Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Alopecia D000505 14 associated lipids
Liver Diseases D008107 31 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Acne Vulgaris D000152 35 associated lipids
Melanoma D008545 69 associated lipids
Kidney Diseases D007674 29 associated lipids
Weight Gain D015430 101 associated lipids
Aneurysm D000783 2 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Proteinuria D011507 30 associated lipids
Refsum Disease D012035 19 associated lipids
Alzheimer Disease D000544 76 associated lipids
Hyperplasia D006965 34 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Hoelgaard A and Møllgaard B Permeation of linoleic acid through skin in vitro. 1982 J. Pharm. Pharmacol. pmid:6127396
Letts V et al. Synthesis and utilization of fatty acids by wild-type and fatty acid auxotrophs of Caulobacter crescentus. 1982 J. Bacteriol. pmid:7107555
Enser M and Roberts JL The regulation of hepatic stearoyl-coenzyme A desaturase in obese-hyperglycaemic (ob/ob) mice by food intake and the fatty acid composition of the diet. 1982 Biochem. J. pmid:6128973
Carreau JP et al. Cholesterol synthesis in the liver, kidneys and brain after injection of uniformly 14C-labeled oleic or linoleic acid to developing rats. 1982 Ann. Nutr. Metab. pmid:6814348
Miura S et al. Lymphatic role in the pathogenesis of fat malabsorption in liver cirrhosis in rats. 1982 Dig. Dis. Sci. pmid:7140488
Cuebas D and Schulz H Evidence for a modified pathway of linoleate degradation. Metabolism of 2,4-decadienoyl coenzyme A. 1982 J. Biol. Chem. pmid:7142199
Iritani N and Ikeda Y Activation of catalase and other enzymes by corn oil intake. 1982 J. Nutr. pmid:7143106
Hølmer G et al. Influence of partially hydrogenated vegetable and marine oils on lipid metabolism in rat liver and heart. 1982 Lipids pmid:7144446
Hoffmann P et al. Alterations in renal and aortic prostaglandin E and F formation correlate with blood pressure dietary linoleate deficiency. 1982 Arch Int Pharmacodyn Ther pmid:7181575
Cunnane SC Differential regulation of essential fatty acid metabolism to the prostaglandins: possible basis for the interaction of zinc and copper in biological systems. 1982 Prog. Lipid Res. pmid:7051042
Rosing U et al. Relative fatty acid composition of serum lecithin in the second half of the normal pregnancy. 1982 Gynecol. Obstet. Invest. pmid:7129232
Denning GM et al. Effect of fatty acid modification on prostaglandin production by cultured 3T3 cells. 1982 J. Lipid Res. pmid:6808070
Beaudry GA et al. Stimulation of deacylation in Madin-Darby canine kidney cells. Specificity of deacylation and prostaglandin production in 12-O-tetradecanoylphorbol-13-acetate-treated cells. 1982 J. Biol. Chem. pmid:6809762
Darfler FJ and Insel PA Serum-free culture of resting, PHA-stimulated, and transformed lymphoid cells, including hybridomas. 1982 Exp. Cell Res. pmid:7042376
Melancon SB et al. Oral lecithin and linoleic acid in Friedreich's ataxia: I. Design of the study, material and methods. 1982 Can J Neurol Sci pmid:7049340
Melancon SB et al. Oral lecithin and linoleic acid in Friedreich's ataxia: II. Clinical results. 1982 Can J Neurol Sci pmid:7049341
Hill EG et al. Perturbation of the metabolism of essential fatty acids by dietary partially hydrogenated vegetable oil. 1982 Proc. Natl. Acad. Sci. U.S.A. pmid:6951178
Singh SP et al. Absence of effect of prostaglandins on cholesteryl ester metabolism of 3T3 mouse fibroblasts grown in tissue culture. 1982 Atherosclerosis pmid:6952877
Seward RA et al. Effects of potassium sorbate and other antibotulinal agents on germination and outgrowth of Clostridium botulinum type E spores in microcultures. 1982 Appl. Environ. Microbiol. pmid:6758699
Lange LG Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase. 1982 Proc. Natl. Acad. Sci. U.S.A. pmid:6955782
Hoffmann P et al. Augmented acute hypotensive effect of dihydralazine and clonidine after linoleic acid rich diet in normotensive conscious rats. 1982 Prostaglandins Leukot Med pmid:6955801
