| MeSH term | MeSH ID | Detail |
|---|---|---|
| Alopecia | D000505 | 14 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Aneurysm | D000783 | 2 associated lipids |
| Acidosis | D000138 | 13 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Hypertension, Pulmonary | D006976 | 32 associated lipids |
| Proteinuria | D011507 | 30 associated lipids |
| Refsum Disease | D012035 | 19 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Hyperplasia | D006965 | 34 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Brodersen R et al. | Multiple fatty acid binding to albumin in human blood plasma. | 1990 | Eur. J. Biochem. | pmid:2338079 |
| Sams GH et al. | Isolation and characterization of a fatty acid binding protein in adipose tissue of Gallus domesticus. | 1990 | Comp. Biochem. Physiol., B | pmid:1697230 |
| Girón MD et al. | Changes in lipid composition and desaturase activities of duodenal mucosa induced by dietary fat. | 1990 | Biochim. Biophys. Acta | pmid:2369586 |
| Barros H et al. | Arachidonic acid absorption in human jejunum in organ culture: effects of ethanol. | 1990 | Eur. J. Clin. Invest. | pmid:2124981 |
| Teter BB et al. | Milk fat depression in C57Bl/6J mice consuming partially hydrogenated fat. | 1990 | J. Nutr. | pmid:2380791 |
| DeLange RJ and Glazer AN | Bile acids: antioxidants or enhancers of peroxidation depending on lipid concentration. | 1990 | Arch. Biochem. Biophys. | pmid:2297222 |
| Ha YL et al. | Inhibition of benzo(a)pyrene-induced mouse forestomach neoplasia by conjugated dienoic derivatives of linoleic acid. | 1990 | Cancer Res. | pmid:2297758 |
| Kawahara J et al. | Dietary linoleic acid prevents the development of deoxycorticosterone acetate-salt hypertension. | 1990 | Hypertension | pmid:2298478 |
| Parinandi NL et al. | Diabetic heart and kidney exhibit increased resistance to lipid peroxidation. | 1990 | Biochim. Biophys. Acta | pmid:2123402 |
| Lefkowith J et al. | Prevention of diabetes in the BB rat by essential fatty acid deficiency. Relationship between physiological and biochemical changes. | 1990 | J. Exp. Med. | pmid:2307932 |
| Buckman DK et al. | Modulation of mouse mammary tumor growth and linoleate enhanced metastasis by oleate. | 1990 | J. Nutr. | pmid:2313378 |
| MacIver DH et al. | The effect of short chain fatty acid supplementation on membrane electrolyte transport and blood pressure. | 1990 | J Hum Hypertens | pmid:2283638 |
| Jakobsson A et al. | Metabolism of fatty acids and their incorporation into phospholipids of the mitochondria and endoplasmic reticulum in isolated hepatocytes determined by isolation of fluorescence derivatives. | 1990 | Biochim. Biophys. Acta | pmid:2223867 |
| Buset M et al. | Injury induced by fatty acids or bile acid in isolated human colonocytes prevented by calcium. | 1990 | Cancer Lett. | pmid:2322935 |
| Katzenellenbogen BS and Norman MJ | Multihormonal regulation of the progesterone receptor in MCF-7 human breast cancer cells: interrelationships among insulin/insulin-like growth factor-I, serum, and estrogen. | 1990 | Endocrinology | pmid:2404751 |
| Jensen MD et al. | Measurement of non-steady-state free fatty acid turnover. | 1990 | Am. J. Physiol. | pmid:2405695 |
| Miller CC and Ziboh VA | Induction of epidermal hyperproliferation by topical n-3 polyunsaturated fatty acids on guinea pig skin linked to decreased levels of 13-hydroxyoctadecadienoic acid (13-hode). | 1990 | J. Invest. Dermatol. | pmid:2106562 |
| Okuyama H | [Does food affect brain functions?]. | 1990 | Tanpakushitsu Kakusan Koso | pmid:1970438 |
| elAttar TM et al. | Comparison of the inhibitory effect of polyunsaturated fatty acids on prostaglandin synthesis. II. Fibroblasts. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1971442 |
