Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Negrini R et al. | Influence of electrostatic interactions on the release of charged molecules from lipid cubic phases. | 2014 | Langmuir | pmid:24673189 |
Garrel G et al. | Unsaturated fatty acids disrupt Smad signaling in gonadotrope cells leading to inhibition of FSHβ gene expression. | 2014 | Endocrinology | pmid:24248462 |
Kim JY et al. | Role of moisture on the lipid oxidation determined by D(2)O in a linoleic acid model system. | 2014 | Food Chem | pmid:24176324 |
Sponton OE et al. | Effect of limited enzymatic hydrolysis on linoleic acid binding properties of β-lactoglobulin. | 2014 | Food Chem | pmid:24176383 |
Kwon B et al. | Oleate prevents palmitate-induced mitochondrial dysfunction, insulin resistance and inflammatory signaling in neuronal cells. | 2014 | Biochim. Biophys. Acta | pmid:24732014 |
Breiden B and Sandhoff K | The role of sphingolipid metabolism in cutaneous permeability barrier formation. | 2014 | Biochim. Biophys. Acta | pmid:23954553 |