Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Charnock JS | Gamma-linolenic acid provides additional protection against ventricular fibrillation in aged rats fed linoleic acid rich diets. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780878 |
Smith DE and Salerno JW | Selective growth inhibition of a human malignant melanoma cell line by sesame oil in vitro. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1502251 |
Glew RH et al. | Fatty acid composition of the milk lipids of Nepalese women: correlation between fatty acid composition of serum phospholipids and melting point. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728165 |
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Bell JG et al. | Effects of increasing dietary linoleic acid on phospholipid fatty acid composition and eicosanoid production in leucocytes and gill cells of Atlantic salmon (Salmo salar). | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1589446 |
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Kritchevsky D | Trans fatty acids and cardiovascular risk. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9430386 |
Renaud SC | Dietary management of cardiovascular diseases. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9430390 |
Vaddadi KS | The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. | 1981 | Prostaglandins Med | pmid:6269135 |
Zabielski P et al. | The effect of high-fat diet on the sphingolipid pathway of signal transduction in regenerating rat liver. | 2010 | Prostaglandins Other Lipid Mediat. | pmid:20599517 |