Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Liver Diseases D008107 31 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liposarcoma D008080 1 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Leukemia D007938 74 associated lipids
Leptospirosis D007922 2 associated lipids
Lactose Intolerance D007787 2 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Kidney Diseases D007674 29 associated lipids
Darier Disease D007644 2 associated lipids
Keloid D007627 12 associated lipids
Insulin Resistance D007333 99 associated lipids
Inflammation D007249 119 associated lipids
Infertility, Male D007248 11 associated lipids
Infertility D007246 3 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Hypertension, Renal D006977 9 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Hypertension D006973 115 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Hyperplasia D006965 34 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hepatolenticular Degeneration D006527 3 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Hemolysis D006461 131 associated lipids
Heart Failure D006333 36 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Haemophilus Infections D006192 3 associated lipids
Glomerulonephritis D005921 35 associated lipids
Glioma D005910 112 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Gastritis D005756 27 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Fatty Liver, Alcoholic D005235 11 associated lipids
Fatty Liver D005234 48 associated lipids
Fat Necrosis D005218 1 associated lipids
Facial Nerve Diseases D005155 1 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Enuresis D004775 1 associated lipids
Encopresis D004688 1 associated lipids
Embolism, Fat D004620 4 associated lipids
Edema D004487 152 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Otsuka H et al. [Studies on anti-inflammatory agents. IV. Anti-inflammatory constituents from roots of Panax ginseng C.A. Meyer (author's transl)]. 1981 Yakugaku Zasshi pmid:7338798
Osaki Y et al. [Antimutagenic and bactericidal substances in the fruit body of a Basidiomycete Agaricus blazei, Jun-17]. 1994 Yakugaku Zasshi pmid:8014843
Toda S et al. [Inhibitory effects of methanol extracts of crude drugs on the air oxidation of linoleic acid]. 1984 Yakugaku Zasshi pmid:6491877
Okuyama H [Need to change the direction of cholesterol-related medication--a problem of great urgency]. 2005 Yakugaku Zasshi pmid:16272805
Byczkowski JZ and Kulkarni AP Linoleate-dependent co-oxygenation of benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol by rat cytosolic lipoxygenase. 1992 Xenobiotica pmid:1413876
Cardoso CR et al. Influence of topical administration of n-3 and n-6 essential and n-9 nonessential fatty acids on the healing of cutaneous wounds. 2004 Mar-Apr Wound Repair Regen pmid:15086775
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Okuyama H et al. Omega3 fatty acids effectively prevent coronary heart disease and other late-onset diseases--the excessive linoleic acid syndrome. 2007 World Rev Nutr Diet pmid:17167282
Okuyama H et al. Why isn't the causal relationship between linoleic acid and mortalities from coronary heart disease and stroke revealed by clinical studies? 2007 World Rev Nutr Diet pmid:17167283
Okuyama H et al. Mechanisms by which dietary fats affect coronary heart disease mortality. 2007 World Rev Nutr Diet pmid:17167284
Okuyama H et al. Cancers common in the USA are stimulated by omega 6 fatty acids and large amounts of animal fats, but suppressed by omega 3 fatty acids and cholesterol. 2007 World Rev Nutr Diet pmid:17167285
Demmelmair H et al. Polyunsaturated fatty acid metabolism during lactation. 2001 World Rev Nutr Diet pmid:11935954
Sugano M Isomeric fatty acids: their physiological significance and health implications. 2001 World Rev Nutr Diet pmid:11935963
Okuyama H and Sakai K Effects of dietary oils with extreme omega 3/omega 6 ratios--selective incorporation and differential catabolism. 1991 World Rev Nutr Diet pmid:1675826