| Kestin M et al. | n-3 fatty acids of marine origin lower systolic blood pressure and triglycerides but raise LDL cholesterol compared with n-3 and n-6 fatty acids from plants. | 1990 | Am. J. Clin. Nutr. | pmid:1971991 |
| Watanabe S et al. | Effect of dietary alpha-linolenate/linoleate balance on crescent type-anti-glomerular basement membrane nephritis in rats. | 1990 | Lipids | pmid:1972260 |
| Singer P et al. | Effects of dietary oleic, linoleic and alpha-linolenic acids on blood pressure, serum lipids, lipoproteins and the formation of eicosanoid precursors in patients with mild essential hypertension. | 1990 | J Hum Hypertens | pmid:1972963 |
| Lipids and multiple sclerosis. | 1990 | Lancet | pmid:1973215 | |
| Oxholm A et al. | Abnormal essential fatty acid metabolism in Darier's disease. | 1990 | Arch Dermatol | pmid:1977367 |
| Lester DS | In vitro linoleic acid activation of protein kinase C. | 1990 | Biochim. Biophys. Acta | pmid:2207179 |
| Høy CE and Hølmer G | Influence of dietary linoleic acid and trans fatty acids on the fatty acid profile of cardiolipins in rats. | 1990 | Lipids | pmid:2215088 |
| Buko VU | Beef fat prevents alcoholic liver disease in the rat. | 1990 | Alcohol. Clin. Exp. Res. | pmid:2221295 |
| Opara EC et al. | Enhancement of endocrine pancreatic secretions by essential fatty acids. | 1990 | J. Surg. Res. | pmid:2187112 |
| Dupont J and Dowd MK | Icosanoid synthesis as a functional measurement of essential fatty acid requirement. | 1990 | J Am Coll Nutr | pmid:2193052 |
| Kitagawa S et al. | Inhibitory mechanism of cis-polyunsaturated fatty acids on platelet aggregation: the relation with their effects on Ca2+ mobilization, cyclic AMP levels and membrane fluidity. | 1990 | Biochim. Biophys. Acta | pmid:2166588 |
| Kulkarni AP et al. | Hydrogen peroxide: a potent activator of dioxygenase activity of soybean lipoxygenase. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2105721 |
| Umeda F et al. | Modification of prostacyclin-stimulatory activity in sera by glucose, insulin, low density lipoprotein, linoleic acid and linoleic acid hydroperoxide. | 1990 | Diabetes Res. Clin. Pract. | pmid:2106424 |
| Lasekan JB et al. | Dietary olive and safflower oils in promotion of DMBA-induced mammary tumorigenesis in rats. | 1990 | Nutr Cancer | pmid:2106675 |
| Tonogai Y and Tai HH | Quantitation of 13-hydroxyoctadecadienoic acid (13-HODE) by radioimmunoassay. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2111553 |
| Green P et al. | Effects of fish-oil ingestion on cardiovascular risk factors in hyperlipidemic subjects in Israel: a randomized, double-blind crossover study. | 1990 | Am. J. Clin. Nutr. | pmid:2239789 |
| Fletcher JE et al. | Fatty acid uptake and catecholamine-stimulated phospholipid metabolism in immortalized airway epithelial cells established from primary cultures. | 1990 | Biochem. Int. | pmid:2241999 |
| Mimouni V and Poisson JP | Spontaneous diabetes in BB rats: evidence for insulin dependent liver microsomal delta 6 and delta 5 desaturase activities. | 1990 | Horm. Metab. Res. | pmid:2227799 |
| Pariza MW and Ha YL | Conjugated dienoic derivatives of linoleic acid: a new class of anticarcinogens. | 1990 | Med Oncol Tumor Pharmacother | pmid:2232933 |
| Moore SA et al. | Role of the blood-brain barrier in the formation of long-chain omega-3 and omega-6 fatty acids from essential fatty acid precursors. | 1990 | J. Neurochem. | pmid:2115069 |
| Nikolaev V et al. | Stereochemical nature of the products of linoleic acid oxidation catalyzed by lipoxygenases from potato and soybean. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2116790 |
