Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Napolitano A et al. | Reactions of hydro(pero)xy derivatives of polyunsaturated fatty acids/esters with nitrite ions under acidic conditions. Unusual nitrosative breakdown of methyl 13-hydro(pero)xyoctadeca-9,11-dienoate to a novel 4-nitro-2-oximinoalk-3-enal product. | 2002 | J. Org. Chem. | pmid:11846653 |
Calder PC | Conjugated linoleic acid in humans--reasons to be cheerful? | 2002 | Curr Opin Clin Nutr Metab Care | pmid:11844976 |
Ramirez DC and Gimenez MS | Lipid modification in mouse peritoneal macrophages after chronic cadmium exposure. | 2002 | Toxicology | pmid:11844611 |
Cahoon EB et al. | Transgenic production of epoxy fatty acids by expression of a cytochrome P450 enzyme from Euphorbia lagascae seed. | 2002 | Plant Physiol. | pmid:11842164 |
Krutetskaia ZI et al. | [Effect of arachidonic and other fatty acids on the intracellular calcium concentration and calcium signaling in peritoneal macrophages]. | 2001 | Tsitologiia | pmid:11840781 |
Lemaitre RN et al. | Cell membrane trans-fatty acids and the risk of primary cardiac arrest. | 2002 | Circulation | pmid:11839624 |
Minemoto Y et al. | Oxidation of linoleic acid encapsulated with gum arabic or maltodextrin by spray-drying. | 2002 Mar-Apr | J Microencapsul | pmid:11837973 |
Joo ST et al. | Effects of dietary conjugated linoleic acid on fatty acid composition, lipid oxidation, color, and water-holding capacity of pork loin. | 2002 | J. Anim. Sci. | pmid:11831506 |
Baron CP et al. | Concentration effects in myoglobin-catalyzed peroxidation of linoleate. | 2002 | J. Agric. Food Chem. | pmid:11829662 |
Raes K et al. | The deposition of conjugated linoleic acids in eggs of laying hens fed diets varying in fat level and fatty acid profile. | 2002 | J. Nutr. | pmid:11823576 |
Mitchell LA et al. | Linoleic acid, cis-epoxyoctadecenoic acids, and dihydroxyoctadecadienoic acids are toxic to Sf-21 cells in the absence of albumin. | 2002 | Toxicol. Lett. | pmid:11814707 |
Kawajiri H et al. | Arachidonic and linoleic acid metabolism in mouse intestinal tissue: evidence for novel lipoxygenase activity. | 2002 | Arch. Biochem. Biophys. | pmid:11811948 |
Ulusu NN et al. | Abietic acid inhibits lipoxygenase activity. | 2002 | Phytother Res | pmid:11807975 |
McCarthy-Beckett DO | Dietary supplementation with conjugated linoleic acid does not improve nutritional status of tumor-bearing rats. | 2002 | Res Nurs Health | pmid:11807919 |
Wang CT et al. | A calcium-independent phospholipase activity insensitive to bromoenol lactone mediates arachidonic acid release by lindane in rat myometrial cells. | 2001 | Life Sci. | pmid:11798014 |
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Milne GL and Porter NA | Separation and identification of phospholipid peroxidation products. | 2001 | Lipids | pmid:11795860 |
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Demmelmair H et al. | Investigation of long-chain polyunsaturated fatty acid metabolism in lactating women by means of stable isotope techniques. | 2001 | Adv. Exp. Med. Biol. | pmid:11787680 |
Agostoni C et al. | Long-chain polyunsaturated fatty acid concentrations in human hindmilk are constant throughout twelve months of lactation. | 2001 | Adv. Exp. Med. Biol. | pmid:11787678 |
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Miller A et al. | Modulation of arachidonic acid distribution by conjugated linoleic acid isomers and linoleic acid in MCF-7 and SW480 cancer cells. | 2001 | Lipids | pmid:11768161 |
Chuang LT et al. | Inhibitory effect of conjugated linoleic acid on linoleic acid elongation in transformed yeast with human elongase. | 2001 | Lipids | pmid:11768153 |
Eggert JM et al. | Effects of conjugated linoleic acid on the belly firmness and fatty acid composition of genetically lean pigs. | 2001 | J. Anim. Sci. | pmid:11768116 |
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Park Y and Pariza MW | Lipoxygenase inhibitors inhibit heparin-releasable lipoprotein lipase activity in 3T3-L1 adipocytes and enhance body fat reduction in mice by conjugated linoleic acid. | 2001 | Biochim. Biophys. Acta | pmid:11750884 |
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Fernández-Real JM et al. | Circulating granulocyte-macrophage colony-stimulating factor and serum fatty acid composition in men and women. | 2001 | Metab. Clin. Exp. | pmid:11735097 |
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Gustafsson MC et al. | Fatty-acid-displaced transcriptional repressor, a conserved regulator of cytochrome P450 102 transcription in Bacillus species. | 2001 | Arch. Microbiol. | pmid:11734890 |
Watanabe T et al. | Production and chemiluminescent free radical reactions of glyoxal in lipid peroxidation of linoleic acid by the ligninolytic enzyme, manganese peroxidase. | 2001 | Eur. J. Biochem. | pmid:11733005 |
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Peters JM et al. | Influence of conjugated linoleic acid on body composition and target gene expression in peroxisome proliferator-activated receptor alpha-null mice. | 2001 | Biochim. Biophys. Acta | pmid:11731333 |
Park Y and Pariza MW | The effects of dietary conjugated nonadecadienoic acid on body composition in mice. | 2001 | Biochim. Biophys. Acta | pmid:11731328 |
Villalpando S et al. | [13C]linoleic acid oxidation and transfer into milk in stunted lactating women with contrasting body mass indexes. | 2001 | Am. J. Clin. Nutr. | pmid:11729835 |
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Cunnane SC | Application of new methods and analytical approaches to research on polyunsaturated fatty acid homeostasis. | 2001 | Lipids | pmid:11724470 |
Makrides M et al. | Perinatal characteristics may influence the outcome of visual acuity. | 2001 | Lipids | pmid:11724461 |
Calder PC | Polyunsaturated fatty acids, inflammation, and immunity. | 2001 | Lipids | pmid:11724453 |
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Milani G et al. | Respiratory chain network in mitochondria of Candida parapsilosis: ADP/O appraisal of the multiple electron pathways. | 2001 | FEBS Lett. | pmid:11718721 |
Palinski W et al. | Maternal hypercholesterolemia and treatment during pregnancy influence the long-term progression of atherosclerosis in offspring of rabbits. | 2001 | Circ. Res. | pmid:11717155 |