Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Banni S et al. | An increase in vitamin A status by the feeding of conjugated linoleic acid. | 1999 | Nutr Cancer | pmid:10227044 |
Cortez-Pinto H et al. | Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes. | 1999 | Gastroenterology | pmid:10220511 |
Juanéda P and Sébédio JL | Combined silver-ion and reversed-phase high-performance liquid chromatography for the separation and identification of C20 metabolites of conjugated linoleic acid isomers in rat liver lipids. | 1999 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10219661 |
Minich DM et al. | Bile diversion in rats leads to a decreased plasma concentration of linoleic acid which is not due to decreased net intestinal absorption of dietary linoleic acid. | 1999 | Biochim. Biophys. Acta | pmid:10216285 |
Spaide RF et al. | Characterization of peroxidized lipids in Bruch's membrane. | 1999 | Retina (Philadelphia, Pa.) | pmid:10213241 |
Bergamini S et al. | Prooxidant activity of ferrioxamine in isolated rat hepatocytes and linoleic acid micelles. | 1999 | Chem. Res. Toxicol. | pmid:10207126 |
Hennig B et al. | Antioxidant-like properties of zinc in activated endothelial cells. | 1999 | J Am Coll Nutr | pmid:10204831 |
DeLany JP et al. | Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake. | 1999 | Am. J. Physiol. | pmid:10198400 |
Jayawickreme SP et al. | Regulation of 15-lipoxygenase expression and mucus secretion by IL-4 in human bronchial epithelial cells. | 1999 | Am. J. Physiol. | pmid:10198357 |
Augé N et al. | Uptake of 13-hydroperoxylinoleic acid by cultured cells. | 1999 | Arterioscler. Thromb. Vasc. Biol. | pmid:10195919 |