Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Huang X et al. | Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: a novel therapeutic strategy in acute myeloid leukemia. | 2013 | Clin. Cancer Res. | pmid:23493348 |
Chukir T et al. | Shared retronasal identifications of vapor-phase 18-carbon fatty acids. | 2013 | Chem. Senses | pmid:23424022 |
Anton SD et al. | Differential effects of adulterated versus unadulterated forms of linoleic acid on cardiovascular health. | 2013 | J Integr Med | pmid:23464640 |
Zhang J et al. | Characteristics of fatty acid distribution is associated with colorectal cancer prognosis. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23465412 |
Moon C et al. | Modeling sulfate removal by inhibited mesophilic mixed anaerobic communities using a statistical approach. | 2013 | Water Res. | pmid:23466036 |
Sy C et al. | Inhibition of iron-induced lipid peroxidation by newly identified bacterial carotenoids in model gastric conditions: comparison with common carotenoids. | 2013 | Food Funct | pmid:23411789 |
Salama el-S et al. | Biomass, lipid content, and fatty acid composition of freshwater Chlamydomonas mexicana and Scenedesmus obliquus grown under salt stress. | 2013 | Bioprocess Biosyst Eng | pmid:23411874 |
Tarawneh AH et al. | Fatty acids with in vitro binding affinity for human opioid receptors from the fungus Emericella nidulans. | 2013 | J. Agric. Food Chem. | pmid:24147790 |
Bae WK et al. | Docetaxel-loaded thermoresponsive conjugated linoleic acid-incorporated poloxamer hydrogel for the suppression of peritoneal metastasis of gastric cancer. | 2013 | Biomaterials | pmid:23174142 |
Lin KH et al. | Antioxidant activity of herbaceous plant extracts protect against hydrogen peroxide-induced DNA damage in human lymphocytes. | 2013 | BMC Res Notes | pmid:24279749 |
Klein-Wieringa IR et al. | Adipocytes modulate the phenotype of human macrophages through secreted lipids. | 2013 | J. Immunol. | pmid:23817431 |
Wei J et al. | Linoleic acid attenuates endothelium-derived relaxing factor production by suppressing cAMP-hydrolyzing phosphodiesterase activity. | 2013 | Circ. J. | pmid:23883876 |
Moloney AP et al. | Colour of fat, and colour, fatty acid composition and sensory characteristics of muscle from heifers offered alternative forages to grass silage in a finishing ration. | 2013 | Meat Sci. | pmid:23806853 |
Lagarde M et al. | Lipidomics of essential fatty acids and oxygenated metabolites. | 2013 | Mol Nutr Food Res | pmid:23818385 |
Falavigna C et al. | Fatty acid esters of fumonisins: first evidence of their presence in maize. | 2013 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:23819788 |
Zhao X et al. | Analysis of fatty acids and phytosterols in ethanol extracts of Nelumbo nucifera seeds and rhizomes by GC-MS. | 2013 | J. Agric. Food Chem. | pmid:23742045 |
Kikalishvili BIu et al. | [The fatty acid composition of peach oil and its biological activity]. | 2013 | Georgian Med News | pmid:23787514 |
Renner L et al. | Effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid, linoleic acid, phytanic acid and the combination of various fatty acids on proliferation and cytokine expression of bovine peripheral blood mononuclear cells. | 2013 | Nutrients | pmid:23857174 |
Li A et al. | Thermally induced isomerization of linoleic acid in soybean oil. | 2013 | Chem. Phys. Lipids | pmid:23261796 |
Mena J et al. | Linoleic acid increases adhesion, chemotaxis, granule release, intracellular calcium mobilisation, MAPK phosphorylation and gene expression in bovine neutrophils. | 2013 | Vet. Immunol. Immunopathol. | pmid:23267746 |
Li L et al. | A novel galanin receptor 1a gene in zebrafish: tissue distribution, developmental expression roles in nutrition regulation. | 2013 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:23268327 |
Zeng G et al. | Kinetics of heterogeneous reaction of ozone with linoleic acid and its dependence on temperature, physical state, RH, and ozone concentration. | 2013 | J Phys Chem A | pmid:23347186 |
Raatz SK et al. | Dose-dependent consumption of farmed Atlantic salmon (Salmo salar) increases plasma phospholipid n-3 fatty acids differentially. | 2013 | J Acad Nutr Diet | pmid:23351633 |
Lohner S et al. | Gender differences in the long-chain polyunsaturated fatty acid status: systematic review of 51 publications. | 2013 | Ann. Nutr. Metab. | pmid:23327902 |
