Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Precancerous Conditions D011230 48 associated lipids
Fatty Liver D005234 48 associated lipids
Psoriasis D011565 47 associated lipids
Starvation D013217 47 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Heart Failure D006333 36 associated lipids
Acne Vulgaris D000152 35 associated lipids
Glomerulonephritis D005921 35 associated lipids
Hyperplasia D006965 34 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Liver Diseases D008107 31 associated lipids
Dermatitis D003872 30 associated lipids
Proteinuria D011507 30 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Geer BW et al. The effect of dietary ethanol on the composition of lipids of Drosophila melanogaster larvae. 1986 Biochem. Genet. pmid:2938574
Boberg M et al. High content of dietary linoleic acid does not reduce platelet reactivity in patients with hyperlipoproteinaemia. 1986 Eur. J. Clin. Invest. pmid:2938965
Orchard S et al. Poison ivy/oak dermatitis. Use of polyamine salts of a linoleic acid dimer for topical prophylaxis. 1986 Arch Dermatol pmid:2942115
May V and Eipper BA Long term culture of primary rat pituitary adrenocorticotropin/endorphin-producing cells in serum-free medium. 1986 Endocrinology pmid:3004908
Kühn H et al. The stoichiometry of oxygen uptake and conjugated diene formation during the dioxygenation of linoleic acid by the pure reticulocyte lipoxygenase. Evidence for aerobic hydroperoxidase activity. 1986 Biochim. Biophys. Acta pmid:3006782
Murphy MG Studies of the regulation of basal adenylate cyclase activity by membrane polyunsaturated fatty acids in cultured neuroblastoma. 1986 J. Neurochem. pmid:3011993
Skogh M Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids) 1986 J. Am. Acad. Dermatol. pmid:3013957
Kher V et al. Protective effect of polyunsaturated fatty acid supplementation in apoferritin induced murine glomerulonephritis. 1986 Prostaglandins Leukot Med pmid:3014561
Connor HD et al. A search for oxygen-centered free radicals in the lipoxygenase/linoleic acid system. 1986 Biochem. Biophys. Res. Commun. pmid:3026385
Stymne S and Stobart AK Biosynthesis of gamma-linolenic acid in cotyledons and microsomal preparations of the developing seeds of common borage (Borago officinalis). 1986 Biochem. J. pmid:3028375
van Staveren WA et al. Validity of the fatty acid composition of subcutaneous fat tissue microbiopsies as an estimate of the long-term average fatty acid composition of the diet of separate individuals. 1986 Am. J. Epidemiol. pmid:3946391
Nijssen JG and van den Bosch H Cytosol-stimulated remodeling of phosphatidylcholine in rat lung microsomes. 1986 Biochim. Biophys. Acta pmid:3947653
Kryvi H et al. Effects of essential fatty acid deficiency on mitochondria and peroxisomes in rat hepatocytes with special reference to a partially hydrogenated fish oil diet. 1986 Biochim. Biophys. Acta pmid:3947675
De Villiers M and Lochner A Mitochondrial Ca2+ fluxes: role of free fatty acids, acyl-CoA and acylcarnitine. 1986 Biochim. Biophys. Acta pmid:3955069
Fressinaud C et al. Fatty acid composition of endoneurium and perineurium from adult rat sciatic nerve. 1986 J. Neurochem. pmid:3958717
Becker W and Bruce A Retention of linoleic acid in carcass lipids of rats fed different levels of essential fatty acids. 1986 Lipids pmid:3959773
Otsuki T et al. Two geometrical isomers of linoleic acid: improved total syntheses. 1986 Lipids pmid:3959777
Kanofsky JR and Axelrod B Singlet oxygen production by soybean lipoxygenase isozymes. 1986 J. Biol. Chem. pmid:3080416
Renner F et al. Effect of saturated and unsaturated lipid on the composition of mesenteric triglyceride-rich lipoproteins in the rat. 1986 J. Lipid Res. pmid:3083032
Innis SM Effect of total parenteral nutrition with linoleic acid-rich emulsions on tissue omega 6 and omega 3 fatty acids in the rat. 1986 Lipids pmid:3083173
Kanazawa K et al. The effect of orally administered secondary autoxidation products of linoleic acid on the activity of detoxifying enzymes in the rat liver. 1986 Biochim. Biophys. Acta pmid:3768385
Effect of age on the linoleate content of skin acylglucosylceramide in mice. 1986 Nutr. Rev. pmid:3796906
