 8 associated lipids
Anorexia D000855 8 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Protein-Energy Malnutrition D011502 9 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Palombo JD et al. Metabolism of dietary alpha-linolenic acid vs. eicosapentaenoic acid in rat immune cell phospholipids during endotoxemia. 1998 Lipids pmid:9870905
Kim EJ et al. Development of a serum-free medium for the production of humanized antibody from Chinese hamster ovary cells using a statistical design. 1998 Nov-Dec In Vitro Cell. Dev. Biol. Anim. pmid:9870524
Blaauwwiekel EE et al. Apolipoprotein E genotype is a determinant of low-density lipoprotein cholesterol and of its response to a low-cholesterol diet in Type 1 diabetic patients with elevated urinary albumin excretion. 1998 Diabet. Med. pmid:9868977
Hudson JA et al. Hydration of linoleic acid by bacteria isolated from ruminants. 1998 FEMS Microbiol. Lett. pmid:9868771
Davidson BC et al. The influence of fatty acids on normal and transformed human liver cells in culture. 1998 Sep-Oct Anticancer Res. pmid:9858936
Jarmuszkiewicz W et al. Linoleic acid-induced activity of plant uncoupling mitochondrial protein in purified tomato fruit mitochondria during resting, phosphorylating, and progressively uncoupled respiration. 1998 J. Biol. Chem. pmid:9857016
Spiteller G Linoleic acid peroxidation--the dominant lipid peroxidation process in low density lipoprotein--and its relationship to chronic diseases. 1998 Chem. Phys. Lipids pmid:9853364
Wagner K et al. Research note: effect of duodenal--infused unsaturated fatty acids on dairy milk composition. 1998 Arch Tierernahr pmid:9850802
Louw L et al. Comparison of the fatty acid compositions in intraepithelial and infiltrating lesions of the cervix: part I, total fatty acid profiles. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9849650
Chobot'ko HM [Effects of modifications of lipoproteins by water soluble forms of lineoleic-hydroxamic acid on biochemical markers of development of atherosclerosis]. 1998 Jul-Aug Ukr. Biokhim. Zh. pmid:9848203
Nestel PJ et al. Effect of a stearic acid-rich, structured triacylglycerol on plasma lipid concentrations. 1998 Am. J. Clin. Nutr. pmid:9846846
Oyama Y et al. Protective actions of 5'-n-alkylated curcumins on living cells suffering from oxidative stress. 1998 Eur. J. Pharmacol. pmid:9845274
Turpeinen AM et al. A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9844997
Phifer CB and Berthoud HR Duodenal nutrient infusions differentially affect sham feeding and Fos expression in rat brain stem. 1998 Am. J. Physiol. pmid:9841547
Iwase H et al. Calcium is required for quasi-lipoxygenase activity of hemoproteins. 1998 Free Radic. Biol. Med. pmid:9840740
Gu JY et al. Effect of dietary fats and sesamin on the lipid metabolism and immune function of Sprague-Dawley rats. 1998 Biosci. Biotechnol. Biochem. pmid:9836427
Sehat N et al. Identification of conjugated linoleic acid isomers in cheese by gas chromatography, silver ion high performance liquid chromatography and mass spectral reconstructed ion profiles. Comparison of chromatographic elution sequences. 1998 Lipids pmid:9832075
Morita Y et al. Involvement of lipid peroxidation in free fatty acid-induced isolated rat pancreatic acinar cell injury. 1998 Pancreas pmid:9821180
Fukuda N et al. Effect of emeriamine, an inhibitor of fatty acid oxidation, on metabolic fate of a geometrical isomer of linoleic acid in perfused rat liver. 1998 J. Nutr. Sci. Vitaminol. pmid:9819713
Broun P et al. Catalytic plasticity of fatty acid modification enzymes underlying chemical diversity of plant lipids. 1998 Science pmid:9812895