Haataja M et al. Prostaglandin precursors in rheumatoid arthritis. 1982 Jan-Feb J. Rheumatol. pmid:7086783
Rationale of the diet-heart statement of the American Heart Association. Report of the AHA nutrition committee. 1982 Mar-Apr Arteriosclerosis pmid:7039581
Goodnight SH et al. Polyunsaturated fatty acids, hyperlipidemia, and thrombosis. 1982 Mar-Apr Arteriosclerosis pmid:7039582
Tobian L et al. Influence of renal prostaglandins and dietary linoleate on hypertension in Dahl S rats. 1982 May-Jun Hypertension pmid:6950924
Kaduce TL et al. Linoleic acid metabolism and prostaglandin production by cultured bovine pulmonary artery endothelial cells. 1982 Sep-Oct Arteriosclerosis pmid:6751307
Rosenthal MD and Whitehurst MC Selective effects of isomeric cis and trans fatty acids on fatty acyl delta 9 and delta 6 desaturation by human skin fibroblasts. 1983 Biochim. Biophys. Acta pmid:6615875
Rosenthal MD and Whitehurst MC Fatty acyl delta 6 desaturation activity of cultured human endothelial cells. Modulation by fetal bovine serum. 1983 Biochim. Biophys. Acta pmid:6297606
Oliw EH Oxygenation of linolenic and linoleic acid to novel vicinal dihydroxy acids by hepatic microsomes of the rabbit. 1983 Biochem. Biophys. Res. Commun. pmid:6301473
Düsing R et al. Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. 1983 Am. J. Physiol. pmid:6337507
Linoleic acid, prostaglandin synthesis and chronic renal failure in rats. 1983 Nutr. Rev. pmid:6341898
Yoshida M et al. Linoleate and fatty acid compositions in the serum lipids of Japanese patients with multiple sclerosis. 1983 Acta Neurol. Scand. pmid:6364685
Rustin P et al. Oxidative interactions between fatty acid peroxy radicals and quinones: possible involvement in cyanide-resistant electron transport in plant mitochondria. 1983 Arch. Biochem. Biophys. pmid:6414377
Anggård E Ethanol, essential fatty acids and prostaglandins. 1983 Pharmacol. Biochem. Behav. pmid:6415673
Shechter G and Grossman S Lipoxygenase from baker's yeast: purification and properties. 1983 Int. J. Biochem. pmid:6416906
Campbell TB and Lueking DR Long-chain fatty acid assimilation By rhodopseudomonas sphaeroides. 1983 J. Bacteriol. pmid:6600450
Nemoto N and Takayama S Effects of unsaturated fatty acids on metabolism of benzo[a]pyrene in an NADPH-fortified rat liver microsomal system. 1983 Carcinogenesis pmid:6311450
Horrobin DF and Manku MS How do polyunsaturated fatty acids lower plasma cholesterol levels? 1983 Lipids pmid:6312241
Høy CE et al. Acyl group distributions in tissue lipids of rats fed evening primrose oil (gamma -linolenic plus linoleic acid) or soybean oil (alpha-linolenic plus linoleic acid). 1983 Lipids pmid:6318009
Nicholson T and Omer SA The application of cumulative sum analysis to the investigation of reticulum motility in ruminant animals. 1983 Zentralbl Veterinarmed A pmid:6318476
Kirstein D et al. Effect of dietary fats on the delta 6- and delta 5-desaturation of fatty acids in rat liver microsomes. 1983 Br. J. Nutr. pmid:6315055
Spector AA et al. Eicosapentaenoic acid and prostacyclin production by cultured human endothelial cells. 1983 J. Lipid Res. pmid:6321621
Sanders TA Dietary fat and platelet function. 1983 Clin. Sci. pmid:6309463
Goldmacher VS Immobilization of protein molecules on liposomes. Anchorage by artificially bound unsaturated hydrocarbon tails. 1983 Biochem. Pharmacol. pmid:6189496
Gerzer R et al. Calcium-induced release from platelet membranes of fatty acids that modulate soluble guanylate cyclase. 1983 J. Pharmacol. Exp. Ther. pmid:6134818
Frankel EN Volatile lipid oxidation products. 1983 Prog. Lipid Res. pmid:6306693
Gere A et al. Fatty acid composition of human milk and milk-based formulas in Hungary. 1983 Acta Paediatr Hung pmid:6613576
Lloyd D et al. Adaptive changes in yeast membranes: catabolite repression and oxygen. 1983 Biochem. Soc. Trans. pmid:6617968
Eckart J et al. [Current status of parenteral feeding with fat emulsions. Clinical experiences with infected patients]. 1983 Infusionsther Klin Ernahr pmid:6618658