Utermohlen V and Tucker MA Possible effects of dietary n-6 series polyunsaturated fatty acids on the development of immune dysfunction and infection. 1986 Proc Nutr Soc pmid:3797410
Lehmann J et al. Vitamin E in foods from high and low linoleic acid diets. 1986 J Am Diet Assoc pmid:3745745
Fusco AC et al. Schistosoma mansoni: production of cercarial eicosanoids as correlates of penetration and transformation. 1986 J. Parasitol. pmid:3746561
Takase S and Hosoya N Effect of dietary medium chain triglyceride on lipogenic enzyme activity in rat liver. 1986 J. Nutr. Sci. Vitaminol. pmid:3761045
Takagi M et al. Effects of lipophilic derivatives of L-ascorbic acid and dehydro-L-ascorbic acid on the peroxidation of linoleic acid in neutral phosphate buffer containing alcohol. 1986 J. Nutr. Sci. Vitaminol. pmid:3806253
Masuda Y et al. The mode of enhanced enteral absorption of macromolecules by lipid-surfactant mixed micelles. I. 1986 J. Pharmacobio-dyn. pmid:3820056
Wertz PW and Downing DT Linoleate content of epidermal acylglucosylceramide in newborn, growing and mature mice. 1986 Biochim. Biophys. Acta pmid:3707979
Vericel E et al. Effects of linoleic acid and gamma-linolenic acid intake on platelet functions in elderly people. 1986 Thromb. Res. pmid:3715813
Hajarine M and Lagarde M Studies on polyenoic acid incorporation into human platelet lipid stores: interactions with linoleic and arachidonic acids. 1986 Biochim. Biophys. Acta pmid:3719006
Dowd TC et al. Diabetic retinopathy: different risk factors for exudates and haemorrhages. 1986 Int Ophthalmol pmid:3721707
Awad AB and Chattopadhyay JP Effect of dietary saturated fatty acids on intracellular free fatty acids and kinetic properties of hormone-sensitive lipase of rat adipocytes. 1986 J. Nutr. pmid:3723204
Leikin AI and Brenner RR Regulation of linoleic acid delta 6-desaturation by a cytosolic lipoprotein-like fraction in isolated rat liver microsomes. 1986 Biochim. Biophys. Acta pmid:2869785
Isaacs CE et al. Membrane-disruptive effect of human milk: inactivation of enveloped viruses. 1986 J. Infect. Dis. pmid:3491166
Wolfram G et al. Pain, prostaglandins, and food lipids. Influences of dietary polyunsaturated fatty acids on eicosanoid synthesis and effects. 1986 Bibl Nutr Dieta pmid:2870709
Carlson SE et al. High fat diets varying in ratios of polyunsaturated to saturated fatty acid and linoleic to linolenic acid: a comparison of rat neural and red cell membrane phospholipids. 1986 J. Nutr. pmid:2871142
Rocquelin G et al. [Influence of linoleic acid (18:2 n-6) and alpha-linolenic acid (18:3 n-3) on the composition, permeability and fluidity of cardiac phospholipids in the rat: study using membrane models (liposomes)]. 1986 Reprod Nutr Dev pmid:2871601
Gabor H and Abraham S Effect of dietary menhaden oil on tumor cell loss and the accumulation of mass of a transplantable mammary adenocarcinoma in BALB/c mice. 1986 J. Natl. Cancer Inst. pmid:3458958
Köhler VH et al. [Results of a long-term study of arteriosclerotic circulatory disorders with polyene fatty acid therapy]. 1986 Z Gesamte Inn Med pmid:2871668
Elliott GR et al. Linoleic and dihomo-gamma-linolenic acids modulate granuloma growth and granuloma macrophage eicosanoid release. 1986 Eur. J. Pharmacol. pmid:3460810
Leat WM et al. Retinal function in rats and guinea-pigs reared on diets low in essential fatty acids and supplemented with linoleic or linolenic acids. 1986 Ann. Nutr. Metab. pmid:2872851
Jenkins KJ and Kramer JK Influence of low linoleic and linolenic acids in milk replacer on calf performance and lipids in blood plasma, heart, and liver. 1986 J. Dairy Sci. pmid:2873158
Siguel EN et al. Monitoring the optimal infusion of intravenous lipids. Detection of essential fatty acid deficiency. 1986 Arch. Pathol. Lab. Med. pmid:2875703
Morson LA and Clandinin MT Diets varying in linoleic and linolenic acid content alter liver plasma membrane lipid composition and glucagon-stimulated adenylate cyclase activity. 1986 J. Nutr. pmid:2879899
Izumi Y et al. Effects of dietary linoleic acid on blood pressure and renal function in subtotally nephrectomized rats. 1986 Proc. Soc. Exp. Biol. Med. pmid:3532127