| Mensink RP et al. | Effect of a monounsaturated diet vs. a polyunsaturated fatty acid-enriched diet on blood pressure in normotensive women and men. | 1990 | Eur. J. Clin. Invest. | pmid:2121507 |
| Newman MJ | Inhibition of carcinoma and melanoma cell growth by type 1 transforming growth factor beta is dependent on the presence of polyunsaturated fatty acids. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2371287 |
| Chatterjee S and Ghosh N | Phosphatidylcholine stimulates the activity of UDP-Gal beta 1-4 galactosyltransferase in normal human kidney proximal tumour cells. | 1990 | Indian J. Biochem. Biophys. | pmid:2129343 |
| Koba K and Sugano M | Dietary protein influences polyunsaturated fatty acid patterns of rat tissue lipids. | 1990 | J. Nutr. Sci. Vitaminol. | pmid:2130152 |
| Yashiro K et al. | [Changes in the free fatty acid composition of rat salivary glands induced by chronic administration of isoproterenol]. | 1990 | Gifu Shika Gakkai Zasshi | pmid:2133668 |
| Masini E et al. | Histamine release from rat mast cells induced by metabolic activation of polyunsaturated fatty acids into free radicals. | 1990 | Biochem. Pharmacol. | pmid:1690007 |
| Field CJ et al. | Diet fat composition alters membrane phospholipid composition, insulin binding, and glucose metabolism in adipocytes from control and diabetic animals. | 1990 | J. Biol. Chem. | pmid:2113530 |
| Kim D and Duff RA | Regulation of K+ channels in cardiac myocytes by free fatty acids. | 1990 | Circ. Res. | pmid:2119911 |
| Molina MT et al. | Caecal and colonic uptake of both linoleic acid and cholesterol in rats following intestinal resection. | 1990 | Lipids | pmid:2079865 |
| Corner EJ et al. | Accumulation of eicosapentaenoic acid in plasma phospholipids of subjects fed canola oil. | 1990 | Lipids | pmid:2079866 |
| Henricks PA et al. | Epithelium-derived linoleic acid metabolites modulate airway smooth muscle function. | 1990 | Agents Actions Suppl. | pmid:2080762 |
| Emken EA et al. | Metabolism in vivo of deuterium-labelled linolenic and linoleic acids in humans. | 1990 | Biochem. Soc. Trans. | pmid:2083671 |
| James SR et al. | Linoleic acid increases cytosolic Ca2+ in lymphocytes. | 1990 | Biochem. Soc. Trans. | pmid:2083720 |
| Zakhariv OIa et al. | [Metabolism of linoleic acid given with the feed in the calf liver]. | 1990 Jan-Feb | Ukr. Biokhim. Zh. | pmid:2336726 |
| Shultz TD | Physiological free fatty acid concentrations do not increase free estradiol in plasma. | 1991 | J. Clin. Endocrinol. Metab. | pmid:1986028 |
| Hrboticky N et al. | Retina fatty acid composition of piglets fed from birth with a linoleic acid-rich vegetable-oil formula for infants. | 1991 | Am. J. Clin. Nutr. | pmid:1989416 |
| Kearns EV et al. | The role of cytochrome b5 in delta 12 desaturation of oleic acid by microsomes of safflower (Carthamus tinctorius L.). | 1991 | Arch. Biochem. Biophys. | pmid:1989527 |
| Hou SY et al. | Membrane structures in normal and essential fatty acid-deficient stratum corneum: characterization by ruthenium tetroxide staining and x-ray diffraction. | 1991 | J. Invest. Dermatol. | pmid:1991982 |
| Muakkassa FF et al. | Effect of dietary fish oil on plasma thromboxane B2 and 6-keto-prostaglandin F1 alpha levels in septic rats. | 1991 | Arch Surg | pmid:1992995 |
| Hendrich S et al. | Phenobarbital increases rat hepatic prostaglandin F2 alpha, glutathione S-transferase activity and oxidative stress. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2011611 |
| Fusco AC et al. | Schistosoma mansoni: the role of calcium in the stimulation of cercarial proteinase release. | 1991 | J. Parasitol. | pmid:1717671 |