Derambure S et al. [Platelet aggregation and platelet and plasma fatty acid levels in the child with migraine. Apropos of 40 case reports]. 1983 Pediatrie pmid:6674921
Kreutter D et al. The effect of essential fatty acid deficiency on the stimulation of intestinal calcium transport by 1,25-dihydroxyvitamin D3. 1983 J. Biol. Chem. pmid:6687596
Lejman W et al. Increase in the linoleic acid level in pulmonary surfactant in the rabbit after exposure to high oxygen concentration. 1983 Folia Biol. (Krakow) pmid:6689156
Shand JH and Noble RC The characterization of the linoleic acid desaturation and elongation system in ovine placental tissue. 1983 Int. J. Biochem. pmid:6642054
Rapp JH et al. Lipids of human atherosclerotic plaques and xanthomas: clues to the mechanism of plaque progression. 1983 J. Lipid Res. pmid:6644183
Jones R et al. The analysis of the red cell unsaturated fatty acid test for multiple sclerosis using laser cytopherometry. 1983 Phys Med Biol pmid:6647546
MacDonald ML et al. Role of linoleate as an essential fatty acid for the cat independent of arachidonate synthesis. 1983 J. Nutr. pmid:6408230
Gavigan SJ and Knight BL The effects of low-density lipoprotein and cholesterol on acyl-coenzyme A: cholesterol acyltransferase activity in membranes from cultured human fibroblasts. 1983 Biochem. J. pmid:6651782
Jones R et al. Monitoring changes in the blood of patients with multiple sclerosis. 1983 Prog. Brain Res. pmid:6665128
Hoover RL et al. Role of cholesterol in the capping of surface immunoglobulin receptors on murine lymphocytes. 1983 J. Cell Biol. pmid:6223042
George AM et al. Effect of membrane fatty acid changes on the radiation sensitivity of human lymphoid cells. 1983 Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. pmid:6601634
Greenway DL and Dyke KG The effect of membrane-bound beta-lactamase on linoleic acid sensitivity in Staphylococcus aureus. 1983 J. Gen. Microbiol. pmid:6605415
Pavelka M and Gangl A Effects of colchicine on the intestinal transport of endogenous lipid. Ultrastructural, biochemical, and radiochemical studies in fasting rats. 1983 Gastroenterology pmid:6822325
Breton M et al. Linoleate incorporation into rat liver membranes phospholipids: effect on plasma membrane ATPase activities and physical properties. 1983 Biochem. Biophys. Res. Commun. pmid:6230079
Monnier LH et al. Plasma lipid fatty acids and platelet function in insulin-dependent diabetic patients. 1983 Diabete Metab pmid:6230269
O'Brien PM and Broughton Pipkin F The effect of essential fatty acid and specific vitamin supplements on vascular sensitivity in the mid-trimester of human pregnancy. 1983 Clin Exp Hypertens B pmid:6872286
Purvis JM et al. Chain elongation-desaturation of linoleic acid during the development of the pig. Implications for the supply of polyenoic fatty acids to the developing brain. 1983 Comp. Biochem. Physiol., B pmid:6872512
Weber EJ Variation in corn (Zea mays L.) for fatty acid compositions of triglycerides and phospholipids. 1983 Biochem. Genet. pmid:6838482
Cho BH Lipid composition and cholesterol esterifying activity in microsomal preparations of porcine coronary arteries and heart tissue. 1983 Biochem Med pmid:6838501
Shultz TD and Leklem JE Selenium status of vegeterians, nonvegetarians, and hormone-dependent cancer subjects. 1983 Am. J. Clin. Nutr. pmid:6849273
Charnock JS et al. Differences in the fatty acid composition of atrial and ventricular phospholipids of rat heart following standard and lipid-supplemented diets. 1983 Comp. Biochem. Physiol., B pmid:6851485
Arudi RL et al. Purification of oleic acid and linoleic acid. 1983 J. Lipid Res. pmid:6854155
Kanner J and Kinsella JE Initiation of lipid peroxidation by a peroxidase/hydrogen peroxide/halide system. 1983 Lipids pmid:6855480
Glick JM and Adelman SJ Established cell lines from rat adipose tissue that secrete lipoprotein lipase. 1983 In Vitro pmid:6862515
Ookhtens M and Baker N Incomplete free fatty acid oxidation by ascites tumor cells under low oxygen tension. 1983 Am. J. Physiol. pmid:6295191
