Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Infertility, Male D007248 11 associated lipids
Varicocele D014646 4 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Rum P and Hornstra G The n-3 and n-6 polyunsaturated fatty acid composition of plasma phospholipids in pregnant women and their infants. relationship with maternal linoleic acid intake. 2002 Clin. Chem. Lab. Med. pmid:11916268
Hatano T et al. Proanthocyanidin glycosides and related polyphenols from cacao liquor and their antioxidant effects. 2002 Phytochemistry pmid:11909632
Masters N et al. Maternal supplementation with CLA decreases milk fat in humans. 2002 Lipids pmid:11908905
Rong R et al. Dietary oxidized fatty acids may enhance intestinal apolipoprotein A-I production. 2002 J. Lipid Res. pmid:11907138
Hurtado de Catalfo GE and de Gomez Dumm IN Polyunsaturated fatty acid biosynthesis from [1-14C]20:3 n-6 acid in rat cultured Sertoli cells. Linoleic acid effect. 2002 Int. J. Biochem. Cell Biol. pmid:11906823
Nakaya A et al. Helicobacter pylori alters n-6 fatty acid metabolism and prostaglandin E2 synthesis in rat gastric mucosal cells. 2001 J. Gastroenterol. Hepatol. pmid:11903735
Kikuzaki H et al. Antioxidant properties of ferulic acid and its related compounds. 2002 J. Agric. Food Chem. pmid:11902973
Galindo-Cuspinera V et al. Comparison of volatile compounds in water- and oil-soluble annatto (Bixa orellana L.) extracts. 2002 J. Agric. Food Chem. pmid:11902949
Du M and Ahn DU Effect of dietary conjugated linoleic acid on the growth rate of live birds and on the abdominal fat content and quality of broiler meat. 2002 Poult. Sci. pmid:11902422
King LM et al. Cloning of CYP2J2 gene and identification of functional polymorphisms. 2002 Mol. Pharmacol. pmid:11901223
Pan J and Chung FL Formation of cyclic deoxyguanosine adducts from omega-3 and omega-6 polyunsaturated fatty acids under oxidative conditions. 2002 Chem. Res. Toxicol. pmid:11896684
Whigham LD et al. Decreased antigen-induced eicosanoid release in conjugated linoleic acid-fed guinea pigs. 2002 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:11893615
Roberts DC Nutrition and metabolism. 2002 Curr. Opin. Lipidol. pmid:11891423
Kawai T et al. Troglitazone ameliorates lipotoxicity in the beta cell line INS-1 expressing PPAR gamma. 2002 Diabetes Res. Clin. Pract. pmid:11891015
Yang H et al. Effect of conjugated linoleic acid on the formation of spontaneous and PhIP-induced mutation in the colon and cecum of rats. 2002 Mutat. Res. pmid:11890945
Beaulieu AD et al. Concentrations of conjugated linoleic acid (cis-9, trans-11-octadecadienoic acid) are not increased in tissue lipids of cattle fed a high-concentrate diet supplemented with soybean oil. 2002 J. Anim. Sci. pmid:11890424
Wiegand BR et al. Duration of feeding conjugated linoleic acid influences growth performance, carcass traits, and meat quality of finishing barrows. 2002 J. Anim. Sci. pmid:11890399
Bolte MR et al. Feeding lambs high-oleate or high-linoleate safflower seeds differentially influences carcass fatty acid composition. 2002 J. Anim. Sci. pmid:11890397
Dichtl W et al. Linoleic acid-stimulated vascular adhesion molecule-1 expression in endothelial cells depends on nuclear factor-kappaB activation. 2002 Metab. Clin. Exp. pmid:11887169
Svahn JC et al. Different quantities and quality of fat in milk products given to young children: effects on long chain polyunsaturated fatty acids and trans fatty acids in plasma. 2002 Acta Paediatr. pmid:11885548
Evans M et al. Trans-10, cis-12 conjugated linoleic acid increases fatty acid oxidation in 3T3-L1 preadipocytes. 2002 J. Nutr. pmid:11880570
Urquhart P et al. The effect of conjugated linoleic acid on arachidonic acid metabolism and eicosanoid production in human saphenous vein endothelial cells. 2002 Biochim. Biophys. Acta pmid:11880240
Jardine D et al. Liquid chromatography-mass spectrometry (LC-MS) investigation of the thiobarbituric acid reactive substances (TBARS) reaction. 2002 J. Agric. Food Chem. pmid:11879064
Inouye K et al. Deodorization of soybean proteins by enzymatic and physicochemical treatments. 2002 J. Agric. Food Chem. pmid:11879052