| Zirvi KA | Development of serum-free media for the growth of human gastrointestinal adenocarcinoma xenografts as primary tissue cultures. | 1991 | J. Cancer Res. Clin. Oncol. | pmid:1720783 |
| Fukuzawa K et al. | Peroxide-dependent and -independent lipid peroxidations catalyzed by chelated iron. | 1991 | Arch. Biochem. Biophys. | pmid:1656881 |
| Iversen L et al. | Linoleic acid and dihomogammalinolenic acid inhibit leukotriene B4 formation and stimulate the formation of their 15-lipoxygenase products by human neutrophils in vitro. Evidence of formation of antiinflammatory compounds. | 1991 | Agents Actions | pmid:1659156 |
| Pettersen J and Opstvedt J | Trans fatty acids. 4. Effects on fatty acid composition of colostrum and milk. | 1991 | Lipids | pmid:1762516 |
| Gyllenhammar H et al. | Effects of an essential fatty acid-supplemented diet on leukotriene B4-induced rat neutrophil functions. | 1991 | Scand. J. Clin. Lab. Invest. | pmid:1662827 |
| Butovich IA et al. | The unusual action of (R,S)-2-hydroxy-2-trifluoromethyl-trans-n-octadec-4-enoic acid on 5-lipoxygenase from potato tubers. | 1991 | Eur. J. Biochem. | pmid:2065670 |
| Rose DP and Connolly JM | Effects of fatty acids and eicosanoid synthesis inhibitors on the growth of two human prostate cancer cell lines. | 1991 | Prostate | pmid:2020620 |
| Bull AW et al. | Metabolism of oxidized linoleic acid: distribution of activity for the enzymatic oxidation of 13-hydroxyoctadecadienoic acid to 13-oxooctadecadienoic acid in rat tissues. | 1991 | Prostaglandins | pmid:2020745 |
| Schreiner GF | Dietary treatment of immunologically mediated renal disease. | 1991 | Kidney Int. Suppl. | pmid:2046271 |
| Venkatraman JT et al. | Influence of genotype on diet-induced changes in membrane phosphatidylcholine and phosphatidylethanolamine composition of splenocytes, liver nuclear envelope and liver mitochondria. | 1991 | Lipids | pmid:2046486 |
| Rubinstein A et al. | Fatty acid composition of adipose tissue in Ethiopian immigrants: a prospective study during their first year in Israel. | 1991 | Isr. J. Med. Sci. | pmid:2050506 |
| Holman RT | Highpoints in an affair with polyunsaturated fatty acids. | 1991 | World Rev Nutr Diet | pmid:2053355 |
| Stein Y et al. | Metabolism of 3-[3H]sphingosine sphingomyelin labeled with [14C]palmitic or [14C]linoleic acid by Hep G2 cells and rat liver in vivo. | 1991 | Biochim. Biophys. Acta | pmid:2054378 |
| Reaven P et al. | Feasibility of using an oleate-rich diet to reduce the susceptibility of low-density lipoprotein to oxidative modification in humans. | 1991 | Am. J. Clin. Nutr. | pmid:1897476 |
| Uchida Y et al. | Enhancement of keratin synthesis induced by lipokeratinogenoside, N-(O-linoleoyl)-omega-hydroxy fatty acyl sphingosyl glucose, in association with alteration of the intracellular Ca(2+)-content and protein kinase in cultured keratinocytes (FRSK). | 1991 | J. Biochem. | pmid:1715342 |
| Leyton J et al. | Effects of type of dietary fat on phorbol ester-elicited tumor promotion and other events in mouse skin. | 1991 | Cancer Res. | pmid:1899048 |
| Iacono JM and Dougherty RM | Lack of effect of linoleic acid on the high-density-lipoprotein-cholesterol fraction of plasma lipoproteins. | 1991 | Am. J. Clin. Nutr. | pmid:1900384 |
| MacÃas P et al. | Hemin and hemeprotein bleaching during linoleic acid oxidation by lipoxygenases. | 1991 | Biochim. Biophys. Acta | pmid:1903070 |
| Iwahashi H et al. | Isolation and identification of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts formed by the decomposition of the hydroperoxides of linoleic acid, linolenic acid, and arachidonic acid by soybean lipoxygenase. | 1991 | Arch. Biochem. Biophys. | pmid:1846731 |
