Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Am. J. Physiol., Cell Physiol. (1)
- Hypertension (1)
- Others (3)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Am. J. Physiol., Cell Physiol. (1)
- Plant Cell (1)
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nanji AA and Narod S | Multiple sclerosis, latitude and dietary fat: is pork the missing link? | 1986 | Med. Hypotheses | pmid:3638477 |
| Heleniak EP and Lamola SW | A new prostaglandin disturbance syndrome in schizophrenia: delta-6-pyroluria. | 1986 | Med. Hypotheses | pmid:3520252 |
| ROTH OA | [Improved wound healing through linoleic and linolenic acid]. | 1951 | Med Welt | pmid:14882090 |
| SOSNOVSKII AT | [TREATMENT OF EXPERIMENTAL RADIATION INJURY TO THE SKIN WITH CYGEROL AND LINOL]. | 1964 | Med Radiol (Mosk) | pmid:14234245 |
| Poompachee K and Chudapongse N | Comparison of the antioxidant and cytotoxic activities of Phyllanthus virgatus and Phyllanthus amarus extracts. | 2012 | Med Princ Pract | pmid:22024634 |
| Pariza MW and Ha YL | Conjugated dienoic derivatives of linoleic acid: a new class of anticarcinogens. | 1990 | Med Oncol Tumor Pharmacother | pmid:2232933 |
| KRITCHEVSKY D and TEPPER SA | INFLUENCE OF FATTY ACIDS ON SERUM AND LIVER CHOLESTEROL IN RATS. | 1964 | Med Exp Int J Exp Med | pmid:14165723 |
| Haro AM et al. | [Linoleic conjugated acid: current interest in human nutrition]. | 2006 | Med Clin (Barc) | pmid:17043006 |
| Campoy C et al. | [Update of knowledge, recommendations and full consensus about the role of long chain polyunsaturated fatty acids in pregnancy, lactating period and first year of life.Asociación Española de PediatrÃa. Sociedad Española de GinecologÃa y Obstetricia. Sociedad Española de Nutrición Comunitaria. Academia Española deNutrición y Ciencias de la Alimentación]. | 2010 | Med Clin (Barc) | pmid:20434734 |
| Sohal RS et al. | Relationship between lipofuscin granules and polyunsaturated fatty acids in the housefly, Musca domestica. | 1984 | Mech. Ageing Dev. | pmid:6330462 |
| Spiteller G | Peroxidation of linoleic acid and its relation to aging and age dependent diseases. | 2001 | Mech. Ageing Dev. | pmid:11322990 |
| Jung S et al. | Effect of dietary mixture of gallic acid and linoleic acid on antioxidative potential and quality of breast meat from broilers. | 2010 | Meat Sci. | pmid:20609528 |
| Jacob RH et al. | Phenotypic characterisation of colour stability of lamb meat. | 2014 | Meat Sci. | pmid:23415827 |
| Moloney AP et al. | Colour of fat, and colour, fatty acid composition and sensory characteristics of muscle from heifers offered alternative forages to grass silage in a finishing ration. | 2013 | Meat Sci. | pmid:23806853 |
| Van Ba H et al. | Significant influence of particular unsaturated fatty acids and pH on the volatile compounds in meat-like model systems. | 2013 | Meat Sci. | pmid:23632107 |
| Zamora-Rojas E et al. | Prediction of fatty acids content in pig adipose tissue by near infrared spectroscopy: at-line versus in-situ analysis. | 2013 | Meat Sci. | pmid:23793086 |
| Dal Bosco A et al. | Effect of dietary alfalfa on the fatty acid composition and indexes of lipid metabolism of rabbit meat. | 2014 | Meat Sci. | pmid:24036258 |
| Jin G et al. | Crude lipoxygenase from pig muscle: partial characterization and interactions of temperature, NaCl and pH on its activity. | 2011 | Meat Sci. | pmid:21093161 |
| Toomik P et al. | The effect of tenderizing acids on linoleic acid oxidation during marination of pork. | 2012 | Meat Sci. | pmid:22762994 |
| Tume RK et al. | Enriching M. sternomandibularis with alpha-tocopherol by dietary means does not protect against the lipid oxidation caused by high-pressure processing. | 2010 | Meat Sci. | pmid:20374755 |
| Berthelot V et al. | Utilization of extruded linseed to modify fatty composition of intensively-reared lamb meat: effect of associated cereals (wheat vs. corn) and linoleic acid content of the diet. | 2010 | Meat Sci. | pmid:20374762 |
| Della Casa G et al. | Performance and fat quality of heavy pigs fed maize differing in linoleic acid content. | 2010 | Meat Sci. | pmid:20374768 |
| Aldai N et al. | Double-muscling character influences the trans-18:1 and conjugated linoleic acid profiles in concentrate-fed yearling bulls. | 2010 | Meat Sci. | pmid:20374865 |