MacIntosh BA et al. | Low-n-6 and low-n-6 plus high-n-3 diets for use in clinical research. | 2013 | Br. J. Nutr. | pmid:23328113 |
Soto-Guzman A et al. | Role of arachidonic acid metabolism in Stat5 activation induced by oleic acid in MDA-MB-231 breast cancer cells. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23332799 |
Poudyal H et al. | Responses to oleic, linoleic and α-linolenic acids in high-carbohydrate, high-fat diet-induced metabolic syndrome in rats. | 2013 | J. Nutr. Biochem. | pmid:23333092 |
Zamora-Rojas E et al. | Prediction of fatty acids content in pig adipose tissue by near infrared spectroscopy: at-line versus in-situ analysis. | 2013 | Meat Sci. | pmid:23793086 |
Chiou TY et al. | Characteristics and antioxidative ability of defatted rice bran extracts obtained using several extractants under subcritical conditions. | 2013 | J Oleo Sci | pmid:23357811 |
Fijlstra M et al. | Reduced absorption of long-chain fatty acids during methotrexate-induced gastrointestinal mucositis in the rat. | 2013 | Clin Nutr | pmid:23102689 |
Zlatanov MD et al. | Lipid composition of Castanea sativa Mill. and Aesculus hippocastanum fruit oils. | 2013 | J. Sci. Food Agric. | pmid:23174908 |
Ali Q et al. | Ameliorating effects of exogenously applied proline on seed composition, seed oil quality and oil antioxidant activity of maize (Zea mays L.) under drought stress. | 2013 | Int J Mol Sci | pmid:23344043 |
Ogata F et al. | Study on analysis of waste edible oil with deterioration and removal of acid value, carbonyl value, and free fatty acid by a food additive (calcium silicate). | 2013 | J Oleo Sci | pmid:23391535 |
Loizzo MR et al. | Phenolics, aroma profile, and in vitro antioxidant activity of Italian dessert passito wine from Saracena (Italy). | 2013 | J. Food Sci. | pmid:23574495 |
Bassett JK et al. | Plasma phospholipid fatty acids, dietary fatty acids and prostate cancer risk. | 2013 | Int. J. Cancer | pmid:23575905 |
Brouwer IA et al. | Trans fatty acids and cardiovascular health: research completed? | 2013 | Eur J Clin Nutr | pmid:23531781 |
Mujtaba SF et al. | Singlet oxygen mediated apoptosis by anthrone involving lysosomes and mitochondria at ambient UV exposure. | 2013 | J. Hazard. Mater. | pmid:23542321 |
Wardhani DH et al. | Inhibition kinetics of lipid oxidation of model foods by using antioxidant extract of fermented soybeans. | 2013 | Food Chem | pmid:23561179 |
Garofalo JM et al. | Mouse mammary gland is refractory to the effects of ethanol after natural lactation. | 2013 | Comp. Med. | pmid:23561936 |
Hein LK et al. | Selective reduction of bis(monoacylglycero)phosphate ameliorates the storage burden in a THP-1 macrophage model of Gaucher disease. | 2013 | J. Lipid Res. | pmid:23564732 |
Zhao Y et al. | Linoleic acid stimulates [Ca2+]i increase in rat pancreatic beta-cells through both membrane receptor- and intracellular metabolite-mediated pathways. | 2013 | PLoS ONE | pmid:23565210 |
Bakır T et al. | Polar paradox revisited: analogous pairs of hydrophilic and lipophilic antioxidants in linoleic acid emulsion containing Cu(II). | 2013 | J. Sci. Food Agric. | pmid:23520052 |
Abdoul-Azize S et al. | Oro-gustatory perception of dietary lipids and calcium signaling in taste bud cells are altered in nutritionally obesity-prone Psammomys obesus. | 2013 | PLoS ONE | pmid:23936306 |
Adachi S et al. | Increased levels of extracellular dopamine in the nucleus accumbens and amygdala of rats by ingesting a low concentration of a long-chain Fatty Acid. | 2013 | Biosci. Biotechnol. Biochem. | pmid:24200795 |
Kummerow FA et al. | Effects of trans fats on prostacyclin production. | 2013 | Scand. Cardiovasc. J. | pmid:24228623 |
Vasudevan C et al. | The effect of parenteral lipid emulsions on pulmonary hemodynamics and eicosanoid metabolites in preterm infants: a pilot study. | 2013 | Nutr Clin Pract | pmid:24177284 |
Smink W et al. | Effect of intake of linoleic acid and α-linolenic acid levels on conversion into long-chain polyunsaturated fatty acids in backfat and in intramuscular fat of growing pigs. | 2013 | J Anim Physiol Anim Nutr (Berl) | pmid:22463497 |
Gibson RA et al. | Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22515943 |
Benbrook CM et al. | Organic production enhances milk nutritional quality by shifting fatty acid composition: a United States-wide, 18-month study. | 2013 | PLoS ONE | pmid:24349282 |
Green DP et al. | Role of endogenous TRPV1 agonists in a postburn pain model of partial-thickness injury. | 2013 | Pain | pmid:23891895 |