| Thomson AB et al. | Feeding rats a diet enriched with saturated fatty acids prevents the inhibitory effects of acute and chronic ethanol exposure on the in vitro uptake of hexoses and lipids. | 1991 | Biochim. Biophys. Acta | pmid:1854796 |
| Bellomonte G et al. | Quantitative determination of linoleic acid in infant formulas. | 1991 | Int J Vitam Nutr Res | pmid:1856052 |
| Schmitz PG et al. | Glomerular hemodynamic effects of dietary polyunsaturated fatty acid supplementation. | 1991 | J. Lab. Clin. Med. | pmid:1856576 |
| Eling TE and Glasgow WC | Transduction of the epidermal growth factor mitogenic signal in BALB/c 3T3 fibroblasts involves linoleic acid metabolism. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1825423 |
| Ramasamy S et al. | Linoleic acid-induced endothelial cell injury: role of membrane-bound enzyme activities and lipid oxidation. | 1991 | J. Biochem. Toxicol. | pmid:1831858 |
| Batres-Cerezo R et al. | Studies of women eating diets with different fatty acid composition. III. Fatty acids and prostaglandin synthesis by platelets and cultured human endothelial cells. | 1991 | J Am Coll Nutr | pmid:1894889 |
| Ikeda I et al. | Lymphatic absorption of structured glycerolipids containing medium-chain fatty acids and linoleic acid, and their effect on cholesterol absorption in rats. | 1991 | Lipids | pmid:1895884 |
| van der Schouw YT et al. | Fatty acid composition of serum lipids of mothers and their babies after normal and hypertensive pregnancies. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1815240 |
| Mayer M | Linoleic-acid-dependent slowing of erythrocyte sedimentation in multiple sclerosis. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1815242 |
| James DR et al. | Increased susceptibility to peroxide-induced haemolysis with normal vitamin E concentrations in cystic fibrosis. | 1991 | Clin. Chim. Acta | pmid:1819470 |
| Nègre-Salvayre A et al. | Additional antilipoperoxidant activities of alpha-tocopherol and ascorbic acid on membrane-like systems are potentiated by rutin. | 1991 | Pharmacology | pmid:1652140 |
| Venkatraman JT et al. | Effect of dietary fat on diabetes-induced changes in liver microsomal fatty acid composition and glucose-6-phosphatase activity in rats. | 1991 | Lipids | pmid:1652672 |
| Krumhardt B and Dupont J | The relationship between thromboxane and cytosolic calcium modifiers in rat platelets. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1652770 |
| Huynh S et al. | Metabolic utilization of linoleate and alpha-linolenate in cultured Sertoli cells. | 1991 | Comp. Biochem. Physiol., B | pmid:1684926 |
| de Tomás ME et al. | Metabolic transformation of intracraneally injected [1-14C]linoleic and [1-14C]alpha-linolenic acids in malnourished developing rats. | 1991 | Lipids | pmid:1687158 |
| Owen S et al. | Evidence of free-radical activity in asthma. | 1991 | N. Engl. J. Med. | pmid:1857396 |
| Julu PO and Mutamba A | Comparison of short-term effects of insulin and essential fatty acids on the slowed nerve conduction of streptozotocin diabetes in rats. | 1991 | J. Neurol. Sci. | pmid:1663993 |
| Benmansour N et al. | Effects of castration, dietary fat and adipose tissue sites on adipocyte plasma-membranes cyclic AMP phosphodiesterase activity in the pig. | 1991 | Int. J. Biochem. | pmid:1665423 |
| Cant A et al. | The effect of maternal supplementation with linoleic and gamma-linolenic acids on the fat composition and content of human milk: a placebo-controlled trial. | 1991 | J. Nutr. Sci. Vitaminol. | pmid:1668100 |
| Yamamoto N et al. | Effects of a high-linoleate and a high-alpha-linolenate diet on the learning ability of aged rats. Evidence against an autoxidation-related lipid peroxide theory of aging. | 1991 | J Gerontol | pmid:1670780 |