| Song S et al. | Identification of pork flavour precursors from enzyme-treated lard using Maillard model system assessed by GC-MS and partial least squares regression. | 2017 | Meat Sci. | pmid:27792915 |
| Hoffman LC et al. | Lipid and protein stability and sensory evaluation of ostrich (Struthio camelus) droëwors with the addition of rooibos tea extract (Aspalathus linearis) as a natural antioxidant. | 2014 | Meat Sci. | pmid:24334052 |
| Cannata S et al. | Effect of visual marbling on sensory properties and quality traits of pork loin. | 2010 | Meat Sci. | pmid:20416803 |
| Jokela H et al. | Fatty acid and cholesterol composition of the uterine artery intima in relation to menopausal status, age, and serum cholesterol. | 2004 | Maturitas | pmid:14757270 |
| Yang Z and Huffman SL | Modelling linoleic acid and α-linolenic acid requirements for infants and young children in developing countries. | 2013 | Matern Child Nutr | pmid:23167585 |
| Gibson RA et al. | Conversion of linoleic acid and alpha-linolenic acid to long-chain polyunsaturated fatty acids (LCPUFAs), with a focus on pregnancy, lactation and the first 2 years of life. | 2011 | Matern Child Nutr | pmid:21366864 |
| Lauritzen L and Carlson SE | Maternal fatty acid status during pregnancy and lactation and relation to newborn and infant status. | 2011 | Matern Child Nutr | pmid:21366866 |
| Brenna JT | Animal studies of the functional consequences of suboptimal polyunsaturated fatty acid status during pregnancy, lactation and early post-natal life. | 2011 | Matern Child Nutr | pmid:21366867 |
| Briend A et al. | Fatty acid status in early life in low-income countries--overview of the situation, policy and research priorities. | 2011 | Matern Child Nutr | pmid:21366873 |
| Parra-Cabrera S et al. | Dietary intakes of polyunsaturated fatty acids among pregnant Mexican women. | 2011 | Matern Child Nutr | pmid:21410881 |
| Marinho GS et al. | Lipids and Composition of Fatty Acids of Saccharina latissima Cultivated Year-Round in Integrated Multi-Trophic Aquaculture. | 2015 | Mar Drugs | pmid:26184241 |
| Delmas-Beauvieux MC et al. | Liposomes as fatty acids carriers in isolated rat liver: effect on energy metabolism and on isolated mitochondria activity. | 2000 | MAGMA | pmid:10697225 |
| MAYOUX et al. | [Not Available]. | 1949 | Lyon Med | pmid:18136286 |
| Stantcheva IG et al. | Metabolic fate of fatty acids in type II cells isolated from adult rat lung. | 1982 | Lung | pmid:7121064 |
| Yoshiki Y et al. | Chemiluminescence and reactive oxygen scavenging activities of the hydrogen peroxide/gallic acid/lactoperoxidase system. | 2000 May-Jun | Luminescence | pmid:10862147 |
| Rondanelli M et al. | Effects of two-months balanced diet in metabolically healthy obesity: lipid correlations with gender and BMI-related differences. | 2015 | Lipids Health Dis | pmid:26511930 |
| Min JS et al. | Monitoring the formation of cholesterol oxidation products in model systems using response surface methodology. | 2015 | Lipids Health Dis | pmid:26201850 |
| Song Y et al. | Polyunsaturated fatty acid relatively decreases cholesterol content in THP-1 macrophage-derived foam cell: partly correlates with expression profile of CIDE and PAT members. | 2013 | Lipids Health Dis | pmid:23879935 |
| Al-Taan O et al. | Changes in plasma and erythrocyte omega-6 and omega-3 fatty acids in response to intravenous supply of omega-3 fatty acids in patients with hepatic colorectal metastases. | 2013 | Lipids Health Dis | pmid:23648075 |
| Cedernaes J et al. | Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet. | 2013 | Lipids Health Dis | pmid:23298201 |
| Tang KS | Protective effect of arachidonic acid and linoleic acid on 1-methyl-4-phenylpyridinium-induced toxicity in PC12 cells. | 2014 | Lipids Health Dis | pmid:25522984 |
| Maruyama H et al. | Linoleate appears to protect against palmitate-induced inflammation in Huh7 cells. | 2014 | Lipids Health Dis | pmid:24885871 |
| Dai J et al. | Effects of polyunsaturated fatty acids on the growth of gastric cancer cells in vitro. | 2013 | Lipids Health Dis | pmid:23663688 |
| Nasrollahzadeh J et al. | The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression. | 2008 | Lipids Health Dis | pmid:19014610 |
| Høstmark AT and Haug A | Percentage oleic acid is inversely related to percentage arachidonic acid in total lipids of rat serum. | 2013 | Lipids Health Dis | pmid:23521743 |