Steffen BT et al. | n-3 and n-6 Fatty acids are independently associated with lipoprotein-associated phospholipase A2 in the Multi-Ethnic Study of Atherosclerosis. | 2013 | Br. J. Nutr. | pmid:23551952 |
Ruparel S et al. | Oxidized linoleic acid metabolite-cytochrome P450 system (OLAM-CYP) is active in biopsy samples from patients with inflammatory dental pain. | 2013 | Pain | pmid:23867730 |
Yang Y and McClements DJ | Vitamin E and vitamin E acetate solubilization in mixed micelles: physicochemical basis of bioaccessibility. | 2013 | J Colloid Interface Sci | pmid:23768725 |
Del Mar Bibiloni M et al. | Dietary factors associated with subclinical inflammation among girls. | 2013 | Eur J Clin Nutr | pmid:24149444 |
Vukašinović EL et al. | Diapause induces changes in the composition and biophysical properties of lipids in larvae of the European corn borer, Ostrinia nubilalis (Lepidoptera: Crambidae). | 2013 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:23701990 |
Layek B and Singh J | Cell penetrating peptide conjugated polymeric micelles as a high performance versatile nonviral gene carrier. | 2013 | Biomacromolecules | pmid:24083483 |
Luo X et al. | Comparison of enzymatic activity of two linoleic acid isomerases expressed in E. coli. | 2013 | Mol. Biol. Rep. | pmid:24062071 |
Peters BD et al. | Polyunsaturated fatty acid concentration predicts myelin integrity in early-phase psychosis. | 2013 | Schizophr Bull | pmid:22927668 |
Ramsden CE et al. | Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans. | 2012 Oct-Nov | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22959954 |
Mysiakina IS et al. | [Lipid composition of fungus Mucor hiemalis mycelium grown in the presence of trehalose, triacylglycerols, and itraconazole]. | 2012 Nov-Dec | Mikrobiologiia | pmid:23610922 |
Mysiakina IS et al. | [Effect of biological factors on morphogenesis, growth, and lipid composition of fungus Mucor hiemalis mycelium]. | 2012 Nov-Dec | Mikrobiologiia | pmid:23610923 |
Alinezhad H et al. | Biochemical activities of acetone extracts of Hyssopus angustifolius. | 2012 Jul-Aug | Acta Pol Pharm | pmid:22876603 |
Moghaddam AH et al. | Antioxidant, antihemolytic and nephroprotective activity of aqueous extract of Diospyros lotus seeds. | 2012 Jul-Aug | Acta Pol Pharm | pmid:22876611 |
Kuipers RS et al. | Fetal intrauterine whole body linoleic, arachidonic and docosahexaenoic acid contents and accretion rates. | 2012 Jan-Feb | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22115845 |
Brenna T | Tissue-specific LCPUFA accretion in fetal humans. | 2012 Jan-Feb | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22078006 |
Chivandi E et al. | Suppression of Caco-2 and HEK-293 cell proliferation by Kigelia africana, Mimusops zeyheri and Ximenia caffra seed oils. | 2012 Jan-Feb | In Vivo | pmid:22210722 |
Salleh WM et al. | Chemical compositions, antioxidant and antimicrobial activity of the essential oils of Piper officinarum (Piperaceae). | 2012 | Nat Prod Commun | pmid:23413576 |
Moodley R et al. | Elemental composition and fatty acid profile of the edible fruits of Amatungula (Carissa macrocarpa) and impact of soil quality on chemical characteristics. | 2012 | Anal. Chim. Acta | pmid:22632042 |
Ruparel S et al. | Plasticity of cytochrome P450 isozyme expression in rat trigeminal ganglia neurons during inflammation. | 2012 | Pain | pmid:22633978 |
Jarret RL and Levy IJ | Oil and fatty acid contents in seed of Citrullus lanatus Schrad. | 2012 | J. Agric. Food Chem. | pmid:22540530 |
Shimomura K et al. | Identification of the plant origin of propolis from Jeju Island, Korea, by observation of honeybee behavior and phytochemical analysis. | 2012 | Biosci. Biotechnol. Biochem. | pmid:23132582 |
Dramane G et al. | STIM1 regulates calcium signaling in taste bud cells and preference for fat in mice. | 2012 | J. Clin. Invest. | pmid:22546859 |
Kurotani K et al. | High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance. | 2012 | Nutr Res | pmid:23084639 |
Trevizan L et al. | Maintenance of arachidonic acid and evidence of Δ5 desaturation in cats fed γ-linolenic and linoleic acid enriched diets. | 2012 | Lipids | pmid:22249937 |
Georgiadi A et al. | Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart. | 2012 | Physiol. Genomics | pmid:22274564 |
Alvheim AR et al. | Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity. | 2012 | Obesity (Silver Spring) | pmid:22334255 |