Elabbadi N et al. Regulation of phosphatidic acid phosphohydrolase 1 by fatty acids. 2002 Lipids pmid:11876265
van Dam RM et al. Dietary fat and meat intake in relation to risk of type 2 diabetes in men. 2002 Diabetes Care pmid:11874924
Sakurai T et al. Short-term efficacy of enteral nutrition in the treatment of active Crohn's disease: a randomized, controlled trial comparing nutrient formulas. 2002 Mar-Apr JPEN J Parenter Enteral Nutr pmid:11871742
Futakuchi M et al. Inhibition of conjugated fatty acids derived from safflower or perilla oil of induction and development of mammary tumors in rats induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). 2002 Cancer Lett. pmid:11867197
Ishido E et al. Kinetic expression for the oxidation of linoleic and arachidonic acid esters in their mixed system. 2002 Biosci. Biotechnol. Biochem. pmid:11866122
Lichtenstein AH et al. Efficacy of a Therapeutic Lifestyle Change/Step 2 diet in moderately hypercholesterolemic middle-aged and elderly female and male subjects. 2002 J. Lipid Res. pmid:11861668
Zhu Y et al. [The inhibitory effect of CLA on mice forestomach neoplasia induced by B(a)P]. 2001 Zhonghua Yu Fang Yi Xue Za Zhi pmid:11860953
Whitlock LA et al. Fish oil and extruded soybeans fed in combination increase conjugated linoleic acids in milk of dairy cows more than when fed separately. 2002 J. Dairy Sci. pmid:11860116
Demcakova E et al. Delta-6 desaturase activity and gene expression, tissue fatty acid profile and glucose turnover rate in hereditary hypertriglyceridemic rats. 2001 Endocr Regul pmid:11858764
Kohno H et al. Dietary conjugated linolenic acid inhibits azoxymethane-induced colonic aberrant crypt foci in rats. 2002 Jpn. J. Cancer Res. pmid:11856476
Reyes-De-Corcuera JI et al. Improved amperometric method for the rapid and quantitative measurement of lipoxygenase activity in vegetable tissue crude homogenates. 2002 J. Agric. Food Chem. pmid:11853470
Pappas A et al. Metabolic fate and selective utilization of major fatty acids in human sebaceous gland. 2002 J. Invest. Dermatol. pmid:11851890
Sheu MY et al. Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models. 2002 J. Invest. Dermatol. pmid:11851881
Papanikolaou S and Aggelis G Lipid production by Yarrowia lipolytica growing on industrial glycerol in a single-stage continuous culture. 2002 Bioresour. Technol. pmid:11848376
Hernández A et al. In vivo activation of plasma membrane H(+)-ATPase hydrolytic activity by complex lipid-bound unsaturated fatty acids in Ustilago maydis. 2002 Eur. J. Biochem. pmid:11846803
Napolitano A et al. Reactions of hydro(pero)xy derivatives of polyunsaturated fatty acids/esters with nitrite ions under acidic conditions. Unusual nitrosative breakdown of methyl 13-hydro(pero)xyoctadeca-9,11-dienoate to a novel 4-nitro-2-oximinoalk-3-enal product. 2002 J. Org. Chem. pmid:11846653
Calder PC Conjugated linoleic acid in humans--reasons to be cheerful? 2002 Curr Opin Clin Nutr Metab Care pmid:11844976
Ramirez DC and Gimenez MS Lipid modification in mouse peritoneal macrophages after chronic cadmium exposure. 2002 Toxicology pmid:11844611
Cahoon EB et al. Transgenic production of epoxy fatty acids by expression of a cytochrome P450 enzyme from Euphorbia lagascae seed. 2002 Plant Physiol. pmid:11842164
Krutetskaia ZI et al. [Effect of arachidonic and other fatty acids on the intracellular calcium concentration and calcium signaling in peritoneal macrophages]. 2001 Tsitologiia pmid:11840781
Lemaitre RN et al. Cell membrane trans-fatty acids and the risk of primary cardiac arrest. 2002 Circulation pmid:11839624
Minemoto Y et al. Oxidation of linoleic acid encapsulated with gum arabic or maltodextrin by spray-drying. 2002 Mar-Apr J Microencapsul pmid:11837973
Joo ST et al. Effects of dietary conjugated linoleic acid on fatty acid composition, lipid oxidation, color, and water-holding capacity of pork loin. 2002 J. Anim. Sci. pmid:11831506
Baron CP et al. Concentration effects in myoglobin-catalyzed peroxidation of linoleate. 2002 J. Agric. Food Chem. pmid:11829662