| Shen J et al. | Effect of essential fatty acids on glucose-induced cytotoxicity to retinal vascular endothelial cells. | 2012 | Lipids Health Dis | pmid:22781401 |
| Bjørkkjaer T et al. | Short-term duodenal seal oil administration normalised n-6 to n-3 fatty acid ratio in rectal mucosa and ameliorated bodily pain in patients with inflammatory bowel disease. | 2006 | Lipids Health Dis | pmid:16549021 |
| Muralikumar S et al. | Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties. | 2017 | Lipids Health Dis | pmid:28109294 |
| Monteiro J et al. | Menhaden oil, but not safflower or soybean oil, aids in restoring the polyunsaturated fatty acid profile in the novel delta-6-desaturase null mouse. | 2012 | Lipids Health Dis | pmid:22642787 |
| Karupaiah T et al. | Comparing effects of soybean oil- and palm olein-based mayonnaise consumption on the plasma lipid and lipoprotein profiles in human subjects: a double-blind randomized controlled trial with cross-over design. | 2016 | Lipids Health Dis | pmid:27535127 |
| Lu X et al. | Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction. | 2010 | Lipids Health Dis | pmid:20868498 |
| Ruyter B et al. | Influence of temperature and high dietary linoleic acid content on esterification, elongation, and desaturation of PUFA in Atlantic salmon hepatocytes. | 2003 | Lipids | pmid:14577662 |
| Labbe C et al. | Thermal acclimation and dietary lipids alter the composition, but not fluidity, of trout sperm plasma membrane. | 1995 | Lipids | pmid:7760685 |
| Brown JE et al. | Linoleic acid metabolism in the spontaneously diabetic rat: delta6-desaturase activity vs. product/precursor ratios. | 2000 | Lipids | pmid:11201993 |
| Li Z et al. | Hepatic microsomal and peroxisomal docosahexaenoate biosynthesis during piglet development. | 2000 | Lipids | pmid:11201994 |
| Pepin D et al. | Essential fatty acid pattern of glycerolipids in rat hepatocytes in primary culture and in coculture with rat liver epithelial cells. | 1988 | Lipids | pmid:3185111 |
| Takahashi R and Horrobin DF | Linoleic acid-induced fatty acid changes in platelet and aorta of the rat: effect of age and cholesterol. | 1988 | Lipids | pmid:3185125 |
| Carvajal O et al. | Effect of medium-chain fatty acid positional distribution in dietary triacylglycerol on lymphatic lipid transport and chylomicron composition in rats. | 2000 | Lipids | pmid:11201996 |
| Høy CE and Hølmer G | Dietary linoleic acid and the fatty acid profiles in rats fed partially hydrogenated marine oils. | 1988 | Lipids | pmid:3200121 |
| Wien M et al. | Decreasing the linoleic acid to alpha-linolenic acid diet ratio increases eicosapentaenoic acid in erythrocytes in adults. | 2010 | Lipids | pmid:20496049 |
| Høy CE et al. | Acyl group distributions in tissue lipids of rats fed evening primrose oil (gamma -linolenic plus linoleic acid) or soybean oil (alpha-linolenic plus linoleic acid). | 1983 | Lipids | pmid:6318009 |
| Palombo JD et al. | Metabolism of dietary alpha-linolenic acid vs. eicosapentaenoic acid in rat immune cell phospholipids during endotoxemia. | 1998 | Lipids | pmid:9870905 |
| Zambell KL et al. | Conjugated linoleic acid supplementation in humans: effects on fatty acid and glycerol kinetics. | 2001 | Lipids | pmid:11592726 |
| Smedman A and Vessby B | Conjugated linoleic acid supplementation in humans--metabolic effects. | 2001 | Lipids | pmid:11592727 |
| Risérus U et al. | CLA and body weight regulation in humans. | 2003 | Lipids | pmid:12733745 |
| Gruffat D et al. | In vitro comparison of hepatic metabolism of 9cis-11 trans and 10trans-12cis isomers of CLA in the rat. | 2003 | Lipids | pmid:12733748 |
| Cunnane SC and Wahle KW | Zinc deficiency increases the rate of delta 6 desaturation of linoleic acid in rat mammary tissue. | 1981 | Lipids | pmid:7300596 |
| Scislowski V et al. | Dietary linoleic acid-induced hypercholesterolemia and accumulation of very light HDL in steers. | 2004 | Lipids | pmid:15134139 |
| Kanazawa K et al. | Uptake of secondary autoxidation products of linoleic acid by the rat. | 1985 | Lipids | pmid:4033361 |
| Kelley DS et al. | Dietary supplementation with conjugated linoleic acid increased its concentration in human peripheral blood mononuclear cells, but did not alter their function. | 2001 | Lipids | pmid:11521964 |