Hoffmann P et al. Cardiovascular actions of dihydralazine as modified by dietary linoleic acid. 1986 Biomed. Biochim. Acta pmid:3535786
Hoffmann P et al. Circadian rhythm of eicosanoid formation as affected by dietary linoleate. 1986 Prostaglandins Leukot Med pmid:3547416
Iriyama K et al. Metabolism of non-protein energy-substrates in septic rats receiving parenteral nutrition. 1986 Jan-Mar Int Surg pmid:3087901
Koletzko B et al. Comparison of fatty acid composition of plasma lipid fractions in well-nourished Nigerian and German infants and toddlers. 1986 Jul-Aug J. Pediatr. Gastroenterol. Nutr. pmid:3090220
Kaunitz H Medium chain triglycerides (MCT) in aging and arteriosclerosis. 1986 Mar-Apr J. Environ. Pathol. Toxicol. Oncol. pmid:3519928
Kummerow FA Dietary effects of trans fatty acids. 1986 Mar-Apr J. Environ. Pathol. Toxicol. Oncol. pmid:3519929
Fukuzumi K Relationship between lipoperoxides and diseases. 1986 Mar-Apr J. Environ. Pathol. Toxicol. Oncol. pmid:3519933
Olivi O et al. [A new and original therapy for seborrheic dermatitis]. 1986 May-Jun Pediatr Med Chir pmid:2947051
Lester LA et al. Supplemental parenteral nutrition in cystic fibrosis. 1986 May-Jun JPEN J Parenter Enteral Nutr pmid:3086588
Young MR et al. Stimulation of hematopoiesis and bone marrow suppressor cells by the subcutaneous injection of linoleic acid. 1987 Cell. Immunol. pmid:2953447
Ringertz B et al. High dietary linoleic acid content modulates neutrophil function in rats. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960199
Salonen R et al. Effect of omega-3 fatty acid supplementation on platelet aggregability and platelet produced thromboxane. 1987 Thromb. Haemost. pmid:3660329
Dupont J Essential fatty acids and prostaglandins. 1987 Prev Med pmid:3628199
Steinberg WM et al. Cerulein induces hyperplasia of the pancreas in a rat model of chronic pancreatic insufficiency. 1987 Pancreas pmid:3628223
Kromhout D et al. Long-term effects of a linoleic acid-enriched diet, changes in body weight and alcohol consumption on serum total and HDL-cholesterol. 1987 Atherosclerosis pmid:3632757
Berlin E et al. Dietary linoleate increases fluidity and influences chemical composition of plasma low density lipoprotein in adult men. 1987 Atherosclerosis pmid:3632760
Field EJ and Joyce G Duchenne muscular dystrophy: do both parents contribute genetically to the disease? 1987 J. Neurol. Sci. pmid:3126270
Funk CD et al. Effects of selenium-deficient diets on the production of prostaglandins and other oxygenated metabolites of arachidonic acid and linoleic acid by rat and rabbit aortae. 1987 Biochim. Biophys. Acta pmid:3115301
Walstra P et al. Demonstration of a 12-lipoxygenase activity in bovine polymorphonuclear leukocytes. 1987 Biochim. Biophys. Acta pmid:3115302
Colard O et al. Hydrolysis of endogenous phospholipids by rat platelet phospholipase A2: ether or acyl bond and polar head group selectivity. 1987 Biochim. Biophys. Acta pmid:3115303
Murphy MG et al. Effects of membrane polyunsaturated fatty acids on opiate peptide inhibition of basal and prostaglandin E1-stimulated cyclic AMP formation in intact N1E-115 neuroblastoma cells. 1987 Biochem. Pharmacol. pmid:2825714
Wehrmann W et al. [Clinical and immune-modulating effects of the treatment with unsaturated fatty acids in atopic dermatitis]. 1987 Z. Hautkr. pmid:2831674
Cunnane SC and McAdoo KR Iron intake influences essential fatty acid and lipid composition of rat plasma and erythrocytes. 1987 J. Nutr. pmid:3116180
Salafsky B and Fusco AC Schistosoma mansoni: a comparison of secreted vs nonsecreted eicosanoids in developing schistosomulae and adults. 1987 Exp. Parasitol. pmid:2824233
Uotila P et al. Relaxing effects of 15-lipoxygenase products of arachidonic acid on rat aorta. 1987 J. Pharmacol. Exp. Ther. pmid:3116200
Bomalaski JS et al. Alteration of uptake and distribution of eicosanoid precursor fatty acids by aspirin. 1987 Biochem. Pharmacol. pmid:3117063
McLennan PL et al. Dietary lipid modulation of myocardial beta-adrenergic mechanisms, Ca2+-dependent automaticity, and arrhythmogenesis in the marmoset. 1987 J. Cardiovasc. Pharmacol. pmid:2444777
Popp-Snijders C et al. Dietary supplementation of omega-3 polyunsaturated fatty acids improves insulin sensitivity in non-insulin-dependent diabetes. 1987 Diabetes Res. pmid:3038454