Raes K et al. The deposition of conjugated linoleic acids in eggs of laying hens fed diets varying in fat level and fatty acid profile. 2002 J. Nutr. pmid:11823576
Mitchell LA et al. Linoleic acid, cis-epoxyoctadecenoic acids, and dihydroxyoctadecadienoic acids are toxic to Sf-21 cells in the absence of albumin. 2002 Toxicol. Lett. pmid:11814707
Kawajiri H et al. Arachidonic and linoleic acid metabolism in mouse intestinal tissue: evidence for novel lipoxygenase activity. 2002 Arch. Biochem. Biophys. pmid:11811948
Ulusu NN et al. Abietic acid inhibits lipoxygenase activity. 2002 Phytother Res pmid:11807975
McCarthy-Beckett DO Dietary supplementation with conjugated linoleic acid does not improve nutritional status of tumor-bearing rats. 2002 Res Nurs Health pmid:11807919
Wang CT et al. A calcium-independent phospholipase activity insensitive to bromoenol lactone mediates arachidonic acid release by lindane in rat myometrial cells. 2001 Life Sci. pmid:11798014
Vargas F et al. In vitro antioxidant and photo-oxidant properties of dipyridamole. 2001 Nov-Dec Int. J. Toxicol. pmid:11797818
Milne GL and Porter NA Separation and identification of phospholipid peroxidation products. 2001 Lipids pmid:11795860
Schäfer K et al. Incorporation of dietary linoleic and conjugated linoleic acids and related effects on eggs of laying hens. 2001 Lipids pmid:11795854
Duffin KL et al. Lipid remodeling in mouse liver and plasma resulting from delta6 fatty acid desaturase inhibition. 2001 Lipids pmid:11795852
Azulay JP and Pouget J [Diabetic neuropathies]. 2001 Rev Prat pmid:11795122
Gwak HS and Chun IK Effect of vehicles and enhancers on the in vitro skin penetration of aspalatone and its enzymatic degradation across rat skins. 2001 Arch. Pharm. Res. pmid:11794538
Fidler N et al. Fat content and fatty acid composition of fresh, pasteurized, or sterilized human milk. 2001 Adv. Exp. Med. Biol. pmid:11787720
Demmelmair H et al. Investigation of long-chain polyunsaturated fatty acid metabolism in lactating women by means of stable isotope techniques. 2001 Adv. Exp. Med. Biol. pmid:11787680
Agostoni C et al. Long-chain polyunsaturated fatty acid concentrations in human hindmilk are constant throughout twelve months of lactation. 2001 Adv. Exp. Med. Biol. pmid:11787678
De Vriese SR et al. Estimation of dietary fat intake of Belgian pregnant women. Comparison of two methods. 2001 Ann. Nutr. Metab. pmid:11786650
Birnbaum L Addition of conjugated linoleic acid to a herbal anticellulite pill. 2001 Sep-Oct Adv Ther pmid:11783459
Tripathi AK et al. A physiochemical mechanism of hemozoin (beta-hematin) synthesis by malaria parasite. 2002 Biochem. Biophys. Res. Commun. pmid:11779214
Olson RE The key to an enigma: how do dietary polyunsaturated fatty acids lower serum cholesterol? 2002 J. Nutr. pmid:11773520
Miller A et al. Modulation of arachidonic acid distribution by conjugated linoleic acid isomers and linoleic acid in MCF-7 and SW480 cancer cells. 2001 Lipids pmid:11768161
Chuang LT et al. Inhibitory effect of conjugated linoleic acid on linoleic acid elongation in transformed yeast with human elongase. 2001 Lipids pmid:11768153
Eggert JM et al. Effects of conjugated linoleic acid on the belly firmness and fatty acid composition of genetically lean pigs. 2001 J. Anim. Sci. pmid:11768116
Matsingou TC et al. Aqueous infusions of Mediterranean herbs exhibit antioxidant activity towards iron promoted oxidation of phospholipids, linoleic acid, and deoxyribose. 2001 Free Radic. Res. pmid:11767417
Radschuweit A et al. Capillary zone electrophoresis with electrochemical detection--a simple and effective method to analyze oxygen-consuming and peroxide-forming processes. 2001 J Chromatogr A pmid:11765078
Yang H et al. Modulation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mutation in the cecum and colon of big blue rats by conjugated linoleic acid and 1,2-dithiole-3-thione. 2001 Nutr Cancer pmid:11759290
Ip C et al. Control of rat mammary epithelium proliferation by conjugated linoleic acid. 2001 Nutr Cancer pmid:11759286
Ohnuki K et al. Increased energy metabolism and suppressed body fat accumulation in mice by a low concentration of conjugated linoleic acid. 2001 Biosci. Biotechnol. Biochem. pmid:11758910