| Pratt VC et al. | Fatty acid content of plasma lipids and erythrocyte phospholipids are altered following burn injury. | 2001 | Lipids | pmid:11521965 |
| Bryan DL et al. | Incorporation of alpha-linolenic acid and linoleic acid into human respiratory epithelial cell lines. | 2001 | Lipids | pmid:11521969 |
| Ziboh VA | The significance of polyunsaturated fatty acids in cutaneous biology. | 1996 | Lipids | pmid:8729128 |
| Kwan KY et al. | Inhibitory effect of linoleic acid on chain elongation and desaturation of 18:2 c,t isomers in lactating and neonatal rats. | 1998 | Lipids | pmid:9590629 |
| Emken EA et al. | Effect of dietary arachidonic acid on metabolism of deuterated linoleic acid by adult male subjects. | 1998 | Lipids | pmid:9625594 |
| Lin KC et al. | Esterification of fatty acids by bovine intramuscular and subcutaneous adipose tissues. | 1992 | Lipids | pmid:1349716 |
| Ramirez AM et al. | A trichome-specific linoleate lipoxygenase expressed during pyrethrin biosynthesis in pyrethrum. | 2013 | Lipids | pmid:23893337 |
| Nassar BA et al. | The influence of dietary manipulation with n-3 and n-6 fatty acids on liver and plasma phospholipid fatty acids in rats. | 1986 | Lipids | pmid:3796229 |
| de Gomez Dumm IN et al. | Effect of malonyl-CoA on delta 6 desaturation activity of rat liver microsomes. | 1986 | Lipids | pmid:3796237 |
| Oh-hashi K et al. | Dietary alpha-linolenate suppresses endotoxin-induced platelet-activating factor production in rat kidney. | 1999 | Lipids | pmid:10188594 |
| Huang YS et al. | Effect of dietary linoleic acid content on the distribution of triacylglycerol molecular species in rat adipose tissue. | 1992 | Lipids | pmid:1487970 |
| Sugiyama K et al. | Dietary methionine level affects linoleic acid metabolism through phosphatidylethanolamine N-methylation in rats. | 1998 | Lipids | pmid:9560797 |
| Chen HW et al. | Gender and dietary fat affect alpha-tocopherol status in F344/N rats. | 1992 | Lipids | pmid:1491600 |
| You YQ et al. | Effect of continuous enteral medium-chain fatty acid infusion on lipid metabolism in rats. | 1998 | Lipids | pmid:9560800 |
| Venkatraman JT et al. | Effect of dietary fat on diabetes-induced changes in liver microsomal fatty acid composition and glucose-6-phosphatase activity in rats. | 1991 | Lipids | pmid:1652672 |
| Laganiere S and Fernandes G | Study on the lipid composition of aging Fischer-344 rat lymphoid cells: effect of long-term calorie restriction. | 1991 | Lipids | pmid:1881243 |
| Chen ZY et al. | Linoleoyl-enriched triacylglycerol species increase in maternal liver during late pregnancy in the rat. | 1992 | Lipids | pmid:1608298 |
| Kanner J et al. | Nitric oxide, an inhibitor of lipid oxidation by lipoxygenase, cyclooxygenase and hemoglobin. | 1992 | Lipids | pmid:1608303 |
| Schmid PC et al. | Generation and remodeling of highly polyunsaturated molecular species of rat hepatocyte phospholipids. | 1997 | Lipids | pmid:9397404 |
| Sjövall O et al. | Elution factors of synthetic oxotriacylglycerols as an aid in identification of peroxidized natural triacylglycerols by reverse-phase high-performance liquid chromatography with electrospray mass spectrometry. | 1997 | Lipids | pmid:9397407 |
| Christie WW et al. | Isomers in commercial samples of conjugated linoleic acid. | 1997 | Lipids | pmid:9397410 |
| Su HM et al. | Increasing dietary linoleic acid in young rats increases and then decreases docosahexaenoic acid in retina but not in brain. | 1996 | Lipids | pmid:8972463 |
| Benito P et al. | The effect of conjugated linoleic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. | 2001 | Lipids | pmid:11337976 |
| Benito P et al. | The effect of conjugated linoleic acid on plasma lipoproteins and tissue fatty acid composition in humans. | 2001 | Lipids | pmid:11337977 |
| Molina MT et al. | Caecal and colonic uptake of both linoleic acid and cholesterol in rats following intestinal resection. | 1990 | Lipids | pmid:2079865 |
| Kanner J and Kinsella JE | Initiation of lipid peroxidation by a peroxidase/hydrogen peroxide/halide system. | 1983 | Lipids | pmid:6855480 |
| Sehat N et al. | Identification of conjugated linoleic acid isomers in cheese by gas chromatography, silver ion high performance liquid chromatography and mass spectral reconstructed ion profiles. Comparison of chromatographic elution sequences. | 1998 | Lipids | pmid:9832075 |