Kaneko T et al. Lethal effects of a linoleic acid hydroperoxide and its autoxidation products, unsaturated aliphatic aldehydes, on human diploid fibroblasts. 1987 Chem. Biol. Interact. pmid:3664790
Das UN et al. Uptake and distribution of cis-unsaturated fatty acids and their effect on free radical generation in normal and tumor cells in vitro. 1987 Free Radic. Biol. Med. pmid:3040539
Fisher M et al. Linoleic acid levels in white blood cells, platelets, and serum of multiple sclerosis patients. 1987 Acta Neurol. Scand. pmid:3687373
Ashida H et al. Effect of orally administered secondary autoxidation products of linoleic acid on carbohydrate metabolism in rat liver. 1987 Arch. Biochem. Biophys. pmid:3688880
Willett WC et al. Dietary fat and the risk of breast cancer. 1987 N. Engl. J. Med. pmid:3785347
Jensen E et al. Cell-density-dependent uptake of chylomicron remnants in rat hepatocyte monolayers. Effects of compactin and mevalonic acid. 1987 Biochim. Biophys. Acta pmid:3790613
del Nido PJ et al. Evidence of myocardial free radical injury during elective repair of tetralogy of Fallot. 1987 Circulation pmid:2959398
Mackie BS et al. Melanoma and dietary lipids. 1987 Nutr Cancer pmid:3110746
Castańeda-Hernández G Presence of endogenous digitalis-like activity in mammalian heart not due to fatty acids. 1987 Biochem. Pharmacol. pmid:3036154
Ito Y et al. A low protein-high linoleate diet increases glomerular PGE2 and protects renal function in rats with reduced renal mass. 1987 Prostaglandins Leukot Med pmid:3477824
Yamamoto N et al. Effect of dietary alpha-linolenate/linoleate balance on brain lipid compositions and learning ability of rats. 1987 J. Lipid Res. pmid:2883248
Kramer HJ et al. The role of renal prostaglandins in the regulation of renal sodium excretion. 1987 Agents Actions Suppl. pmid:3481214
Croft KD et al. Differential inhibition of thromboxane B2 and leukotriene B4 biosynthesis by two naturally occurring acetylenic fatty acids. 1987 Biochim. Biophys. Acta pmid:2822134
Tischinger-Wagner H et al. [Oxidative degradation of linoleic acid methyl ester in suspensions of inorganic excipients. 1. Auto-oxidation in the presence of silicic acid products and aluminum oxide]. 1987 Pharmazie pmid:2823296
Gyllenhammar H et al. Dietary essential fatty acid deficiency in rats is accompanied by impairments in neutrophil function and leukotriene B4 generation. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2823572
Clementz T et al. Membrane potential, lipid regulation and adenylate energy charge in acyl chain modified Acholeplasma laidlawii. 1987 Biochim. Biophys. Acta pmid:3567184
Strannegård IL et al. Essential fatty acids in serum lecithin of children with atopic dermatitis and in umbilical cord serum of infants with high or low IgE levels. 1987 Int. Arch. Allergy Appl. Immunol. pmid:3570505
Heifets M et al. Effect of dietary lipids on renal function in rats with subtotal nephrectomy. 1987 Kidney Int. pmid:3669493
Takahashi R et al. Impaired platelet aggregation and thromboxane generation in essential fatty acid-deficient rats. 1987 J. Nutr. pmid:2888839
Coté GG and Brody S Circadian rhythms in Neurospora crassa: a clock mutant, prd-1, is altered in membrane fatty acid composition. 1987 Biochim. Biophys. Acta pmid:2889471
Hubbard NE and Erickson KL Enhancement of metastasis from a transplantable mouse mammary tumor by dietary linoleic acid. 1987 Cancer Res. pmid:3677068
Thoresen L and Bjerve KS [From clinical nursing: long-term tube feeding can cause deficiency diseases]. 1987 Sykepleien pmid:2891206
Sanders TA and Rana SK Comparison of the metabolism of linoleic and linolenic acids in the fetal rat. 1987 Ann. Nutr. Metab. pmid:2892461
Betteridge J Nutrition and platelet function in atherogenesis. 1987 Proc Nutr Soc pmid:2893383
Loesberg C et al. Effects of dietary poly-unsaturated fatty acids on tracheal histaminergic and cholinergic responsiveness in experimental models of bronchial hypersensitivity and hyperreactivity. 1987 Agents Actions pmid:2895570
Nugteren DH and Kivits GA Conversion of linoleic acid and arachidonic acid by skin epidermal lipoxygenases. 1987 Biochim. Biophys. Acta pmid:3113487