Mottaran E et al. Lipid peroxidation contributes to immune reactions associated with alcoholic liver disease. 2002 Free Radic. Biol. Med. pmid:11755315
Larqué E et al. Dietary trans fatty acids in early life: a review. 2001 Early Hum. Dev. pmid:11755033
Park Y and Pariza MW Lipoxygenase inhibitors inhibit heparin-releasable lipoprotein lipase activity in 3T3-L1 adipocytes and enhance body fat reduction in mice by conjugated linoleic acid. 2001 Biochim. Biophys. Acta pmid:11750884
Smith WG et al. Simple and rapid assessment of lipoprotein susceptibility to oxidation in the macromolecule fraction of plasma. 2002 Clin. Chim. Acta pmid:11750270
Smith WG et al. Lipoprotein susceptibility to oxidation in the macromolecular fraction of plasma: relation to plasma lipids and oleate/linoleate ratio in comparison with whole plasma in hypertriglyceridemia. 2002 Clin. Chim. Acta pmid:11750269
Pirtle IL et al. Molecular cloning and functional expression of the gene for a cotton Delta-12 fatty acid desaturase (FAD2). 2001 Biochim. Biophys. Acta pmid:11750064
Coles B et al. Nitrolinoleate inhibits platelet activation by attenuating calcium mobilization and inducing phosphorylation of vasodilator-stimulated phosphoprotein through elevation of cAMP. 2002 J. Biol. Chem. pmid:11748216
Melamed-Frank M et al. Structure-function analysis of the antioxidant properties of haptoglobin. 2001 Blood pmid:11739174
Büyükokuroğlu ME et al. In vitro antioxidant properties of dantrolene sodium. 2001 Pharmacol. Res. pmid:11735355
Fernández-Real JM et al. Circulating granulocyte-macrophage colony-stimulating factor and serum fatty acid composition in men and women. 2001 Metab. Clin. Exp. pmid:11735097
Pelikánová T et al. Serum phospholipid fatty acid composition and insulin action in type 2 diabetic patients. 2001 Metab. Clin. Exp. pmid:11735096
Gustafsson MC et al. Fatty-acid-displaced transcriptional repressor, a conserved regulator of cytochrome P450 102 transcription in Bacillus species. 2001 Arch. Microbiol. pmid:11734890
Watanabe T et al. Production and chemiluminescent free radical reactions of glyoxal in lipid peroxidation of linoleic acid by the ligninolytic enzyme, manganese peroxidase. 2001 Eur. J. Biochem. pmid:11733005
Lee BD et al. Nutritive and economic values of high oil corn in layer diet. 2001 Poult. Sci. pmid:11732667
Peters JM et al. Influence of conjugated linoleic acid on body composition and target gene expression in peroxisome proliferator-activated receptor alpha-null mice. 2001 Biochim. Biophys. Acta pmid:11731333
Park Y and Pariza MW The effects of dietary conjugated nonadecadienoic acid on body composition in mice. 2001 Biochim. Biophys. Acta pmid:11731328
Villalpando S et al. [13C]linoleic acid oxidation and transfer into milk in stunted lactating women with contrasting body mass indexes. 2001 Am. J. Clin. Nutr. pmid:11729835
Glew RH et al. Fatty acid composition of the milk lipids of Nepalese women: correlation between fatty acid composition of serum phospholipids and melting point. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728165
Thom E et al. Conjugated linoleic acid reduces body fat in healthy exercising humans. 2001 Sep-Oct J. Int. Med. Res. pmid:11725826
Cunnane SC Application of new methods and analytical approaches to research on polyunsaturated fatty acid homeostasis. 2001 Lipids pmid:11724470
Makrides M et al. Perinatal characteristics may influence the outcome of visual acuity. 2001 Lipids pmid:11724461
Calder PC Polyunsaturated fatty acids, inflammation, and immunity. 2001 Lipids pmid:11724453
Weber TE et al. Evaluation of conjugated linoleic acid and dietary antibiotics as growth promotants in weanling pigs. 2001 J. Anim. Sci. pmid:11721832
Milani G et al. Respiratory chain network in mitochondria of Candida parapsilosis: ADP/O appraisal of the multiple electron pathways. 2001 FEBS Lett. pmid:11718721
Palinski W et al. Maternal hypercholesterolemia and treatment during pregnancy influence the long-term progression of atherosclerosis in offspring of rabbits. 2001 Circ. Res. pmid:11717155