Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Yavin E and Green P | Distribution, processing and selective esterification of essential fatty acid metabolites in the fetal brain. | 1994 | World Rev Nutr Diet | pmid:7871815 |
Lien EL | The ratio of linoleic acid to alpha-linolenic acid in infant formulas: current facts and future research directions. | 1994 | World Rev Nutr Diet | pmid:7871839 |
Ramsden CE et al. | All PUFAs are not created equal: absence of CHD benefit specific to linoleic acid in randomized controlled trials and prospective observational cohorts. | 2011 | World Rev Nutr Diet | pmid:21865817 |
Watkins BA et al. | Designed eggs containing conjugated linoleic acids and omega-3 polyunsaturated fatty acids. | 2001 | World Rev Nutr Diet | pmid:11545041 |
Holman RT | Highpoints in an affair with polyunsaturated fatty acids. | 1991 | World Rev Nutr Diet | pmid:2053355 |
Bibus DM and Stitt PA | Metabolism of alpha-linolenic acid from flaxseed in dogs. | 1998 | World Rev Nutr Diet | pmid:9648515 |
Okuyama H et al. | Omega3 fatty acids effectively prevent coronary heart disease and other late-onset diseases--the excessive linoleic acid syndrome. | 2007 | World Rev Nutr Diet | pmid:17167282 |
Okuyama H et al. | Why isn't the causal relationship between linoleic acid and mortalities from coronary heart disease and stroke revealed by clinical studies? | 2007 | World Rev Nutr Diet | pmid:17167283 |
Okuyama H et al. | Mechanisms by which dietary fats affect coronary heart disease mortality. | 2007 | World Rev Nutr Diet | pmid:17167284 |
Okuyama H et al. | Cancers common in the USA are stimulated by omega 6 fatty acids and large amounts of animal fats, but suppressed by omega 3 fatty acids and cholesterol. | 2007 | World Rev Nutr Diet | pmid:17167285 |