Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hansen HS and Jensen B | Essential function of linoleic acid esterified in acylglucosylceramide and acylceramide in maintaining the epidermal water permeability barrier. Evidence from feeding studies with oleate, linoleate, arachidonate, columbinate and alpha-linolenate. | 1985 | Biochim. Biophys. Acta | pmid:3922424 |
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Allen RE et al. | A serum-free medium that supports the growth of cultured skeletal muscle satellite cells. | 1985 | In Vitro Cell. Dev. Biol. | pmid:3905759 |
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Allen RE et al. | Effect of insulin and linoleic acid on satellite cell differentiation. | 1985 | J. Anim. Sci. | pmid:3894312 |
Calderbank J et al. | Plasma-membrane phospholipid unsaturation affects expression of the general amino-acid permease in Saccharomyces cerevisiae Y185. | 1985 | J. Gen. Microbiol. | pmid:3886834 |
Jäntti J et al. | Linoleic acid treatment in inflammatory arthritis. | 1985 | Int J Clin Pharmacol Ther Toxicol | pmid:3886567 |
Moilanen T et al. | Atherosclerosis precursors in Finnish children and adolescents. V. Fatty acid composition of serum cholesteryl esters: regional differences in Finland. | 1985 | Acta Paediatr Scand Suppl | pmid:3867222 |
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Montalto MB and Benson JD | Nutrient intakes of older infants: effect of different milk feedings. | 1986 | J Am Coll Nutr | pmid:3771945 |
Kanazawa K et al. | The effect of orally administered secondary autoxidation products of linoleic acid on the activity of detoxifying enzymes in the rat liver. | 1986 | Biochim. Biophys. Acta | pmid:3768385 |
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Hachey DL et al. | Human lactation: maternal transfer of dietary triglycerides labeled with stable isotopes. | 1987 | J. Lipid Res. | pmid:3681142 |
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Loscalzo J et al. | Unsaturated fatty acids enhance low density lipoprotein uptake and degradation by peripheral blood mononuclear cells. | 1987 Sep-Oct | Arteriosclerosis | pmid:3675304 |
Heifets M et al. | Effect of dietary lipids on renal function in rats with subtotal nephrectomy. | 1987 | Kidney Int. | pmid:3669493 |
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