Weiss LA et al. | The omega-6 fatty acid linoleic acid is associated with risk of gastroschisis: a novel dietary risk factor. | 2012 | Am. J. Med. Genet. A | pmid:22315197 |
Sun X et al. | Lipid peroxidation and DNA adduct formation in lymphocytes of premenopausal women: Role of estrogen metabolites and fatty acid intake. | 2012 | Int. J. Cancer | pmid:22322480 |
Zhu X et al. | Release property and antioxidant effectiveness of tocopherol-incorporated LDPE/PP blend films. | 2012 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:22257167 |
Rodrigues HG et al. | Oral administration of oleic or linoleic acid accelerates the inflammatory phase of wound healing. | 2012 | J. Invest. Dermatol. | pmid:21881592 |
de Batlle J et al. | Association between Ω3 and Ω6 fatty acid intakes and serum inflammatory markers in COPD. | 2012 | J. Nutr. Biochem. | pmid:21889886 |
Koch C et al. | Linoleic acid positioning in psi factor producing oxygenase A, a fusion protein with an atypical cytochrome P450 activity. | 2012 | FEBS J. | pmid:21920024 |
Burstein S et al. | N-Amino acid linoleoyl conjugates: anti-inflammatory activities. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22217875 |
Cheguru P et al. | Adipocyte differentiation-specific gene transcriptional response to C18 unsaturated fatty acids plus insulin. | 2012 | Pflugers Arch. | pmid:22218833 |
Mormile R et al. | Linoleic acid and colorectal cancer cell growth suppression: is the deregulation of mitochondrial survivin the key factor? | 2012 | Int J Colorectal Dis | pmid:22231621 |
Luévano-MartÃnez LA et al. | A critical tyrosine residue determines the uncoupling protein-like activity of the yeast mitochondrial oxaloacetate carrier. | 2012 | Biochem. J. | pmid:22236206 |
Takahashi T et al. | Effect of linoleic acid albumin in a dilution solution and long-term equilibration for freezing of bovine spermatozoa with poor freezability. | 2012 | Reprod. Domest. Anim. | pmid:21635578 |
Kowalska A et al. | Impact of diets with different proportions of linseed and sunflower oils on the growth, liver histology, immunological and chemical blood parameters, and proximate composition of pikeperch Sander lucioperca (L.). | 2012 | Fish Physiol. Biochem. | pmid:21656178 |
Romano R et al. | Comparison of the frying performance of olive oil and palm superolein. | 2012 | J. Food Sci. | pmid:22490166 |
Manosroi A et al. | Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction. | 2012 | Eur J Pharm Biopharm | pmid:22490981 |
Smink W et al. | Linoleic and α-linolenic acid as precursor and inhibitor for the synthesis of long-chain polyunsaturated fatty acids in liver and brain of growing pigs. | 2012 | Animal | pmid:22436184 |
Zened A et al. | In vitro study of dietary factors affecting the biohydrogenation shift from trans-11 to trans-10 fatty acids in the rumen of dairy cows. | 2012 | Animal | pmid:22436225 |
Liu X et al. | Method for screening of bacterial strains biosynthesizing specific conjugated linoleic acid isomers. | 2012 | J. Agric. Food Chem. | pmid:22946615 |
Steffen BT et al. | Obesity modifies the association between plasma phospholipid polyunsaturated fatty acids and markers of inflammation: the Multi-Ethnic Study of Atherosclerosis. | 2012 | Int J Obes (Lond) | pmid:21829163 |
Khan R et al. | Variation in oil content and fatty acid composition of the seed oil of Acacia species collected from the northwest zone of India. | 2012 | J. Sci. Food Agric. | pmid:22351513 |
Chen MH and Nelson EB | Microbial-induced carbon competition in the spermosphere leads to pathogen and disease suppression in a municipal biosolids compost. | 2012 | Phytopathology | pmid:22352306 |
Novak EM et al. | Low linoleic acid may facilitate Δ6 desaturase activity and docosahexaenoic acid accretion in human fetal development. | 2012 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:22365109 |
He M et al. | Effect of dietary fat blend enriched in oleic or linoleic acid and monensin supplementation on dairy cattle performance, milk fatty acid profiles, and milk fat depression. | 2012 | J. Dairy Sci. | pmid:22365227 |
Castro LF et al. | Functional desaturase Fads1 (Δ5) and Fads2 (Δ6) orthologues evolved before the origin of jawed vertebrates. | 2012 | PLoS ONE | pmid:22384110 |
Li KL et al. | Characterization of cumulus expansion-inhibiting factor (CEIF) in goat follicles. | 2012 | Biol. Reprod. | pmid:22402961 |