Ries W et al. Selected metabolic results of the Leipzig gerontological longitudinal study. 1983 Mar-Apr Z Alternsforsch pmid:6868654
Hoffmann P et al. Impaired catecholamine inactivation. A prohypertensive stimulus after dietary linoleate deficiency in salt-loaded rats? 1983 Nov-Dec Hypertension pmid:6581124
Sanders TA et al. The influence of a maternal diet rich in linoleic acid on brain and retinal docosahexaenoic acid in the rat. 1984 Br. J. Nutr. pmid:6228249
Enig MG et al. Trans-unsaturated fatty acids in margarines and human subcutaneous fat in Israel. 1984 Hum Nutr Clin Nutr pmid:6086551
Booyens J et al. Some effects of linoleic acid and gamma-linolenic acid on the proliferation of human hepatoma cells in culture. 1984 S. Afr. Med. J. pmid:6324395
Kitagawa S et al. Effects of four types of reagents on ADP-induced aggregation and Ca2+ mobilization of bovine blood platelets. 1984 Biochim. Biophys. Acta pmid:6324876
Simon I et al. Electron-spin resonance studies of lipid-modified microsomes from Friend erythroleukemia cells. 1984 Biochim. Biophys. Acta pmid:6326852
Manku MS et al. Essential fatty acids in the plasma phospholipids of patients with atopic eczema. 1984 Br. J. Dermatol. pmid:6329254
Schick PK et al. Arachidonate synthesis and uptake in isolated guinea-pig megakaryocytes and platelets. 1984 Biochim. Biophys. Acta pmid:6433984
Furukawa M et al. Studies on arachidonate 5-lipoxygenase of rat basophilic leukemia cells. 1984 Biochim. Biophys. Acta pmid:6089906
Becker W Distribution of 14C after oral administration of [1-14C]linoleic acid in rats fed different levels of essential fatty acids. 1984 J. Nutr. pmid:6470826
Iritani N et al. Physiological impairment in linoleic acid deficiency of rats and the effect of n-3 polyunsaturated fatty acids. 1984 J. Nutr. Sci. Vitaminol. pmid:6470835
Rogiers V et al. Abnormal fatty acid turnover in the phospholipids of the red blood cell membranes of cystic fibrosis patients (in vitro study). 1984 Pediatr. Res. pmid:6472942
Noble RC et al. Lipid composition of the bovine epidermis. 1984 Res. Vet. Sci. pmid:6473909
Heine RJ et al. The effect of dietary linoleic acid and pectin on lipoprotein and apolipoprotein A1 concentrations in rhesus monkeys. 1984 Ann. Nutr. Metab. pmid:6476785
Marzouki ZM and Coniglio JG The effects of hypophysectomy and testosterone treatment on the composition and metabolism of testicular lipids. 1984 Lipids pmid:6482683
Adam O and Wolfram G Effect of different linoleic acid intakes on prostaglandin biosynthesis and kidney function in man. 1984 Am. J. Clin. Nutr. pmid:6486083
Pratsch L et al. Interaction of fusogen substances with the erythrocyte membrane. 1984 Biomed. Biochim. Acta pmid:6487285
Alao SJ and Balnave D Growth and carcass composition of broilers fed sunflower oil and olive oil. 1984 Br. Poult. Sci. pmid:6733552
Huang YS et al. Effect of dietary depletion and repletion of linoleic acid on renal fatty acid composition and urinary prostaglandin excretion. 1984 Prostaglandins Leukot Med pmid:6593743
Margetts BM et al. Dietary fats and blood pressure. 1984 Aust N Z J Med pmid:6596055
Eyssen H and Verhulst A Biotransformation of linoleic acid and bile acids by Eubacterium lentum. 1984 Appl. Environ. Microbiol. pmid:6582800
Strong AM et al. Prostaglandin precursors in plasma phospholipids of patients with psoriasis: effects of treatment with coal tar. 1984 Prostaglandins Leukot Med pmid:6588390
Cunnane SC et al. Linoleic acid and arachidonic acid metabolism in human peripheral blood leucocytes: comparison with the rat. 1984 Br. J. Nutr. pmid:6422980
Singer P et al. Age-dependent alterations of linoleic, arachidonic and eicosapentaenoic acids in renal cortex and medulla of spontaneously hypertensive rats. 1984 Prostaglandins pmid:6328578
Asakawa T et al. Ca2+-activated, fatty acid-dependent guanylate cyclase in synaptic plasma membranes and its requirement for Ca2+ and Mg-GTP in the activation. 1984 Adv. Exp. Med. Biol. pmid:6149673